All Stories

  1. Heterozygous loss of Rbm24 in the adult mouse heart increases sarcomere slack length but does not affect function

    Article • Scientific Reports, May 2020, Springer Science + Business Media

    Dr Abdelaziz Beqqali

  2. Alternative splicing in cardiomyopathy

    Article • Biophysical Reviews, July 2018, Springer Science + Business Media

    Dr Abdelaziz Beqqali

  3. The clinical outcome of LMNA missense mutations can be associated with the amount of mutated protein in the nuclear envelope

    Article • European Journal of Heart Failure, June 2018, Wiley

    Dr Abdelaziz Beqqali

  4. RBM20 Mutations Induce an Arrhythmogenic Dilated Cardiomyopathy Related to Disturbed Calcium Handling

    Article • Circulation, April 2018, Wolters Kluwer Health

    Dr Abdelaziz Beqqali

  5. The MEF2 transcriptional target DMPK induces loss of sarcomere structure and cardiomyopathy

    Article • Cardiovascular Research, April 2018, Oxford University Press (OUP)

    Dr Abdelaziz Beqqali

  6. Cardiac circRNAs arise mainly from constitutive exons rather than alternatively spliced exons

    Article • RNA, March 2018, Cold Spring Harbor Laboratory Press

    Dr Abdelaziz Beqqali

  7. Z-disc protein CHAPb induces cardiomyopathy and contractile dysfunction in the postnatal heart

    Article • PLoS ONE, December 2017, PLOS

    Dr Abdelaziz Beqqali

  8. The RNA-binding protein Rbm38 is dispensable during pressure overload-induced cardiac remodeling in mice

    Article • PLoS ONE, August 2017, PLOS

    Dr Abdelaziz Beqqali

  9. TECRL , a new life‐threatening inherited arrhythmia gene associated with overlapping clinical features of both LQTS and CPVT

    Article • EMBO Molecular Medicine, October 2016, EMBO

    Dr Abdelaziz Beqqali

  10. RBM20 Regulates Circular RNA Production From the Titin Gene

    Article • Circulation Research, August 2016, Wolters Kluwer Health

    Dr Abdelaziz Beqqali

  11. A mutation in the glutamate-rich region of RNA-binding motif protein 20 causes dilated cardiomyopathy through missplicing of titin and impaired Frank–Starling mechanism

    Article • Cardiovascular Research, August 2016, European Society of Cardiology

    Dr Abdelaziz Beqqali

  12. A targeted metabolomics assay for cardiac metabolism and demonstration using a mouse model of dilated cardiomyopathy

    Article • Metabolomics, March 2016, Springer Science + Business Media

    Dr Abdelaziz Beqqali

  13. Long Non-Coding RNA Malat-1 Is Dispensable during Pressure Overload-Induced Cardiac Remodeling and Failure in Mice

    Article • PLoS ONE, February 2016, PLOS

    Dr Abdelaziz Beqqali

  14. Insights into alternative splicing of sarcomeric genes in the heart

    Article • Journal of Molecular and Cellular Cardiology, April 2015, Elsevier

    Dr Abdelaziz Beqqali

  15. The LMNA mutation p.Arg321Ter associated with dilated cardiomyopathy leads to reduced expression and a skewed ratio of lamin A and lamin C proteins

    Article • Experimental Cell Research, November 2013, Elsevier

    Dr Abdelaziz Beqqali

  16. Sarcosin (Krp1) in skeletal muscle differentiation: gene expression profiling and knockdown experiments

    Article • The International Journal of Developmental Biology, January 2012, UBC Press

    Dr Abdelaziz Beqqali

  17. Cytoskeletal heart-enriched actin-associated protein (CHAP) is expressed in striated and smooth muscle cells in chick and mouse during embryonic and adult stages

    Article • The International Journal of Developmental Biology, January 2011, UBC Press

    Dr Abdelaziz Beqqali

  18. CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function

    Article • Journal of Cell Science, March 2010, The Company of Biologists

    Dr Abdelaziz Beqqali

  19. CAZIP, a novel protein expressed in the developing heart and nervous system

    Article • Developmental Dynamics, November 2009, Wiley

    Dr Abdelaziz Beqqali

  20. Human stem cells as a model for cardiac differentiation and disease

    Article • Cellular and Molecular Life Sciences, January 2009, Springer Science + Business Media

    Dr Abdelaziz Beqqali

  21. Genome-Wide Transcriptional Profiling of Human Embryonic Stem Cells Differentiating to Cardiomyocytes

    Article • Stem Cells, August 2006, Wiley

    Dr Abdelaziz Beqqali