All Stories

  1. Competence-induced protein Ccs4 facilitates pneumococcal invasion into brain tissue and virulence in meningitis

    Article • Virulence, September 2018, Taylor & Francis

    Masaya Yamaguchi, Dr Masanobu Nakata

  2. Zinc metalloproteinase ZmpC suppresses experimental pneumococcal meningitis by inhibiting bacterial invasion of central nervous systems

    Article • Virulence, June 2017, Taylor & Francis

    Dr Masanobu Nakata, Masaya Yamaguchi

  3. Evolutionary inactivation of a sialidase in group B Streptococcus

    Article • Scientific Reports, June 2016, Nature

    Dr Masanobu Nakata

  4. Streptococcus oralis Induces Lysosomal Impairment of Macrophages via Bacterial Hydrogen Peroxide

    Article • Infection and Immunity, April 2016, ASM Journals

    Dr Masanobu Nakata

  5. Group A Streptococcus exploits human plasminogen for bacterial translocation across epithelial barrier via tricellular tight junctions

    Article • Scientific Reports, January 2016, Nature

    Dr Masanobu Nakata

  6. Cell Wall-Anchored Nuclease of Streptococcus sanguinis Contributes to Escape from Neutrophil Extracellular Trap-Mediated Bacteriocidal Activity

    Article • PLoS ONE, August 2014, PLOS

    Dr Masanobu Nakata

  7. Hydrogen Peroxide Contributes to the Epithelial Cell Death Induced by the Oral Mitis Group of Streptococci

    Article • PLoS ONE, January 2014, PLOS

    Dr Masanobu Nakata

  8. Hydrogen Peroxide Produced by Oral Streptococci Induces Macrophage Cell Death

    Article • PLoS ONE, May 2013, PLOS

    Dr Masanobu Nakata

  9. Cysteine Proteinase from Streptococcus pyogenes Enables Evasion of Innate Immunity via Degradation of Complement Factors

    Article • Journal of Biological Chemistry, April 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Masanobu Nakata

  10. Group A Streptococcal Cysteine Protease Cleaves Epithelial Junctions and Contributes to Bacterial Translocation

    Article • Journal of Biological Chemistry, March 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Masanobu Nakata

  11. Involvement of T6 Pili in Biofilm Formation by Serotype M6 Streptococcus pyogenes

    Article • Journal of Bacteriology, December 2011, ASM Journals

    Dr Masanobu Nakata

  12. S-Carboxymethylcysteine inhibits adherence of Streptococcus pneumoniae to human alveolar epithelial cells

    Article • Journal of Medical Microbiology, September 2011, Society for General Microbiology

    Dr Masanobu Nakata

  13. Streptococcus sanguinis induces foam cell formation and cell death of macrophages in association with production of reactive oxygen species

    Article • FEMS Microbiology Letters, September 2011, Oxford University Press (OUP)

    Dr Masanobu Nakata

  14. Assembly Mechanism of FCT Region Type 1 Pili in Serotype M6 Streptococcus pyogenes

    Article • Journal of Biological Chemistry, August 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Masanobu Nakata

  15. Pili of oral Streptococcus sanguinis bind to salivary amylase and promote the biofilm formation

    Article • Microbial Pathogenesis, March 2011, Elsevier

    Dr Masanobu Nakata

  16. Streptolysin S Contributes to Group A Streptococcal Translocation across an Epithelial Barrier

    Article • Journal of Biological Chemistry, November 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Masanobu Nakata

  17. Pili of oral Streptococcus sanguinis bind to fibronectin and contribute to cell adhesion

    Article • Biochemical and Biophysical Research Communications, January 2010, Elsevier

    Dr Masanobu Nakata

  18. M-protein and other intrinsic virulence factors of Streptococcus pyogenes are encoded on an ancient pathogenicity island

    Article • BMC Genomics, January 2009, Springer Science + Business Media

    Dr Masanobu Nakata

  19. Mode of Expression and Functional Characterization of FCT-3 Pilus Region-Encoded Proteins in Streptococcus pyogenes Serotype M49

    Article • Infection and Immunity, October 2008, ASM Journals

    Dr Masanobu Nakata

  20. PlyC, a novel bacteriophage lysin for compartment- dependent proteomics of group A streptococci

    Article • PROTEOMICS, January 2008, Wiley

    Dr Masanobu Nakata

  21. Streptococcus pyogenes serotype-dependent and independent changes in infected HEp-2 epithelial cells

    Article • The ISME Journal, October 2007, Nature

    Dr Masanobu Nakata

  22. The Streptococcus pyogenes Serotype M49 Nra-Ralp3 Transcriptional Regulatory Network and Its Control of Virulence Factor Expression from the Novel eno ralp3 epf sagA Pathogenicity Region

    Article • Infection and Immunity, September 2007, ASM Journals

    Dr Masanobu Nakata

  23. Streptococcus pyogenes Collagen Type I-binding Cpa Surface Protein: EXPRESSION PROFILE, BINDING CHARACTERISTICS, BIOLOGICAL FUNCTIONS, AND POTENTIAL CLINICAL IMPACT

    Article • Journal of Biological Chemistry, July 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Masanobu Nakata

  24. MsmR, a specific positive regulator of the Streptococcus pyogenes FCT pathogenicity region and cytolysin-mediated translocation system genes

    Article • Molecular Microbiology, June 2005, Wiley

    Dr Masanobu Nakata

  25. Global epithelial cell transcriptional responses reveal Streptococcus pyogenes Fas regulator activity association with bacterial aggressiveness

    Article • Cellular Microbiology, June 2005, Wiley

    Dr Masanobu Nakata

  26. Autophagy Defends Cells Against Invading Group A Streptococcus

    Article • Science, November 2004, American Association for the Advancement of Science

    Dr Masanobu Nakata

  27. Transcriptome analysis and gene expression profiles of early apoptosis-related genes in Streptococcus pyogenes-infected epithelial cells

    Article • Cellular Microbiology, October 2004, Wiley

    Dr Masanobu Nakata

  28. Streptococcus pyogenes Fibronectin-binding Protein F2: EXPRESSION PROFILE, BINDING CHARACTERISTICS, AND IMPACT ON EUKARYOTIC CELL INTERACTIONS

    Article • Journal of Biological Chemistry, January 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Masanobu Nakata

  29. Molecular Characterization of a Novel Fibronectin-binding Protein of Streptococcus pyogenesStrains Isolated from Toxic Shock-like Syndrome Patients

    Article • Journal of Biological Chemistry, September 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Masanobu Nakata

  30. Infection and pathogenesis of a murine strain of Escherichia coli with genetically introduced Shiga toxin type I operon in conventional mice

    Article • Microbial Pathogenesis, August 2002, Elsevier

    Dr Masanobu Nakata

  31. Regulated expression of the Shiga toxin B gene induces apoptosis in mammalian fibroblastic cells

    Article • Molecular Microbiology, March 2002, Wiley

    Dr Masanobu Nakata

  32. Cytochromec-mediated caspase-9 activation triggers apoptosis inStreptococcus pyogenes-infected epithelial cells

    Article • Cellular Microbiology, June 2001, Wiley

    Dr Masanobu Nakata