All Stories

  1. Activation of immune cell proteasomes in peripheral blood of smokers and COPD patients: implications for therapy

    Article • European Respiratory Journal, September 2021, European Respiratory Society (ERS)

    Dr Silke Meiners

  2. Altered proteasome function in right ventricular hypertrophy

    Article • Cardiovascular Research, April 2019, Oxford University Press (OUP)

    Dr Silke Meiners

  3. Early injury of the neonatal lung contributes to premature lung aging: a hypothesis

    Article • Molecular and Cellular Pediatrics, July 2016, Springer Science + Business Media

    Dr Silke Meiners

  4. Proteasome function shapes innate and adaptive immune responses

    Article • AJP Lung Cellular and Molecular Physiology, June 2016, American Physiological Society

    Dr Silke Meiners

  5. Proteasome function in lung disease

    Article • American Review of Respiratory Disease, June 2016, American Thoracic Society

    Dr Silke Meiners, Darcy Wagner

  6. Inhibition of Proteasome Activity Induces Formation of Alternative Proteasome Complexes

    Article • Journal of Biological Chemistry, April 2016, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Silke Meiners

  7. Lung cancer nanomedicine: potentials and pitfalls

    Article • Nanomedicine, November 2015, Future Medicine

    Dr Silke Meiners

  8. Regulation of 26S Proteasome Activity in Pulmonary Fibrosis

    Article • American Review of Respiratory Disease, November 2015, American Thoracic Society

    Dr Silke Meiners

  9. Proteasome function is not impaired in healthy aging of the lung

    Article • Aging, October 2015, Impact Journals, LLC

    Dr Silke Meiners

  10. Validation of the 2nd Generation Proteasome Inhibitor Oprozomib for Local Therapy of Pulmonary Fibrosis

    Article • PLoS ONE, September 2015, PLOS

    Dr Silke Meiners

  11. LSC Abstract – Cigarette smoke impairs proteasome-dependent MHC I antigen presentation

    Article • September 2015, European Respiratory Society (ERS)

    Dr Silke Meiners

  12. Validated prediction of pro-invasive growth factors using a transcriptome-wide invasion signature derived from a complex 3D invasion assay

    Article • Scientific Reports, August 2015, Nature

    Dr Silke Meiners

  13. Regulation of Immunoproteasome Function in the Lung

    Article • Scientific Reports, May 2015, Nature

    Dr Silke Meiners

  14. Protease-Mediated Release of Chemotherapeutics from Mesoporous Silica Nanoparticles to ex Vivo Human and Mouse Lung Tumors

    Article • ACS Nano, March 2015, American Chemical Society (ACS)

    Dr Silke Meiners

  15. Hallmarks of the ageing lung

    Article • European Respiratory Journal, February 2015, European Respiratory Society (ERS)

    Dr Silke Meiners

  16. Blue Journal Conference. Aging and Susceptibility to Lung Disease

    Article • American Review of Respiratory Disease, February 2015, American Thoracic Society

    Dr Silke Meiners

  17. Regulation of the Proteasome: Evaluating the Lung Proteasome as a New Therapeutic Target

    Article • Antioxidants & Redox Signaling, December 2014, Mary Ann Liebert Inc

    Dr Silke Meiners

  18. Proteostasis in pediatric pulmonary pathology

    Article • Molecular and Cellular Pediatrics, December 2014, Springer Science + Business Media

    Dr Silke Meiners

  19. Efficient Bioactive Delivery of Aerosolized Drugs to Human Pulmonary Epithelial Cells Cultured in Air–Liquid Interface Conditions

    Article • American Journal of Respiratory Cell and Molecular Biology, October 2014, American Thoracic Society

    Dr Silke Meiners

  20. Critical role of interleukin 1 for the initiation and resolution of pulmonary inflammation induced by carbon nanomaterials

    Article • Toxicology Letters, September 2014, Elsevier

    Dr Silke Meiners

  21. Cigarette Smoke–Induced Disruption of Bronchial Epithelial Tight Junctions Is Prevented by Transforming Growth Factor-β

    Article • American Journal of Respiratory Cell and Molecular Biology, June 2014, American Thoracic Society

    Dr Silke Meiners

  22. Epigenetic mechanisms in COPD: implications for pathogenesis and drug discovery

    Article • Expert Opinion on Drug Discovery, May 2014, Informa Healthcare

    Dr Silke Meiners

  23. Protein Quality Control Coming of Age

    Article • March 2014, Wiley

    Dr Silke Meiners

  24. Molecular Aspects of Aging

    Article • March 2014, Wiley

    Dr Silke Meiners

  25. Comparative proteome analysis of lung tissue from patients with idiopathic pulmonary fibrosis (IPF), non-specific interstitial pneumonia (NSIP) and organ donors

    Article • Journal of Proteomics, June 2013, Elsevier

    Dr Silke Meiners

  26. Low Dose Proteasome Inhibition Affects Alternative Splicing

    Article • Journal of Proteome Research, August 2012, American Chemical Society (ACS)

    Dr Silke Meiners

  27. Acute Effect Of Cigarette Smoke On Proteasome Function

    Article • May 2012, American Thoracic Society

    Dr Silke Meiners

  28. What shall we do with the damaged proteins in lung disease? Ask the proteasome!

    Article • European Respiratory Journal, March 2012, European Respiratory Society (ERS)

    Dr Silke Meiners

  29. Next-generation personalized drug discovery: the tripeptide GHK hits center stage in chronic obstructive pulmonary disease

    Article • Genome Medicine, January 2012, Springer Science + Business Media

    Dr Silke Meiners

  30. Characterization Of The Proteasome In Normal And COPD Diseased Lungs

    Article • May 2011, American Thoracic Society

    Dr Silke Meiners

  31. Human-specific induction of glutathione peroxidase-3 by proteasome inhibition in cardiovascular cells

    Article • Free Radical Biology and Medicine, December 2009, Elsevier

    Dr Silke Meiners

  32. Proteasome inhibition prevents experimentally-induced endothelial dysfunction

    Article • Life Sciences, June 2009, Elsevier

    Dr Silke Meiners

  33. Comprehensive proteomic and transcriptomic analysis reveals early induction of a protective anti-oxidative stress response by low-dose proteasome inhibition

    Article • PROTEOMICS, June 2009, Wiley

    Dr Silke Meiners

  34. Potent anti-inflammatory effects of low-dose proteasome inhibition in the vascular system

    Article • Journal of Molecular Medicine, April 2009, Springer Science + Business Media

    Dr Silke Meiners

  35. ChemInform Abstract: Proteasome Inhibitors: Poisons and Remedies

    Article • ChemInform, June 2008, Wiley

    Dr Silke Meiners

  36. Markers of instability in high-risk carotid plaques are reduced by statins

    Article • Journal of Vascular Surgery, March 2008, Elsevier

    Dr Silke Meiners

  37. Proteasome inhibitors: Poisons and remedies

    Article • Medicinal Research Reviews, January 2008, Wiley

    Dr Silke Meiners

  38. Role of HGF/SF and c-Met in Morphogenesis and Metastasis of Epithelial Cells

    Article • September 2007, Wiley

    Dr Silke Meiners

  39. Screening of the Dose-Dependent Effects of Proteasome Inhibition by a Proteomic and Transcriptomic Approach

    Article • September 2007, Elsevier

    Dr Silke Meiners

  40. Low-dose renin inhibitor and low-dose AT1-receptor blocker therapy ameliorate target-organ damage in rats harbouring human renin and angiotensinogen genes

    Article • Journal of the Renin-Angiotensin-Aldosterone System, June 2007, SAGE Publications

    Dr Silke Meiners

  41. Nontoxic proteasome inhibition activates a protective antioxidant defense response in endothelial cells

    Article • Free Radical Biology and Medicine, June 2006, Elsevier

    Dr Silke Meiners

  42. Ongoing Coxsackievirus Myocarditis Is Associated with Increased Formation and Activity of Myocardial Immunoproteasomes

    Article • American Journal Of Pathology, May 2006, Elsevier

    Dr Silke Meiners

  43. Inhibition of the Ubiquitin-Proteasome System Protects Endothelial Cells from Oxidative Stress

    Article • April 2006, Elsevier

    Dr Silke Meiners

  44. Proteasome inhibitors induce antioxidative enzymes and confer cardioprotection against oxidative stress

    Article • April 2006, Elsevier

    Dr Silke Meiners

  45. Effect of statins on the proteasomal activity in mammalian endothelial and vascular smooth muscle cells

    Article • Biochemical Pharmacology, August 2005, Elsevier

    Dr Silke Meiners

  46. Cardiac gene expression profile in rats with terminal heart failure and cachexia

    Article • Physiological Genomics, December 2004, American Physiological Society

    Dr Silke Meiners

  47. The tea flavonoid epigallocatechin-3-gallate reduces cytokine-induced VCAM-1 expression and monocyte adhesion to endothelial cells

    Article • Biochemical and Biophysical Research Communications, April 2004, Elsevier

    Dr Silke Meiners

  48. Inhibition of chemokine production from human airway smooth muscle cells by fluticasone, budesonide and beclomethasone

    Article • Pulmonary Pharmacology & Therapeutics, February 2004, Elsevier

    Dr Silke Meiners

  49. Inhibition of the Ubiquitin-Proteasome Pathway Induces Differential Heat-Shock Protein Response in Cardiomyocytes and Renders Early Cardiac Protection

    Article • Biochemical and Biophysical Research Communications, March 2002, Elsevier

    Dr Silke Meiners

  50. Role of morphogenetic factors in metastasis of mammary carcinoma cells

    Article • Oncogene, January 1998, Nature

    Dr Silke Meiners