All Stories

  1. In transcription antitermination by Qλ, NusA induces refolding of Qλ to form a nozzle that extends the RNA polymerase RNA-exit channel

    Article • Proceedings of the National Academy of Sciences, August 2022, Proceedings of the National Academy of Sciences

    Richard Ebright

  2. Structural and mechanistic basis of reiterative transcription initiation

    Article • Proceedings of the National Academy of Sciences, January 2022, Proceedings of the National Academy of Sciences

    Richard Ebright

  3. Closing and opening of the RNA polymerase trigger loop

    Article • Proceedings of the National Academy of Sciences, June 2020, Proceedings of the National Academy of Sciences

    Richard Ebright

  4. Novel RNA polymerase inhibitor found in soil extracts provides hope for future antibacterial drugs

    Article • Future Medicinal Chemistry, October 2017, Future Science

    Richard Ebright

  5. Crystal structure of Escherichia coli RNA polymerase in complex with salinamide A

    Article • May 2014, Protein Data Bank, Rutgers University

    Richard Ebright

  6. Crystal structure of Escherichia coli RNA polymerase holoenzyme

    Article • May 2014, Protein Data Bank, Rutgers University

    Richard Ebright

  7. Crystal structure of Thermus thermophilus transcription initiation complex soaked with GE23077, ATP, and CMPcPP

    Article • May 2014, Protein Data Bank, Rutgers University

    Richard Ebright

  8. Crystal structure of Thermus thermophilus transcription initiation complex soaked with GE23077 and rifampicin

    Article • May 2014, Protein Data Bank, Rutgers University

    Richard Ebright

  9. Crystal structure of Thermus thermophilus RNA polymerase transcription initiation complex soaked with GE23077 and rifamycin SV

    Article • May 2014, Protein Data Bank, Rutgers University

    Richard Ebright

  10. Crystal structure of Thermus thermophilus transcription initiation complex soaked with GE23077

    Article • May 2014, Protein Data Bank, Rutgers University

    Richard Ebright

  11. Crystal structure of Thermus thermophilus pre-insertion substrate complex for de novo transcription initiation

    Article • May 2014, Protein Data Bank, Rutgers University

    Richard Ebright

  12. Crystal structure of Thermus thermophilus RNA polymerase holoenzyme in complex with GE23077

    Article • May 2014, Protein Data Bank, Rutgers University

    Richard Ebright

  13. Transcription inhibition by the depsipeptide antibiotic salinamide A

    Article • eLife, April 2014, eLife

    Richard Ebright

  14. GE23077 binds to the RNA polymerase ‘i’ and ‘i+1’ sites and prevents the binding of initiating nucleotides

    Article • eLife, April 2014, eLife

    Richard Ebright, Dr Rolf Jansen, Dr Elena V Sineva

  15. Structure of the DNA-Binding and RNA-Polymerase-Binding Region of Transcription Antitermination Factor λQ

    Article • Structure, March 2014, Elsevier

    Richard Ebright

  16. Crystal structure of antitermination protein Q from bacteriophage lambda. Northeast Structural Genomics Consortium target OR18A.

    Article • September 2013, Protein Data Bank, Rutgers University

    Richard Ebright

  17. The Transcription Bubble of the RNA Polymerase–Promoter Open Complex Exhibits Conformational Heterogeneity and Millisecond-Scale Dynamics: Implications for Transcription Start-Site Selection

    Article • Journal of Molecular Biology, March 2013, Elsevier

    Richard Ebright

  18. Flexibility in Transcription Start-Site Selection by RNA Polymerase Involves Transcription-Bubble Expansion (“Scrunching”) or Contraction (“Unscrunching”)

    Article • Biophysical Journal, January 2013, Elsevier

    Richard Ebright

  19. Crystal structure of Thermus thermophilus transcription initiation complex

    Article • October 2012, Protein Data Bank, Rutgers University

    Richard Ebright

  20. Crystal structure of Thermus thermophilus transcription initiation complex containing 5-BrU at template-strand position +1

    Article • October 2012, Protein Data Bank, Rutgers University

    Richard Ebright

  21. Crystal structure of Thermus thermophilus transcription initiation complex containing 2 nt of RNA

    Article • October 2012, Protein Data Bank, Rutgers University

    Richard Ebright

  22. Structural Basis of Transcription Initiation

    Article • Science, October 2012, American Association for the Advancement of Science

    Richard Ebright

  23. Frequency, Spectrum, and Nonzero Fitness Costs of Resistance to Myxopyronin in Staphylococcus aureus

    Article • Antimicrobial Agents and Chemotherapy, September 2012, ASM Journals

    Richard Ebright

  24. Opening and Closing of the Bacterial RNA Polymerase Clamp

    Article • Science, August 2012, American Association for the Advancement of Science

    Richard Ebright

  25. Erratum to “Structure of the CAP–DNA Complex at 2.5 Å Resolution: A Complete Picture of the Protein–DNA Interface” [J. Mol. Biol. 260/3 (1996) 395–408]

    Article • Journal of Molecular Biology, November 2011, Elsevier

    Richard Ebright

  26. Special Issue: Mechanisms of Transcription

    Article • Journal of Molecular Biology, October 2011, Elsevier

    Richard Ebright

  27. New target for inhibition of bacterial RNA polymerase: ‘switch region’

    Article • Current Opinion in Microbiology, October 2011, Elsevier

    Richard Ebright, Dr Elena V Sineva

  28. The Antibacterial Threaded-lasso Peptide Capistruin Inhibits Bacterial RNA Polymerase

    Article • Journal of Molecular Biology, October 2011, Elsevier

    Richard Ebright

  29. Antibiotic Production by Myxobacteria Plays a Role in Predation

    Article • Journal of Bacteriology, July 2011, ASM Journals

    Richard Ebright, Professor Daniel Wall

  30. The Initiation Factor TFE and the Elongation Factor Spt4/5 Compete for the RNAP Clamp during Transcription Initiation and Elongation

    Article • Molecular Cell, July 2011, Elsevier

    Richard Ebright

  31. Azide-Specific Labeling of Biomolecules by Staudinger–Bertozzi Ligation

    Article • January 2010, Elsevier

    Richard Ebright

  32. Structures of RNA polymerase–antibiotic complexes

    Article • Current Opinion in Structural Biology, December 2009, Elsevier

    Richard Ebright

  33. Three-dimensional EM structure of an intact activator-dependent transcription initiation complex

    Article • Proceedings of the National Academy of Sciences, November 2009, Proceedings of the National Academy of Sciences

    Richard Ebright

  34. Direct Detection of Abortive RNA Transcripts in Vivo

    Article • Science, May 2009, American Association for the Advancement of Science

    Richard Ebright

  35. Structural basis for cAMP-mediated allosteric control of the catabolite activator protein

    Article • Proceedings of the National Academy of Sciences, April 2009, Proceedings of the National Academy of Sciences

    Richard Ebright

  36. Single-Molecule Analysis of Transcription

    Article • Biophysical Journal, February 2009, Elsevier

    Richard Ebright

  37. Static and Kinetic Site-Specific Protein-DNA Photocrosslinking: Analysis of Bacterial Transcription Initiation Complexes

    Article • January 2009, Springer Science + Business Media

    Richard Ebright

  38. The RNA Polymerase “Switch Region” Is a Target for Inhibitors

    Article • Cell, October 2008, Elsevier

    Richard Ebright

  39. Rifamycins do not function by allosteric modulation of binding of Mg 2+ to the RNA polymerase active center

    Article • Proceedings of the National Academy of Sciences, September 2008, Proceedings of the National Academy of Sciences

    Richard Ebright

  40. Nonradioactive, ultrasensitive site-specific protein-protein photocrosslinking: interactions of  -helix 2 of TATA-binding protein with general transcription factor TFIIA and transcriptional repressor NC2

    Article • Nucleic Acids Research, September 2008, Oxford University Press (OUP)

    Richard Ebright

  41. Systematic Structure-Activity Analysis of Microcin J25

    Article • Journal of Biological Chemistry, July 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Richard Ebright, Dr Elena V Sineva

  42. Upstream promoter sequences and αCTD mediate stable DNA wrapping within the RNA polymerase–promoter open complex

    Article • EMBO Reports, February 2007, EMBO

    Richard Ebright

  43. Abortive Initiation and Productive Initiation by RNA Polymerase Involve DNA Scrunching

    Article • Science, November 2006, American Association for the Advancement of Science

    Richard Ebright, Dr Terence R Strick

  44. Initial Transcription by RNA Polymerase Proceeds Through a DNA-Scrunching Mechanism

    Article • Science, November 2006, American Association for the Advancement of Science

    Richard Ebright

  45. Site-Specific Protein-DNA Photo-Cross-Linking: Analysis of Structural Organization of Protein-DNA and Multiprotein-DNA Complexes

    Article • Cold Spring Harbor Protocols, November 2006, Cold Spring Harbor Laboratory Press

    Richard Ebright

  46. Dynamically driven protein allostery

    Article • Nature Structural & Molecular Biology, August 2006, Springer Science + Business Media

    Richard Ebright

  47. Thermodynamic and kinetic modeling of transcriptional pausing

    Article • Proceedings of the National Academy of Sciences, March 2006, Proceedings of the National Academy of Sciences

    Richard Ebright

  48. Indirect Readout of DNA Sequence at the Primary-kink Site in the CAP–DNA Complex: Recognition of Pyrimidine-Purine and Purine-Purine Steps

    Article • Journal of Molecular Biology, March 2006, Elsevier

    Richard Ebright

  49. Direct Observation of Abortive Initiation and Promoter Escape within Single Immobilized Transcription Complexes

    Article • Biophysical Journal, February 2006, Elsevier

    Richard Ebright

  50. Retention of Transcription Initiation Factor σ70 in Transcription Elongation: Single-Molecule Analysis

    Article • Molecular Cell, November 2005, Elsevier

    Richard Ebright

  51. Inhibition of Bacterial RNA Polymerase by Streptolydigin: Stabilization of a Straight-Bridge-Helix Active-Center Conformation

    Article • Cell, August 2005, Elsevier

    Richard Ebright, Dr Elena V Sineva

  52. Accurate FRET Measurements within Single Diffusing Biomolecules Using Alternating-Laser Excitation

    Article • Biophysical Journal, April 2005, Elsevier

    Richard Ebright

  53. The interaction between σ 70 and the β-flap of Escherichia coli RNA polymerase inhibits extension of nascent RNA during early elongation

    Article • Proceedings of the National Academy of Sciences, March 2005, Proceedings of the National Academy of Sciences

    Richard Ebright

  54. Single-molecule DNA nanomanipulation: Improved resolution through use of shorter DNA fragments

    Article • Nature Methods, February 2005, Springer Science + Business Media

    Richard Ebright, Dr Terence R Strick

  55. Distance-Restrained Docking of Rifampicin and Rifamycin SV to RNA Polymerase Using Systematic FRET Measurements: Developing Benchmarks of Model Quality and Reliability

    Article • Biophysical Journal, February 2005, Elsevier

    Richard Ebright

  56. Antibacterial Peptide Microcin J25 Inhibits Transcription by Binding within and Obstructing the RNA Polymerase Secondary Channel

    Article • Molecular Cell, June 2004, Elsevier

    Richard Ebright, Dr Elena V Sineva

  57. The σ70 subunit of RNA polymerase mediates a promoter-proximal pause at the lac promoter

    Article • Nature Structural & Molecular Biology, May 2004, Springer Science + Business Media

    Richard Ebright

  58. Promoter unwinding and promoter clearance by RNA polymerase: Detection by single-molecule DNA nanomanipulation

    Article • Proceedings of the National Academy of Sciences, March 2004, Proceedings of the National Academy of Sciences

    Richard Ebright, Dr Terence R Strick

  59. Catabolite activator protein: DNA binding and transcription activation

    Article • Current Opinion in Structural Biology, February 2004, Elsevier

    Richard Ebright

  60. Structure of Antibacterial Peptide Microcin J25:  A 21-Residue Lariat Protoknot

    Article • Journal of the American Chemical Society, September 2003, American Chemical Society (ACS)

    Richard Ebright, Dr Elena V Sineva

  61. Functional Interaction between RNA Polymerase α Subunit C-Terminal Domain and σ70 in UP-Element- and Activator-Dependent Transcription

    Article • Molecular Cell, June 2003, Elsevier

    Richard Ebright

  62. Fluorescence Resonance Energy Transfer (FRET) in Analysis of Transcription-Complex Structure and Function

    Article • January 2003, Elsevier

    Richard Ebright

  63. Single-Molecule DNA Nanomanipulation: Detection of Promoter-Unwinding Events by RNA Polymerase

    Article • January 2003, Elsevier

    Richard Ebright, Dr Terence R Strick

  64. Determinants of the C-Terminal Domain of the Escherichia coli RNA Polymerase α Subunit Important for Transcription at Class I Cyclic AMP Receptor Protein-Dependent Promoters

    Article • Journal of Bacteriology, April 2002, ASM Journals

    Richard Ebright

  65. Structural Organization of Bacterial RNA Polymerase Holoenzyme and the RNA Polymerase-Promoter Open Complex

    Article • Cell, March 2002, Elsevier

    Richard Ebright

  66. Bioweapon agents: more access means more risk

    Article • Nature, January 2002, Springer Science + Business Media

    Richard Ebright

  67. PROTEIN-DNA RECOGNITION AND DNA DEFORMATION REVEALED IN CRYSTAL STRUCTURES OF CAP-DNA COMPLEXES

    Article • November 2001, Protein Data Bank, Rutgers University

    Richard Ebright

  68. PROTEIN-DNA RECOGNITION AND DNA DEFORMATION REVEALED IN CRYSTAL STRUCTURES OF CAP-DNA COMPLEXES

    Article • November 2001, Protein Data Bank, Rutgers University

    Richard Ebright

  69. PROTEIN-DNA RECOGNITION AND DNA DEFORMATION REVEALED IN CRYSTAL STRUCTURES OF CAP-DNA COMPLEXES

    Article • November 2001, Protein Data Bank, Rutgers University

    Richard Ebright

  70. PROTEIN-DNA RECOGNITION AND DNA DEFORMATION REVEALED IN CRYSTAL STRUCTURES OF CAP-DNA COMPLEXES

    Article • November 2001, Protein Data Bank, Rutgers University

    Richard Ebright

  71. Site-Specific Incorporation of Fluorescent Probes into Protein:  Hexahistidine-Tag-Mediated Fluorescent Labeling with (Ni2+:Nitrilotriacetic Acid)n−Fluorochrome Conjugates

    Article • Journal of the American Chemical Society, November 2001, American Chemical Society (ACS)

    Richard Ebright

  72. Indirect readout of DNA sequence at the primary-kink site in the CAP-DNA complex: DNA binding specificity based on energetics of DNA kinking

    Article • Journal of Molecular Biology, November 2001, Elsevier

    Richard Ebright

  73. Indirect readout of DNA sequence at the primary-kink site in the CAP-DNA complex: alteration of DNA binding specificity through alteration of DNA kinking

    Article • Journal of Molecular Biology, November 2001, Elsevier

    Richard Ebright

  74. Mean DNA Bend Angle and Distribution of DNA Bend Angles in the CAP-DNA Complex in Solution

    Article • Journal of Molecular Biology, September 2001, Elsevier

    Richard Ebright

  75. Bacterial RNA polymerase subunit ω and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly

    Article • Proceedings of the National Academy of Sciences, January 2001, Proceedings of the National Academy of Sciences

    Richard Ebright

  76. RNA Polymerase: Structural Similarities Between Bacterial RNA Polymerase and Eukaryotic RNA Polymerase II

    Article • Journal of Molecular Biology, December 2000, Elsevier

    Richard Ebright

  77. Structural Organization of the RNA Polymerase-Promoter Open Complex

    Article • Cell, June 2000, Elsevier

    Richard Ebright

  78. Transcription activation by catabolite activator protein (CAP)

    Article • Journal of Molecular Biology, October 1999, Elsevier

    Richard Ebright

  79. Bacterial promoter architecture: subsite structure of UP elements and interactions with the carboxy-terminal domain of the RNA polymerase alpha subunit

    Article • Genes & Development, August 1999, Cold Spring Harbor Laboratory Press

    Richard Ebright

  80. Orientation of OmpR monomers within an OmpR:DNA complex determined by DNA affinity cleaving 1 1Edited by K. Yamamoto

    Article • Journal of Molecular Biology, January 1999, Elsevier

    Richard Ebright

  81. Mutational analysis of a transcriptional activation region of the VP16 protein of herpes simplex virus

    Article • Nucleic Acids Research, December 1998, Oxford University Press (OUP)

    Richard Ebright

  82. RNA Polymerase-DNA Interaction: Structures of Intermediate, Open, and Elongation Complexes

    Article • Cold Spring Harbor Symposia on Quantitative Biology, January 1998, Cold Spring Harbor Laboratory Press

    Richard Ebright

  83. New core promoter element in RNA polymerase II-dependent transcription: sequence-specific DNA binding by transcription factor IIB

    Article • Genes & Development, January 1998, Cold Spring Harbor Laboratory Press

    Richard Ebright

  84. Mechanisms of Viral Activators

    Article • Cold Spring Harbor Symposia on Quantitative Biology, January 1998, Cold Spring Harbor Laboratory Press

    Richard Ebright

  85. The RNA Polymerase II General Transcription Factors: Past, Present, and Future

    Article • Cold Spring Harbor Symposia on Quantitative Biology, January 1998, Cold Spring Harbor Laboratory Press

    Richard Ebright

  86. Trajectory of DNA in the RNA polymerase II transcription preinitiation complex

    Article • Proceedings of the National Academy of Sciences, November 1997, Proceedings of the National Academy of Sciences

    Richard Ebright

  87. Transcription activation at Class II CAP‐dependent promoters

    Article • Molecular Microbiology, March 1997, Wiley

    Richard Ebright

  88. Aromatic hydrogen bond in sequence-specific protein DNA recognition

    Article • Nature Structural & Molecular Biology, October 1996, Springer Science + Business Media

    Richard Ebright

  89. High-resolution mapping of nucleoprotein complexes by site-specific protein-DNA photocrosslinking: organization of the human TBP-TFIIA-TFIIB-DNA quaternary complex.

    Article • Proceedings of the National Academy of Sciences, October 1996, Proceedings of the National Academy of Sciences

    Richard Ebright

  90. Determinants of RNA polymerase alpha subunit for interaction with beta, beta', and sigma subunits: hydroxyl-radical protein footprinting.

    Article • Proceedings of the National Academy of Sciences, September 1996, Proceedings of the National Academy of Sciences

    Richard Ebright

  91. STRUCTURE OF THE CAP-DNA COMPLEX AT 2.5 ANGSTROMS RESOLUTION: A COMPLETE PICTURE OF THE PROTEIN-DNA INTERFACE

    Article • July 1996, Protein Data Bank, Rutgers University

    Richard Ebright

  92. Structure of the CAP-DNA Complex at 2.5 Å Resolution: A Complete Picture of the Protein-DNA Interface

    Article • Journal of Molecular Biology, July 1996, Elsevier

    Richard Ebright

  93. A single substitution in the putative helix‐turn‐helix motif of the pleiotropic activator PrfA attenuates Listeria monocytogenes virulence

    Article • Molecular Microbiology, May 1996, Wiley

    Richard Ebright

  94. Protein-protein interactions in eukaryotic transcription initiation: structure of the preinitiation complex.

    Article • Proceedings of the National Academy of Sciences, February 1996, Proceedings of the National Academy of Sciences

    Richard Ebright

  95. S-[2-(4-Azidosalicylamido)ethylthio]-2-thiopyridine:  Radioiodinatable, Cleavable, Photoactivatible Cross-Linking Agent

    Article • Bioconjugate Chemistry, January 1996, American Chemical Society (ACS)

    Richard Ebright

  96. Structure of the LexA Repressor−DNA Complex Probed by Affinity Cleavage and Affinity Photo-Cross-Linking

    Article • Biochemistry, January 1996, American Chemical Society (ACS)

    Richard Ebright

  97. [10] Escherichia coli RNA polymerase holoenzyme: Rapid reconstitution from recombinant α, β, β′, and σ subunits

    Article • January 1996, Elsevier

    Richard Ebright

  98. Fluorescence anisotropy: Rapid, quantitative assay for protein-DNA and protein-protein interaction

    Article • January 1996, Elsevier

    Richard Ebright

  99. Artificial Sequence-Specific DNA Binding Peptides:  Branched-Chain Basic Regions

    Article • Journal of the American Chemical Society, January 1996, American Chemical Society (ACS)

    Richard Ebright

  100. DNA-binding determinants of the alpha subunit of RNA polymerase: novel DNA-binding domain architecture.

    Article • Genes & Development, January 1996, Cold Spring Harbor Laboratory Press

    Richard Ebright

  101. Rapid RNA polymerase genetics: one-day, no-column preparation of reconstituted recombinant Escherichia coli RNA polymerase.

    Article • Proceedings of the National Academy of Sciences, May 1995, Proceedings of the National Academy of Sciences

    Richard Ebright

  102. The Escherichia coli RNA polymerase α subunit: structure and function

    Article • Current Opinion in Genetics & Development, April 1995, Elsevier

    Richard Ebright

  103. Location, structure, and function of the target of a transcriptional activator protein.

    Article • Genes & Development, December 1994, Cold Spring Harbor Laboratory Press

    Richard Ebright

  104. Characterization of the activating region of Escherichia coli catabolite gene activator protein (CAP) I. Saturation and alanine-scanning mutagenesis

    Article • Journal of Molecular Biology, November 1994, Elsevier

    Richard Ebright

  105. Characterization of the activating region of Escherichia coli catabolite gene activator protein (CAP) II. Role at class I and class II CAP-dependent promoters

    Article • Journal of Molecular Biology, November 1994, Elsevier

    Richard Ebright

  106. Domain organization of RNA polymerase α subunit: C-terminal 85 amino acids constitute a domain capable of dimerization and DNA binding

    Article • Cell, September 1994, Elsevier

    Richard Ebright

  107. High-specificity DNA cleavage agent: design and application to kilobase and megabase DNA substrates

    Article • Science, August 1994, American Association for the Advancement of Science

    Richard Ebright

  108. Identification of the target of a transcription activator protein by protein-protein photocrosslinking

    Article • Science, July 1994, American Association for the Advancement of Science

    Richard Ebright

  109. DNA affinity cleaving analysis of homeodomain-DNA interaction: identification of homeodomain consensus sites in genomic DNA.

    Article • Proceedings of the National Academy of Sciences, January 1994, Proceedings of the National Academy of Sciences

    Richard Ebright

  110. CAP interacts with RNA polymerase in solution in the absence of promoter DNA

    Article • Nature, August 1993, Springer Science + Business Media

    Richard Ebright

  111. Identification of the activating region of catabolite gene activator protein (CAP): isolation and characterization of mutants of CAP specifically defective in transcription activation.

    Article • Proceedings of the National Academy of Sciences, July 1993, Proceedings of the National Academy of Sciences

    Richard Ebright

  112. Transcription activation at Class I CAP‐dependent promoters

    Article • Molecular Microbiology, May 1993, Wiley

    Richard Ebright

  113. N-(Iodoacetyl)-p-phenylenediamine-EDTA: A reagent for high-efficiency incorporation of an EDTA-metal complex at a rationally selected site within a protein

    Article • Bioconjugate Chemistry, May 1993, American Chemical Society (ACS)

    Richard Ebright

  114. Identification of the functional subunit of a dimeric transcription activator protein by use of oriented heterodimers

    Article • Cell, April 1993, Elsevier

    Richard Ebright

  115. Incorporation of an EDTA-metal complex at a rationally selected site within a protein: application to EDTA-iron DNA affinity cleaving with catabolite gene activator protein (CAP) and Cro

    Article • Biochemistry, November 1992, American Chemical Society (ACS)

    Richard Ebright

  116. Determination of the orientation of a DNA binding motif in a protein-DNA complex by photocrosslinking.

    Article • Proceedings of the National Academy of Sciences, November 1992, Proceedings of the National Academy of Sciences

    Richard Ebright

  117. Identification of an amino acid–base contact in the GCN4–DNA complex by bromouracil-mediated photocrosslinking

    Article • Nature, October 1992, Springer Science + Business Media

    Richard Ebright

  118. Corrected nucleotide sequence of M13mp18 gene III

    Article • Gene, May 1992, Elsevier

    Richard Ebright

  119. Derivatives of CAP Having No Solvent-Accessible Cysteine Residues, or Having a Unique Solvent-Accessible Cysteine Residue at Amino Acid 2 of the Helix-Turn-Helix Motif

    Article • Journal of Biomolecular Structure and Dynamics, December 1991, Taylor & Francis

    Richard Ebright

  120. [30] Identification of amino acid—base pair contacts by genetic methods

    Article • January 1991, Elsevier

    Richard Ebright

  121. Random mutagenesis of gene-sized DNA molecules by use of PCR with Taq DNA polymerase

    Article • Nucleic Acids Research, January 1991, Oxford University Press (OUP)

    Richard Ebright

  122. Orientation of the Lac repressor DNA binding domain in complex with the left lac operator half site characterized by affinity cleaving

    Article • Nucleic Acids Research, January 1991, Oxford University Press (OUP)

    Richard Ebright

  123. Identification of a contact between arginine-180 of the catabolite gene activator protein (CAP) and base pair 5 of the DNA site in the CAP-DNA complex.

    Article • Proceedings of the National Academy of Sciences, June 1990, Proceedings of the National Academy of Sciences

    Richard Ebright

  124. Conversion of a helix-turn-helix motif sequence-specific DNA binding protein into a site-specific DNA cleavage agent.

    Article • Proceedings of the National Academy of Sciences, April 1990, Proceedings of the National Academy of Sciences

    Richard Ebright

  125. DNA-sequence recognition by CAP: role of the adenine N 6 atom of base pair 6 of the DNA site

    Article • Nucleic Acids Research, January 1990, Oxford University Press (OUP)

    Richard Ebright

  126. Lysine 188 of the catabolite gene activator protein (CAP) plays no role in specificity at base pair 7 of the DNA half site

    Article • Nucleic Acids Research, January 1990, Oxford University Press (OUP)

    Richard Ebright

  127. Consensus DNA site for the Escherichia coli catabolite gene activator protein (CAP): CAP exhibits a 450-fold higher affinity for the consensus DNA site than for the E.coli lac DNA site

    Article • Nucleic Acids Research, January 1989, Oxford University Press (OUP)

    Richard Ebright

  128. Role of glutamic acid-181 in DNA-sequence recognition by the catabolite gene activator protein (CAP) of Escherichia coli: altered DNA-sequence-recognition properties of [Val181]CAP and [Leu181]CAP.

    Article • Proceedings of the National Academy of Sciences, September 1987, Proceedings of the National Academy of Sciences

    Richard Ebright

  129. Classical genetics and site directed mutagenesis in the study of the specific interaction with DNA of CAP, the cyclic AMP receptor protein in E. coli K 12

    Article • Journal of Molecular Graphics, December 1986, Elsevier

    Richard Ebright

  130. Evidence for a contact between glutamine-18 of lac repressor and base pair 7 of lac operator.

    Article • Proceedings of the National Academy of Sciences, January 1986, Proceedings of the National Academy of Sciences

    Richard Ebright

  131. Use of “Loss-of-Contact” Substitutions to Identify Residues Involved in an Amino Acid-Base Pair Contact: Effect of Substitution of Gln18 of Lac Repressor by Gly, Ser, and Leu

    Article • Journal of Biomolecular Structure and Dynamics, October 1985, Taylor & Francis

    Richard Ebright

  132. The catabolite gene activator protein (CAP) is not required for indole-3-acetic acid to activate transcription of the araBAD operon of Escherichia coli K-12

    Article • MGG Molecular & General Genetics, September 1985, Springer Science + Business Media

    Richard Ebright

  133. Analogs of cyclic AMP that elicit the biochemically defined conformational change in catabolite gene activator protein (CAP) but do not stimulate binding to DNA

    Article • Journal of Molecular Biology, March 1985, Elsevier

    Richard Ebright

  134. Molecular basis of DNA sequence recognition by the catabolite gene activator protein: detailed inferences from three mutations that alter DNA sequence specificity.

    Article • Proceedings of the National Academy of Sciences, December 1984, Proceedings of the National Academy of Sciences

    Richard Ebright

  135. Mutations that alter the DNA sequence specificity of the catabolite gene activator protein of E. coli

    Article • Nature, September 1984, Springer Science + Business Media

    Richard Ebright

  136. Steroid Hormone Action Interpreted from X-Ray Crystallographic Studies

    Article • January 1984, Elsevier

    Richard Ebright

  137. Mechanism for transcriptional action of cyclic AMP in Escherichia coli: entry into DNA to disrupt DNA secondary structure.

    Article • Proceedings of the National Academy of Sciences, July 1981, Proceedings of the National Academy of Sciences

    Richard Ebright

  138. Site-Specific Protein-DNA Photocrosslinking: Analysis of Bacterial Transcription Initiation Complexes

    Article • Springer Science + Business Media

    Richard Ebright

  139. Conversion Of Helix-turn-helix Motif Sequence-specific DNA Binding Proteins Into Site-specific DNA Cleavage Agents

    Article • Institute of Electrical & Electronics Engineers (IEEE)

    Richard Ebright