All Stories

  1. Fragmentation landscape of cell-free DNA revealed by deconvolutional analysis of end motifs

    Article • Proceedings of the National Academy of Sciences, April 2023, Proceedings of the National Academy of Sciences

    Prof Yuk Ming D Lo

  2. Epigenetic analysis of cell-free DNA by fragmentomic profiling

    Article • Proceedings of the National Academy of Sciences, October 2022, Proceedings of the National Academy of Sciences

    Prof Yuk Ming D Lo

  3. Fragmentomics of urinary cell-free DNA in nuclease knockout mouse models

    Article • PLoS Genetics, July 2022, PLOS

    Prof Yuk Ming D Lo

  4. Single-molecule sequencing reveals a large population of long cell-free DNA molecules in maternal plasma

    Article • Proceedings of the National Academy of Sciences, December 2021, Proceedings of the National Academy of Sciences

    Prof Yuk Ming D Lo

  5. Screening of Fetal Chromosomal Aneuploidy by Noninvasive Prenatal Testing: From Innovation to Setting Public Health Agendas to Potential Impact on Other Fields

    Article • Clinical Chemistry, October 2019, AACC

    Prof Yuk Ming D Lo

  6. Topologic Analysis of Plasma Mitochondrial DNA Reveals the Coexistence of Both Linear and Circular Molecules

    Article • Clinical Chemistry, July 2019, AACC

    Prof Yuk Ming D Lo

  7. Noninvasive Detection of Bladder Cancer by Shallow-Depth Genome-Wide Bisulfite Sequencing of Urinary Cell-Free DNA for Methylation and Copy Number Profiling

    Article • Clinical Chemistry, April 2019, AACC

    Prof Yuk Ming D Lo

  8. Noninvasive reconstruction of placental methylome from maternal plasma DNA: Potential for prenatal testing and monitoring

    Article • Prenatal Diagnosis, January 2018, Wiley

    Prof Yuk Ming D Lo

  9. DNase1 Does Not Appear to Play a Major Role in the Fragmentation of Plasma DNA in a Knockout Mouse Model

    Article • Clinical Chemistry, November 2017, AACC

    Prof Yuk Ming D Lo

  10. DNA of Erythroid Origin Is Present in Human Plasma and Informs the Types of Anemia

    Article • Clinical Chemistry, August 2017, AACC

    Prof Yuk Ming D Lo

  11. Single-Stranded DNA Library Preparation Preferentially Enriches Short Maternal DNA in Maternal Plasma

    Article • Clinical Chemistry, March 2017, AACC

    Prof Yuk Ming D Lo

  12. COFFEE: control-free noninvasive fetal chromosomal examination using maternal plasma DNA

    Article • Prenatal Diagnosis, February 2017, Wiley

    Prof Yuk Ming D Lo

  13. Gestational Age Assessment by Methylation and Size Profiling of Maternal Plasma DNA: A Feasibility Study

    Article • Clinical Chemistry, December 2016, AACC

    Prof Yuk Ming D Lo

  14. Combined Count- and Size-Based Analysis of Maternal Plasma DNA for Noninvasive Prenatal Detection of Fetal Subchromosomal Aberrations Facilitates Elucidation of the Fetal and/or Maternal Origin of the Aberrations

    Article • Clinical Chemistry, December 2016, AACC

    Prof Yuk Ming D Lo

  15. Universal Haplotype-Based Noninvasive Prenatal Testing for Single Gene Diseases

    Article • Clinical Chemistry, December 2016, AACC

    Prof Yuk Ming D Lo

  16. Theranos Session at the 2016 AACC Annual Scientific Meeting & Clinical Lab Expo: Expectations, Impressions, and Takeaways

    Article • The Journal of Applied Laboratory Medicine, October 2016, AACC

    Prof Yuk Ming D Lo, PETER WILDING

  17. Tracing the tissue of origin of plasma DNA-feasibility and implications

    Article • Annals of the New York Academy of Sciences, July 2016, Wiley

    Prof Yuk Ming D Lo

  18. Prenatal Diagnosis Innovation: Genome Sequencing of Maternal Plasma

    Article • Annual Review of Medicine, January 2016, Annual Reviews

    Prof Yuk Ming D Lo

  19. Noninvasive Prenatal Testing by Nanopore Sequencing of Maternal Plasma DNA: Feasibility Assessment

    Article • Clinical Chemistry, August 2015, AACC

    Prof Yuk Ming D Lo

  20. Disruptive Innovation in Laboratory Medicine

    Article • Clinical Chemistry, July 2015, AACC

    Prof Yuk Ming D Lo

  21. Non-invasive prenatal diagnosis by massively parallel sequencing of maternal plasma DNA

    Article • Open Biology, June 2012, Royal Society Publishing

    Prof Yuk Ming D Lo