All Stories

  1. Potential therapeutics of Alzheimer's diseases: New insights into the neuroprotective role of trehalose-conjugated beta sheet breaker peptides
  2. Repurposing of Copper(II)-chelating Drugs for the Treatment of Neurodegenerative Diseases
  3. Influence of the N-terminus acetylation of Semax, a synthetic analog of ACTH(4-10), on copper(II) and zinc(II) coordination and biological properties
  4. Corrigendum: Ac-LPFFD-Th: A Trehalose-Conjugated Peptidomimetic as a Strong Suppressor of Amyloid-β Oligomer Formation and Cytotoxicity
  5. Copper(II) ions affect the gating dynamics of the 20S proteasome: a molecular and in cell study
  6. New Insight in Copper-Ion Binding to Human Islet Amyloid: The Contribution of Metal-Complex Speciation To Reveal the Polypeptide Toxicity
  7. Ac-LPFFD-Th: A Trehalose-Conjugated Peptidomimetic as a Strong Suppressor of Amyloid-β Oligomer Formation and Cytotoxicity
  8. Copper(ii) coordination properties of the Aβ(1–16)2peptidomimetic: experimental evidence of intermolecular macrochelate complex species in the Aβ dimer
  9. Monomeric ß-amyloid interacts with type-1 insulin-like growth factor receptors to provide energy supply to neurons
  10. Cross-Talk Between the Octarepeat Domain and the Fifth Binding Site of Prion Protein Driven by the Interaction of Copper(II) with the N-terminus
  11. On the Environmental Factors Affecting the Structural and Cytotoxic Properties of IAPP Peptides
  12. Semax, an ACTH4-10 peptide analog with high affinity for copper(II) ion and protective ability against metal induced cell toxicity
  13. Molecular and cytotoxic properties of hIAPP17–29 and rIAPP17–29 fragments: A comparative study with the respective full-length parent polypeptides
  14. The role of copper(ii) in the aggregation of human amylin
  15. The effect of non-coordinating side chains on the metal binding affinities of peptides of histidine
  16. Probing the Residual Structure in Avian Prion Hexarepeats by CD, NMR and MD Techniques
  17. Affinity, Speciation, and Molecular Features of Copper(II) Complexes with a Prion Tetraoctarepeat Domain in Aqueous Solution: Insights into Old and New Results
  18. Copper(ii) and zinc(ii) dependent effects on Aβ42 aggregation: a CD, Th-T and SFM study
  19. Metal ions affect insulin-degrading enzyme activity
  20. Interactions of Cu2+ with prion family peptide fragments: Considerations on affinity, speciation and coordination
  21. Copper(II) coordination properties of the integrin ligand sequence PHSRN and its new β-cyclodextrin conjugates
  22. Mixed metal copper(II)-nickel(II) and copper(II)-zinc(II) complexes of multihistidine peptide fragments of human prion protein
  23. Copper(II) interaction with amyloid-β: Affinity and speciation
  24. Zn2+’s Ability to Alter the Distribution of Cu2+ among the Available Binding Sites of Aβ(1–16)-Polyethylenglycol-ylated Peptide: Implications in Alzheimer’s Disease
  25. Copper(I) and Copper(II) Inhibit Aβ Peptides Proteolysis by Insulin-Degrading Enzyme Differently: Implications for Metallostasis Alteration in Alzheimer’s Disease
  26. Copper complex species within a fragment of the N-terminal repeat region in opossum PrP protein
  27. Copper(ii) complexes of rat amylin fragments
  28. The effect of point mutations on copper(II) complexes with peptide fragments encompassing the 106–114 region of human prion protein
  29. Membrane Interactions and Conformational Preferences of Human and Avian Prion N-Terminal Tandem Repeats: The Role of Copper(II) Ions, pH, and Membrane Mimicking Environments
  30. Nickel(II) complexes of the multihistidine peptide fragments of human prion protein
  31. Nickel(ii) and mixed metal complexes of amyloid-β N-terminus
  32. Surface immobilization of fibronectin-derived PHSRN peptide on functionalized polymer films – Effects on fibroblast spreading
  33. Aggregation Properties of the Peptide Fragments Derived from the 17-29 Region of the Human and Rat IAPP: A Comparative Study with Two PEG-Conjugated Variants of the Human Sequence
  34. Metal Loading Capacity of Aβ N-Terminus: a Combined Potentiometric and Spectroscopic Study of Zinc(II) Complexes with Aβ(1−16), Its Short or Mutated Peptide Fragments and Its Polyethylene Glycol−ylated Analogue
  35. Interaction of Copper(II) with the Prion Peptide Fragment HuPrP(76−114) Encompassing Four Histidyl Residues within and outside the Octarepeat Domain
  36. Copper(II) complexes with an avian prion N-terminal region and their potential SOD-like activity
  37. Copper(II) binding to two novel histidine-containing model hexapeptides: Evidence for a metal ion driven turn conformation
  38. The Metal Loading Ability of β-Amyloid N-Terminus: A Combined Potentiometric and Spectroscopic Study of Copper(II) Complexes with β-Amyloid(1−16), Its Short or Mutated Peptide Fragments, and Its Polyethylene Glycol (PEG)-ylated Analogue
  39. Carcinine-β-cyclodextrin derivatives as scavenger entities of OH radicals and SOD-like properties of their copper(II) complexes
  40. Unveiling the Role of Histidine and Tyrosine Residues on the Conformation of the Avian Prion Hexarepeat Domain
  41. Studies of nitric oxide interaction with mono- and dinuclear copper(ii) complexes of prion protein bis-octarepeat fragments
  42. Environmental Factors Differently Affect Human and Rat IAPP: Conformational Preferences and Membrane Interactions of IAPP17–29 Peptide Derivatives
  43. Copper(II) Interaction with Prion Peptide Fragments Encompassing Histidine Residues Within and Outside the Octarepeat Domain: Speciation, Stability Constants and Binding Details
  44. An NMR and molecular dynamics investigation of the avian prion hexarepeat conformational features in solution
  45. Determination of the Conformation of the Human VDAC1 N-Terminal Peptide, a Protein Moiety Essential for the Functional Properties of the Pore
  46. Nitrogen oxide interaction with copper complexes formed by small peptides belonging to the prion protein octa-repeat region
  47. Transition metal complexes of terminally protected peptides containing histidyl residues
  48. Conformational Properties and Functional Role of VDAC N-Terminal Peptide
  49. Environmental Effects on a Prion's Helix II Domain: Copper(II) and Membrane Interactions with PrP180–193 and Its Analogues
  50. Spectroscopic Characterization of PEG-Amylin Derivatives
  51. Copper(II) Interaction with Unstructured Prion Domain Outside the Octarepeat Region:  Speciation, Stability, and Binding Details of Copper(II) Complexes with PrP106−126 Peptides
  52. Copper(II) complexes with chicken prion repeats: influence of proline and tyrosine residues on the coordination features
  53. Synthesis and Structural Characterisation of Two Novel Diastereoisomeric Naproxen Appended β-Cyclodextrin Derivatives
  54. Conformational properties of peptide fragments homologous to the 106–114 and 106–126 residues of the human prion protein: a CD and NMR spectroscopic study
  55. A re-investigation of copper coordination in the octa-repeats region of the prion protein
  56. Copper(II) binding of prion protein’s octarepeat model peptides
  57. Copper(II) complexes of peptide fragments of the prion protein. Conformation changes induced by copper(II) and the binding motif in C-terminal protein region
  58. A thermodynamic and spectroscopic study on the copper(ii) complexes with hexarepeats fragments of the avian prion protein
  59. The interaction of a peptide with a scrambled hydrophobic/hydrophilic sequence (Pro-Asp-Ala-Asp-Ala-His-Ala-His-Ala-His-Ala-Ala-Ala-His-Gly) (PADH) with DPPC model membranes: a DSC study
  60. Copper(ii) and nickel(ii) binding modes in a histidine-containing model dodecapeptide
  61. Copper(II) Binding Modes in the Prion Octapeptide PHGGGWGQ: A Spectroscopic and Voltammetric Study
  62. Solid State and Solution Conformation of 6-{4-[N-tert-Butoxycarbonyl-N-(N-ethyl)propanamide]imidazolyl}-6-deoxycyclomaltoheptaose: Evidence of Self-Inclusion of the Boc Group within the β-Cyclodextrin Cavity
  63. Solid State and Solution Conformation of 6-{4-[N-tert-Butoxycarbonyl-N-(N′-ethyl)propanamide]imidazolyl}-6-deoxycyclomaltoheptaose: Evidence of Self-Inclusion of the Boc Group within the β-Cyclodextrin Cavity
  64. Solid State and Solution Conformation of 6-{4-[N-tert-Butoxycarbonyl-N-(N′-ethyl)propanamide]imidazolyl}-6-deoxycyclomaltoheptaose: Evidence of Self-Inclusion of the Boc Group within the β-Cyclodextrin Cavity
  65. Solid State and Solution Conformation of 6-[4-[N-tert-ButoxycarbonylN-(N′-ethyl)propanamide]imidazolyl]-6-deoxycyclomaltoheptaose: Evidence of Self-Inclusion of the Boc Group within the β-Cyclodextrin Cavity
  66. Synthesis, Spectroscopic Characterisation, and Metal Ion Interaction of a Newα-Helical Peptide
  67. Co-ordinating properties of cyclopeptides. Thermodynamic and spectroscopic study on the formation of copper(II) complexes with cyclo(Gly-His)4 and cyclo(Gly-His-Gly)2 and their superoxide dismutase-like activity
  68. Metal ion and proton stabilisation of turn motif in the synthetic octapeptide histidyltris(glycylhistidyl)glycine
  69. Synthesis and high field NMR study of a new cyclodipeptide–β-cyclodextrin derivative
  70. Copper(II) complexes with cyclo(L-aspartyl-L-aspartyl) and cyclo(L-glutamyl-L-glutamyl) derivatives and their antioxidant properties
  71. Weak forces in the thermodynamic stereoselectivity of proton and copper(II) complexes with diastereoisomeric dipeptides containing aromatic side chains
  72. Co-ordination properties of cyclopeptides. Formation and stability of zinc(II) and copper(II) complexes of histidine-containing cyclopeptides, or imidazole
  73. A new water soluble host compound possessing two different hydrophobic recognition cavities: Calix[4]arene derivative conjugated with monofunctionalized β-cyclodextrin
  74. Thermodynamic and spectroscopic characterization and in vitro O2 ? scavenger activity of copper(II) glycyl-L-histidyl-glycyl-L-histidine complexes
  75. Thermodynamic and 1H NMR study of proton complex formation of histidine-containing cyclodipeptides in aqueous solution
  76. Cyclopeptide functionalized β-cyclodextrin. A new class of potentially enzyme mimicking compounds with two recognition sites