All Stories

  1. Designing DNA nanodevices for compatibility with the immune system of higher organisms
  2. The cytoskeleton in cell-autonomous immunity: structural determinants of host defence
  3. Antimicrobial inflammasomes: unified signalling against diverse bacterial pathogens
  4. IFN-Inducible GTPases in Host Cell Defense
  5. IFN-  Elicits Macrophage Autophagy via the p38 MAPK Signaling Pathway
  6. GBP5 Promotes NLRP3 Inflammasome Assembly and Immunity in Mammals
  7. A Family of IFN- -Inducible 65-kD GTPases Protects Against Bacterial Infection
  8. The Evolution of Guanylyl Cyclases as Multidomain Proteins: Conserved Features of Kinase-Cyclase Domain Fusions
  9. Characterization of an Evolutionarily Conserved Metallophosphoesterase That Is Expressed in the Fetal Brain and Associated with the WAGR Syndrome
  10. Cyclic AMP in Mycobacteria: Characterization and Functional Role of the Rv1647 Ortholog in Mycobacterium smegmatis
  11. Emerging themes in IFN-γ-induced macrophage immunity by the p47 and p65 GTPase families
  12. Structural and Biochemical Analysis of the Rv0805 Cyclic Nucleotide Phosphodiesterase from Mycobacterium tuberculosis
  13. New messages from old messengers: cAMP and mycobacteria
  14. Evolution of a Protein-Folding Machine: Genomic and Evolutionary Analyses Reveal Three Lineages of the Archaeal hsp70(dnaK) Gene
  15. Mycobacterial adenylyl cyclases: Biochemical diversity and structural plasticity
  16. A Structural Basis for the Role of Nucleotide Specifying Residues in Regulating the Oligomerization of the Rv1625c Adenylyl Cyclase from M.tuberculosis
  17. The Kinase Homology Domain of Receptor Guanylyl Cyclase C:  ATP Binding and Identification of an Adenine Nucleotide Sensitive Site †
  18. The Rv0805 Gene from Mycobacterium tuberculosis Encodes a 3‘,5‘-Cyclic Nucleotide Phosphodiesterase:  Biochemical and Mutational Analysis †
  19. An adenylyl cyclase pseudogene in Mycobacterium tuberculosis has a functional ortholog in Mycobacterium avium
  20. Characterization of phylogenetically distant members of the adenylate cyclase family from mycobacteria: Rv1647 from Mycobacterium tuberculosis and its orthologue ML1399 from M. leprae
  21. Tyrphostins Are Inhibitors of Guanylyl and Adenylyl Cyclases †
  22. Class III nucleotide cyclases in bacteria and archaebacteria: lineage-specific expansion of adenylyl cyclases and a dearth of guanylyl cyclases
  23. Purification, crystallization and preliminary X-ray diffraction analysis of the catalytic domain of adenylyl cyclase Rv1625c fromMycobacterium tuberculosis
  24. A Survey of Nucleotide Cyclases in Actinobacteria: Unique Domain Organization and Expansion of the Class III Cyclase Family in Mycobacterium tuberculosis
  25. Site-directed mutagenesis using a single mutagenic oligonucleotide and DpnI digestion of template DNA
  26. Mutational analysis of the Mycobacterium tuberculosis Rv1625c adenylyl cyclase: residues that confer nucleotide specificity contribute to dimerization
  27. The ascent of nucleotide cyclases: conservation and evolution of a theme
  28. His kinase or mine? Histidine kinases through evolution