All Stories

  1. Elucidation of the dynamic nature of interactome networks: A practical tutorial

    Article • Journal of Proteomics, January 2018, Elsevier

    Dr Henrique Girao

  2. Role of connexin 43 in different forms of intercellular communication – gap junctions, extracellular vesicles and tunnelling nanotubes

    Article • Journal of Cell Science, October 2017, The Company of Biologists

    Dr Henrique Girao

  3. MicroRNA-424(322) as a new marker of disease progression in pulmonary arterial hypertension and its role in right ventricular hypertrophy by targeting SMURF1

    Article • Cardiovascular Research, September 2017, Oxford University Press (OUP)

    Dr Henrique Girao

  4. The Expression of Connexins and SOX2 Reflects the Plasticity of Glioma Stem-Like Cells

    Article • Translational Oncology, August 2017, Elsevier

    Dr Henrique Girao

  5. Exosomes secreted by cardiomyocytes subjected to ischaemia promote cardiac angiogenesis

    Article • Cardiovascular Research, June 2017, Oxford University Press (OUP)

    Dr Henrique Girao

  6. Characterization of phospholipid nitroxidation by LC-MS in biomimetic models and in H9c2 Myoblast using a lipidomic approach

    Article • Free Radical Biology and Medicine, May 2017, Elsevier

    Dr Henrique Girao

  7. Hyperglycemia-induced degradation of HIF-1α contributes to impaired response of cardiomyocytes to hypoxia

    Article • Revista Portuguesa de Cardiologia, May 2017, Elsevier

    Dr Henrique Girao

  8. Glioblastoma entities express subtle differences in molecular composition and response to treatment

    Article • Oncology Reports, March 2017, Spandidos Publications

    Dr Henrique Girao, Ana Cristina Gonçalves

  9. Cardiac-released extracellular vesicles can activate endothelial cells

    Article • Annals of Translational Medicine, February 2017, AME Publishing Company

    Dr Henrique Girao

  10. Targeted Approach for Proteomic Analysis of a Hidden Membrane Protein

    Article • January 2017, Springer Science + Business Media

    Dr Henrique Girao

  11. Protective Effects of Terpenes on the Cardiovascular System: Current Advances and Future Perspectives

    Article • Current Medicinal Chemistry, December 2016, Bentham Science Publishers

    Dr Henrique Girao, Jorge M. Alves-Silva

  12. The role of galectin-1 in in vitro and in vivo photodynamic therapy with a galactodendritic porphyrin

    Article • European Journal of Cancer, November 2016, Elsevier

    Dr Henrique Girao

  13. Mitochondria-Targeted Photodynamic Therapy with a Galactodendritic Chlorin to Enhance Cell Death in Resistant Bladder Cancer Cells

    Article • Bioconjugate Chemistry, October 2016, American Chemical Society (ACS)

    Dr Henrique Girao

  14. Proteostasis and SUMO in the heart

    Article • The International Journal of Biochemistry & Cell Biology, October 2016, Elsevier

    Dr Henrique Girao

  15. One small step for exosomes, one giant leap for Kawasaki disease

    Article • Revista Portuguesa de Cardiologia, May 2016, Elsevier

    Dr Henrique Girao

  16. One small step for exosomes, one giant leap for Kawasaki disease

    Article • Revista Portuguesa de Cardiologia (English Edition), May 2016, Elsevier

    Dr Henrique Girao

  17. Alteration in Phospholipidome Profile of Myoblast H9c2 Cell Line in a Model of Myocardium Starvation and Ischemia

    Article • Journal of Cellular Physiology, March 2016, Wiley

    Dr Henrique Girao

  18. Acetylated bacterial cellulose coated with urinary bladder matrix as a substrate for retinal pigment epithelium

    Article • Colloids and Surfaces B Biointerfaces, March 2016, Elsevier

    Professor Senentxu Lanceros-Mendez, Dr Henrique Girao, Dr Vitor Sencadas

  19. Presence of Cx43 in extracellular vesicles reduces the cardiotoxicity of the anti-tumour therapeutic approach with doxorubicin

    Article • Journal of Extracellular Vesicles, January 2016, Taylor & Francis

    Dr Henrique Girao

  20. Chemical characterization and cytotoxic potential of an ellagitannin-enriched fraction from Fragaria vesca leaves

    Article • Arabian Journal of Chemistry, December 2015, Elsevier

    Dr Henrique Girao, Ana Cristina Gonçalves

  21. New platinum(II)–bipyridyl corrole complexes: Synthesis, characterization and binding studies with DNA and HSA

    Article • Journal of Inorganic Biochemistry, December 2015, Elsevier

    Dr Henrique Girao

  22. Interacting Network of the Gap Junction (GJ) Protein Connexin43 (Cx43) is Modulated by Ischemia and Reperfusion in the Heart

    Article • Molecular & Cellular Proteomics, August 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Henrique Girao, Sandra I Anjo

  23. Gap junctional protein Cx43 is involved in the communication between extracellular vesicles and mammalian cells

    Article • Scientific Reports, August 2015, Nature

    Professor Joost PG Sluijter, Dr Henrique Girao

  24. The Force at the Tip - Modelling Tension and Proliferation in Sprouting Angiogenesis

    Article • PLoS Computational Biology, August 2015, PLOS

    Dr Henrique Girao

  25. To beat or not to beat: degradation of Cx43 imposes the heart rhythm: Figure 1

    Article • Biochemical Society Transactions, June 2015, Portland Press Ltd.

    Dr Henrique Girao

  26. Connexin 43 ubiquitination determines the fate of gap junctions: restrict to survive: Figure 1

    Article • Biochemical Society Transactions, June 2015, Portland Press Ltd.

    Dr Henrique Girao

  27. K63 linked ubiquitin chain formation is a signal for HIF1A degradation by Chaperone-Mediated Autophagy

    Article • Scientific Reports, May 2015, Nature

    Dr Henrique Girao

  28. Heart ischemia results in connexin43 ubiquitination localized at the intercalated discs

    Article • Biochimie, May 2015, Elsevier

    Dr Henrique Girao

  29. Ischaemia-induced autophagy leads to degradation of gap junction protein connexin43 in cardiomyocytes

    Article • Biochemical Journal, April 2015, Portland Press Ltd.

    Dr Henrique Girao

  30. Bacterial Cellulose As a Support for the Growth of Retinal Pigment Epithelium

    Article • Biomacromolecules, April 2015, American Chemical Society (ACS)

    Dr Vitor Sencadas, Professor Senentxu Lanceros-Mendez, Dr Henrique Girao

  31. Autophagy and Ubiquitination in Cardiovascular Diseases

    Article • DNA and Cell Biology, April 2015, Mary Ann Liebert Inc

    Dr Henrique Girao

  32. Tamoxifen in combination with temozolomide induce a synergistic inhibition of PKC-pan in GBM cell lines

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, April 2015, Elsevier

    Dr Henrique Girao

  33. Cholinergic stimulation with pyridostigmine protects myocardial infarcted rats against ischemic-induced arrhythmias and preserves connexin43 protein

    Article • AJP Heart and Circulatory Physiology, January 2015, American Physiological Society

    Dr Henrique Girao

  34. Synthesis, characterization and biomolecule-binding properties of novel tetra-platinum(ii)-thiopyridylporphyrins

    Article • Dalton Transactions, January 2015, Royal Society of Chemistry

    Dr Henrique Girao

  35. Bioactivity of Fragaria vesca leaves through inflammation, proteasome and autophagy modulation

    Article • Journal of Ethnopharmacology, December 2014, Elsevier

    Dr Henrique Girao

  36. AMSH-mediated deubiquitination of Cx43 regulates internalization and degradation of gap junctions

    Article • The FASEB Journal, July 2014, Federation of American Societies For Experimental Biology (FASEB)

    Dr Henrique Girao

  37. P145Degradation of gap junction protein Cx43 by autophagy in ischemic heart is determined by the triggering signal: the role of AMPK Vs Beclin1

    Article • Cardiovascular Research, June 2014, European Society of Cardiology

    Dr Henrique Girao

  38. DNAJB4 molecular chaperone distinguishes WT from mutant E-cadherin, determining their fate in vitro and in vivo

    Article • Human Molecular Genetics, November 2013, Oxford University Press (OUP)

    Dr Henrique Girao

  39. STUB1/CHIP is required for HIF1A degradation by chaperone-mediated autophagy

    Article • Autophagy, September 2013, Taylor & Francis

    Dr Henrique Girao

  40. Ubiquitin induces interference in communication: ubiquitination of cx43 leads to gap junction degradation in ischemic heart

    Article • European Heart Journal, August 2013, European Society of Cardiology

    Dr Henrique Girao

  41. To beat or not to beat: detrimental autophagy contributes to gap junctions degradation in ischemic heart

    Article • European Heart Journal, August 2013, European Society of Cardiology

    Dr Henrique Girao

  42. Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner

    Article • Molecular Biology of the Cell, April 2012, American Society for Cell Biology (ASCB)

    Dr Henrique Girao

  43. Ubiquitin-mediated internalization of connexin43 is independent of the canonical endocytic tyrosine-sorting signal

    Article • Biochemical Journal, July 2011, Portland Press Ltd.

    Dr Henrique Girao

  44. Eps15 interacts with ubiquitinated Cx43 and mediates its internalization

    Article • Experimental Cell Research, December 2009, Elsevier

    Dr Henrique Girao

  45. Actin in the endocytic pathway: From yeast to mammals

    Article • FEBS Letters, April 2008, Wiley

    Dr Henrique Girao

  46. The proteasome regulates the interaction between Cx43 and ZO-1

    Article • Journal of Cellular Biochemistry, January 2007, Wiley

    Dr Henrique Girao

  47. Subcellular Redistribution of Components of the Ubiquitin–Proteasome Pathway during Lens Differentiation and Maturation

    Article • Investigative Ophthalmology & Visual Science, April 2005, Association for Research in Vision and Ophthalmology (ARVO)

    Dr Henrique Girao

  48. High Glucose Down-regulates Intercellular Communication in Retinal Endothelial Cells by Enhancing Degradation of Connexin 43 by a Proteasome-dependent Mechanism

    Article • Journal of Biological Chemistry, April 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Henrique Girao

  49. Article • Cell Communication and Signaling, January 2004, Springer Science + Business Media

    Dr Henrique Girao

  50. Cholesterol oxides mediated changes in cytoskeletal organisation involves Rho GTPases☆☆

    Article • Experimental Cell Research, December 2003, Elsevier

    Dr Henrique Girao

  51. Lens fibers have a fully functional ubiquitin-proteasome pathway

    Article • Experimental Eye Research, May 2003, Elsevier

    Dr Henrique Girao

  52. Cholesterol may act as an antioxidant in lens membranes

    Article • Current Eye Research, January 1999, Taylor & Francis

    Dr Henrique Girao

  53. Cholesterol Oxides Accumulate in Human Cataracts

    Article • Experimental Eye Research, May 1998, Elsevier

    Dr Henrique Girao