All Stories

  1. Neuronal APOE4 removal protects against tau-mediated gliosis, neurodegeneration and myelin deficits
  2. Author Correction: Experimental and real-world evidence supporting the computational repurposing of bumetanide for APOE4-related Alzheimer’s disease
  3. Experimental and real-world evidence supporting the computational repurposing of bumetanide for APOE4-related Alzheimer’s disease
  4. Aβ initiates brain hypometabolism, network dysfunction and behavioral abnormalities via NOX2-induced oxidative stress in mice
  5. Adult trkB Signaling in Parvalbumin Interneurons is Essential to Prefrontal Network Dynamics
  6. Dentate Gyrus and CA3 GABAergic Interneurons Bidirectionally Modulate Signatures of Internal and External Drive to CA1
  7. Aβ-induced NOX2 activation underlies oxidative stress leading to brain hypometabolism and hyperactivity in Alzheimer's disease
  8. HCN channel activity balances quiescence and proliferation in neural stem cells and is a selective target for neuroprotection during cancer treatment.
  9. In Vivo Chimeric Alzheimer’s Disease Modeling of Apolipoprotein E4 Toxicity in Human Neurons
  10. A critical role for trkB signaling in the adult function of parvalbumin interneurons and prefrontal network dynamics
  11. Seizure-induced reduction in glucose utilization promotes brain hypometabolism during epileptogenesis
  12. Metabolic correction by pyruvate halts acquired epilepsy in multiple rodent models
  13. The vicious circle of hypometabolism in neurodegenerative diseases: Ways and mechanisms of metabolic correction
  14. Chronic inhibition of brain glycolysis initiates epileptogenesis
  15. Reality of Inhibitory GABA in Neonatal Brain: Time to Rewrite the Textbooks?
  16. Triple-target treatment for Alzheimer’s: Correcting hypometabolism, oxidative stress, and neuroinflammation
  17. Chemically defined, albumin-free human cardiomyocyte generation
  18. Amyloid- -Induced Action Potential Desynchronization and Degradation of Hippocampal Gamma Oscillations Is Prevented by Interference with Peptide Conformation Change and Aggregation
  19. Glycolysis and Oxidative Phosphorylation in Neurons and Astrocytes during Network Activity in Hippocampal Slices
  20. Dietary energy substrates reverse early neuronal hyperactivity in a mouse model of Alzheimer's disease
  21. Molecular reorganization of endocannabinoid signalling in Alzheimer's disease
  22. En masse in vitro functional profiling of the axonal mechanosensitivity of sensory neurons
  23. Secretagogin is a Ca 2+ -binding protein specifying subpopulations of telencephalic neurons
  24. beta-amyloid triggers neuronal hyper-activation and results in Alzheimer's-related epilepsy
  25. Input Specificity and Dependence of Spike Timing-Dependent Plasticity on Preceding Postsynaptic Activity at Unitary Connections between Neocortical Layer 2/3 Pyramidal Cells
  26. System A Transporter SAT2 Mediates Replenishment of Dendritic Glutamate Pools Controlling Retrograde Signaling by Glutamate
  27. GABAergic control of backpropagating action potentials in striatal medium spiny neurons
  28. Non-fibrillar β-amyloid abates spike-timing-dependent synaptic potentiation at excitatory synapses in layer 2/3 of the neocortex by targeting postsynaptic AMPA receptors