All Stories

  1. The MST4–MOB4 complex disrupts the MST1–MOB1 complex in the Hippo–YAP pathway and plays a pro-oncogenic role in pancreatic cancer

    Article • Journal of Biological Chemistry, August 2018, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Zhubing Shi

  2. MST kinases in innate immune signaling

    Article • Cell Stress, January 2018, Shared Science Publishers OG

    Dr Zhubing Shi

  3. Exosome cofactor hMTR4 competes with export adaptor ALYREF to ensure balanced nuclear RNA pools for degradation and export

    Article • The EMBO Journal, August 2017, EMBO

    Dr Zhubing Shi

  4. DNA-binding mechanism of the Hippo pathway transcription factor TEAD4

    Article • Oncogene, April 2017, Nature

    Dr Zhubing Shi

  5. STRIPAK complexes in cell signaling and cancer

    Article • Oncogene, February 2016, Nature

    Dr Zhubing Shi

  6. Disruption of the RAG2 zinc finger motif impairs protein stability and causes immunodeficiency

    Article • European Journal of Immunology, January 2016, Wiley

    Dr Zhubing Shi

  7. A non‐canonical role of the p97 complex in RIG‐I antiviral signaling

    Article • The EMBO Journal, October 2015, EMBO

    Dr Zhubing Shi

  8. Structural Insights into Mitochondrial Antiviral Signaling Protein (MAVS)-Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) Signaling

    Article • Journal of Biological Chemistry, September 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Zhubing Shi

  9. The Transitional Endoplasmic Reticulum ATPase p97 Regulates the Alternative Nuclear Factor NF-κB Signaling via Partial Degradation of the NF-κB Subunit p100

    Article • Journal of Biological Chemistry, June 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Zhubing Shi

  10. The kinase MST4 limits inflammatory responses through direct phosphorylation of the adaptor TRAF6

    Article • Nature Immunology, February 2015, Springer Science + Business Media

    Dr Zhubing Shi

  11. Structural dissection of Hippo signaling

    Article • Acta Biochimica et Biophysica Sinica, December 2014, Oxford University Press (OUP)

    Dr Zhubing Shi

  12. Structural and Biochemical Insights into the Activation Mechanisms of Germinal Center Kinase OSR1

    Article • Journal of Biological Chemistry, November 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Zhubing Shi

  13. Structural Insights into the C1q Domain of Caprin-2 in Canonical Wnt Signaling

    Article • Journal of Biological Chemistry, October 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Zhubing Shi

  14. Structural insights into regulatory mechanisms of MO25-mediated kinase activation

    Article • Journal of Structural Biology, May 2014, Elsevier

    Dr Zhubing Shi

  15. Corrigendum to “Structure of MST2 SARAH domain provides insights into its interaction with RAPL” [J. Struct. Biol. 185 (2014) 366–374]

    Article • Journal of Structural Biology, April 2014, Elsevier

    Dr Zhubing Shi

  16. Structure of the kinase domain of Gilgamesh fromDrosophila melanogaster

    Article • Acta Crystallographica Section F Structural Biology Communications, March 2014, International Union of Crystallography

    Dr Zhubing Shi

  17. Structure of MST2 SARAH domain provides insights into its interaction with RAPL

    Article • Journal of Structural Biology, March 2014, Elsevier

    Dr Zhubing Shi

  18. A Peptide Mimicking VGLL4 Function Acts as a YAP Antagonist Therapy against Gastric Cancer

    Article • Cancer Cell, March 2014, Elsevier

    Dr Zhubing Shi

  19. Striatins Contain a Noncanonical Coiled Coil That Binds Protein Phosphatase 2A A Subunit to Form a 2:2 Heterotetrameric Core of Striatin-interacting Phosphatase and Kinase (STRIPAK) Complex

    Article • Journal of Biological Chemistry, February 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Zhubing Shi

  20. A Peptide Mimicking VGLL4 Function Acts as a YAP Antagonist Therapy against Gastric Cancer

    Article • Cancer Cell, February 2014, Elsevier

    Dr Zhubing Shi

  21. VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex

    Article • Cell Research, January 2014, Springer Science + Business Media

    Dr Zhubing Shi

  22. Structure of succinyl-CoA:3-ketoacid CoA transferase fromDrosophila melanogaster

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, September 2013, International Union of Crystallography

    Dr Zhubing Shi

  23. Structure of zebrafish MO25

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, August 2013, International Union of Crystallography

    Dr Zhubing Shi

  24. Structural Mechanism of CCM3 Heterodimerization with GCKIII Kinases

    Article • Structure, April 2013, Elsevier

    Dr Zhubing Shi

  25. Structure of PCNA fromDrosophila melanogaster

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, March 2013, International Union of Crystallography

    Dr Zhubing Shi

  26. Structure of the MST4 in Complex with MO25 Provides Insights into Its Activation Mechanism

    Article • Structure, March 2013, Elsevier

    Dr Zhubing Shi

  27. Structural and biochemical studies of RIG-I antiviral signaling

    Article • Protein & Cell, December 2012, Oxford University Press (OUP)

    Dr Zhubing Shi

  28. The Crystal Structure of Arabidopsis VSP1 Reveals the Plant Class C-Like Phosphatase Structure of the DDDD Superfamily of Phosphohydrolases

    Article • PLoS ONE, November 2012, PLOS

    Dr Zhubing Shi

  29. Germinal center kinases in immune regulation

    Article • Cellular and Molecular Immunology, September 2012, Springer Science + Business Media

    Dr Zhubing Shi

  30. Structural insights into SUN-KASH complexes across the nuclear envelope

    Article • Cell Research, September 2012, Springer Science + Business Media

    Dr Zhubing Shi

  31. Multiple Functions of Mammalian Germinal Center Kinases

    Article • Current Chemical Biology, May 2012, Bentham Science Publishers

    Dr Zhubing Shi

  32. Crystallization and preliminary crystallographic analysis of recombinant VSP1 fromArabidopsis thaliana

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, January 2010, International Union of Crystallography

    Dr Zhubing Shi