All Stories

  1. Mining single-cell time-series datasets with Time Course Inspector

    Article • Bioinformatics, November 2019, Oxford University Press (OUP)

    Dr Maciej Dobrzynski

  2. Temporal perturbation of ERK dynamics reveals network architecture of FGF2/MAPK signaling

    Article • Molecular Systems Biology, November 2019, EMBO

    Dr Maciej Dobrzynski

  3. Temporal perturbation of Erk dynamics reveals network architecture of FGF2-MAPK signaling

    Article • May 2019, Cold Spring Harbor Laboratory Press

    Dr Maciej Dobrzynski

  4. Automated Comparative Metabolite Profiling of Large LC-ESIMS Data Sets in an ACD/MS Workbook Suite Add-in, and Data Clustering on a New Open-Source Web Platform FreeClust

    Article • Analytical Chemistry, November 2017, American Chemical Society (ACS)

    Dr Maciej Dobrzynski

  5. Looking for specific natural inhibitors targeting aberrant proliferation signaling in melanoma

    Article • October 2017, Thieme Publishing Group

    Dr Maciej Dobrzynski

  6. Stabilization of C-RAF:KSR1 complex by DiRas3 reduces availability of C-RAF for dimerization with B-RAF

    Article • Cellular Signalling, October 2016, Elsevier

    Dr Maciej Dobrzynski

  7. Strategies for structuring interdisciplinary education in Systems Biology: an European perspective

    Article • npj Systems Biology and Applications, May 2016, Nature

    Dr Maciej Dobrzynski

  8. Frequency modulation of ERK activation dynamics rewires cell fate

    Article • Molecular Systems Biology, November 2015, EMBO

    Dr Maciej Dobrzynski

  9. Nonlinear signalling networks and cell-to-cell variability transform external signals into broadly distributed or bimodal responses

    Article • Journal of The Royal Society Interface, June 2014, Royal Society Publishing

    Dr Maciej Dobrzynski, Professor Boris N. Kholodenko

  10. Polyubiquitin chain assembly and organization determine the dynamics of protein activation and degradation

    Article • Frontiers in Physiology, January 2014, Frontiers

    Dr Maciej Dobrzynski, Professor Boris N. Kholodenko

  11. Emergence of bimodal cell population responses from the interplay between analog single-cell signaling and protein expression noise

    Article • BMC Systems Biology, August 2012, Springer Science + Business Media

    Marc Birtwistle, Dr Maciej Dobrzynski, Professor Boris N. Kholodenko

  12. Mammalian protein expression noise: scaling principles and the implications for knockdown experiments

    Article • Molecular BioSystems, January 2012, Royal Society of Chemistry

    Marc Birtwistle, Dr Maciej Dobrzynski, Professor Boris N. Kholodenko

  13. Bimodal Protein Distributions in Heterogeneous Oscillating Systems

    Article • January 2012, Springer Science + Business Media

    Dr Maciej Dobrzynski, Professor Boris N. Kholodenko

  14. Evolution of Bet-Hedging Mechanisms in Cell Cycle and Embryo Development Stimulated by Weak Linkage of Stochastic Processes

    Article • January 2011, Springer Science + Business Media

    Dr Maciej Dobrzynski

  15. Origins of Stochastic Intracellular Processes and Consequences for Cell-to-Cell Variability and Cellular Survival Strategies

    Article • January 2011, Elsevier

    Dr Maciej Dobrzynski

  16. Elongation dynamics shape bursty transcription and translation

    Article • Proceedings of the National Academy of Sciences, February 2009, Proceedings of the National Academy of Sciences

    Dr Maciej Dobrzynski

  17. Computational methods for diffusion-influenced biochemical reactions

    Article • Bioinformatics, May 2007, Oxford University Press (OUP)

    Dr Maciej Dobrzynski

  18. Spatial stochastic modelling of the phosphoenolpyruvate-dependent phosphotransferase (PTS) pathway in Escherichia coli

    Article • Bioinformatics, May 2006, Oxford University Press (OUP)

    Dr Maciej Dobrzynski