All Stories

  1. Liver fluke drug resistance

    Article • Trends in Parasitology, June 2016, Elsevier

    Dr Travis Beddoe

  2. The Endoplasmic Reticulum-Mitochondrion Tether ERMES Orchestrates Fungal Immune Evasion, Illuminating Inflammasome Responses to Hyphal Signals

    Article • mSphere, May 2016, ASM Journals

    Dr Travis Beddoe

  3. Thermotolerance and molecular chaperone function of an SGT1-like protein from the psychrophilic yeast, Glaciozyma antarctica

    Article • Cell Stress and Chaperones, May 2016, Springer Science + Business Media

    Dr Travis Beddoe

  4. Crystallisation of galectin-11

    Article • Acta Crystallographica Section F Structural Biology Communications, July 2015, International Union of Crystallography

    Dr Travis Beddoe

  5. Multiple ecto-nucleoside triphosphate diphosphohydrolases facilitate intracellular replication of Legionella pneumophila

    Article • Biochemical Journal, September 2014, Portland Press Ltd.

    Dr Travis Beddoe

  6. First insight into CD59-like molecules of adult Fasciola hepatica

    Article • Experimental Parasitology, September 2014, Elsevier

    Dr Travis Beddoe

  7. Evaluation of the Role of Galectins in Parasite Immunity

    Article • August 2014, Springer Science + Business Media

    Dr Travis Beddoe

  8. A structural and functional investigation of a novel protein fromMycobacterium smegmatisimplicated in mycobacterial macrophage survivability

    Article • Acta Crystallographica Section D Biological Crystallography, August 2014, International Union of Crystallography

    Dr Travis Beddoe

  9. A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells

    Article • The Journal of Experimental Medicine, July 2014, Rockefeller University Press

    Dr Travis Beddoe

  10. A mortise–tenon joint in the transmembrane domain modulates autotransporter assembly into bacterial outer membranes

    Article • Nature Communications, June 2014, Springer Science + Business Media

    Professor Anthony W Purcell, Dr Travis Beddoe, Professor Trevor Lithgow

  11. A structural characterization of the isoniazidMycobacterium tuberculosisdrug target, Rv2971, in its unliganded form

    Article • Acta Crystallographica Section F Structural Biology Communications, April 2014, International Union of Crystallography

    Dr Travis Beddoe

  12. The RNA-Dependent-RNA Polymerase, an Emerging Antiviral Drug Target for the Hendra Virus

    Article • Current Drug Targets, January 2014, Bentham Science Publishers

    Dr Travis Beddoe

  13. EcxAB Is a Founding Member of a New Family of Metalloprotease AB5 Toxins with a Hybrid Cholera-like B Subunit

    Article • Structure, November 2013, Elsevier

    Dr Travis Beddoe

  14. CD1d-lipid antigen recognition by the γδ TCR

    Article • Nature Immunology, September 2013, Nature

    Dr Travis Beddoe

  15. Structural Basis of Subtilase Cytotoxin SubAB Assembly

    Article • Journal of Biological Chemistry, August 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Travis Beddoe

  16. Cloning, expression, purification and preliminary X-ray diffraction studies of a novel AB5toxin

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, July 2013, International Union of Crystallography

    Dr Travis Beddoe

  17. Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells

    Article • Nature Immunology, July 2013, Nature

    Dr Travis Beddoe

  18. Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1

    Article • Nature Immunology, July 2013, Nature

    Dr Travis Beddoe, Samuel Forster

  19. Recognition of vitamin B metabolites by mucosal-associated invariant T cells

    Article • Nature Communications, July 2013, Nature

    Dr Travis Beddoe

  20. Efficient production of recombinant IL-21 proteins for pre-clinical studies by a two-step dilution refolding method

    Article • International Immunopharmacology, July 2013, Elsevier

    Dr Travis Beddoe

  21. Targeting of a natural killer cell receptor family by a viral immunoevasin

    Article • Nature Immunology, May 2013, Nature

    Dr Travis Beddoe

  22. Cloning, expression, purification and preliminary X-ray diffraction studies of a mycobacterial protein implicated in bacterial survival in macrophages

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, April 2013, International Union of Crystallography

    Dr Travis Beddoe

  23. Cloning, expression and crystallisation of SGT1 co-chaperone protein from Glaciozyma antarctica

    Article • January 2013, American Institute of Physics

    Dr Travis Beddoe

  24. Biased T Cell Receptor Usage Directed against Human Leukocyte Antigen DQ8-Restricted Gliadin Peptides Is Associated with Celiac Disease

    Article • Immunity, October 2012, Elsevier

    Professor Anthony W Purcell, Dr Travis Beddoe

  25. Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B

    Article • Nature, October 2011, Nature

    Dr Travis Beddoe

  26. Recognition of β-linked self glycolipids mediated by natural killer T cell antigen receptors

    Article • Nature Immunology, July 2011, Nature

    Dr Travis Beddoe

  27. How opposites attract

    Article • Immunology and Cell Biology, December 2010, Nature

    Dr Travis Beddoe

  28. The structural basis for autonomous dimerization of the pre-T-cell antigen receptor

    Article • Nature, October 2010, Springer Science + Business Media

    Professor Anthony W Purcell, Dr Travis Beddoe

  29. Structure, biological functions and applications of the AB5 toxins

    Article • Trends in Biochemical Sciences, July 2010, Elsevier

    Dr Travis Beddoe

  30. Crystal Structure and Comparative Functional Analyses of a Mycobacterium Aldo-Keto Reductase

    Article • Journal of Molecular Biology, April 2010, Elsevier

    Dr Travis Beddoe

  31. Crystal Structure of a Legionella pneumophila Ecto -Triphosphate Diphosphohydrolase, A Structural and Functional Homolog of the Eukaryotic NTPDases

    Article • Structure, February 2010, Elsevier

    Dr Travis Beddoe

  32. Structure and Function of the Oxidoreductase DsbA1 from Neisseria meningitidis

    Article • Journal of Molecular Biology, December 2009, Elsevier

    Dr Travis Beddoe, Professor Martin J Scanlon

  33. Antigen Ligation Triggers a Conformational Change within the Constant Domain of the αβ T Cell Receptor

    Article • Immunity, June 2009, Elsevier

    Professor Anthony W Purcell, Dr Travis Beddoe

  34. Crystal Structure of LipL32, the Most Abundant Surface Protein of Pathogenic Leptospira spp.

    Article • Journal of Molecular Biology, April 2009, Elsevier

    Dr Travis Beddoe

  35. Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition

    Article • The Journal of Experimental Medicine, January 2009, Rockefeller University Press

    Professor Anthony W Purcell, Dr Travis Beddoe

  36. Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin

    Article • Nature, December 2008, Springer Science + Business Media

    Professor Xi Chen, Dr Travis Beddoe

  37. Expression, purification, crystallization and preliminary X-ray characterization of a putative glycosyltransferase of the GT-A fold found in mycobacteria

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, April 2008, International Union of Crystallography

    Dr Travis Beddoe

  38. Subtle Changes in Peptide Conformation Profoundly Affect Recognition of the Non-Classical MHC Class I Molecule HLA-E by the CD94–NKG2 Natural Killer Cell Receptors

    Article • Journal of Molecular Biology, April 2008, Elsevier

    Dr Travis Beddoe

  39. A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR

    Article • The Journal of Experimental Medicine, March 2008, Rockefeller University Press

    Dr Travis Beddoe

  40. CD94-NKG2A recognition of human leukocyte antigen (HLA)-E bound to an HLA class I leader sequence

    Article • The Journal of Experimental Medicine, March 2008, Rockefeller University Press

    Dr Travis Beddoe

  41. The Heterodimeric Assembly of the CD94-NKG2 Receptor Family and Implications for Human Leukocyte Antigen-E Recognition

    Article • Immunity, December 2007, Elsevier

    Dr Travis Beddoe

  42. A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule

    Article • Nature Immunology, January 2007, Springer Science + Business Media

    Professor Anthony W Purcell, Dr Travis Beddoe

  43. AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP

    Article • Nature, October 2006, Nature

    Dr Travis Beddoe

  44. Tracking the Unfolding Pathway of a Multirepeat Protein via Tryptophan Scanning

    Article • Journal of Biological Chemistry, June 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Travis Beddoe

  45. Hijacking of a Substrate-binding Protein Scaffold for use in Mycobacterial Cell Wall Biosynthesis

    Article • Journal of Molecular Biology, June 2006, Elsevier

    Dr Travis Beddoe

  46. A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition

    Article • The Journal of Experimental Medicine, February 2006, Rockefeller University Press

    Dr Travis Beddoe

  47. Structural basis for a major histocompatibility complex class Ib–restricted T cell response

    Article • Nature Immunology, February 2006, Nature

    Dr Travis Beddoe

  48. The 2.0 Å Crystal Structure of a Pocilloporin at pH 3.5: The Structural Basis for the Linkage Between Color Transition and Halide Binding

    Article • Photochemistry and Photobiology, January 2006, Wiley

    Dr Travis Beddoe

  49. Expression, purification, crystallization and preliminary X-ray diffraction analysis of an essential lipoprotein implicated in cell-wall biosynthesis inMycobacteria

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, November 2005, International Union of Crystallography

    Dr Travis Beddoe

  50. T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I–bound peptide

    Article • Nature Immunology, September 2005, Springer Science + Business Media

    Professor Anthony W Purcell, Dr Travis Beddoe

  51. High Resolution Structures of Highly Bulged Viral Epitopes Bound to Major Histocompatibility Complex Class I

    Article • Journal of Biological Chemistry, April 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Anthony W Purcell, Dr Travis Beddoe

  52. The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition

    Article • Nature Immunology, January 2005, Springer Science + Business Media

    Professor Anthony W Purcell, Dr Travis Beddoe

  53. Natural HLA Class I Polymorphism Controls the Pathway of Antigen Presentation and Susceptibility to Viral Evasion

    Article • The Journal of Experimental Medicine, June 2004, Rockefeller University Press

    Professor Anthony W Purcell, Dr Travis Beddoe

  54. The 2.2 Å Crystal Structure of a Pocilloporin Pigment Reveals a Nonplanar Chromophore Conformation

    Article • Structure, March 2003, Elsevier

    Dr Travis Beddoe

  55. The production, purification and crystallization of a pocilloporin pigment from a reef-forming coral

    Article • Acta Crystallographica Section D Biological Crystallography, February 2003, International Union of Crystallography

    Dr Travis Beddoe

  56. Delivery of nascent polypeptides to the mitochondrial surface

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, September 2002, Elsevier

    Dr Travis Beddoe, Professor Trevor Lithgow

  57. The nascent polypeptide-associated complex (NAC) promotes interaction of ribosomes with the mitochondrial surface in vivo

    Article • FEBS Letters, March 2002, Wiley

    Dr Travis Beddoe, Professor Trevor Lithgow

  58. The mitochondrial protein targeting suppressor (mts1) mutation maps to the mRNA-binding domain of Npl3p and affects translation on cytoplasmic polysomes

    Article • Molecular Microbiology, January 2002, Wiley

    Dr Travis Beddoe, Professor Trevor Lithgow

  59. Ribosome binding to the surface of mitochondria: mechanisms and consequences

    Article • Biochemical Society Transactions, October 2000, Portland Press Ltd.

    Dr Travis Beddoe

  60. The protein encoded by the MFT1 gene is a targeting factor for mitochondrial precursor proteins, and not a core ribosomal protein

    Article • FEBS Letters, April 1997, Wiley

    Dr Travis Beddoe, Professor Trevor Lithgow