All Stories

  1. Structure of monomeric full-length ARC sheds light on molecular flexibility, protein interactions, and functional modalities

    Article • Journal of Neurochemistry, September 2018, Wiley

    Dr Petri Kursula

  2. Structural basis for PDZ domain interactions in the post-synaptic density scaffolding protein Shank3

    Article • Journal of Neurochemistry, June 2018, Wiley

    Dr Petri Kursula

  3. The many structural faces of calmodulin: a multitasking molecular jackknife

    Article • Amino Acids, July 2014, Springer Science + Business Media

    Dr Petri Kursula

  4. A role of peripheral myelin protein 2 in lipid homeostasis of myelinating schwann cells

    Article • Glia, May 2014, Wiley

    Dr Petri Kursula

  5. The myelin membrane-associated enzyme 2′,3′-cyclic nucleotide 3′-phosphodiesterase: on a highway to structure and function

    Article • Neuroscience Bulletin, May 2014, Springer Science + Business Media

    Dr Petri Kursula

  6. Structural and dynamical properties of reconstituted myelin sheaths in the presence of myelin proteins MBP and P2 studied by neutron scattering

    Article • Soft Matter, January 2014, Royal Society of Chemistry

    Dr Petri Kursula

  7. Atomic resolution view into the structure–function relationships of the human myelin peripheral membrane protein P2

    Article • Acta Crystallographica Section D Biological Crystallography, December 2013, International Union of Crystallography

    Dr Petri Kursula

  8. Crystallographic snapshots of initial steps in the collapse of the calmodulin central helix

    Article • Acta Crystallographica Section D Biological Crystallography, December 2013, International Union of Crystallography

    Dr Petri Kursula

  9. The Structural Motifs for Substrate Binding and Dimerization of the α Subunit of Collagen Prolyl 4-Hydroxylase

    Article • Structure, December 2013, Elsevier

    Dr Petri Kursula

  10. Lipid Membrane Association of Myelin Proteins and Peptide Segments Studied by Oriented and Synchrotron Radiation Circular Dichroism Spectroscopy

    Article • The Journal of Physical Chemistry B, November 2013, American Chemical Society (ACS)

    Dr Petri Kursula

  11. Crystallographic Analysis of the Reaction Cycle of 2′,3′-Cyclic Nucleotide 3′-Phosphodiesterase, a Unique Member of the 2H Phosphoesterase Family

    Article • Journal of Molecular Biology, November 2013, Elsevier

    Dr Petri Kursula, Dr Huijong Han

  12. Recombinant production, crystallization and preliminary structural characterization ofSchistosoma japonicumprofilin

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, October 2013, International Union of Crystallography

    Dr Petri Kursula

  13. Preliminary crystallographic analysis of the N-terminal PDZ-like domain of periaxin, an abundant peripheral nerve protein linked to human neuropathies

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, June 2013, International Union of Crystallography

    Dr Petri Kursula, Dr Huijong Han

  14. Recognition of Mono-ADP-Ribosylated ARTD10 Substrates by ARTD8 Macrodomains

    Article • Structure, March 2013, Elsevier

    Dr Petri Kursula

  15. Myelin‐specific proteins: A structurally diverse group of membrane‐interacting molecules

    Article • BioFactors, January 2013, Wiley

    Dr Petri Kursula, Dr Huijong Han

  16. Membrane Interactions, Intrinsic Disorder, and Unknown Functions of Myelin Proteins

    Article • Biophysical Journal, January 2013, Elsevier

    Dr Petri Kursula, Dr Huijong Han

  17. The Influence of the Myelin Basic Protein C8 Mutant on the Dynamics of Myelin Membranes

    Article • Journal of the Physical Society of Japan, January 2013, Physical Society of Japan

    Dr Petri Kursula

  18. Juxtanodin is an intrinsically disordered F-actin-binding protein

    Article • Scientific Reports, November 2012, Springer Science + Business Media

    Dr Petri Kursula

  19. Production and crystallization of a panel of structure-based mutants of the human myelin peripheral membrane protein P2

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, October 2012, International Union of Crystallography

    Dr Petri Kursula

  20. The N‐terminal domain of the myelin enzyme 2′,3′‐cyclic nucleotide 3′‐phosphodiesterase: direct molecular interaction with the calcium sensor calmodulin

    Article • Journal of Neurochemistry, September 2012, Wiley

    Dr Petri Kursula

  21. Interactions of calmodulin with death-associated protein kinase peptides: experimental and modeling studies

    Article • Journal of Biomolecular Structure and Dynamics, May 2012, Taylor & Francis

    Dr Petri Kursula

  22. The Lasso Segment Is Required for Functional Dimerization of the Plasmodium Formin 1 FH2 Domain

    Article • PLoS ONE, March 2012, PLOS

    Dr Petri Kursula

  23. Myelin 2′,3′-Cyclic Nucleotide 3′-Phosphodiesterase: Active-Site Ligand Binding and Molecular Conformation

    Article • PLoS ONE, February 2012, PLOS

    Dr Petri Kursula, Dr Huijong Han

  24. Effects of Gigapascal Level Pressure on Protein Structure and Function

    Article • The Journal of Physical Chemistry B, January 2012, American Chemical Society (ACS)

    Dr Petri Kursula

  25. Structure and Function of the Peripheral Membrane Protein P2 from Human Nervous System Myelin

    Article • Biophysical Journal, January 2012, Elsevier

    Dr Petri Kursula

  26. Cofactor mobility determines reaction outcome in the IMPDH and GMPR (β-α)8 barrel enzymes

    Article • Nature Chemical Biology, October 2011, Springer Science + Business Media

    Dr Petri Kursula

  27. Structure of the Dimeric Autoinhibited Conformation of DAPK2, a Pro-Apoptotic Protein Kinase

    Article • Journal of Molecular Biology, June 2011, Elsevier

    Dr Petri Kursula

  28. Charge Isomers of Myelin Basic Protein: Structure and Interactions with Membranes, Nucleotide Analogues, and Calmodulin

    Article • PLoS ONE, May 2011, PLOS

    Dr Petri Kursula

  29. Clinical and molecular characterization of five patients with succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, May 2011, Elsevier

    Dr Petri Kursula, Professor Can Ficicioglu

  30. Purification, crystallization and preliminary X-ray crystallographic analysis of MIL, a glycosylated jacalin-related lectin from mulberry (Morus indica) latex

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, April 2011, International Union of Crystallography

    Dr Petri Kursula

  31. Conformations of peptides derived from myelin-specific proteins in membrane-mimetic conditions probed by synchrotron radiation CD spectroscopy

    Article • Amino Acids, April 2011, Springer Science + Business Media

    Dr Petri Kursula

  32. A neonatal‐onset succinyl‐CoA:3‐ketoacid CoA transferase (SCOT)‐deficient patient with T435N and c.658‐666dupAACGTGATT p.N220_I222dup mutations in the OXCT1 gene

    Article • Journal of Inherited Metabolic Disease, July 2010, Wiley

    Dr Petri Kursula

  33. Erratum to: Structural analysis of the complex between calmodulin and full-length myelin basic protein, an intrinsically disordered molecule

    Article • Amino Acids, May 2010, Springer Science + Business Media

    Dr Petri Kursula

  34. Structural and Functional Characterization of Human Peripheral Nervous System Myelin Protein P2

    Article • PLoS ONE, April 2010, PLOS

    Dr Petri Kursula

  35. Myelin Basic Protein and Myelin Protein 2 Act Synergistically to Cause Stacking of Lipid Bilayers

    Article • Biochemistry, April 2010, American Chemical Society (ACS)

    Dr Petri Kursula

  36. Purification of recombinant growth hormone by clear native gels for conformational analyses: preservation of conformation and receptor binding

    Article • Amino Acids, March 2010, Springer Science + Business Media

    Dr Petri Kursula

  37. Expression, purification, and initial characterization of different domains of recombinant mouse 2',3'-cyclic nucleotide 3'-phosphodiesterase, an enigmatic enzyme from the myelin sheath

    Article • BMC Research Notes, January 2010, Springer Science + Business Media

    Dr Petri Kursula

  38. The Thiolase Reaction Mechanism: The Importance of Asn316 and His348 for Stabilizing the Enolate Intermediate of the Claisen Condensation

    Article • Biochemistry, October 2009, American Chemical Society (ACS)

    Dr Petri Kursula

  39. Structural analysis of the complex between calmodulin and full-length myelin basic protein, an intrinsically disordered molecule

    Article • Amino Acids, October 2009, Springer Science + Business Media

    Dr Petri Kursula

  40. Complex formation between calmodulin and a peptide from the intracellular loop of the gap junction protein connexin43: Molecular conformation and energetics of binding

    Article • Biophysical Chemistry, October 2009, Elsevier

    Dr Petri Kursula

  41. Testis-expressed profilins 3 and 4 show distinct functional characteristics and localize in the acroplaxome-manchette complex in spermatids

    Article • BMC Cell Biology, May 2009, Springer Science + Business Media

    Dr Petri Kursula

  42. Domain Swapping and Different Oligomeric States for the Complex Between Calmodulin and the Calmodulin-Binding Domain of Calcineurin A

    Article • PLoS ONE, April 2009, PLOS

    Dr Petri Kursula

  43. Accurate Solution Structures of Proteins from X-ray Data and a Minimal Set of NMR Data: Calmodulin−Peptide Complexes As Examples

    Article • Journal of the American Chemical Society, March 2009, American Chemical Society (ACS)

    Dr Petri Kursula, Professor Claudio Luchinat

  44. Structure, modifications and ligand-binding properties of rat profilin 2a

    Article • Acta Crystallographica Section D Biological Crystallography, March 2009, International Union of Crystallography

    Dr Petri Kursula

  45. The sulfur atoms of the substrate CoA and the catalytic cysteine are required for a productive mode of substrate binding in bacterial biosynthetic thiolase, a thioester‐dependent enzyme

    Article • FEBS Journal, November 2008, Wiley

    Dr Petri Kursula

  46. Structural Basis for Parasite-Specific Functions of the Divergent Profilin of Plasmodium falciparum

    Article • Structure, November 2008, Elsevier

    Dr Petri Kursula

  47. Crystal and solution structure, stability and post‐translational modifications of collapsin response mediator protein 2

    Article • FEBS Journal, August 2008, Wiley

    Dr Petri Kursula

  48. Interaction between the C-terminal region of human myelin basic protein and calmodulin: analysis of complex formation and solution structure

    Article • BMC Structural Biology, February 2008, Springer Science + Business Media

    Dr Petri Kursula

  49. High-resolution Structural Analysis of Mammalian Profilin 2a Complex Formation with Two Physiological Ligands: The Formin Homology 1 Domain of mDia1 and the Proline-rich Domain of VASP

    Article • Journal of Molecular Biology, January 2008, Elsevier

    Dr Petri Kursula

  50. Identification and characterization of a temperature-sensitive R268H mutation in the human succinyl-CoA:3-ketoacid CoA transferase (SCOT) gene

    Article • Molecular Genetics and Metabolism, November 2007, Elsevier

    Dr Petri Kursula

  51. A structural insight into lead neurotoxicity and calmodulin activation by heavy metals

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, July 2007, International Union of Crystallography

    Dr Petri Kursula

  52. A previously unobserved conformation for the human Pex5p receptor suggests roles for intrinsic flexibility and rigid domain motions in ligand binding

    Article • BMC Structural Biology, April 2007, Springer Science + Business Media

    Dr Petri Kursula

  53. The structure of human collapsin response mediator protein 2, a regulator of axonal growth

    Article • Journal of Neurochemistry, December 2006, Wiley

    Dr Petri Kursula

  54. Recognition of a Functional Peroxisome Type 1 Target by the Dynamic Import Receptor Pex5p

    Article • Molecular Cell, December 2006, Elsevier

    Dr Petri Kursula

  55. Structures of the hydrolase domain of human 10-formyltetrahydrofolate dehydrogenase and its complex with a substrate analogue

    Article • Acta Crystallographica Section D Biological Crystallography, October 2006, International Union of Crystallography

    Dr Petri Kursula

  56. Structure of the synthetase domain of human CTP synthetase, a target for anticancer therapy

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, June 2006, International Union of Crystallography

    Dr Petri Kursula

  57. Structure and Function of the Myelin Proteins: Current Status and Perspectives in Relation to Multiple Sclerosis

    Article • Current Medicinal Chemistry, June 2005, Bentham Science Publishers

    Dr Petri Kursula

  58. High Resolution Crystal Structures of Human Cytosolic Thiolase (CT): A Comparison of the Active Sites of Human CT, Bacterial Thiolase, and Bacterial KAS I

    Article • Journal of Molecular Biology, March 2005, Elsevier

    Dr Petri Kursula

  59. XDSi: a graphical interface for the data processing programXDS

    Article • Journal of Applied Crystallography, March 2004, International Union of Crystallography

    Dr Petri Kursula

  60. Crystallization of the proline-rich-peptide binding domain of human type I collagen prolyl 4-hydroxylase

    Article • Acta Crystallographica Section D Biological Crystallography, April 2003, International Union of Crystallography

    Dr Petri Kursula

  61. Crystallization and preliminary X-ray diffraction studies of an α-methylacyl-CoA racemase fromMycobacterium tuberculosis

    Article • Acta Crystallographica Section D Biological Crystallography, January 2003, International Union of Crystallography

    Dr Petri Kursula

  62. Myelin

    Article • January 2003, Elsevier

    Dr Petri Kursula

  63. Myelin Disorders

    Article • January 2003, Elsevier

    Dr Petri Kursula

  64. Myelin Proteins

    Article • January 2003, Elsevier

    Dr Petri Kursula

  65. The Catalytic Cycle of Biosynthetic Thiolase:  A Conformational Journey of an Acetyl Group through Four Binding Modes and Two Oxyanion Holes

    Article • Biochemistry, December 2002, American Chemical Society (ACS)

    Dr Petri Kursula

  66. The current status of structural studies on proteins of the myelin sheath (Review)

    Article • International Journal of Molecular Medicine, November 2001, Spandidos Publications

    Dr Petri Kursula

  67. The small myelin-associated glycoprotein binds to tubulin and microtubules

    Article • Molecular Brain Research, February 2001, Elsevier

    Dr Petri Kursula

  68. S100β inhibits the phosphorylation of the L-MAG cytoplasmic domain by PKA

    Article • Molecular Brain Research, March 2000, Elsevier

    Dr Petri Kursula

  69. Estimation of total ribonucleic acid quantity from dilute samples by nondenaturing electrophoresis and silver staining

    Article • Electrophoresis, February 2000, Wiley

    Dr Petri Kursula

  70. Calcium‐Dependent Interaction Between the Large Myelin‐Associated Glycoprotein and S100β

    Article • Journal of Neurochemistry, October 1999, Wiley

    Dr Petri Kursula

  71. Expression of the amino acid dimorphism in the small myelin-associated glycoprotein cytoplasmic domain in rat peripheral nerves during postnatal development

    Article • Molecular Brain Research, March 1998, Elsevier

    Dr Petri Kursula

  72. 128 Amino acid dimorphism of the small myelin‐associated glycoprotein isoform in the peripheral nervous system

    Article • International Journal of Developmental Neuroscience, July 1996, Wiley

    Dr Petri Kursula