All Stories

  1. Trisomy 21 Represses Cilia Formation and Function
  2. Autophagy Inhibition Mediates Apoptosis Sensitization in Cancer Therapy by Relieving FOXO3a Turnover
  3. Mechanisms of transcriptional regulation by p53
  4. CDK8 Kinase Activity Promotes Glycolysis
  5. Trisomy 21 causes changes in the circulating proteome indicative of chronic autoinflammation
  6. Identification of a core TP53 transcriptional program with highly distributed tumor suppressive activity
  7. Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia
  8. Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase
  9. Trisomy 21 consistently activates the interferon response
  10. A signature for success
  11. Human ACAP2 is a homolog ofC. elegansCNT-1 that promotes apoptosis in cancer cells
  12. p53 Family Members Regulate Phenotypic Response to Aurora Kinase A Inhibition in Triple-Negative Breast Cancer
  13. Caspase-activated phosphoinositide binding by CNT-1 promotes apoptosis by inhibiting the AKT pathway
  14. ATM regulates cell fate choice upon p53 activation by modulating mitochondrial turnover and ROS levels
  15. Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms
  16. Inhibition of Telomerase Recruitment and Cancer Cell Death
  17. ATM and MET kinases are synthetic lethal with nongenotoxic activation of p53
  18. The p53 circuit board
  19. A Core Complex of CPSF73, CPSF100, and Symplekin May Form Two Different Cleavage Factors for Processing of Poly(A) and Histone mRNAs
  20. Knockdown of SLBP results in nuclear retention of histone mRNA
  21. Studies of the 5′ Exonuclease and Endonuclease Activities of CPSF-73 in Histone Pre-mRNA Processing
  22. Nuclear Autoantigenic Sperm Protein (NASP), a Linker Histone Chaperone That Is Required for Cell Proliferation