All Stories

  1. ABC-transporter upregulation mediates resistance to the CDK7 inhibitors THZ1 and ICEC0942

    Article • Oncogene, September 2019, Springer Science + Business Media

    Dr Simak Ali

  2. Author Correction: The responses of cancer cells to PLK1 inhibitors reveal a novel protective role for p53 in maintaining centrosome separation

    Article • Scientific Reports, March 2018, Nature

    Dr Simak Ali

  3. Light-triggered enzymatic reactions in nested vesicle reactors

    Article • Nature Communications, March 2018, Nature

    Dr Simak Ali

  4. The responses of cancer cells to PLK1 inhibitors reveal a novel protective role for p53 in maintaining centrosome separation

    Article • Scientific Reports, November 2017, Nature

    Dr Simak Ali

  5. p53 controls expression of the DNA deaminase APOBEC3B to limit its potential mutagenic activity in cancer cells

    Article • Nucleic Acids Research, August 2017, Oxford University Press (OUP)

    Dr Simak Ali, Tim Fenton

  6. Oestrogen receptors and epigenetics in breast cancer aetiology and outcome

    Article • Endocrine Abstracts, October 2015, Bioscientifica

    Dr Simak Ali

  7. Noninvasive Detection of Activating Estrogen Receptor 1 (ESR1) Mutations in Estrogen Receptor-Positive Metastatic Breast Cancer

    Article • Clinical Chemistry, May 2015, AACC

    Dr Simak Ali, JIn Luo, David Guttery

  8. Engineered repressors are potent inhibitors of androgen receptor activity

    Article • Oncotarget, March 2014, Impact Journals, LLC

    Dr Simak Ali

  9. Characterisation of the androgen regulation of glycine N-methyltransferase in prostate cancer cells

    Article • August 2013, Bioscientifica

    Dr Greg N Brooke, Dr Simak Ali

  10. Abstract 4762: Anti-Nicastrin antibodies for the treatment of endocrine resistant breast cancer .

    Article • Cancer Research, April 2013, American Association for Cancer Research (AACR)

    Dr Simak Ali

  11. Development of a Novel Molecular Sensor for Imaging Estrogen Receptor-Coactivator Protein-Protein Interactions

    Article • PLoS ONE, August 2012, PLOS

    Dr Simak Ali

  12. Abstract 4205: Identification of glycine N-methyltransferase-regulated genes in prostate cancer cells

    Article • Cancer Research, April 2012, American Association for Cancer Research (AACR)

    Dr Simak Ali

  13. Differential oestrogen receptor binding is associated with clinical outcome in breast cancer

    Article • Nature, January 2012, Springer Science + Business Media

    Dr Simak Ali

  14. Antiestrogens and Their Therapeutic Applications in Breast Cancer and Other Diseases

    Article • Annual Review of Medicine, February 2011, Annual Reviews

    Dr Simak Ali

  15. The DEAD box RNA helicases p68 (Ddx5) and p72 (Ddx17): novel transcriptional co-regulators

    Article • Biochemical Society Transactions, July 2008, Portland Press Ltd.

    Dr Simak Ali

  16. Investigation of Estrogen Receptor Phosphorylation Using Phosphospecific Antibodies

    Article • Clinical Science, April 2003, Portland Press Ltd.

    Dr Simak Ali

  17. Molecular changes associated with the acquisition of oestrogen hypersensitivity in MCF-7 breast cancer cells on long-term oestrogen deprivation

    Article • The Journal of Steroid Biochemistry and Molecular Biology, August 2002, Elsevier

    Dr Simak Ali

  18. Endocrine-responsive breast cancer and strategies for combating resistance

    Article • Nature Reviews Cancer, February 2002, Springer Science + Business Media

    Dr Simak Ali

  19. Article • Journal of Mammary Gland Biology and Neoplasia, January 2000, Springer Science + Business Media

    Dr Simak Ali

  20. Phosphorylation of Human Estrogen Receptor α by Protein Kinase A Regulates Dimerization

    Article • Molecular and Cellular Biology, February 1999, ASM Journals

    Dr Simak Ali

  21. Localization and expression of the human estrogen receptor beta gene in uterine leiomyomata

    Article • Genes Chromosomes and Cancer, December 1998, Wiley

    Dr Simak Ali

  22. An important role for BRCA1 in breast cancer progression is indicated by its loss in a large proportion of non-familial breast cancers

    Article • International Journal of Cancer, August 1998, Wiley

    Dr Simak Ali

  23. Characterisation of the alleles encoding ovine ß-lactoglobulins A and B

    Article • Gene, July 1990, Elsevier

    Dr Simak Ali

  24. Characterization of the gene encoding ovine beta-lactoglobulin

    Article • Journal of Molecular Biology, February 1988, Elsevier

    Dr Simak Ali

  25. Estrogen Receptors and Anti-Estrogen Therapies

    Article • Springer Science + Business Media

    Dr Simak Ali

  26. Transcriptional Coactivators and Corepressors in Endocrine Response and Resistance in Breast Cancer

    Article • Springer Science + Business Media

    Dr Simak Ali