Contact

All Stories

  1. The C-Type Lectin Receptor DC-SIGN Has an Anti-Inflammatory Role in Human M(IL-4) Macrophages in Response to Mycobacterium tuberculosis

    Article • Frontiers in Immunology, June 2018, Frontiers

    Dr. Geanncarlo Lugo-Villarino

  2. Podosomes, But Not the Maturation Status, Determine the Protease-Dependent 3D Migration in Human Dendritic Cells

    Article • Frontiers in Immunology, April 2018, Frontiers

    Dr. Geanncarlo Lugo-Villarino

  3. Formation of Foamy Macrophages by Tuberculous Pleural Effusions Is Triggered by the Interleukin-10/Signal Transducer and Activator of Transcription 3 Axis through ACAT Upregulation

    Article • Frontiers in Immunology, March 2018, Frontiers

    Dr. Geanncarlo Lugo-Villarino

  4. Type-2 diabetes alters the basal phenotype of human macrophages and diminishes their capacity to respond, internalise, and control Mycobacterium tuberculosis

    Article • Memórias do Instituto Oswaldo Cruz, February 2018, FapUNIFESP (SciELO)

    Dr. Geanncarlo Lugo-Villarino

  5. Tunneling Nanotubes: Intimate Communication between Myeloid Cells

    Article • Frontiers in Immunology, January 2018, Frontiers

    Dr. Geanncarlo Lugo-Villarino

  6. C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells

    Article • Proceedings of the National Academy of Sciences, January 2017, Proceedings of the National Academy of Sciences

    Dr. Geanncarlo Lugo-Villarino

  7. Role of Cathepsins in Mycobacterium tuberculosis Survival in Human Macrophages

    Article • Scientific Reports, August 2016, Nature

    Professor Elsa Anes, Dr. Geanncarlo Lugo-Villarino

  8. Tuberculosis is associated with expansion of a motile, permissive and immunomodulatory CD16+ monocyte population via the IL-10/STAT3 axis

    Article • Cell Research, October 2015, Nature

    Dr. Geanncarlo Lugo-Villarino

  9. Collectin CL-LK Is a Novel Soluble Pattern Recognition Receptor for Mycobacterium tuberculosis

    Article • PLoS ONE, July 2015, PLOS

    Dr. Geanncarlo Lugo-Villarino

  10. Diverging biological roles among human monocyte subsets in the context of tuberculosis infection

    Article • Clinical Science, April 2015, Portland Press Ltd.

    Dr. Geanncarlo Lugo-Villarino

  11. SIGNing a symbiotic treaty with gut microbiota

    Article • The EMBO Journal, March 2015, EMBO

    Dr. Geanncarlo Lugo-Villarino

  12. Pyroptosis of resident macrophages differentially orchestrates inflammatory responses toStaphylococcus aureusin resistant and susceptible mice

    Article • European Journal of Immunology, January 2015, Wiley

    Dr Guillaume Tabouret, Dr. Geanncarlo Lugo-Villarino

  13. Playing hide-and-seek with host macrophages through the use of mycobacterial cell envelope phthiocerol dimycocerosates and phenolic glycolipids

    Article • Frontiers in Cellular and Infection Microbiology, December 2014, Frontiers

    Dr. Geanncarlo Lugo-Villarino

  14. Manipulation of the Mononuclear Phagocyte System by Mycobacterium tuberculosis

    Article • Cold Spring Harbor Perspectives in Medicine, August 2014, Cold Spring Harbor Laboratory Press

    Dr. Geanncarlo Lugo-Villarino

  15. Of Clots and Granulomas: Platelets are New Players in Immunity to Tuberculosis

    Article • The Journal of Infectious Diseases, July 2014, Oxford University Press (OUP)

    Dr. Geanncarlo Lugo-Villarino

  16. An efficient siRNA-mediated gene silencing in primary human monocytes, dendritic cells and macrophages

    Article • Immunology and Cell Biology, June 2014, Nature

    Dr. Geanncarlo Lugo-Villarino

  17. A genomic portrait of the genetic architecture and regulatory impact of microRNA expression in response to infection

    Article • Genome Research, January 2014, Cold Spring Harbor Laboratory Press

    Dr. Geanncarlo Lugo-Villarino

  18. Mycobacterium tuberculosis nitrogen assimilation and host colonization require aspartate

    Article • Nature Methods, September 2013, Nature

    Dr. Geanncarlo Lugo-Villarino

  19. The C-type Lectin Receptors Dectin-1, MR, and SIGNR3 Contribute Both Positively and Negatively to the Macrophage Response to Leishmania infantum

    Article • Immunity, May 2013, Elsevier

    Dr. Geanncarlo Lugo-Villarino

  20. Dressed not to kill: CD16+monocytes impair immune defence against tuberculosis

    Article • European Journal of Immunology, February 2013, Wiley

    Dr. Geanncarlo Lugo-Villarino

  21. Actin-binding protein regulation by microRNAs as a novel microbial strategy to modulate phagocytosis by host cells: the case of N-Wasp and miR-142-3p

    Article • Frontiers in Cellular and Infection Microbiology, January 2013, Frontiers

    Professor Elsa Anes, Dr. Geanncarlo Lugo-Villarino

  22. Emerging Trends in the Formation and Function of Tuberculosis Granulomas

    Article • Frontiers in Immunology, January 2013, Frontiers

    Dr. Geanncarlo Lugo-Villarino

  23. Metallobiology of host–pathogen interactions: an intoxicating new insight

    Article • Trends in Microbiology, March 2012, Elsevier

    Dr. Geanncarlo Lugo-Villarino

  24. Small Molecule-Mediated Activation of the Integrin CD11b/CD18 Reduces Inflammatory Disease

    Article • Science Signaling, September 2011, American Association for the Advancement of Science

    Dr. Geanncarlo Lugo-Villarino

  25. Mycobacterial P1-Type ATPases Mediate Resistance to Zinc Poisoning in Human Macrophages

    Article • Cell Host & Microbe, September 2011, Elsevier

    Dr. Geanncarlo Lugo-Villarino

  26. C-type lectins with a sweet spot forMycobacterium tuberculosis

    Article • European Journal of Microbiology and Immunology, March 2011, Akademiai Kiado

    Dr. Geanncarlo Lugo-Villarino

  27. Editorial: How to play tag? DC-SIGN shows the way!

    Article • Journal of Leukocyte Biology, February 2011, Society for Leukocyte Biology

    Dr. Geanncarlo Lugo-Villarino

  28. Macrophage polarization: convergence point targeted by Mycobacterium tuberculosis and HIV

    Article • Frontiers in Immunology, January 2011, Frontiers

    Dr. Geanncarlo Lugo-Villarino

  29. Identification of dendritic antigen-presenting cells in the zebrafish

    Article • Proceedings of the National Academy of Sciences, August 2010, Proceedings of the National Academy of Sciences

    Dr. Geanncarlo Lugo-Villarino

  30. Eosinophils in the zebrafish: prospective isolation, characterization, and eosinophilia induction by helminth determinants

    Article • Blood, August 2010, American Society of Hematology

    Dr. Geanncarlo Lugo-Villarino

  31. T-Bet Plays a Key Role in NK-Mediated Control of Melanoma Metastatic Disease

    Article • The Journal of Immunology, June 2008, The American Association of Immunologists

    Dr. Geanncarlo Lugo-Villarino

  32. Communicable Ulcerative Colitis Induced by T-bet Deficiency in the Innate Immune System

    Article • Cell, October 2007, Elsevier

    Dr. Geanncarlo Lugo-Villarino

  33. Cutting Edge: STAT1 and T-bet Play Distinct Roles in Determining Outcome of Visceral Leishmaniasis Caused by Leishmania donovani

    Article • The Journal of Immunology, June 2006, The American Association of Immunologists

    Dr. Geanncarlo Lugo-Villarino

  34. Transcription factor T-bet regulates inflammatory arthritis through its function in dendritic cells

    Article • Journal of Clinical Investigation, January 2006, American Society for Clinical Investigation

    Dr. Geanncarlo Lugo-Villarino

  35. The adjuvant activity of CpG DNA requires T-bet expression in dendritic cells

    Article • Proceedings of the National Academy of Sciences, August 2005, Proceedings of the National Academy of Sciences

    Dr. Geanncarlo Lugo-Villarino

  36. T-bet is required for optimal production of IFN-γ and antigen-specific T cell activation by dendritic cells

    Article • Proceedings of the National Academy of Sciences, June 2003, Proceedings of the National Academy of Sciences

    Dr. Geanncarlo Lugo-Villarino

  37. A Mammalian Homolog of Drosophila schnurri, KRC, Regulates TNF Receptor-Driven Responses and Interacts with TRAF2

    Article • Molecular Cell, January 2002, Elsevier

    Dr. Geanncarlo Lugo-Villarino

  38. Individual VH promoters vary in strength, but the frequency of rearrangement of those VH genes does not correlate with promoter strength nor enhancer-independence

    Article • Molecular Immunology, January 2000, Elsevier

    Dr. Geanncarlo Lugo-Villarino

  39. Sequence of the Spacer in the Recombination Signal Sequence Affects V(D)J Rearrangement Frequency and Correlates with Nonrandom Vκ Usage In Vivo

    Article • The Journal of Experimental Medicine, May 1998, Rockefeller University Press

    Dr. Geanncarlo Lugo-Villarino

  40. A defective Vkappa A2 allele in Navajos which may play a role in increased susceptibility to haemophilus influenzae type b disease.

    Article • Journal of Clinical Investigation, May 1996, American Society for Clinical Investigation

    Dr. Geanncarlo Lugo-Villarino