All Stories

  1. Structure–function analysis of the nsp14 N7–guanine methyltransferase reveals an essential role inBetacoronavirusreplication

    Article • Proceedings of the National Academy of Sciences, November 2021, Proceedings of the National Academy of Sciences

    Professor Eric J. Snijder

  2. A unifying structural and functional model of the coronavirus replication organelle: Tracking down RNA synthesis

    Article • PLoS Biology, June 2020, PLOS

    Professor Eric J. Snijder

  3. Mutations in the chikungunya virus non-structural proteins cause resistance to favipiravir (T-705), a broad-spectrum antiviral

    Article • Journal of Antimicrobial Chemotherapy, June 2014, Oxford University Press (OUP)

    Professor Eric J. Snijder, Johan Neyts

  4. Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture

    Article • Antimicrobial Agents and Chemotherapy, May 2014, ASM Journals

    Professor Eric J. Snijder, Johan Neyts

  5. An Introduction to Nidoviruses

    Article • April 2014, ASM Journals

    Professor Eric J. Snijder

  6. RNA Signals Regulating Nidovirus RNA Synthesis

    Article • April 2014, ASM Journals

    Professor Eric J. Snijder

  7. Viral OTU Deubiquitinases: A Structural and Functional Comparison

    Article • PLoS Pathogens, March 2014, PLOS

    Professor Eric J. Snijder

  8. Inhibition of Dengue and Chikungunya Virus Infections by RIG-I-Mediated Type I Interferon-Independent Stimulation of the Innate Antiviral Response

    Article • Journal of Virology, January 2014, ASM Journals

    Professor Eric J. Snijder

  9. Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

    Article • Nature, November 2013, Springer Science + Business Media

    Professor Eric J. Snijder, Dr Donna A MacDuff

  10. 193

    Article • Cytokine, September 2013, Elsevier

    Professor Eric J. Snijder

  11. Arterivirus molecular biology and pathogenesis

    Article • Journal of General Virology, August 2013, Society for General Microbiology

    Professor Eric J. Snijder

  12. Characterization of Synthetic Chikungunya Viruses Based on the Consensus Sequence of Recent E1-226V Isolates

    Article • PLoS ONE, August 2013, PLOS

    Professor Eric J. Snijder

  13. The Footprint of Genome Architecture in the Largest Genome Expansion in RNA Viruses

    Article • PLoS Pathogens, July 2013, PLOS

    Professor Eric J. Snijder

  14. Arterivirus Serine Endopeptidase

    Article • January 2013, Elsevier

    Professor Eric J. Snijder

  15. Arterivirus nsp2 Cysteine Proteinase

    Article • January 2013, Elsevier

    Professor Eric J. Snijder

  16. Arterivirus Papain-like Proteinase 1α

    Article • January 2013, Elsevier

    Professor Eric J. Snijder

  17. Arterivirus Papain-like Proteinase 1β

    Article • January 2013, Elsevier

    Professor Eric J. Snijder

  18. Virus-Induced Remodeling of Intracellular Membranes: The Replication Structures of Nidoviruses and Enteroviruses

    Article • Microscopy and Microanalysis, July 2012, Oxford University Press (OUP)

    Professor Eric J. Snijder

  19. Development and Characterization of an Infectious cDNA Clone of the Modified Live Virus Vaccine Strain of Equine Arteritis Virus

    Article • Clinical and Vaccine Immunology, June 2012, ASM Journals

    Professor Eric J. Snijder

  20. Mechanism of Nucleic Acid Unwinding by SARS-CoV Helicase

    Article • PLoS ONE, May 2012, PLOS

    Professor Eric J. Snijder

  21. Mesoniviridae: a proposed new family in the order Nidovirales formed by a single species of mosquito-borne viruses

    Article • Archives of Virology, April 2012, Springer Science + Business Media

    Professor Eric J. Snijder, Dr Sandra Junglen

  22. Reverse Genetics of SARS-Related Coronavirus Using Vaccinia Virus-Based Recombination

    Article • PLoS ONE, March 2012, PLOS

    Professor Eric J. Snijder, Friedemann Weber

  23. Identification of porcine reproductive and respiratory syndrome virus ORF1a-encoded non-structural proteins in virus-infected cells

    Article • Journal of General Virology, January 2012, Society for General Microbiology

    Professor Eric J. Snijder

  24. Nonstructural Protein 2 of Porcine Reproductive and Respiratory Syndrome Virus Inhibits the Antiviral Function of Interferon-Stimulated Gene 15

    Article • Journal of Virology, January 2012, ASM Journals

    Professor Eric J. Snijder

  25. CS17-5. Arteri- and nairovirus OTU domain-containing proteases target ubiquitin-regulated factors in the RLR-mediated innate immune signaling pathway

    Article • Cytokine, October 2011, Elsevier

    Professor Eric J. Snijder

  26. Discovery of the First Insect Nidovirus, a Missing Evolutionary Link in the Emergence of the Largest RNA Virus Genomes

    Article • PLoS Pathogens, September 2011, PLOS

    Professor Eric J. Snijder

  27. European Training Network on (+)RNA Virus Replication and Antiviral Drug Development

    Article • Antiviral Research, May 2011, Elsevier

    Professor Eric J. Snijder, Johan Neyts

  28. Mass spectrometry-based comparative sequencing to detect ganciclovir resistance in the UL97 gene of human cytomegalovirus

    Article • Journal of Clinical Virology, May 2011, Elsevier

    Professor Eric J. Snijder

  29. Discovery of a small arterivirus gene that overlaps the GP5 coding sequence and is important for virus production

    Article • Journal of General Virology, February 2011, Society for General Microbiology

    Professor Eric J. Snijder

  30. Arterivirus‡

    Article • January 2011, Springer Science + Business Media

    Professor Eric J. Snijder

  31. Torovirus‡

    Article • January 2011, Springer Science + Business Media

    Professor Eric J. Snijder

  32. Characterization of Equine Humoral Antibody Response to the Nonstructural Proteins of Equine Arteritis Virus

    Article • Clinical and Vaccine Immunology, December 2010, ASM Journals

    Professor Eric J. Snijder

  33. The PRRSV replicase: Exploring the multifunctionality of an intriguing set of nonstructural proteins

    Article • Virus Research, December 2010, Elsevier

    Professor Eric J. Snijder

  34. Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture

    Article • PLoS Pathogens, November 2010, PLOS

    Professor Eric J. Snijder

  35. Papain-Like Protease 1 from Transmissible Gastroenteritis Virus: Crystal Structure and Enzymatic Activity toward Viral and Cellular Substrates

    Article • Journal of Virology, July 2010, ASM Journals

    Professor Eric J. Snijder

  36. Correction: In Vitro Reconstitution of SARS-Coronavirus mRNA Cap Methylation

    Article • PLoS Pathogens, May 2010, PLOS

    Professor Eric J. Snijder

  37. In Vitro Reconstitution of SARS-Coronavirus mRNA Cap Methylation

    Article • PLoS Pathogens, April 2010, PLOS

    Professor Eric J. Snijder

  38. The OrderNidovirales

    Article • March 2010, Wiley

    Professor Eric J. Snijder

  39. Coronaviruses, Toroviruses, and Arteriviruses

    Article • March 2010, Wiley

    Professor Eric J. Snijder

  40. Arterivirus Nsp1 Modulates the Accumulation of Minus-Strand Templates to Control the Relative Abundance of Viral mRNAs

    Article • PLoS Pathogens, February 2010, PLOS

    Professor Eric J. Snijder

  41. Structure of the X (ADRP) domain of nsp3 from feline coronavirus

    Article • Acta Crystallographica Section D Biological Crystallography, November 2009, International Union of Crystallography

    Professor Eric J. Snijder

  42. Integrity of the Early Secretory Pathway Promotes, but Is Not Required for, Severe Acute Respiratory Syndrome Coronavirus RNA Synthesis and Virus-Induced Remodeling of Endoplasmic Reticulum Membranes

    Article • Journal of Virology, November 2009, ASM Journals

    Professor Eric J. Snijder

  43. Myristoylation of the arterivirus E protein: the fatty acid modification is not essential for membrane association but contributes significantly to virus infectivity

    Article • Journal of General Virology, August 2009, Society for General Microbiology

    Professor Eric J. Snijder

  44. Structure of the C-terminal domain of nsp4 from feline coronavirus

    Article • Acta Crystallographica Section D Biological Crystallography, July 2009, International Union of Crystallography

    Professor Eric J. Snijder

  45. A Mass Spectrometry-based Method to Detect Antiviral Drug Resistance in Human Cytomegalovirus

    Article • Antiviral Research, May 2009, Elsevier

    Professor Eric J. Snijder

  46. Crystal structures of the X‐domains of a Group‐1 and a Group‐3 coronavirus reveal that ADP‐ribose‐binding may not be a conserved property

    Article • Protein Science, December 2008, Wiley

    Professor Eric J. Snijder

  47. SARS-Coronavirus Replication Is Supported by a Reticulovesicular Network of Modified Endoplasmic Reticulum

    Article • PLoS Biology, September 2008, PLOS

    Professor Eric J. Snijder

  48. SARS-Coronavirus Replication/Transcription Complexes Are Membrane-Protected and Need a Host Factor for Activity In Vitro

    Article • PLoS Pathogens, May 2008, PLOS

    Professor Eric J. Snijder

  49. The SARS-Coronavirus PLnc domain of nsp3 as a replication/transcription scaffolding protein

    Article • Virus Research, May 2008, Elsevier

    Professor Eric J. Snijder

  50. The nsp1  and nsp1 papain-like autoproteinases are essential for porcine reproductive and respiratory syndrome virus RNA synthesis

    Article • Journal of General Virology, February 2008, Society for General Microbiology

    Professor Eric J. Snijder

  51. Production of Monospecific Rabbit Antisera Recognizing Nidovirus Proteins

    Article • January 2008, Springer Science + Business Media

    Professor Eric J. Snijder

  52. Nidoviruses

    Article • December 2007, ASM Journals

    Professor Eric J. Snijder

  53. Genomic characterization of equine coronavirus

    Article • Virology, December 2007, Elsevier

    Professor Eric J. Snijder

  54. Ovarian Tumor Domain-Containing Viral Proteases Evade Ubiquitin- and ISG15-Dependent Innate Immune Responses

    Article • Cell Host & Microbe, December 2007, Elsevier

    Professor Eric J. Snijder

  55. An infectious recombinant equine arteritis virus expressing green fluorescent protein from its replicase gene

    Article • Journal of General Virology, April 2007, Society for General Microbiology

    Professor Eric J. Snijder

  56. Development and characterization of an infectious cDNA clone of the virulent Bucyrus strain of Equine arteritis virus

    Article • Journal of General Virology, March 2007, Society for General Microbiology

    Professor Eric J. Snijder

  57. Proteolytic maturation of replicase polyprotein pp1a by the nsp4 main proteinase is essential for equine arteritis virus replication and includes internal cleavage of nsp7

    Article • Journal of General Virology, December 2006, Society for General Microbiology

    Professor Eric J. Snijder

  58. Expression, purification, and in vitro activity of an arterivirus main proteinase

    Article • Virus Research, September 2006, Elsevier

    Professor Eric J. Snijder

  59. The non‐structural protein Nsp10 of mouse hepatitis virus binds zinc ions and nucleic acids

    Article • FEBS Letters, June 2006, Wiley

    Professor Eric J. Snijder

  60. Characterization of a Torovirus Main Proteinase

    Article • Journal of Virology, April 2006, ASM Journals

    Professor Eric J. Snijder

  61. Nidovirales: Evolving the largest RNA virus genome

    Article • Virus Research, April 2006, Elsevier

    Professor Eric J. Snijder

  62. Structural Protein Requirements in Equine Arteritis Virus Assembly

    Article • Journal of Virology, December 2004, ASM Journals

    Professor Eric J. Snijder

  63. Erratum to “Characterization of the neutralization determinants of equine arteritis virus using recombinant chimeric viruses and site-specific mutagenesis of an infectious cDNA clone” [Virology 321 (2004) 235–246]

    Article • Virology, October 2004, Elsevier

    Professor Eric J. Snijder

  64. Phage display of the Equine arteritis virus nsp1 ZF domain and examination of its metal interactions

    Article • Journal of Virological Methods, August 2004, Elsevier

    Professor Eric J. Snijder

  65. Characterization of the neutralization determinants of equine arteritis virus using recombinant chimeric viruses and site-specific mutagenesis of an infectious cDNA clone

    Article • Virology, April 2004, Elsevier

    Professor Eric J. Snijder

  66. The severe acute respiratory syndrome-coronavirus replicative protein nsp9 is a single-stranded RNA-binding subunit unique in the RNA virus world

    Article • Proceedings of the National Academy of Sciences, March 2004, Proceedings of the National Academy of Sciences

    Professor Eric J. Snijder, Helene Dutartre

  67. Structural genomics of the SARS coronavirus: cloning, expression, crystallization and preliminary crystallographic study of the Nsp9 protein

    Article • Acta Crystallographica Section D Biological Crystallography, August 2003, International Union of Crystallography

    Professor Eric J. Snijder

  68. Unique and Conserved Features of Genome and Proteome of SARS-coronavirus, an Early Split-off From the Coronavirus Group 2 Lineage

    Article • Journal of Molecular Biology, August 2003, Elsevier

    Professor Eric J. Snijder

  69. A Replication-Competent Chimera of Plant and Animal Viruses

    Article • Virology, March 2002, Elsevier

    Professor Eric J. Snijder

  70. Arteriviruses

    Article • January 2002, Wiley

    Professor Eric J. Snijder

  71. Construction of Chimeric Arteriviruses Reveals That the Ectodomain of the Major Glycoprotein Is Not the Main Determinant of Equine Arteritis Virus Tropism in Cell Culture

    Article • Virology, September 2001, Elsevier

    Professor Eric J. Snijder

  72. A zinc finger-containing papain-like protease couples subgenomic mRNA synthesis to genome translation in a positive-stranded RNA virus

    Article • Proceedings of the National Academy of Sciences, February 2001, Proceedings of the National Academy of Sciences

    Professor Eric J. Snijder

  73. Arterivirus RNA Synthesis Dissected

    Article • January 2001, Springer Science + Business Media

    Professor Eric J. Snijder

  74. Characterization of an Arterivirus Defective Interfering RNA

    Article • January 2001, Springer Science + Business Media

    Professor Eric J. Snijder

  75. Biochemical Characterization of the Equine Arteritis Virus Helicase Suggests a Close Functional Relationship between Arterivirus and Coronavirus Helicases

    Article • Journal of Virology, October 2000, ASM Journals

    Professor Eric J. Snijder

  76. Efficient Homologous RNA Recombination and Requirement for an Open Reading Frame during Replication of Equine Arteritis Virus Defective Interfering RNAs

    Article • Journal of Virology, October 2000, ASM Journals

    Professor Eric J. Snijder

  77. Characterization of Vaccinia Virus Intracellular Cores: Implications for Viral Uncoating and Core Structure

    Article • Journal of Virology, April 2000, ASM Journals

    Professor Eric J. Snijder

  78. Equine Arteritis Virus Derived from an Infectious cDNA Clone Is Attenuated and Genetically Stable in Infected Stallions

    Article • Virology, July 1999, Elsevier

    Professor Eric J. Snijder

  79. The Arterivirus Replicase

    Article • January 1998, Springer Science + Business Media

    Professor Eric J. Snijder

  80. Viral cysteine proteinases

    Article • Perspectives in Drug Discovery and Design, December 1996, Springer Science + Business Media

    Professor Eric J. Snijder

  81. Equine Arteritis Virus Subgenomic RNA Transcription: UV Inactivation and Translation Inhibition Studies

    Article • Virology, November 1995, Elsevier

    Professor Eric J. Snijder

  82. The Molecular Biology of Toroviruses

    Article • January 1995, Springer Science + Business Media

    Professor Eric J. Snijder

  83. The Coronaviruslike Superfamily

    Article • January 1995, Springer Science + Business Media

    Professor Eric J. Snijder

  84. Proteolytic Processing of the Arterivirus Replicase

    Article • January 1995, Springer Science + Business Media

    Professor Eric J. Snijder

  85. Proteolytic Processing of the N-terminal Region of the Equine Arteritis Virus Replicase

    Article • January 1994, Springer Science + Business Media

    Professor Eric J. Snijder

  86. The Coronaviruslike Superfamily

    Article • January 1994, Springer Science + Business Media

    Professor Eric J. Snijder

  87. Characterization of defective interfering RNAs of Berne virus

    Article • Journal of General Virology, July 1991, Society for General Microbiology

    Professor Eric J. Snijder

  88. Another triple-spanning envelope protein among intracellularly budding RNA viruses: The torovirus E protein

    Article • Virology, June 1991, Elsevier

    Professor Eric J. Snijder

  89. Comparison of the genome organization of toro- and coronaviruses: Evidence for two nonhomologous RNA recombination events during berne virus evolution

    Article • Virology, January 1991, Elsevier

    Professor Eric J. Snijder

  90. Primary structure and post-translational processing of the berne virus peplomer protein

    Article • Virology, October 1990, Elsevier

    Professor Eric J. Snijder

  91. The carboxyl-terminal part of the putative Berne virus polymerase is expressed by ribosomal frameshifting and contains sequence motifs which indicate that toro- and coronaviruses are evolutionary related

    Article • Nucleic Acids Research, August 1990, Oxford University Press (OUP)

    Professor Eric J. Snijder

  92. The Polymerase Gene of Corona- and Toroviruses: Evidence for an Evolutionary Relationship

    Article • January 1990, Springer Science + Business Media

    Professor Eric J. Snijder

  93. Identification and Primary Structure of the Gene Encoding the Berne Virus Nucleocapsid Protein

    Article • Journal of General Virology, December 1989, Society for General Microbiology

    Professor Eric J. Snijder

  94. Characterization of Berne Virus Genomic and Messenger RNAs

    Article • Journal of General Virology, September 1988, Society for General Microbiology

    Professor Eric J. Snijder

  95. The Arterivirus Replicase

    Article • ASM Journals

    Professor Eric J. Snijder

  96. Torovirus

    Article • Springer Science + Business Media

    Professor Eric J. Snijder

  97. Arterivirus

    Article • Springer Science + Business Media

    Professor Eric J. Snijder