All Stories

  1. An open RNA-Seq data analysis pipeline tutorial with an example of reprocessing data from a recent Zika virus study
  2. Drug-induced adverse events prediction with the LINCS L1000 data
  3. Abstract B1-25: Data integration for illuminating the druggable genome
  4. Principle Angle Enrichment Analysis (PAEA): Dimensionally reduced multivariate gene set enrichment analysis tool
  5. A Systems Approach Identifies Essential FOXO3 Functions at Key Steps of Terminal Erythropoiesis
  6. An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin
  7. Abstract SY10-04: Histone tail alterations in cellular senescence
  8. Morphine Regulated Synaptic Networks Revealed by Integrated Proteomics and Network Analysis
  9. Dynamics of the discovery process of protein-protein interactions from low content studies
  10. GEO2Enrichr: browser extension and server app to extract gene sets from GEO and analyze them for biological functions: Fig. 1.
  11. Histone H3.3 and its proteolytically processed form drive a cellular senescence programme
  12. A blueprint of cell identity
  13. Lean Big Data integration in systems biology and systems pharmacology
  14. Construction and Validation of a Regulatory Network for Pluripotency and Self-Renewal of Mouse Embryonic Stem Cells
  15. The characteristic direction: a geometrical approach to identify differentially expressed genes
  16. ELK1 Transcription Factor Linked to Dysregulated Striatal Mu Opioid Receptor Signaling Network and OPRM1 Polymorphism in Human Heroin Abusers
  17. Induction of a Hemogenic Program in Mouse Fibroblasts
  18. Expression of HIV transgene aggravates kidney injury in diabetic mice
  19. Transforming Growth Factor β Signaling Controls Activities of Human Intestinal CD8+T Suppressor Cells
  20. Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool
  21. Systems pharmacology meets predictive, preventive, personalized and participatory medicine
  22. Quantitative Approaches to Model Pluripotency and Differentiation in Stem Cells
  23. Biological and Quantitative Models for Stem Cell Self-Renewal and Differentiation
  24. ChEA2: Gene-Set Libraries from ChIP-X Experiments to Decode the Transcription Regulome
  25. Colliding Dynamical Complex Network Models: Biological Attractors versus Attractors from Material Physics
  26. Sox2 in the Dermal Papilla Niche Controls Hair Growth by Fine-Tuning BMP Signaling in Differentiating Hair Shaft Progenitors
  27. Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity
  28. Connecting clusters of patient to drug responses of cell lines to suggest personalized therapeutics for breast cancer
  29. Network- and attribute-based classifiers can prioritize genes and pathways for autism spectrum disorders and intellectual disability
  30. A systems approach identifies HIPK2 as a key regulator of kidney fibrosis
  31. Receptor Heteromerization Expands the Repertoire of Cannabinoid Signaling in Rodent Neurons
  32. New Frontiers of Network Analysis in Systems Biology
  33. Network Pharmacology to Aid the Drug Discovery Process
  34. Systems biology of kidney diseases
  35. Sets2Networks: network inference from repeated observations of sets
  36. Genes2FANs: connecting genes through functional association networks
  37. Recovering Protein-Protein and Domain-Domain Interactions from Aggregation of IP-MS Proteomics of Coregulator Complexes
  38. Oct4 links multiple epigenetic pathways to the pluripotency network
  39. Chronic Morphine Alters the Presynaptic Protein Profile: Identification of Novel Molecular Targets Using Proteomics and Network Analysis
  40. Sig2BioPAX: Java tool for converting flat files to BioPAX Level 3 format
  41. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
  42. Protein Kinase Target Discovery From Genome-Wide Messenger RNA Expression Profiling
  43. Microdynamics and Criticality of Adaptive Regulatory Networks
  44. Toward a complete in silico , multi-layered embryonic stem cell regulatory network
  45. Lists2Networks: Integrated analysis of gene/protein lists
  46. Inferring the Sign of Kinase-Substrate Interactions by Combining Quantitative Phosphoproteomics with a Literature-Based Mammalian Kinome Network
  47. SVM classifier to predict genes important for self-renewal and pluripotency of mouse embryonic stem cells
  48. Systems-level dynamic analyses of fate change in murine embryonic stem cells
  49. Systems biology of stem cell fate and cellular reprogramming
  50. Systems approach to explore components and interactions in the presynapse
  51. PubMedAlertMe—Standalone Windows-based PubMed SDI software application
  52. Functions of Bifans in Context of Multiple Regulatory Motifs in Signaling Networks
  53. Multiple Kinases and System Robustness: A Link Between Cdc37 and Genome Integrity
  54. Connecting Seed Lists of Mammalian Proteins Using Steiner Trees
  55. Functional atlas of the integrin adhesome
  56. Genes2Networks: Connecting Lists of Proteins by Using Background Literature-based Mammalian Networks
  57. Network analysis of FDA approved drugs and their targets
  58. Genes2Networks: connecting lists of gene symbols using mammalian protein interactions databases
  59. The cognitive phenotype of Down syndrome: Insights from intracellular network analysis
  60. The cognitive phenotype of Down syndrome: Insights from intracellular network analysis
  61. Topology of resultant networks shaped by evolutionary pressure
  62. Toward Predictive Models of Mammalian Cells