All Stories

  1. Practical Labeling Methodology for Choline‐Derived Lipids and Applications in Live Cell Fluorescence Imaging

    Article • Photochemistry and Photobiology, January 2014, Wiley

    Professor Christopher W Cairo

  2. Inhibitors of the human neuraminidase enzymes

    Article • MedChemComm, January 2014, Royal Society of Chemistry

    Professor Christopher W Cairo

  3. Conformational analysis of peramivir reveals critical differences between free and enzyme-bound states

    Article • MedChemComm, January 2014, Royal Society of Chemistry

    Professor Christopher W Cairo

  4. Synthesis of α-brominated phosphonates and their application as phosphate bioisosteres

    Article • MedChemComm, January 2014, Royal Society of Chemistry

    Professor Christopher W Cairo

  5. α-Bromophosphonate analogs of glucose-6-phosphate are inhibitors of glucose-6-phosphatase

    Article • Carbohydrate Research, November 2013, Elsevier

    Professor Christopher W Cairo

  6. Glycoform Remodeling Generates a Synthetic T Cell Phenotype

    Article • Bioconjugate Chemistry, June 2013, American Chemical Society (ACS)

    Professor Christopher W Cairo

  7. Identification of Selective Nanomolar Inhibitors of the Human Neuraminidase, NEU4

    Article • ACS Medicinal Chemistry Letters, May 2013, American Chemical Society (ACS)

    Professor Christopher W Cairo

  8. Identification of Selective Inhibitors for Human Neuraminidase Isoenzymes Using C4,C7-Modified 2-Deoxy-2,3-didehydro-N-acetylneuraminic Acid (DANA) Analogues

    Article • Journal of Medicinal Chemistry, March 2013, American Chemical Society (ACS)

    Professor Christopher W Cairo

  9. 5-(4-Hexyl-1H-1,2,3-triazol-1-yl)-2,1,3-benzoxadiazole

    Article • Acta Crystallographica Section E Structure Reports Online, October 2012, International Union of Crystallography

    Professor Christopher W Cairo

  10. 5-(1-Benzyl-1H-1,2,3-triazol-4-yl)-2,1,3-benzoxadiazole

    Article • Acta Crystallographica Section E Structure Reports Online, October 2012, International Union of Crystallography

    Professor Christopher W Cairo

  11. 1-[1-(2,1,3-Benzoxadiazol-5-ylmethyl)-1H-1,2,3-triazol-4-yl]hexan-1-one

    Article • Acta Crystallographica Section E Structure Reports Online, October 2012, International Union of Crystallography

    Professor Christopher W Cairo

  12. Protein–Glycosphingolipid Interactions Revealed Using Catch-and-Release Mass Spectrometry

    Article • Analytical Chemistry, September 2012, American Chemical Society (ACS)

    Professor Christopher W Cairo

  13. Detection of Cellular Sialic Acid Content Using Nitrobenzoxadiazole Carbonyl-Reactive Chromophores

    Article • Bioconjugate Chemistry, February 2012, American Chemical Society (ACS)

    Professor Christopher W Cairo

  14. Substituted Benzoxadiazoles as Fluorogenic Probes: A Computational Study of Absorption and Fluorescence

    Article • The Journal of Physical Chemistry A, December 2011, American Chemical Society (ACS)

    Professor Christopher W Cairo

  15. Substrate Recognition of the Membrane-Associated Sialidase NEU3 Requires a Hydrophobic Aglycone

    Article • Biochemistry, June 2011, American Chemical Society (ACS)

    Professor Christopher W Cairo

  16. Inhibitor selectivity of a new class of oseltamivir analogs against viral neuraminidase over human neuraminidase enzymes

    Article • Bioorganic & Medicinal Chemistry, May 2011, Elsevier

    Professor Christopher W Cairo

  17. Analysis of Molecular Diffusion by First-Passage Time Variance Identifies the Size of Confinement Zones

    Article • Biophysical Journal, March 2011, Elsevier

    Professor Christopher W Cairo

  18. Identification of fluorogenic and quenched benzoxadiazole reactive chromophores

    Article • Dyes and Pigments, January 2011, Elsevier

    Professor Christopher W Cairo

  19. Immobilization of carbohydrate epitopes for surface plasmon resonance using the Staudinger ligation

    Article • Carbohydrate Research, December 2010, Elsevier

    Professor Christopher W Cairo

  20. A protected l-bromophosphonomethylphenylalanine amino acid derivative (BrPmp) for synthesis of irreversible protein tyrosine phosphatase inhibitors

    Article • Bioorganic & Medicinal Chemistry, December 2010, Elsevier

    Professor Christopher W Cairo

  21. Inhibition of human neuraminidase 3 (NEU3) by C9-triazole derivatives of 2,3-didehydro-N-acetyl-neuraminic acid

    Article • Bioorganic & Medicinal Chemistry Letters, December 2010, Elsevier

    Professor Christopher W Cairo

  22. A Fluorogenic Aromatic Nucleophilic Substitution Reaction for Demonstrating Normal-Phase Chromatography and Isolation of Nitrobenzoxadiazole Chromophores

    Article • Journal of Chemical Education, October 2010, American Chemical Society (ACS)

    Professor Christopher W Cairo

  23. Conjugation of Synthetic N-Acetyl-Lactosamine to Azide-Containing Proteins Using the Staudinger Ligation

    Article • Bioconjugate Chemistry, September 2010, American Chemical Society (ACS)

    Professor Christopher W Cairo

  24. A Monomeric Photoconvertible Fluorescent Protein for Imaging of Dynamic Protein Localization

    Article • Journal of Molecular Biology, September 2010, Elsevier

    Professor Christopher W Cairo

  25. Fluorescent small-molecule probes of biochemistry at the plasma membrane

    Article • Current Opinion in Chemical Biology, February 2010, Elsevier

    Professor Christopher W Cairo

  26. A Hidden Markov Model for Single Particle Tracks Quantifies Dynamic Interactions between LFA-1 and the Actin Cytoskeleton

    Article • PLoS Computational Biology, November 2009, PLOS

    Professor Christopher W Cairo

  27. A Modular Synthesis of Alkynyl-Phosphocholine Headgroups for Labeling Sphingomyelin and Phosphatidylcholine

    Article • The Journal of Organic Chemistry, October 2009, American Chemical Society (ACS)

    Professor Christopher W Cairo

  28. Photophysical characterization of triazole-substituted coumarin fluorophores

    Article • Dyes and Pigments, August 2009, Elsevier

    Professor Christopher W Cairo

  29. 7,7′-(3,3′-Dibenzyl-3H,3′H-4,4′-bi-1,2,3-triazole-5,5′-diyl)bis(4-methyl-2H-chromen-2-one)

    Article • Acta Crystallographica Section E Structure Reports Online, September 2008, International Union of Crystallography

    Professor Christopher W Cairo

  30. T cell adhesion mechanisms revealed by receptor lateral mobility

    Article • Biopolymers, November 2007, Wiley

    Professor Christopher W Cairo

  31. Signaling by Committee: Receptor Clusters Determine Pathways of Cellular Activation

    Article • ACS Chemical Biology, October 2007, American Chemical Society (ACS)

    Professor Christopher W Cairo

  32. Analysis of Two-Dimensional Dissociation Constant of Laterally Mobile Cell Adhesion Molecules

    Article • Biophysical Journal, February 2007, Elsevier

    Professor Christopher W Cairo

  33. Mechanisms of Cellular Avidity Regulation in CD2–CD58-Mediated T Cell Adhesion

    Article • ACS Chemical Biology, November 2006, American Chemical Society (ACS)

    Professor Christopher W Cairo

  34. Cytoskeletal Regulation Couples LFA-1 Conformational Changes to Receptor Lateral Mobility and Clustering

    Article • Immunity, August 2006, Elsevier

    Professor Christopher W Cairo

  35. Visualization and Characterization of Receptor Clusters by Transmission Electron Microscopy

    Article • January 2003, Elsevier

    Professor Christopher W Cairo

  36. Influencing Receptor−Ligand Binding Mechanisms with Multivalent Ligand Architecture

    Article • Journal of the American Chemical Society, November 2002, American Chemical Society (ACS)

    Professor Christopher W Cairo

  37. Affinity-Based Inhibition of β-Amyloid Toxicity

    Article • Biochemistry, June 2002, American Chemical Society (ACS)

    Professor Christopher W Cairo

  38. Selective Immobilization of Multivalent Ligands for Surface Plasmon Resonance and Fluorescence Microscopy

    Article • Analytical Biochemistry, June 2002, Elsevier

    Professor Christopher W Cairo

  39. Hitting the sweet spot

    Article • Nature Biotechnology, March 2002, Springer Science + Business Media

    Professor Christopher W Cairo

  40. Control of Multivalent Interactions by Binding Epitope Density

    Article • Journal of the American Chemical Society, February 2002, American Chemical Society (ACS)

    Professor Christopher W Cairo

  41. Cell Aggregation by Scaffolded Receptor Clusters

    Article • Chemistry & Biology, February 2002, Elsevier

    Professor Christopher W Cairo