All Stories

  1. Inhibition of vaccinia virus L1 N-myristoylation by the host N-myristoyltransferase inhibitor IMP-1088 generates non-infectious virions defective in cell entry

    Article • PLoS Pathogens, October 2022, PLOS

    Professor Edward W Tate

  2. Inhibition of protein N-myristoylation blocks Plasmodium falciparum intraerythrocytic development, egress and invasion

    Article • PLoS Biology, October 2021, PLOS

    Professor Edward W Tate

  3. New developments in probing and targeting protein acylation in malaria, leishmaniasis and African sleeping sickness

    Article • Parasitology, March 2017, Cambridge University Press

    Professor Edward W Tate

  4. Microfluidic Mobility Shift Assay for Real-Time Analysis of Peptide N-Palmitoylation

    Article • SLAS DISCOVERY, January 2017, SAGE Publications

    Professor Edward W Tate

  5. Direct Targeting of the Ras GTPase Superfamily Through Structure- Based Design

    Article • Current Topics in Medicinal Chemistry, November 2016, Bentham Science Publishers

    Professor Edward W Tate

  6. Discovery of high affinity inhibitors of Leishmania donovani N-myristoyltransferase

    Article • MedChemComm, January 2015, Royal Society of Chemistry

    Professor Edward W Tate

  7. Discovery of pyridyl-based inhibitors of Plasmodium falciparum N-myristoyltransferase

    Article • MedChemComm, January 2015, Royal Society of Chemistry

    Professor Edward W Tate

  8. A succinyl lysine-based photo-cross-linking peptide probe for Sirtuin 5

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Professor Edward W Tate

  9. New chemical probes targeting cholesterylation of Sonic Hedgehog in human cells and zebrafish

    Article • Chemical Science, January 2014, Royal Society of Chemistry

    Professor Edward W Tate

  10. Peptidomimetic inhibitors ofN-myristoyltransferase from human malaria and leishmaniasis parasites

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Professor Edward W Tate

  11. N-Myristoyltransferase as a potential drug target in malaria and leishmaniasis

    Article • Parasitology, April 2013, Cambridge University Press

    Professor Edward W Tate