All Stories

  1. Common mechanisms of catalysis in small and heterotrimeric GTPases and their respective GAPs

    Article • Biological Chemistry, January 2017, De Gruyter

    PD Dr. Carsten Kötting, Klaus Gerwert

  2. Unraveling the Phosphocholination Mechanism of the Legionella pneumophila Enzyme AnkX

    Article • Biochemistry, August 2016, American Chemical Society (ACS)

    PD Dr. Carsten Kötting

  3. Catalysis of GTP Hydrolysis by Small GTPases at Atomic Detail by Integration of X-ray Crystallography, Experimental, and Theoretical IR Spectroscopy

    Article • Journal of Biological Chemistry, August 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    PD Dr. Carsten Kötting

  4. Label-Free Raman Spectroscopic Imaging Monitors the Integral Physiologically Relevant Drug Responses in Cancer Cells

    Article • Analytical Chemistry, July 2015, American Chemical Society (ACS)

    PD Dr. Carsten Kötting

  5. Chemical Functionalization of Germanium with Dextran Brushes for Immobilization of Proteins Revealed by Attenuated Total Reflection Fourier Transform Infrared Difference Spectroscopy

    Article • Analytical Chemistry, July 2015, American Chemical Society (ACS)

    PD Dr. Carsten Kötting

  6. Integration of Fourier Transform Infrared Spectroscopy, Fluorescence Spectroscopy, Steady-state Kinetics and Molecular Dynamics Simulations of Gα i1 Distinguishes between the GTP Hydrolysis and GDP Release Mechanism

    Article • Journal of Biological Chemistry, May 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    PD Dr. Carsten Kötting

  7. What vibrations tell us about GTPases

    Article • Biological Chemistry, January 2015, De Gruyter

    PD Dr. Carsten Kötting

  8. Immobilization of Proteins in their Physiological Active State at Functionalized Thiol Monolayers on ATR-Germanium Crystals

    Article • ChemBioChem, September 2014, Wiley

    PD Dr. Carsten Kötting

  9. A Modified Infrared Spectrometer with High Time Resolution and Its Application for Investigating Fast Conformational Changes of the GTPase Ras

    Article • Applied Spectroscopy, May 2014, SAGE Publications

    PD Dr. Carsten Kötting

  10. Automated Identification of Subcellular Organelles by Coherent Anti-Stokes Raman Scattering

    Article • Biophysical Journal, May 2014, Elsevier

    PD Dr. Carsten Kötting, Dr Sascha Daniel Krauß

  11. Label-free imaging of drug distribution and metabolism in colon cancer cells by Raman microscopy

    Article • The Analyst, January 2014, Royal Society of Chemistry

    PD Dr. Carsten Kötting

  12. Protein Immobilization on Chemically Functionalized Germanium Investigated by ATR-FTIR

    Article • Biophysical Journal, January 2014, Elsevier

    PD Dr. Carsten Kötting

  13. The dynamics of the catalytic site in small GTPases, variations on a common motif

    Article • FEBS Letters, May 2013, Wiley

    PD Dr. Carsten Kötting

  14. Spectral histopathology of colon cancer tissue sections by Raman imaging with 532 nm excitation provides label free annotation of lymphocytes, erythrocytes and proliferating nuclei of cancer cells

    Article • The Analyst, January 2013, Royal Society of Chemistry

    PD Dr. Carsten Kötting

  15. Monitoring Protein–Ligand Interactions by Time-Resolved FTIR Difference Spectroscopy

    Article • January 2013, Springer Science + Business Media

    PD Dr. Carsten Kötting

  16. Detailed Structure of the H 2 PO 4 – –Guanosine Diphosphate Intermediate in Ras-GAP Decoded from FTIR Experiments by Biomolecular Simulations

    Article • Journal of the American Chemical Society, December 2012, American Chemical Society (ACS)

    PD Dr. Carsten Kötting

  17. N-Ras Forms Dimers at POPC Membranes

    Article • Biophysical Journal, October 2012, Elsevier

    PD Dr. Carsten Kötting

  18. The Role of Magnesium for Geometry and Charge in GTP Hydrolysis, Revealed by Quantum Mechanics/Molecular Mechanics Simulations

    Article • Biophysical Journal, July 2012, Elsevier

    PD Dr. Carsten Kötting

  19. Surface-Attached Polyhistidine-Tag Proteins Characterized by FTIR Difference Spectroscopy

    Article • ChemPhysChem, June 2012, Wiley

    PD Dr. Carsten Kötting

  20. Time-resolved FTIR spectroscopy for monitoring protein dynamics exemplified by functional studies of Ras protein bound to a lipid bilayer

    Article • Chemical Physics, March 2012, Elsevier

    PD Dr. Carsten Kötting

  21. Heme oxygenases from Arabidopsis thaliana reveal different mechanisms of carbon monoxide binding

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, March 2012, Elsevier

    PD Dr. Carsten Kötting

  22. The specific vibrational modes of GTP in solution and bound to Ras: a detailed theoretical analysis by QM/MM simulations

    Article • Physical Chemistry Chemical Physics, January 2011, Royal Society of Chemistry

    PD Dr. Carsten Kötting

  23. Fourier Transform Infrared (FTIR) Spectroscopy

    Article • September 2010, Wiley

    PD Dr. Carsten Kötting

  24. Label-Free Screening of Drug–Protein Interactions by Time-Resolved Fourier Transform Infrared Spectroscopic Assays Exemplified by Ras Interactions

    Article • Applied Spectroscopy, September 2010, SAGE Publications

    PD Dr. Carsten Kötting

  25. Tyr39 of Ran Preserves the Ran·GTP Gradient by Inhibiting GTP Hydrolysis

    Article • Journal of Molecular Biology, August 2010, Elsevier

    PD Dr. Carsten Kötting

  26. Unravelling the mechanism of dual-specificity GAPs

    Article • The EMBO Journal, February 2010, Wiley

    PD Dr. Carsten Kötting, Begoña Sot

  27. Spectroscopic investigation of the reaction mechanism of CopB-B, the catalytic fragment from an archaeal thermophilic ATP-driven heavy metal transporter

    Article • FEBS Journal, September 2009, Wiley

    PD Dr. Carsten Kötting

  28. Secondary structure of lipidated Ras bound to a lipid bilayer

    Article • FEBS Journal, October 2008, Wiley

    PD Dr. Carsten Kötting

  29. Systematic approach to group-specific isotopic labeling of proteins for vibrational spectroscopy

    Article • Vibrational Spectroscopy, September 2008, Elsevier

    PD Dr. Carsten Kötting

  30. Surface Change of Ras Enabling Effector Binding Monitored in Real Time at Atomic Resolution

    Article • ChemBioChem, May 2007, Wiley

    PD Dr. Carsten Kötting

  31. Cover Picture: Surface Change of Ras Enabling Effector Binding Monitored in Real Time at Atomic Resolution (ChemBioChem 7/2007)

    Article • ChemBioChem, May 2007, Wiley

    PD Dr. Carsten Kötting

  32. Insight into Catalysis of a Unique GTPase Reaction by a Combined Biochemical and FTIR Approach

    Article • Journal of Molecular Biology, April 2007, Elsevier

    PD Dr. Carsten Kötting

  33. Proteinreaktionen: aufgelöst mit trFTIR

    Article • Nachrichten aus der Chemie, October 2006, Wiley

    PD Dr. Carsten Kötting

  34. Proteins in Action Monitored by Time-Resolved FTIR Spectroscopy

    Article • ChemPhysChem, April 2005, Wiley

    PD Dr. Carsten Kötting

  35. Time-resolved FTIR studies provide activation free energy, activation enthalpy and activation entropy for GTPase reactions

    Article • Chemical Physics, December 2004, Elsevier

    PD Dr. Carsten Kötting

  36. IR Spectra of Phosphate Ions in Aqueous Solution:  Predictions of a DFT/MM Approach Compared with Observations

    Article • The Journal of Physical Chemistry A, July 2004, American Chemical Society (ACS)

    PD Dr. Carsten Kötting

  37. Dynamics of Molecules near Ionization

    Article • The Journal of Physical Chemistry A, December 2003, American Chemical Society (ACS)

    PD Dr. Carsten Kötting

  38. Coherent Dynamics in Complex Elimination Reactions:  Experimental and Theoretical Femtochemistry of 1,3-Dibromopropane and Related Systems † , ‡

    Article • The Journal of Physical Chemistry A, August 2002, American Chemical Society (ACS)

    PD Dr. Carsten Kötting

  39. Femtochemistry of Norrish Type-I Reactions: III. Highly Excited Ketones—Theoretical

    Article • ChemPhysChem, January 2002, Wiley

    PD Dr. Carsten Kötting

  40. Cover Picture

    Article • ChemPhysChem, May 2001, Wiley

    PD Dr. Carsten Kötting

  41. Cover Picture

    Article • ChemPhysChem, May 2001, Wiley

    PD Dr. Carsten Kötting

  42. Femtochemistry of Norrish Type-I Reactions: II. The Anomalous Predissociation Dynamics of Cyclobutanone on the S1 Surface

    Article • ChemPhysChem, May 2001, Wiley

    PD Dr. Carsten Kötting

  43. Femtochemistry of Norrish Type-I Reactions: I. Experimental and Theoretical Studies of Acetone and Related Ketones on the S1 Surface

    Article • ChemPhysChem, May 2001, Wiley

    PD Dr. Carsten Kötting

  44. Femtochemistry of Norrish Type-I Reactions: I. Experimental and Theoretical Studies of Acetone and Related Ketones on the S1 Surface

    Article • ChemPhysChem, May 2001, Wiley

    PD Dr. Carsten Kötting

  45. Femtochemistry of Norrish Type-I Reactions: II. The Anomalous Predissociation Dynamics of Cyclobutanone on the S1 Surface

    Article • ChemPhysChem, May 2001, Wiley

    PD Dr. Carsten Kötting

  46. Super‐electrophilic carbenes and the concept of Philicity

    Article • Journal of Physical Organic Chemistry, October 2000, Wiley

    PD Dr. Carsten Kötting

  47. Difluorosilanethione F2Si=S by Flash Vacuum Thermolysis of (F3Si)2S and by Reaction of SiS with F2 – Matrix Studies and Ab initio Calculations

    Article • European Journal of Inorganic Chemistry, November 1999, Wiley

    PD Dr. Carsten Kötting

  48. Difluorosilanethione F2Si=S by Flash Vacuum Thermolysis of (F3Si)2S and by Reaction of SiS with F2 – Matrix Studies and Ab initio Calculations

    Article • European Journal of Inorganic Chemistry, November 1999, Wiley

    PD Dr. Carsten Kötting

  49. Insertion of Difluorovinylidene into Hydrogen and Methane

    Article • Journal of the American Chemical Society, September 1999, American Chemical Society (ACS)

    PD Dr. Carsten Kötting

  50. Reactions of Difluorovinylidene—A Super-Electrophilic Carbene

    Article • Chemistry - A European Journal, January 1999, Wiley

    PD Dr. Carsten Kötting

  51. Evidence for the Non-Concerted Addition of Difluorovinylidene to Acetylenes

    Article • Chemistry - A European Journal, November 1998, Wiley

    PD Dr. Carsten Kötting

  52. Evidence for the Non-Concerted Addition of Difluorovinylidene to Acetylenes

    Article • Chemistry - A European Journal, November 1998, Wiley

    PD Dr. Carsten Kötting

  53. Oxidation of Difluorovinylidene

    Article • Chemistry - A European Journal, September 1998, Wiley

    PD Dr. Carsten Kötting

  54. Matrix Isolation of 3,4-Benzocyclodeca-3,7,9-triene-1,5-diyne

    Article • European Journal of Organic Chemistry, May 1998, Wiley

    PD Dr. Carsten Kötting

  55. A Charge-Transfer Complex of Xenon and Difluorovinylidene

    Article • Journal of the American Chemical Society, January 1998, American Chemical Society (ACS)

    PD Dr. Carsten Kötting

  56. Difluorovinylidene, F2CC:

    Article • Angewandte Chemie International Edition in English, October 1997, Wiley

    PD Dr. Carsten Kötting

  57. Difluorvinyliden, F2CC:

    Article • Angewandte Chemie, September 1997, Wiley

    PD Dr. Carsten Kötting

  58. Monitoring Protein–Ligand Interactions by Time-Resolved FTIR Difference Spectroscopy

    Article • Springer Science + Business Media

    PD Dr. Carsten Kötting