All Stories

  1. Immune cell‐intrinsic Ah receptor facilitates the expression of antimicrobial REG3G in the small intestine

    Article • The FASEB Journal, February 2024, Wiley

    Dr Andrew Patterson

  2. Changes in fecal lipidome after treatment with ivacaftor without changes in microbiome or bile acids

    Article • Journal of Cystic Fibrosis, October 2023, Elsevier

    Dr Andrew Patterson

  3. Induction of AHR Signaling in Response to the Indolimine Class of Microbial Stress Metabolites

    Article • Metabolites, August 2023, MDPI AG

    Dr Andrew Patterson

  4. Accumulation of Linoleic Acid by Altered Peroxisome Proliferator-Activated Receptor-α Signaling Is Associated with Age-Dependent Hepatocarcinogenesis in Ppara Transgenic Mice

    Article • Metabolites, August 2023, MDPI AG

    Dr Andrew Patterson

  5. Molecular networking identifies an AHR-modulating benzothiazole from white button mushrooms (Agaricus bisporus)

    Article • Journal of Functional Foods, July 2023, Elsevier

    Dr Andrew Patterson

  6. Changes in the Type 2 diabetes gut mycobiome associate with metformin treatment across populations

    Article • May 2023, Cold Spring Harbor Laboratory Press

    Dr Andrew Patterson

  7. The Ah Receptor from Toxicity to Therapeutics: Report from the 5th AHR Meeting at Penn State University, USA, June 2022

    Article • International Journal of Molecular Sciences, March 2023, MDPI AG

    Dr Andrew Patterson

  8. Itaconate promotes the differentiation of murine stress erythroid progenitors by increasing Nrf2 activity

    Article • March 2023, Cold Spring Harbor Laboratory Press

    Dr Andrew Patterson

  9. Nitric oxide regulates metabolism in murine stress erythroid progenitors to promote recovery during inflammatory anemia

    Article • March 2023, Cold Spring Harbor Laboratory Press

    Dr Andrew Patterson

  10. Aryl hydrocarbon receptor activation affects nitrergic neuronal survival and delays intestinal motility in mice

    Article • Toxicological Sciences, February 2023, Oxford University Press (OUP)

    Dr Andrew Patterson

  11. Growth Hormone Alters Circulating Levels of Glycine and Hydroxyproline in Mice

    Article • Metabolites, January 2023, MDPI AG

    Dr Andrew Patterson

  12. Urine-based Detection of Congenital Portosystemic Shunt in C57BL/6 Mice

    Article • Function, January 2023, Oxford University Press (OUP)

    Dr Andrew Patterson

  13. Bile acids and the gut microbiota: metabolic interactions and impacts on disease

    Article • Nature Reviews Microbiology, October 2022, Springer Science + Business Media

    Dr Andrew Patterson

  14. Bile Acids Are Substrates for Amine N-Acyl Transferase Activity by Bile Salt Hydrolase

    Article • October 2022, Research Square

    Dr Andrew Patterson

  15. Early Life Polychlorinated Biphenyl 126 Exposure Disrupts Gut Microbiota and Metabolic Homeostasis in Mice Fed with High-Fat Diet in Adulthood

    Article • Metabolites, September 2022, MDPI AG

    Dr Andrew Patterson

  16. Early Life Short-Term Exposure to Polychlorinated Biphenyl 126 in Mice Leads to Metabolic Dysfunction and Microbiota Changes in Adulthood

    Article • International Journal of Molecular Sciences, July 2022, MDPI AG

    Dr Andrew Patterson

  17. Multi-Omics Strategies for Investigating the Microbiome in Toxicology Research

    Article • Toxicological Sciences, March 2022, Oxford University Press (OUP)

    Dr Andrew Patterson

  18. Defective humoral immunity disrupts bile acid homeostasis which promotes inflammatory disease of the small bowel

    Article • Nature Communications, January 2022, Springer Science + Business Media

    Dr Andrew Patterson

  19. A thermogenic fat-epithelium cell axis regulates intestinal disease tolerance

    Article • Proceedings of the National Academy of Sciences, November 2020, Proceedings of the National Academy of Sciences

    Dr Andrew Patterson

  20. Metabolic impact of persistent organic pollutants on gut microbiota

    Article • Gut Microbes, November 2020, Taylor & Francis

    Dr Andrew Patterson

  21. Differences in the gut microbiomes of distinct ethnicities within the same geographic area are linked to host metabolic health

    Article • October 2020, Cold Spring Harbor Laboratory Press

    Dr Andrew Patterson

  22. Impact of Facultative Bacteria on the Metabolic Function of an Obligate Insect-Bacterial Symbiosis

    Article • mBio, August 2020, ASM Journals

    Dr Andrew Patterson

  23. Intestinal microbiota-derived tryptophan metabolites are predictive of Ah receptor activity

    Article • Gut Microbes, August 2020, Taylor & Francis

    Dr Andrew Patterson

  24. Metabolic Profiling Reveals Aggravated Non-Alcoholic Steatohepatitis in High-Fat High-Cholesterol Diet-Fed Apolipoprotein E-Deficient Mice Lacking Ron Receptor Signaling

    Article • Metabolites, August 2020, MDPI AG

    Dr Andrew Patterson

  25. MDM2-Dependent Rewiring of Metabolomic and Lipidomic Profiles in Dedifferentiated Liposarcoma Models

    Article • Cancers, August 2020, MDPI AG

    Dr Andrew Patterson

  26. Ursodeoxycholic Acid (UDCA) Mitigates the Host Inflammatory Response during Clostridioides difficile Infection by Altering Gut Bile Acids

    Article • Infection and Immunity, May 2020, ASM Journals

    Dr Andrew Patterson

  27. Vancomycin prevents fermentable fiber-induced liver cancer in mice with dysbiotic gut microbiota

    Article • Gut Microbes, March 2020, Taylor & Francis

    Dr Andrew Patterson

  28. The microbiome modulating activity of bile acids

    Article • Gut Microbes, March 2020, Taylor & Francis

    Dr Andrew Patterson

  29. Perfluorooctane sulfonate alters gut microbiota-host metabolic homeostasis in mice

    Article • Toxicology, February 2020, Elsevier

    Dr Andrew Patterson

  30. Ursodeoxycholic acid (UDCA) mitigates the host inflammatory response duringClostridioides difficileinfection by altering gut bile acids which attenuates NF-κB signaling via bile acid activated receptors

    Article • January 2020, Cold Spring Harbor Laboratory Press

    Dr Andrew Patterson

  31. Metatranscriptomic Analysis of the Mouse Gut Microbiome Response to the Persistent Organic Pollutant 2,3,7,8-Tetrachlorodibenzofuran

    Article • Metabolites, December 2019, MDPI AG

    Dr Andrew Patterson

  32. The Human Transient Receptor Potential Melastatin 2 Ion Channel Modulates ROS Through Nrf2

    Article • Scientific Reports, October 2019, Springer Science + Business Media

    Dr Andrew Patterson

  33. Specialist and Generalist Fungal Parasites Induce Distinct Biochemical Changes in the Mandible Muscles of Their Host

    Article • International Journal of Molecular Sciences, September 2019, MDPI AG

    Dr Andrew Patterson

  34. Isolation and Identification of Aryl Hydrocarbon Receptor Modulators in White Button Mushrooms (Agaricus bisporus)

    Article • Journal of Agricultural and Food Chemistry, July 2019, American Chemical Society (ACS)

    Dr Andrew Patterson

  35. A Quantitative HILIC–MS/MS Assay of the Metabolic Response of Huh-7 Cells Exposed to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin

    Article • Metabolites, June 2019, MDPI AG

    Dr Andrew Patterson

  36. Interplay Between the Host, the Human Microbiome, and Drug Metabolism

    Article • Human Genomics, June 2019, Springer Science + Business Media

    Dr Andrew Patterson

  37. Microbiota Metabolism Promotes Synthesis of the Human Ah Receptor Agonist 2,8-Dihydroxyquinoline

    Article • Journal of Proteome Research, February 2019, American Chemical Society (ACS)

    Dr Andrew Patterson

  38. Berberine Directly Affects the Gut Microbiota to Promote Intestinal Farnesoid X Receptor Activation

    Article • Drug Metabolism and Disposition, November 2018, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Andrew Patterson

  39. Multiplatform Physiologic and Metabolic Phenotyping Reveals Microbial Toxicity

    Article • mSystems, November 2018, ASM Journals

    Dr Andrew Patterson

  40. Attenuation of Microbiotal Dysbiosis and Hypertension in a CRISPR/Cas9 Gene Ablation Rat Model of GPER1

    Article • Hypertension, November 2018, Wolters Kluwer Health

    Dr Andrew Patterson

  41. Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer

    Article • Cell, October 2018, Elsevier

    Dr Andrew Patterson

  42. Structural and Functional Analysis of the Gut Microbiome for Toxicologists

    Article • Current Protocols in Toxicology, September 2018, Wiley

    Dr Andrew Patterson

  43. Ron Receptor Signaling Ameliorates Hepatic Fibrosis in a Diet-Induced Nonalcoholic Steatohepatitis Mouse Model

    Article • Journal of Proteome Research, August 2018, American Chemical Society (ACS)

    Dr Andrew Patterson

  44. Molecular Regulation of Carcinogenesis: Friend and Foe

    Article • Toxicological Sciences, July 2018, Oxford University Press (OUP)

    Dr Andrew Patterson

  45. Regulation of vitamin D metabolism following disruption of the microbiota using broad spectrum antibiotics

    Article • The Journal of Nutritional Biochemistry, June 2018, Elsevier

    Dr Andrew Patterson

  46. Prebiotic effects of white button mushroom (Agaricus bisporus) feeding on succinate and intestinal gluconeogenesis in C57BL/6 mice

    Article • Journal of Functional Foods, June 2018, Elsevier

    Dr Andrew Patterson

  47. Intestine farnesoid X receptor agonist and the gut microbiota activate G‐protein bile acid receptor‐1 signaling to improve metabolism

    Article • Hepatology, May 2018, Wolters Kluwer Health

    Dr Andrew Patterson

  48. Vitamin A deficiency in mice alters host and gut microbial metabolism leading to altered energy homeostasis

    Article • The Journal of Nutritional Biochemistry, April 2018, Elsevier

    Dr Andrew Patterson

  49. Neuroprotective Role of the Ron Receptor Tyrosine Kinase Underlying Central Nervous System Inflammation in Health and Disease

    Article • Frontiers in Immunology, March 2018, Frontiers

    Dr Andrew Patterson

  50. Metabolomics Reveals Aryl Hydrocarbon Receptor Activation Induces Liver and Mammary Gland Metabolic Dysfunction in Lactating Mice

    Article • Journal of Proteome Research, March 2018, American Chemical Society (ACS)

    Dr Andrew Patterson

  51. The Gut Microbiota Regulates Endocrine Vitamin D Metabolism through Fibroblast Growth Factor 23

    Article • Frontiers in Immunology, March 2018, Frontiers

    Dr Andrew Patterson

  52. Lipid metabolism and lipophagy in cancer

    Article • Biochemical and Biophysical Research Communications, February 2018, Elsevier

    Dr Andrew Patterson

  53. Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota

    Article • Cell Metabolism, November 2017, Elsevier

    Dr Andrew Patterson

  54. Activation of intestinal hypoxia-inducible factor 2α during obesity contributes to hepatic steatosis

    Article • Nature Reports Stem Cells, October 2017, Nature

    Dr Andrew Patterson

  55. Dietary broccoli impacts microbial community structure and attenuates chemically induced colitis in mice in an Ah receptor dependent manner

    Article • Journal of Functional Foods, October 2017, Elsevier

    Dr Andrew Patterson

  56. Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota

    Article • Cell Metabolism, October 2017, Elsevier

    Dr Andrew Patterson

  57. Identification of a mouse Lactobacillus johnsonii strain with deconjugase activity against the FXR antagonist T-β-MCA

    Article • PLoS ONE, September 2017, PLOS

    Dr Andrew Patterson

  58. Orthogonal Comparison of GC–MS and 1H NMR Spectroscopy for Short Chain Fatty Acid Quantitation

    Article • Analytical Chemistry, July 2017, American Chemical Society (ACS)

    Dr Andrew Patterson

  59. Lipid Emulsion Added to a Liquid High-Carbohydrate Diet and Voluntary Running Exercise Reduce Lipogenesis and Ameliorate Early-Stage Hepatic Steatosis in Mice

    Article • Journal of Nutrition, March 2017, Oxford University Press (OUP)

    Dr Andrew Patterson

  60. Modulation of urinary siderophores by the diet, gut microbiota and inflammation in mice

    Article • The Journal of Nutritional Biochemistry, March 2017, Elsevier

    Dr Andrew Patterson

  61. The aryl hydrocarbon receptor as a moderator of host-microbiota communication

    Article • Current Opinion in Toxicology, February 2017, Elsevier

    Dr Andrew Patterson

  62. Intestinal Farnesoid X Receptor Signaling Modulates Metabolic Disease

    Article • Digestive Diseases, January 2017, Karger Publishers

    Dr Andrew Patterson

  63. An Intestinal Farnesoid X Receptor–Ceramide Signaling Axis Modulates Hepatic Gluconeogenesis in Mice

    Article • Diabetes, November 2016, American Diabetes Association

    Dr Andrew Patterson

  64. An Intestinal Microbiota–Farnesoid X Receptor Axis Modulates Metabolic Disease

    Article • Gastroenterology, November 2016, Elsevier

    Dr Andrew Patterson

  65. Omics Approaches To Probe Microbiota and Drug Metabolism Interactions

    Article • Chemical Research in Toxicology, October 2016, American Chemical Society (ACS)

    Dr Andrew Patterson

  66. Farnesoid X Receptor Signaling Shapes the Gut Microbiota and Controls Hepatic Lipid Metabolism

    Article • mSystems, October 2016, ASM Journals

    Dr Andrew Patterson

  67. Expression of the aryl hydrocarbon receptor contributes to the establishment of intestinal microbial community structure in mice

    Article • Scientific Reports, September 2016, Springer Science + Business Media

    Dr Andrew Patterson

  68. NMR-Based Metabolomics and Its Application in Drug Metabolism and Cancer Research

    Article • Current Pharmacology Reports, August 2016, Springer Science + Business Media

    Dr Andrew Patterson

  69. Metabolomics Reveals Altered Lipid Metabolism in a Mouse Model of Endometriosis

    Article • Journal of Proteome Research, August 2016, American Chemical Society (ACS)

    Dr Andrew Patterson

  70. Editor’s Highlight: Perfluorooctane Sulfonate-Choline Ion Pair Formation: A Potential Mechanism Modulating Hepatic Steatosis and Oxidative Stress in Mice

    Article • Toxicological Sciences, July 2016, Oxford University Press (OUP)

    Dr Andrew Patterson

  71. The Ron Receptor Tyrosine Kinase Regulates Macrophage Heterogeneity and Plays a Protective Role in Diet-Induced Obesity, Atherosclerosis, and Hepatosteatosis

    Article • The Journal of Immunology, May 2016, The American Association of Immunologists

    Dr Andrew Patterson

  72. Mass Spectrometry-Based Metabolomics Identifies Longitudinal Urinary Metabolite Profiles Predictive of Radiation-Induced Cancer

    Article • Cancer Research, February 2016, American Association for Cancer Research (AACR)

    Dr Andrew Patterson

  73. Antioxidant Drug Tempol Promotes Functional Metabolic Changes in the Gut Microbiota

    Article • Journal of Proteome Research, February 2016, American Chemical Society (ACS)

    Dr Andrew Patterson

  74. Impaired recovery from peritoneal inflammation in a mouse model of mild dietary zinc restriction

    Article • Molecular Nutrition & Food Research, February 2016, Wiley

    Dr Andrew Patterson

  75. Reversing methanogenesis to capture methane for liquid biofuel precursors

    Article • Microbial Cell Factories, January 2016, Springer Science + Business Media

    Dr Andrew Patterson

  76. Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction

    Article • Nature Communications, December 2015, Nature

    Dr Andrew Patterson

  77. Microbiota-Dependent Hepatic Lipogenesis Mediated by Stearoyl CoA Desaturase 1 (SCD1) Promotes Metabolic Syndrome in TLR5-Deficient Mice

    Article • Cell Metabolism, December 2015, Elsevier

    Dr Andrew Patterson

  78. Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles

    Article • Scientific Reports, August 2015, Nature

    Dr Andrew Patterson

  79. Lack of soluble fiber drives diet-induced adiposity in mice

    Article • AJP Gastrointestinal and Liver Physiology, July 2015, American Physiological Society

    Dr Andrew Patterson

  80. Metabolomics Reveals that Aryl Hydrocarbon Receptor Activation by Environmental Chemicals Induces Systemic Metabolic Dysfunction in Mice

    Article • Environmental Science & Technology, July 2015, American Chemical Society (ACS)

    Dr Andrew Patterson

  81. Role of fibroblast growth factor 21 in the early stage of NASH induced by methionine- and choline-deficient diet

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, July 2015, Elsevier

    Dr Andrew Patterson

  82. Inhibition of farnesoid X receptor signaling shows beneficial effects in human obesity

    Article • Journal of Hepatology, June 2015, Elsevier

    Dr Andrew Patterson

  83. Modulation of Colon Cancer by Nutmeg

    Article • Journal of Proteome Research, April 2015, American Chemical Society (ACS)

    Dr Andrew Patterson

  84. Persistent Organic Pollutants Modify Gut Microbiota–Host Metabolic Homeostasis in Mice Through Aryl Hydrocarbon Receptor Activation

    Article • Environmental Health Perspectives, March 2015, Environmental Health Perspectives

    Dr Andrew Patterson

  85. Kernel approaches for differential expression analysis of mass spectrometry-based metabolomics data

    Article • BMC Bioinformatics, March 2015, Springer Science + Business Media

    Dr Andrew Patterson

  86. Quantitative Analysis of Purine Nucleotides Indicates That Purinosomes Increase de Novo Purine Biosynthesis

    Article • Journal of Biological Chemistry, January 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Andrew Patterson

  87. Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease

    Article • Journal of Clinical Investigation, December 2014, American Society for Clinical Investigation

    Dr Andrew Patterson

  88. Aryl hydrocarbon receptor ligands in cancer: friend and foe

    Article • Nature Reviews Drug Discovery, November 2014, Nature

    Dr Andrew Patterson

  89. Microbial Determinants of Biochemical Individuality and Their Impact on Toxicology and Pharmacology

    Article • Cell Metabolism, November 2014, Elsevier

    Dr Andrew Patterson

  90. Crucial Role of Macrophage Selenoproteins in Experimental Colitis

    Article • The Journal of Immunology, September 2014, The American Association of Immunologists

    Dr Andrew Patterson

  91. Species-specific ant brain manipulation by a specialized fungal parasite

    Article • BMC Evolutionary Biology, August 2014, Springer Science + Business Media

    Dr Andrew Patterson

  92. Noninvasive Urinary Metabolomic Profiling Identifies Diagnostic and Prognostic Markers in Lung Cancer

    Article • Cancer Research, April 2014, American Association for Cancer Research (AACR)

    Dr Andrew Patterson

  93. Metabolomics

    Article • December 2013, Future Science

    Dr Andrew Patterson

  94. Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity

    Article • Nature Communications, September 2013, Nature

    Dr Andrew Patterson

  95. Metabolomics Reveals the Heterogeneous Secretome of Two Entomopathogenic Fungi to Ex Vivo Cultured Insect Tissues

    Article • PLoS ONE, August 2013, PLOS

    Dr Andrew Patterson

  96. Disruption of Thioredoxin Reductase 1 Protects Mice from Acute Acetaminophen-Induced Hepatotoxicity through Enhanced NRF2 Activity

    Article • Chemical Research in Toxicology, July 2013, American Chemical Society (ACS)

    Dr Andrew Patterson

  97. Metabolomics Reveals That Tumor Xenografts Induce Liver Dysfunction

    Article • Molecular & Cellular Proteomics, May 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Andrew Patterson

  98. Biochemistry and Physiology of the   Class Carbonic Anhydrase (Cpb) from Clostridium perfringens Strain 13

    Article • Journal of Bacteriology, March 2013, ASM Journals

    Dr Andrew Patterson, James Ferry

  99. Stable Isotope- and Mass Spectrometry-based Metabolomics as Tools in Drug Metabolism: A Study Expanding Tempol Pharmacology

    Article • Journal of Proteome Research, March 2013, American Chemical Society (ACS)

    Dr Andrew Patterson

  100. White Button Mushrooms Increase Microbial Diversity and Accelerate the Resolution of Citrobacter rodentium Infection in Mice

    Article • Journal of Nutrition, January 2013, American Society for Nutrition

    Dr Andrew Patterson

  101. Identification of serum insulin-like growth factor binding protein 1 as diagnostic biomarker for early-stage alcohol-induced liver disease

    Article • Journal of Translational Medicine, January 2013, Springer Science + Business Media

    Dr Andrew Patterson

  102. Network Analysis of a Pkd1-Mouse Model of Autosomal Dominant Polycystic Kidney Disease Identifies HNF4α as a Disease Modifier

    Article • PLoS Genetics, November 2012, PLOS

    Dr Andrew Patterson

  103. Metabolomics: An Essential Tool to Understand the Function of Peroxisome Proliferator-Activated Receptor Alpha

    Article • Toxicologic Pathology, November 2012, SAGE Publications

    Dr Andrew Patterson

  104. Metabolomics Identifies an Inflammatory Cascade Involved in Dioxin- and Diet-Induced Steatohepatitis

    Article • Cell Metabolism, November 2012, Elsevier

    Dr Andrew Patterson

  105. Radiation Metabolomics. 5. Identification of Urinary Biomarkers of Ionizing Radiation Exposure in Nonhuman Primates by Mass Spectrometry-Based Metabolomics

    Article • Radiation Research, October 2012, Radiation Research Society

    Dr Andrew Patterson

  106. Novel metabolites and roles for  -tocopherol in humans and mice discovered by mass spectrometry-based metabolomics

    Article • American Journal of Clinical Nutrition, September 2012, American Society for Nutrition

    Dr Andrew Patterson

  107. Role of the Ah Receptor in Homeostatic Control of Fatty Acid Synthesis in the Liver

    Article • Toxicological Sciences, June 2012, Oxford University Press (OUP)

    Dr Andrew Patterson

  108. Disruption of phospholipid and bile acid homeostasis in mice with nonalcoholic steatohepatitis

    Article • Hepatology, June 2012, Wiley

    Dr Andrew Patterson

  109. Peroxisome proliferator-activated receptor alpha induction of uncoupling protein 2 protects against acetaminophen-induced liver toxicity

    Article • Hepatology, June 2012, Wiley

    Dr Andrew Patterson

  110. Metabolomics reveals an essential role for peroxisome proliferator-activated receptor   in bile acid homeostasis

    Article • Journal of Lipid Research, June 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Andrew Patterson

  111. Aryl hydrocarbon receptor regulates the cholesterol biosynthetic pathway in a dioxin response element-independent manner

    Article • Hepatology, May 2012, Wiley

    Dr Andrew Patterson

  112. Abcb11 Deficiency Induces Cholestasis Coupled to Impaired  -Fatty Acid Oxidation in Mice

    Article • Journal of Biological Chemistry, May 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Andrew Patterson, Dr Peter Vogel

  113. Metabolomics reveals the metabolic map of procainamide in humans and mice

    Article • Biochemical Pharmacology, May 2012, Elsevier

    Dr Andrew Patterson

  114. Xenobiotic Metabolomics: Major Impact on the Metabolome

    Article • The Annual Review of Pharmacology and Toxicology, February 2012, Annual Reviews

    Dr Andrew Patterson

  115. Aberrant Lipid Metabolism in Hepatocellular Carcinoma Revealed by Plasma Metabolomics and Lipid Profiling

    Article • Cancer Research, September 2011, American Association for Cancer Research (AACR)

    Dr Andrew Patterson

  116. UPLC–MS-based Urine Metabolomics Reveals Indole-3-lactic Acid and Phenyllactic Acid as Conserved Biomarkers for Alcohol-induced Liver Disease in the Ppara -null Mouse Model

    Article • Journal of Proteome Research, September 2011, American Chemical Society (ACS)

    Dr Andrew Patterson

  117. A Cyp2a polymorphism predicts susceptibility to NNK-induced lung tumorigenesis in mice

    Article • Carcinogenesis, May 2011, Oxford University Press (OUP)

    Dr Andrew Patterson

  118. Metabolomics Reveals Attenuation of the SLC6A20 Kidney Transporter in Nonhuman Primate and Mouse Models of Type 2 Diabetes Mellitus

    Article • Journal of Biological Chemistry, April 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Andrew Patterson

  119. A comprehensive understanding of thioTEPA metabolism in the mouse using UPLC–ESI-QTOFMS-based metabolomics

    Article • Biochemical Pharmacology, April 2011, Elsevier

    Dr Andrew Patterson

  120. Lithocholic acid disrupts phospholipid and sphingolipid homeostasis leading to cholestasis in mice

    Article • Hepatology, April 2011, Wiley

    Dr Andrew Patterson

  121. Radiation Metabolomics. 4. UPLC-ESI-QTOFMS-Based Metabolomics for Urinary Biomarker Discovery in Gamma-Irradiated Rats

    Article • Radiation Research, April 2011, Radiation Research Society

    Dr Andrew Patterson

  122. PPAR action in insulin resistance unraveled by metabolomics: potential clinical implications

    Article • Genome Medicine, January 2011, Springer Science + Business Media

    Dr Andrew Patterson

  123. Metabolomics Identifies Novel Hnf1α-Dependent Physiological Pathwaysin Vivo

    Article • Molecular Endocrinology, December 2010, Endocrine Society

    Dr Andrew Patterson

  124. Comparative metabolism of cyclophosphamide and ifosfamide in the mouse using UPLC–ESI-QTOFMS-based metabolomics

    Article • Biochemical Pharmacology, October 2010, Elsevier

    Dr Andrew Patterson

  125. Identification of Noninvasive Biomarkers for Alcohol-Induced Liver Disease Using Urinary Metabolomics and the Ppara -null Mouse

    Article • Journal of Proteome Research, August 2010, American Chemical Society (ACS)

    Dr Andrew Patterson

  126. Xenobiotic Metabolism: A View through the Metabolometer

    Article • Chemical Research in Toxicology, May 2010, American Chemical Society (ACS)

    Dr Andrew Patterson

  127. Delineating the Role of Glutathione Peroxidase 4 in Protecting Cells Against Lipid Hydroperoxide Damage and in Alzheimer's Disease

    Article • Antioxidants & Redox Signaling, April 2010, Mary Ann Liebert Inc

    Dr Andrew Patterson

  128. Detection of radiation-exposure biomarkers by differential mobility prefiltered mass spectrometry (DMS–MS)

    Article • International Journal of Mass Spectrometry, April 2010, Elsevier

    Dr Andrew Patterson

  129. Human Urinary Metabolomic Profile of PPARα Induced Fatty Acid β-Oxidation

    Article • Journal of Proteome Research, September 2009, American Chemical Society (ACS)

    Dr Andrew Patterson

  130. Radiation Metabolomics. 3. Biomarker Discovery in the Urine of Gamma-Irradiated Rats Using a Simplified Metabolomics Protocol of Gas Chromatography-Mass Spectrometry Combined with Random Forests Machine Learning Algorithm

    Article • Radiation Research, August 2009, Radiation Research Society

    Dr Andrew Patterson

  131. Radiation Metabolomics. 2. Dose- and Time-Dependent Urinary Excretion of Deaminated Purines and Pyrimidines after Sublethal Gamma-Radiation Exposure in Mice

    Article • Radiation Research, July 2009, Radiation Research Society

    Dr Andrew Patterson

  132. Fenofibrate Metabolism in the Cynomolgus Monkey using Ultraperformance Liquid Chromatography-Quadrupole Time-of-Flight Mass Spectrometry-Based Metabolomics

    Article • Drug Metabolism and Disposition, February 2009, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Andrew Patterson

  133. The role of mass spectrometry-based metabolomics in medical countermeasures against radiation

    Article • Mass Spectrometry Reviews, January 2009, Wiley

    Dr Andrew Patterson

  134. Radiation Metabolomics. 1. Identification of Minimally Invasive Urine Biomarkers for Gamma-Radiation Exposure in Mice

    Article • Radiation Research, July 2008, Radiation Research Society

    Dr Andrew Patterson

  135. UPLC-ESI-TOFMS-Based Metabolomics and Gene Expression Dynamics Inspector Self-Organizing Metabolomic Maps as Tools for Understanding the Cellular Response to Ionizing Radiation

    Article • Analytical Chemistry, February 2008, American Chemical Society (ACS)

    Dr Andrew Patterson

  136. Targeting Thioredoxin Reductase 1 Reduction in Cancer Cells Inhibits Self-Sufficient Growth and DNA Replication

    Article • PLoS ONE, October 2007, PLOS

    Dr Andrew Patterson

  137. The Nuclear Export Signal of Splicing Factor Uap56p Interacts with Nuclear Pore-associated Protein Rae1p for mRNA Export in Schizosaccharomyces pombe

    Article • Journal of Biological Chemistry, April 2007, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Andrew Patterson

  138. Gadd34 Requirement for Normal Hemoglobin Synthesis

    Article • Molecular and Cellular Biology, March 2006, ASM Journals

    Dr Andrew Patterson

  139. Neural tube development requires the cooperation of p53- and Gadd45a-associated pathways

    Article • Birth Defects Research Part A Clinical and Molecular Teratology, January 2006, Wiley

    Dr Andrew Patterson

  140. Deletion ofXPCleads to lung tumors in mice and is associated with early events in human lung carcinogenesis

    Article • Proceedings of the National Academy of Sciences, September 2005, Proceedings of the National Academy of Sciences

    Dr Andrew Patterson

  141. Gadd45a acts as a modifier locus for lymphoblastic lymphoma

    Article • Leukemia, March 2005, Nature

    Dr Andrew Patterson

  142. Intra- and Intermolecular Domain Interactions of the C-terminal GTPase Effector Domain of the Multimeric Dynamin-like GTPase Drp1

    Article • Journal of Biological Chemistry, June 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Andrew Patterson