All Stories

  1. The predictive power of the microbiome exceeds that of genome-wide association studies in the discrimination of complex human disease

    Article • January 2020, Cold Spring Harbor Laboratory Press

    Dr Aleksandar D Kostic

  2. The Landscape of Genetic Content in the Gut and Oral Human Microbiome

    Article • Cell Host & Microbe, August 2019, Elsevier

    Dr Aleksandar D Kostic

  3. Predictive metabolomic profiling of microbial communities using amplicon or metagenomic sequences

    Article • Nature Communications, July 2019, Springer Science + Business Media

    Dr Aleksandar D Kostic

  4. Meta-omics analysis of elite athletes identifies a performance-enhancing microbe that functions via lactate metabolism

    Article • Nature Reports Stem Cells, June 2019, Springer Science + Business Media

    Dr Aleksandar D Kostic

  5. Bacteroides-Derived Sphingolipids Are Critical for Maintaining Intestinal Homeostasis and Symbiosis

    Article • Cell Host & Microbe, May 2019, Elsevier

    Dr Aleksandar D Kostic

  6. A perfect storm: Genetics and anticommensal antibodies shore up type 1 diabetes

    Article • Science Immunology, February 2019, American Association for the Advancement of Science

    Dr Aleksandar D Kostic

  7. The Crohn’s disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response

    Article • eLife, January 2019, eLife

    Dr Aleksandar D Kostic

  8. Understanding the growing epidemic of type 2 diabetes in the Hispanic population living in the United States

    Article • Diabetes/Metabolism Research and Reviews, December 2018, Wiley

    Dr Aleksandar D Kostic

  9. Correction for Zhao et al., Intestinal virome changes precede autoimmunity in type I diabetes-susceptible children

    Article • Proceedings of the National Academy of Sciences, November 2018, Proceedings of the National Academy of Sciences

    Dr Aleksandar D Kostic

  10. Fusobacterium nucleatum in Colorectal Cancer Relates to Immune Response Differentially by Tumor Microsatellite Instability Status

    Article • Cancer Immunology Research, September 2018, American Association for Cancer Research (AACR)

    Dr Aleksandar D Kostic

  11. Diet, Genetics, and the Gut Microbiome Drive Dynamic Changes in Plasma Metabolites

    Article • Cell Reports, March 2018, Elsevier

    Dr Aleksandar D Kostic

  12. Assessment of the cPAS-based BGISEQ-500 platform for metagenomic sequencing

    Article • GigaScience, December 2017, Oxford University Press (OUP)

    Dr Aleksandar D Kostic

  13. Aether: leveraging linear programming for optimal cloud computing in genomics

    Article • Bioinformatics, December 2017, Oxford University Press (OUP)

    Dr Aleksandar D Kostic

  14. Aether: Leveraging Linear Programming For Optimal Cloud Computing In Genomics

    Article • July 2017, Cold Spring Harbor Laboratory Press

    Dr Aleksandar D Kostic

  15. Intestinal virome changes precede autoimmunity in type I diabetes-susceptible children

    Article • Proceedings of the National Academy of Sciences, July 2017, Proceedings of the National Academy of Sciences

    Dr Aleksandar D Kostic

  16. Association of Dietary Patterns With Risk of Colorectal Cancer Subtypes Classified by Fusobacterium nucleatum in Tumor Tissue

    Article • JAMA Oncology, July 2017, American Medical Association (AMA)

    Dr Aleksandar D Kostic

  17. Gut Microbiota: Small Molecules Modulate Host Cellular Functions

    Article • Current Biology, April 2017, Elsevier

    Dr Aleksandar D Kostic

  18. A Microbiome Foundation for the Study of Crohn’s Disease

    Article • Cell Host & Microbe, March 2017, Elsevier

    Dr Aleksandar D Kostic

  19. Emerging Concepts and Technologies for the Discovery of Microorganisms Involved in Human Disease

    Article • Annual Review of Pathology Mechanisms of Disease, January 2017, Annual Reviews

    Dr Aleksandar D Kostic

  20. Fusobacterium nucleatum in Colorectal Carcinoma Tissue According to Tumor Location

    Article • Clinical and Translational Gastroenterology, November 2016, Nature

    Dr Aleksandar D Kostic

  21. Dysbiosis, inflammation, and response to treatment: a longitudinal study of pediatric subjects with newly diagnosed inflammatory bowel disease

    Article • Genome Medicine, July 2016, Springer Science + Business Media

    Dr Aleksandar D Kostic

  22. The Dynamics of the Human Infant Gut Microbiome in Development and in Progression toward Type 1 Diabetes

    Article • Cell Host & Microbe, July 2016, Elsevier

    Dr Aleksandar D Kostic

  23. Research Highlights

    Article • Transplantation, July 2016, Wolters Kluwer Health

    Dr Aleksandar D Kostic

  24. Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans

    Article • Cell, June 2016, Elsevier

    Dr Aleksandar D Kostic

  25. Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans

    Article • Cell, May 2016, Elsevier

    Dr Aleksandar D Kostic

  26. Fusobacterium nucleatum in colorectal carcinoma tissue and patient prognosis

    Article • Gut, August 2015, BMJ

    Dr Aleksandar D Kostic

  27. Fusobacterium nucleatumand T Cells in Colorectal Carcinoma

    Article • JAMA Oncology, August 2015, American Medical Association (AMA)

    Dr Aleksandar D Kostic

  28. An Integrative View of Microbiome-Host Interactions in Inflammatory Bowel Diseases

    Article • Cell Host & Microbe, May 2015, Elsevier

    Dr Aleksandar D Kostic

  29. The Dynamics of the Human Infant Gut Microbiome in Development and in Progression toward Type 1 Diabetes

    Article • Cell Host & Microbe, February 2015, Elsevier

    Dr Aleksandar D Kostic

  30. Inflammatory Bowel Disease as a Model for Translating the Microbiome

    Article • Immunity, June 2014, Elsevier

    Dr Aleksandar D Kostic

  31. The Microbiome in Inflammatory Bowel Disease: Current Status and the Future Ahead

    Article • Gastroenterology, May 2014, Elsevier

    Dr Aleksandar D Kostic

  32. The Treatment-Naive Microbiome in New-Onset Crohn’s Disease

    Article • Cell Host & Microbe, March 2014, Elsevier

    Dr Aleksandar D Kostic

  33. Human Genome-Wide RNAi Screen Identifies an Essential Role for Inositol Pyrophosphates in Type-I Interferon Response

    Article • PLoS Pathogens, February 2014, PLOS

    Dr Aleksandar D Kostic

  34. Microbes and Inflammation in Colorectal Cancer

    Article • Cancer Immunology Research, September 2013, American Association for Cancer Research (AACR)

    Dr Aleksandar D Kostic

  35. Sequence-Based Discovery ofBradyrhizobium entericain Cord Colitis Syndrome

    Article • New England Journal of Medicine, August 2013, New England Journal of Medicine (NEJM/MMS)

    Dr Aleksandar D Kostic, Dr Francisco M Marty

  36. Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment

    Article • Cell Host & Microbe, August 2013, Elsevier

    Dr Aleksandar D Kostic

  37. Exploring host-microbiota interactions in animal models and humans

    Article • Genes & Development, April 2013, Cold Spring Harbor Laboratory Press

    Dr Aleksandar D Kostic

  38. Prognostically relevant gene signatures of high-grade serous ovarian carcinoma

    Article • Journal of Clinical Investigation, December 2012, American Society for Clinical Investigation

    Dr Aleksandar D Kostic

  39. Keystone microbiome meeting 2012: a mountain top experience

    Article • EMBO Reports, May 2012, EMBO

    Dr Aleksandar D Kostic

  40. Genomic analysis identifies association of Fusobacterium with colorectal carcinoma

    Article • Genome Research, October 2011, Cold Spring Harbor Laboratory Press

    Dr Aleksandar D Kostic

  41. The Mutational Landscape of Head and Neck Squamous Cell Carcinoma

    Article • Science, July 2011, American Association for the Advancement of Science

    Dr Jorge Melendez-Zajgla, Dr Aleksandar D Kostic, Dr Alfredo Hidalgo-Miranda

  42. PathSeq: software to identify or discover microbes by deep sequencing of human tissue

    Article • Nature Biotechnology, May 2011, Nature

    Dr Aleksandar D Kostic

  43. The TPR-containing domain within Est1 homologs exhibits species-specific roles in telomerase interaction and telomere length homeostasis

    Article • BMC Molecular Biology, January 2011, Springer Science + Business Media

    Dr Aleksandar D Kostic