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  1. Rational Designed Hybrid Peptides Show up to a 6-Fold Increase in Antimicrobial Activity and Demonstrate Different Ultrastructural Changes as the Parental Peptides Measured by BioSAXS

    Article • Frontiers in Pharmacology, December 2021, Frontiers

    Prof Kai Hilpert

  2. Rational Designed Hybrid Peptides Show up to a 6-fold Increase in Antimicrobial Activity and Demonstrate Different Ultrastructural Changes as the Parental Peptides measured by BioSAXS

    Article • November 2021, Cold Spring Harbor Laboratory Press

    Prof Kai Hilpert

  3. Peptides that are used in COVID-19 Clinical Trials — A Snapshot

    Article • Biologics, October 2021, MDPI AG

    Prof Kai Hilpert

  4. Is the Gut Microbiome a Target for Adjuvant Treatment of COVID-19?

    Article • Biologics, September 2021, MDPI AG

    Prof Kai Hilpert

  5. Is There a Connection Between Gut Microbiome Dysbiosis in COVID-19 and Post-COVID-19 Symptoms?

    Article • Frontiers in Microbiology, September 2021, Frontiers

    Prof Kai Hilpert

  6. Rapid Assembly of Infection-Resistant Coatings: Screening and Identification of Antimicrobial Peptides Works in Cooperation with an Antifouling Background

    Article • ACS Applied Materials & Interfaces, July 2021, American Chemical Society (ACS)

    Prof Kai Hilpert

  7. Comparison of a Short Linear Antimicrobial Peptide with Its Disulfide-Cyclized and Cyclotide-Grafted Variants against Clinically Relevant Pathogens

    Article • Microorganisms, June 2021, MDPI AG

    Prof Kai Hilpert

  8. Antimicrobial Activity Of A Histone Derived Peptide In The Airway Surface Liquid

    Article • The FASEB Journal, May 2021, Wiley

    Prof Kai Hilpert

  9. Peptide Inhibitors of Bacterial Protein Synthesis with Broad Spectrum and SbmA-Independent Bactericidal Activity against Clinical Pathogens

    Article • Journal of Medicinal Chemistry, August 2020, American Chemical Society (ACS)

    Prof Kai Hilpert

  10. Identification Of A Novel Histone Derived Antimicrobial Peptide In Airway Surface Liquid.

    Article • The FASEB Journal, April 2020, Wiley

    Prof Kai Hilpert

  11. The effect of lipidation and glycosylation on short cationic antimicrobial peptides

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, March 2020, Elsevier

    Prof Kai Hilpert

  12. Front Cover: Proline‐Rich Peptides with Improved Antimicrobial Activity against E. coli , K. pneumoniae , and A. baumannii (ChemMedChem 24/2019)

    Article • ChemMedChem, December 2019, Wiley

    Prof Kai Hilpert

  13. Synergy Pattern of Short Cationic Antimicrobial Peptides Against Multidrug-Resistant Pseudomonas aeruginosa

    Article • Frontiers in Microbiology, November 2019, Frontiers

    Prof Kai Hilpert

  14. Proline‐Rich Peptides with Improved Antimicrobial Activity against E. coli , K. pneumoniae , and A. baumannii

    Article • ChemMedChem, November 2019, Wiley

    Prof Kai Hilpert

  15. Two antimicrobial peptides induce similar molecular changes in bacteria

    Article • Frontiers in Pharmacology, September 2019, Frontiers

    Prof Kai Hilpert

  16. Poster Session

    Article • Pediatric Pulmonology, September 2019, Wiley

    Prof Kai Hilpert

  17. In silicoidentification of novel peptides with antibacterial activity against multidrug resistantStaphylococcus aureus

    Article • March 2019, Cold Spring Harbor Laboratory Press

    Prof Kai Hilpert

  18. In silico identification of two novel antimicrobial peptides with antibacterial activity against multi-drug resistant Staphylococcus aureus

    Article • Access Microbiology, March 2019, Society for General Microbiology

    Prof Kai Hilpert

  19. The Savage Dawn Peptide: an antibiotic woven from 12th century Welsh poetry

    Article • Access Microbiology, March 2019, Society for General Microbiology

    Prof Kai Hilpert

  20. The Dolphin Proline-Rich Antimicrobial Peptide Tur1A Inhibits Protein Synthesis by Targeting the Bacterial Ribosome

    Article • Cell Chemical Biology, March 2018, Elsevier

    Prof Kai Hilpert

  21. The rumen microbiome: an underexplored resource for novel antimicrobial discovery

    Article • npj Biofilms and Microbiomes, December 2017, Nature

    Prof Kai Hilpert, Dr Christopher J Creevey, Professor Hilario C Mantovani

  22. Buwchitin: A Ruminal Peptide with Antimicrobial Potential against Enterococcus faecalis

    Article • Frontiers in Chemistry, July 2017, Frontiers

    Professor Hilario C Mantovani, Prof Kai Hilpert, Dr Christopher J Creevey

  23. A short artificial antimicrobial peptide shows potential to prevent or treat bone infections

    Article • Scientific Reports, May 2017, Springer Science + Business Media

    Prof Kai Hilpert

  24. Screening and Optimizing Antimicrobial Peptides by Using SPOT-Synthesis

    Article • Frontiers in Chemistry, April 2017, Frontiers

    Prof Kai Hilpert

  25. Improved Culture Medium (TiKa) for Mycobacterium avium Subspecies Paratuberculosis (MAP) Matches qPCR Sensitivity and Reveals Significant Proportions of Non-viable MAP in Lymphoid Tissue of Vaccinated MAP Challenged Animals

    Article • Frontiers in Microbiology, January 2017, Frontiers

    Prof Kai Hilpert

  26. Use of Peptide Libraries for Identification and Optimization of Novel Antimicrobial Peptides

    Article • Current Topics in Medicinal Chemistry, December 2016, Bentham Science Publishers

    Prof Kai Hilpert

  27. Molecular changes in E. coli after treatment with different antibiotics

    Article • Journal of Applied Crystallography, December 2016, International Union of Crystallography

    Prof Kai Hilpert

  28. Antimicrobial peptides: Cell Membrane and Microbial Surface Interactions

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, May 2016, Elsevier

    Prof Kai Hilpert

  29. Improving short antimicrobial peptides despite elusive rules for activity

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, May 2016, Elsevier

    Prof Kai Hilpert

  30. Small angle X-ray scattering as a high-throughput method to classify antimicrobial modes of action

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, May 2016, Elsevier

    Prof Kai Hilpert

  31. Alternatives to antibiotics—a pipeline portfolio review

    Article • The Lancet Infectious Diseases, February 2016, Elsevier

    Prof Kai Hilpert

  32. Interaction of blood components with cathelicidins and their modified versions

    Article • Biomaterials, November 2015, Elsevier

    Prof Kai Hilpert

  33. Optimization of oncocin for antibacterial activity using a SPOT synthesis approach: extending the pathogen spectrum to Staphylococcus aureus

    Article • Amino Acids, September 2015, Springer Science + Business Media

    Prof Kai Hilpert

  34. Cationic antimicrobial peptides as potential new therapeutic agents in neonates and children

    Article • Current Opinion in Infectious Diseases, June 2014, Wolters Kluwer Health

    Prof Kai Hilpert

  35. Targeting Mycobacterium tuberculosis and Other Microbial Pathogens Using Improved Synthetic Antibacterial Peptides

    Article • Antimicrobial Agents and Chemotherapy, March 2013, ASM Journals

    Santiago Ramon Garcia, Prof Kai Hilpert

  36. A Novel Monoclonal Antibody Against the C-terminus of β-Tubulin Recognizes Endocytic Organelles in Trypanosoma cruzi

    Article • Protein and Peptide Letters, April 2012, Bentham Science Publishers

    Professor Sergio Schenkman, Prof Kai Hilpert

  37. The biocompatibility and biofilm resistance of implant coatings based on hydrophilic polymer brushes conjugated with antimicrobial peptides

    Article • Biomaterials, June 2011, Elsevier

    Dr Robert E Hancock, Prof Kai Hilpert

  38. Identifying Novel Antimicrobial Peptides with Therapeutic Potential Against Multidrug-Resistant Bacteria by Using the SPOT Synthesis

    Article • Mini-Reviews in Organic Chemistry, May 2011, Bentham Science Publishers

    Prof Kai Hilpert

  39. SPOT Synthesis as a Tool to Study Protein–Protein Interactions

    Article • January 2011, Springer Science + Business Media

    Prof Kai Hilpert

  40. Screening for Antifungal Peptides and Their Modes of Action in Aspergillus nidulans

    Article • Applied and Environmental Microbiology, September 2010, ASM Journals

    Prof Kai Hilpert

  41. Structural Studies of a Peptide with Immune Modulating and Direct Antimicrobial Activity

    Article • Chemistry & Biology, September 2010, Elsevier

    Dr Robert E Hancock, Prof Kai Hilpert

  42. Short Cationic Antimicrobial Peptides Interact with ATP

    Article • Antimicrobial Agents and Chemotherapy, July 2010, ASM Journals

    Prof Kai Hilpert

  43. Easy Strategy To Protect Antimicrobial Peptides from Fast Degradation in Serum

    Article • Antimicrobial Agents and Chemotherapy, June 2010, ASM Journals

    Prof Kai Hilpert

  44. Posters

    Article • Journal of Peptide Science, January 2010, Wiley

    Prof Kai Hilpert

  45. Synthesis of Antimicrobial Peptides Using the SPOT Technique

    Article • September 2009, Springer Science + Business Media

    Prof Kai Hilpert

  46. High-Throughput Screening for Antimicrobial Peptides Using the SPOT Technique

    Article • September 2009, Springer Science + Business Media

    Prof Kai Hilpert

  47. Synergistic Interaction between Silver Nanoparticles and Membrane-Permeabilizing Antimicrobial Peptides

    Article • Antimicrobial Agents and Chemotherapy, June 2009, ASM Journals

    Prof Kai Hilpert

  48. Identification of Novel Antibacterial Peptides by Chemoinformatics and Machine Learning †

    Article • Journal of Medicinal Chemistry, April 2009, American Chemical Society (ACS)

    Dr Robert E Hancock, Prof Kai Hilpert

  49. Interpretable Features for the Activity Prediction of Short Antimicrobial Peptides Using Fuzzy Logic

    Article • International Journal of Peptide Research and Therapeutics, March 2009, Springer Science + Business Media

    Prof Kai Hilpert

  50. Use of Artificial Intelligence in the Design of Small Peptide Antibiotics Effective against a Broad Spectrum of Highly Antibiotic-Resistant Superbugs

    Article • ACS Chemical Biology, January 2009, American Chemical Society (ACS)

    Dr Robert E Hancock, Prof Kai Hilpert

  51. Synthesis of Peptide Arrays Using SPOT-Technology and the CelluSpots-Method

    Article • January 2009, Springer Science + Business Media

    Dr Robert E Hancock, Prof Kai Hilpert

  52. Screening and Characterization of Surface-Tethered Cationic Peptides for Antimicrobial Activity

    Article • Chemistry & Biology, January 2009, Elsevier

    Prof Kai Hilpert

  53. Identification of novel host defense peptides and the absence of α-defensins in the bovine genome

    Article • Proteins Structure Function and Bioinformatics, April 2008, Wiley

    Dr Robert E Hancock, Prof Kai Hilpert

  54. Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances

    Article • Nature Protocols, January 2008, Springer Science + Business Media

    Dr Robert E Hancock, Prof Kai Hilpert

  55. X-ray spectromicroscopy study of competitive adsorption of protein and peptide onto polystyrene-poly(methyl methacrylate)

    Article • Biointerphases, January 2008, American Vacuum Society

    Dr Robert E Hancock, Prof Kai Hilpert

  56. Short Linear Cationic Antimicrobial Peptides: Screening, Optimizing, and Prediction

    Article • January 2008, Springer Science + Business Media

    Prof Kai Hilpert

  57. Evaluating Different Descriptors for Model Design of Antimicrobial Peptides with Enhanced Activity Toward P. aeruginosa

    Article • Chemical Biology & Drug Design, August 2007, Wiley

    Prof Kai Hilpert

  58. Using Intrinsic X-ray Absorption Spectral Differences To Identify and Map Peptides and Proteins

    Article • The Journal of Physical Chemistry, July 2007, American Chemical Society (ACS)

    Dr Robert E Hancock, Prof Kai Hilpert

  59. Use of luminescent bacteria for rapid screening and characterization of short cationic antimicrobial peptides synthesized on cellulose using peptide array technology

    Article • Nature Protocols, June 2007, Springer Science + Business Media

    Dr Robert E Hancock, Prof Kai Hilpert

  60. Peptide arrays on cellulose support: SPOT synthesis, a time and cost efficient method for synthesis of large numbers of peptides in a parallel and addressable fashion

    Article • Nature Protocols, May 2007, Springer Science + Business Media

    Dr Robert E Hancock, Prof Kai Hilpert

  61. Sequence Requirements and an Optimization Strategy for Short Antimicrobial Peptides

    Article • Chemistry & Biology, October 2006, Elsevier

    Dr Robert E Hancock, Prof Kai Hilpert

  62. Complete Substitutional Analysis of a Sunflower Trypsin Inhibitor with Different Serine Proteases

    Article • The Journal of Biochemistry, October 2005, Oxford University Press (OUP)

    Prof Kai Hilpert

  63. High-throughput generation of small antibacterial peptides with improved activity

    Article • Nature Biotechnology, July 2005, Springer Science + Business Media

    Dr Robert E Hancock, Prof Kai Hilpert

  64. Unraveling Sub-Site Specificities of Peptidic Serine Protease Inhibitors by Substitutional and Structural Analysis

    Article • Protein and Peptide Letters, July 2005, Bentham Science Publishers

    Prof Kai Hilpert

  65. Crystallization and Preliminary X-ray Analysis of Complexes of Porcine Pancreatic Elastase with two Natural Inhibitors

    Article • Protein and Peptide Letters, August 2004, Bentham Science Publishers

    Prof Kai Hilpert

  66. Design and Characterization of a Hybrid Miniprotein That Specifically Inhibits Porcine Pancreatic Elastase

    Article • Journal of Biological Chemistry, April 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Kai Hilpert

  67. Structure of a hybrid squash inhibitor in complex with porcine pancreatic elastase at 1.8 Å resolution

    Article • Acta Crystallographica Section D Biological Crystallography, January 2003, International Union of Crystallography

    Prof Kai Hilpert

  68. Crystallization and preliminary X-ray analysis of the complex of porcine pancreatic elastase and a hybrid squash inhibitor

    Article • Acta Crystallographica Section D Biological Crystallography, March 2002, International Union of Crystallography

    Prof Kai Hilpert

  69. Anti-c-myc antibody 9E10: epitope key positions and variability characterized using peptide spot synthesis on cellulose

    Article • Protein Engineering Design and Selection, October 2001, Oxford University Press (OUP)

    Prof Kai Hilpert

  70. Characterizing and Optimizing Protease/Peptide Inhibitor Interactions, a New Application for Spot Synthesis

    Article • The Journal of Biochemistry, December 2000, Oxford University Press (OUP)

    Prof Kai Hilpert

  71. Atomic resolution structure of native porcine pancreatic elastase at 1.1 Å

    Article • Acta Crystallographica Section D Biological Crystallography, April 2000, International Union of Crystallography

    Prof Kai Hilpert

  72. Interaction of the Capsid Protein p24 (HIV-1) with Sequence-Derived Peptides: Influence on p24 Dimerization

    Article • Virology, February 1999, Elsevier

    Prof Kai Hilpert