All Stories

  1. Longitudinal single-cell RNA sequencing of patient-derived primary cells reveals drug-induced infidelity in stem cell hierarchy

    Article • Nature Communications, November 2018, Springer Science + Business Media

    Dr Ankur Sharma

  2. Phenotype-driven precision oncology as a guide for clinical decisions one patient at a time

    Article • Nature Communications, September 2017, Springer Science + Business Media

    Dr Ankur Sharma

  3. SpDamID: Marking DNA Bound by Protein Complexes Identifies Notch-Dimer Responsive Enhancers

    Article • Molecular Cell, August 2015, Elsevier

    Dr Ankur Sharma

  4. A novel Monoclonal Antibody against Notch1 Targets Leukemia-associated Mutant Notch1 and Depletes Therapy Resistant Cancer Stem Cells in Solid Tumors

    Article • Scientific Reports, June 2015, Nature

    Dr Ankur Sharma

  5. Coordinate Hyperactivation of Notch1 and Ras/MAPK Pathways Correlates with Poor Patient Survival: Novel Therapeutic Strategy for Aggressive Breast Cancers

    Article • Molecular Cancer Therapeutics, September 2014, American Association for Cancer Research (AACR)

    Dr Ankur Sharma

  6. Abstract 231: Conformation-specific monoclonal antibodies against Notch1 target aberrant Notch1 signaling in cancer stem cells.

    Article • Cancer Research, April 2013, American Association for Cancer Research (AACR)

    Dr Ankur Sharma

  7. Antibodies against the extracellular domain of human Notch1 receptor reveal the critical role of epidermal-growth-factor-like repeats 25–26in ligand binding and receptor activation

    Article • Biochemical Journal, January 2013, Portland Press Ltd.

    Dr Ankur Sharma

  8. A Monoclonal Antibody against Human Notch1 Ligand-Binding Domain Depletes Subpopulation of Putative Breast Cancer Stem-like Cells

    Article • Molecular Cancer Therapeutics, November 2011, American Association for Cancer Research (AACR)

    Dr Ankur Sharma