All Stories

  1. Malonyl-CoA Accumulation as a Compensatory Cytoprotective Mechanism in Cardiac Cells in Response to 7-Ketocholesterol-Induced Growth Retardation

    Article • International Journal of Molecular Sciences, February 2023, MDPI AG

    Gigin Lin

  2. Glycolytic Plasticity of Metastatic Lung Cancer Captured by Noninvasive 18F-FDG PET/CT and Serum 1H-NMR Analysis: An Orthotopic Murine Model Study

    Article • Metabolites, January 2023, MDPI AG

    Gigin Lin

  3. Response to Brigatinib Targeted Therapy in Non-Small Cell Lung Cancer Harboring Epidermal Growth Factor Receptor Exon 19 Deletion, T790M, and cis-C797S Triple Mutations: A Case Report

    Article • International Journal of Molecular Sciences, December 2022, MDPI AG

    Gigin Lin

  4. MRI Radiomics for Predicting Survival in Patients with Locally Advanced Hypopharyngeal Cancer Treated with Concurrent Chemoradiotherapy

    Article • Cancers, December 2022, MDPI AG

    Gigin Lin

  5. Metabolomic Signature of Diabetic Kidney Disease in Cerebrospinal Fluid and Plasma of Patients with Type 2 Diabetes Using Liquid Chromatography-Mass Spectrometry

    Article • Diagnostics, October 2022, MDPI AG

    Gigin Lin

  6. Enteroviral 2B Interacts with VDAC3 to Regulate Reactive Oxygen Species Generation That Is Essential to Viral Replication

    Article • Viruses, August 2022, MDPI AG

    Gigin Lin

  7. Developing a Method to Estimate the Downstream Metabolite Signals from Hyperpolarized [1-13C]Pyruvate

    Article • Sensors, July 2022, MDPI AG

    Gigin Lin

  8. Uterine fibroid-like tumors: spectrum of MR imaging findings and their differential diagnosis

    Article • Abdominal Radiology, March 2022, Springer Science + Business Media

    Gigin Lin

  9. Magnetic Resonance-Based Synthetic Computed Tomography Using Generative Adversarial Networks for Intracranial Tumor Radiotherapy Treatment Planning

    Article • Journal of Personalized Medicine, February 2022, MDPI AG

    Gigin Lin

  10. Diagnostic Accuracy of Whole-Body Computed Tomography for Incidental Ovarian Tumors in Patients with Prior Breast Cancer

    Article • Diagnostics, January 2022, MDPI AG

    Gigin Lin

  11. Clinical impact of a deep learning system for automated detection of missed pulmonary nodules on routine body computed tomography including the chest region

    Article • European Radiology, January 2022, Springer Science + Business Media

    Gigin Lin

  12. Optimizing risk-based breast cancer screening policies with reinforcement learning

    Article • Nature Reports Stem Cells, January 2022, Springer Science + Business Media

    Gigin Lin

  13. Measuring Heterogeneity in 18F-Fluorodeoxyglucose Positron Emission Tomography Images for Classifying Metastatic and Benign Bone Lesions in Patients with Cervical Cancer

    Article • Journal of Medical and Biological Engineering, December 2021, Springer Science + Business Media

    Gigin Lin

  14. Multi-Institutional Validation of a Mammography-Based Breast Cancer Risk Model

    Article • Journal of Clinical Oncology, November 2021, American Society of Clinical Oncology (ASCO)

    Gigin Lin

  15. Prostate-specific membrane antigen (PSMA) fusion imaging in prostate cancer: PET/CT vs PET/MRI

    Article • British Journal of Radiology, November 2021, British Institute of Radiology

    Gigin Lin

  16. Automatic Segmentation of Pelvic Cancers Using Deep Learning: State-of-the-Art Approaches and Challenges

    Article • Diagnostics, October 2021, MDPI AG

    Gigin Lin

  17. Magnetic Resonance Spectroscopy for Risk Stratification of Sonographically Indeterminate Ovarian Neoplasms: Preliminary Study

    Article • Diagnostics, October 2021, MDPI AG

    Gigin Lin

  18. Automatic Segmentation of Pelvic Cancers using Deep Learning: State-of-the-Art Approaches and Challenges

    Article • August 2021, MDPI AG

    Gigin Lin

  19. Monitoring Early Glycolytic Flux Alterations Following Radiotherapy in Cancer and Immune Cells: Hyperpolarized Carbon-13 Magnetic Resonance Imaging Study

    Article • Metabolites, August 2021, MDPI AG

    Gigin Lin

  20. Optimizing risk-based breast cancer screening policies with reinforcement learning

    Article • June 2021, Research Square

    Gigin Lin

  21. Radiation-Induced Metabolic Shifts in the Hepatic Parenchyma: Findings from 18F-FDG PET Imaging and Tissue NMR Metabolomics in a Mouse Model for Hepatocellular Carcinoma

    Article • Molecules, April 2021, MDPI AG

    Gigin Lin

  22. Risk of nephrogenic systemic fibrosis in patients with impaired renal function undergoing fixed-dose gadoxetic acid-enhanced magnetic resonance imaging

    Article • Abdominal Radiology, March 2021, Springer Science + Business Media

    Gigin Lin

  23. Computer-Aided Segmentation and Machine Learning of Integrated Clinical and Diffusion-Weighted Imaging Parameters for Predicting Lymph Node Metastasis in Endometrial Cancer

    Article • Cancers, March 2021, MDPI AG

    Gigin Lin

  24. Toward robust mammography-based models for breast cancer risk

    Article • Science Translational Medicine, January 2021, American Association for the Advancement of Science

    Gigin Lin

  25. Simple Stepwise Approach to Differentiate Cyst-Like Soft-Tissue Masses by Using Time-Resolved Magnetic Resonance Angiography

    Article • Diagnostics, December 2020, MDPI AG

    Gigin Lin

  26. Radiation-induced Metabolic Shifts in the Hepatic Parenchyma: Findings from 18F-FDG PET Imaging and Tissue NMR Metabolomics in a Mouse Model for Hepatocellular Carcinoma

    Article • November 2020, Research Square

    Gigin Lin

  27. Nuclear Magnetic Resonance Metabolomics Biomarkers for Identifying High Risk Patients with Extranodal Extension in Oral Squamous Cell Carcinoma

    Article • Journal of Clinical Medicine, March 2020, MDPI AG

    Gigin Lin

  28. Metabolomic Analysis Reveals Distinct Profiles in the Plasma and Urine Associated with IgE Reactions in Childhood Asthma

    Article • Journal of Clinical Medicine, March 2020, MDPI AG

    Gigin Lin

  29. Left Ventricular Function and Myocardial Triglyceride Content on 3T Cardiac MR Predict Major Cardiovascular Adverse Events and Readmission in Patients Hospitalized with Acute Heart Failure

    Article • Journal of Clinical Medicine, January 2020, MDPI AG

    Gigin Lin

  30. Response evaluation for immunotherapy through semi-automatic software based on RECIST 1.1, irRC, and iRECIST criteria: comparison with subjective assessment

    Article • Acta Radiologica, November 2019, SAGE Publications

    Gigin Lin

  31. De novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy

    Article • Autophagy, September 2019, Taylor & Francis

    Gigin Lin, Professor Martin O Leach

  32. Utility of diffusion-weighted and contrast-enhanced magnetic resonance imaging in diagnosing and differentiating between high- and low-grade uterine endometrial stromal sarcoma

    Article • Cancer Imaging, September 2019, Springer Science + Business Media

    Gigin Lin

  33. 1H Nuclear Magnetic Resonance (NMR)-Based Cerebrospinal Fluid and Plasma Metabolomic Analysis in Type 2 Diabetic Patients and Risk Prediction for Diabetic Microangiopathy

    Article • Journal of Clinical Medicine, June 2019, MDPI AG

    Gigin Lin

  34. Acute Tumor Transition Angle on Computed Tomography Predicts Chromosomal Instability Status of Primary Gastric Cancer: Radiogenomics Analysis from TCGA and Independent Validation

    Article • Cancers, May 2019, MDPI AG

    Gigin Lin

  35. Glycerophospholipids pathways and chromosomal instability in gastric cancer: Global lipidomics analysis

    Article • World Journal of Gastrointestinal Oncology, March 2019, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Gigin Lin

  36. Metabolomics Reveals Anaerobic Bacterial Fermentation and Hypoxanthine Accumulation for Fibrinous Pleural Effusions in Children with Pneumonia

    Article • Journal of Proteome Research, February 2019, American Chemical Society (ACS)

    Gigin Lin

  37. Detecting recurrent ovarian cancer: revisit the values of whole-body CT and serum CA 125 levels

    Article • Acta Radiologica, January 2019, SAGE Publications

    Gigin Lin

  38. Current Status of Magnetic Resonance Imaging in Patients with Malignant Uterine Neoplasms: A Review

    Article • Korean Journal of Radiology, January 2019, The Korean Society of Radiology (KAMJE)

    Gigin Lin

  39. Metabolomic alterations and chromosomal instability status in gastric cancer

    Article • World Journal of Gastroenterology, September 2018, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Gigin Lin

  40. Prognostic model based on magnetic resonance imaging, whole-tumour apparent diffusion coefficient values and HPV genotyping for stage IB-IV cervical cancer patients following chemoradiotherapy

    Article • European Radiology, July 2018, Springer Science + Business Media

    Gigin Lin

  41. Early Imaging Biomarker of Myocardial Glucose Adaptations in High-Fat-Diet-Induced Insulin Resistance Model by Using 18F-FDG PET and [U-13C]glucose Nuclear Magnetic Resonance Tracer

    Article • Contrast Media & Molecular Imaging, July 2018, Hindawi Publishing Corporation

    Gigin Lin, Shao-Chieh Chiu

  42. Recurrence after fertility-preserving surgery for low-grade endometrial stromal sarcoma

    Article • Journal of Obstetrics and Gynaecology Research, July 2018, Wiley

    Gigin Lin

  43. Presurgical Identification of Uterine Smooth Muscle Malignancies through the Characteristic FDG Uptake Pattern on PET Scans

    Article • Contrast Media & Molecular Imaging, June 2018, Hindawi Publishing Corporation

    Gigin Lin

  44. Urinary metabolomic profiling reveals metabolites for asthma development in early childhood

    Article • Pediatric Allergy and Immunology, June 2018, Wiley

    Jing-Long Huang , Chih-Yung Chiu, Gigin Lin

  45. Synergistic antiproliferative effects of an mTOR inhibitor (rad001) plus gemcitabine on cholangiocarcinoma by decreasing choline kinase activity

    Article • Disease Models & Mechanisms, April 2018, The Company of Biologists

    Gigin Lin

  46. Emerging Molecular Imaging Techniques in Gynecologic Oncology

    Article • PET Clinics, April 2018, Elsevier

    Gigin Lin

  47. Quantitative analysis of enhanced malignant and benign lesions on contrast-enhanced spectral mammography

    Article • British Journal of Radiology, February 2018, British Institute of Radiology

    Gigin Lin

  48. Diagnostic accuracy of 3.0T diffusion-weighted MRI for patients with uterine carcinosarcoma: Assessment of tumor extent and lymphatic metastasis

    Article • Journal of Magnetic Resonance Imaging, February 2018, Wiley

    Gigin Lin

  49. Glycerophospholipids and sphingolipids correlate with poor prognostic genotypes of human papillomavirus in cervical cancer: global lipidomics analysis

    Article • Analytical Methods, January 2018, Royal Society of Chemistry

    Gigin Lin

  50. Predictive value of 1H MR spectroscopy and 18F-FDG PET/CT for local control of advanced oropharyngeal and hypopharyngeal squamous cell carcinoma receiving chemoradiotherapy: a prospective study

    Article • Oncotarget, December 2017, Impact Journals, LLC

    Gigin Lin

  51. Developing and validating a multivariable prediction model to improve the diagnostic accuracy in determination of cervical versus endometrial origin of uterine adenocarcinomas: A prospective MR study combining diffusion-weighted imaging and spectroscopy

    Article • Journal of Magnetic Resonance Imaging, November 2017, Wiley

    Gigin Lin

  52. Comparison of positron emission tomography/computed tomography and magnetic resonance imaging for posttherapy evaluation in patients with advanced cervical cancer receiving definitive concurrent chemoradiotherapy

    Article • European Journal of Nuclear Medicine and Molecular Imaging, November 2017, Springer Science + Business Media

    Gigin Lin

  53. Early Response Monitoring Following Radiation Therapy by Using [18F]FDG and [11C]Acetate PET in Prostate Cancer Xenograft Model with Metabolomics Corroboration

    Article • Molecules, November 2017, MDPI AG

    Gigin Lin

  54. Nicotinamide nucleotide transhydrogenase (NNT) deficiency dysregulates mitochondrial retrograde signaling and impedes proliferation

    Article • Redox Biology, August 2017, Elsevier

    Gigin Lin

  55. Phase I Dose-Escalation Study of Weekly Paclitaxel and Cisplatin Followed by Radical Hysterectomy in Stages IB2 and IIA2 Cervical Cancer

    Article • American Journal of Clinical Oncology, June 2017, Wolters Kluwer Health

    Gigin Lin

  56. Massively parallel sequencing and genome-wide copy number analysis revealed a clonal relationship in benign metastasizing leiomyoma

    Article • Oncotarget, May 2017, Impact Journals, LLC

    Gigin Lin

  57. Diffusion radiomics analysis of intratumoral heterogeneity in a murine prostate cancer model following radiotherapy: Pixelwise correlation with histology

    Article • Journal of Magnetic Resonance Imaging, February 2017, Wiley

    Gigin Lin

  58. Positron emission tomography in the management of documented or suspected recurrent ovarian cancer

    Article • Journal of the Formosan Medical Association, January 2017, Elsevier

    Gigin Lin

  59. Cancer Metabolism and Tumor Heterogeneity: Imaging Perspectives Using MR Imaging and Spectroscopy

    Article • Contrast Media & Molecular Imaging, January 2017, Hindawi Publishing Corporation

    Gigin Lin

  60. Ulnar arterial epithelioid hemangioma: A unique demonstration using time-resolved MR angiography

    Article • International Journal of Cardiology, November 2016, Elsevier

    Gigin Lin

  61. Laparoscopic vision of giant hepatic hemangioma

    Article • Gynecology and Minimally Invasive Therapy, November 2016, Elsevier

    Gigin Lin

  62. Endometrial cancer with cervical stromal invasion: diagnostic accuracy of diffusion-weighted and dynamic contrast enhanced MR imaging at 3T

    Article • European Radiology, September 2016, Springer Science + Business Media

    Gigin Lin

  63. Metabolomic analysis of infectious parapneumonic effusions reveals biomarkers for management of children withstreptococcus pneumoniaepneumonia

    Article • European Respiratory Journal, September 2016, European Respiratory Society (ERS)

    Gigin Lin

  64. 1H MR spectroscopy in cervical carcinoma using external phase array body coil at 3.0 Tesla: Prediction of poor prognostic human papillomavirus genotypes

    Article • Journal of Magnetic Resonance Imaging, July 2016, Wiley

    Gigin Lin

  65. Utility of 18F-FDG PET/CT in patients with advanced squamous cell carcinoma of the uterine cervix receiving concurrent chemoradiotherapy: a parallel study of a prospective randomized trial

    Article • European Journal of Nuclear Medicine and Molecular Imaging, May 2016, Springer Science + Business Media

    Gigin Lin

  66. Metabolomic Profiling of Infectious Parapneumonic Effusions Reveals Biomarkers for Guiding Management of Children with Streptococcus pneumoniae Pneumonia

    Article • Scientific Reports, April 2016, Nature

    Gigin Lin

  67. Metabolomics Reveals Dynamic Metabolic Changes Associated with Age in Early Childhood

    Article • PLoS ONE, February 2016, PLOS

    Gigin Lin

  68. Abstract B56: Treatment-induced autophagy increases amino acid uptake and switches glucose addiction to amino acid catabolism in cancer

    Article • Molecular Cancer Research, January 2016, American Association for Cancer Research (AACR)

    Gigin Lin

  69. Quantitative susceptibility map from the patients with chronic heart failure

    Article • Journal of Cardiovascular Magnetic Resonance, January 2016, Springer Science + Business Media

    Gigin Lin

  70. Myocardial triglyceride content at 3 T cardiovascular magnetic resonance and left ventricular systolic function: a cross-sectional study in patients hospitalized with acute heart failure

    Article • Journal of Cardiovascular Magnetic Resonance, December 2015, Springer Science + Business Media

    Gigin Lin

  71. Influence of menopausal status on diagnostic accuracy of myometrial invasion in endometrial cancer: diffusion-weighted and dynamic contrast-enhanced MRI at 3 T

    Article • Clinical Radiology, November 2015, Elsevier

    Gigin Lin

  72. 18F-FDG PET in small-cell cervical cancer: a prospective study with long-term follow-up

    Article • European Journal of Nuclear Medicine and Molecular Imaging, October 2015, Springer Science + Business Media

    Gigin Lin

  73. Comparison of the diagnostic accuracy of contrast-enhanced MRI and diffusion-weighted MRI in the differentiation between uterine leiomyosarcoma / smooth muscle tumor with uncertain malignant potential and benign leiomyoma

    Article • Journal of Magnetic Resonance Imaging, September 2015, Wiley

    Gigin Lin

  74. Abstract 2897: Phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy

    Article • Cancer Research, August 2015, American Association for Cancer Research (AACR)

    Gigin Lin

  75. Computed tomography, magnetic resonance imaging and FDG positron emission tomography in the management of vulvar malignancies

    Article • European Radiology, December 2014, Springer Science + Business Media

    Gigin Lin

  76. Molecular imaging in the management of gynecologic malignancies

    Article • Gynecologic Oncology, October 2014, Elsevier

    Gigin Lin

  77. Dichloroacetate induces autophagy in colorectal cancer cells and tumours

    Article • British Journal of Cancer, June 2014, Nature

    Gigin Lin, Professor Martin O Leach

  78. Treatment Failure in Endometrial Carcinoma

    Article • International Journal of Gynecological Cancer, June 2014, Wolters Kluwer Health

    Gigin Lin

  79. Reduced Warburg Effect in Cancer Cells Undergoing Autophagy: Steady- State 1H-MRS and Real-Time Hyperpolarized 13C-MRS Studies

    Article • PLoS ONE, March 2014, PLOS

    Gigin Lin

  80. Current Opportunities and Challenges of Magnetic Resonance Spectroscopy, Positron Emission Tomography, and Mass Spectrometry Imaging for Mapping Cancer MetabolismIn Vivo

    Article • BioMed Research International, January 2014, Hindawi Publishing Corporation

    Gigin Lin

  81. Identification of prognostic factors in patients with cervical cancer and supraclavicular lymph node recurrence

    Article • Gynecologic Oncology, November 2011, Elsevier

    Gigin Lin

  82. Comparison of ultrasonographically guided fine-needle aspiration and core needle biopsy in the diagnosis of parotid masses

    Article • Journal of Clinical Ultrasound, September 2011, Wiley

    Gigin Lin

  83. Abstract 3788: Autophagy induced by DCA, PI3K inhibition or starvation results in reduced lactate production measured in real-time by DNP 13C MRS

    Article • Cancer Research, April 2011, American Association for Cancer Research (AACR)

    Gigin Lin

  84. Adequacy and complications of computed tomography-guided core needle biopsy on non-small cell lung cancers for epidermal growth factor receptor mutations demonstration: 18-gauge or 20-gauge biopsy needle

    Article • Lung Cancer, February 2010, Elsevier

    Gigin Lin

  85. An Integrated Diffusion Map for the Analysis of Diffusion Properties

    Article • Academic Radiology, April 2009, Elsevier

    Gigin Lin

  86. Myometrial Invasion in Endometrial Cancer: Diagnostic Accuracy of Diffusion-weighted 3.0-T MR Imaging—Initial Experience

    Article • Radiology, March 2009, Radiological Society of North America (RSNA)

    Gigin Lin

  87. Transurethral partial cystectomy and laparoscopic reconstruction for the management of bladder endometriosis

    Article • Fertility and Sterility, November 2008, Elsevier

    Gigin Lin

  88. Computed tomography-guided core-needle biopsy specimens demonstrate epidermal growth factor receptor mutations in patients with non-small-cell lung cancer

    Article • Acta Radiologica, November 2008, SAGE Publications

    Gigin Lin

  89. Correlation of apparent diffusion coefficients measured by 3T diffusion-weighted MRI and SUV from FDG PET/CT in primary cervical cancer

    Article • European Journal of Nuclear Medicine and Molecular Imaging, September 2008, Springer Science + Business Media

    Gigin Lin

  90. Positron emission tomography in evaluating the feasibility of curative intent in cervical cancer patients with limited distant lymph node metastases

    Article • Gynecologic Oncology, August 2008, Elsevier

    Gigin Lin

  91. Detection of lymph node metastasis in cervical and uterine cancers by diffusion-weighted magnetic resonance imaging at 3T

    Article • Journal of Magnetic Resonance Imaging, July 2008, Wiley

    Gigin Lin

  92. 18F-fluorodeoxyglucose positron emission tomography in uterine carcinosarcoma

    Article • European Journal of Nuclear Medicine and Molecular Imaging, October 2007, Springer Science + Business Media

    Gigin Lin

  93. Combined hepatocellular cholangiocarcinoma: prognostic factors investigated by computed tomography/magnetic resonance imaging

    Article • International Journal of Clinical Practice, May 2007, Wiley

    Gigin Lin

  94. Transcutaneous arterial embolization to control massive tumor bleeding in head and neck cancer: 63 patients’ experiences from a single medical center

    Article • Supportive Care in Cancer, March 2007, Springer Science + Business Media

    Gigin Lin