All Stories

  1. Proteogenomics 101: a primer on database search strategies
  2. Quality control of variant peptides identified through proteogenomics- catching the (un)usual suspects
  3. Downregulation of peripheral PTGS2/COX-2 in response to valproate treatment in patients with epilepsy
  4. Fusion transcripts in normal human cortex increase with age and show distinct genomic features for single cells and tissues
  5. Investigating Coronary Artery Disease methylome through targeted bisulfite sequencing
  6. Host cholesterol dependent activation of VapC12 toxin enriches persister population duringMycobacterium tuberculosisinfection
  7. Telomere repeat–binding factor 2 binds extensively to extra-telomeric G-quadruplexes and regulates the epigenetic status of several gene promoters
  8. The complete chloroplast genome of Dendrobium nobile, an endangered medicinal orchid from north-east India and its comparison with related Dendrobium species
  9. Cellular responses to proteostasis perturbations reveal non-optimal feedback in chaperone networks
  10. Quantitative Lipid Droplet Proteomics Reveals Mycobacterium tuberculosis Induced Alterations in Macrophage Response to Infection
  11. VitiVar: A locus specific database of vitiligo associated genes and variations
  12. The Complete Chloroplast Genome of Dendrobium nobile, an endangered medicinal orchid from Northeast India and its comparison with related chloroplast genomes of Dendrobium species
  13. Adipocyte Model of Mycobacterium tuberculosis Infection Reveals Differential Availability of Iron to Bacilli in the Lipid-Rich Caseous Environment
  14. Western Indian Rural Gut Microbial Diversity in Extreme Prakriti Endo-Phenotypes Reveals Signature Microbes
  15. Recapitulation of Ayurveda constitution types by machine learning of phenotypic traits
  16. Comparative Genomics of Host–Symbiont and Free-Living Oceanobacillus Species
  17. Data Intensive Genome Level Analysis for Identifying Novel, Non-Toxic Drug Targets for Multi Drug Resistant Mycobacterium tuberculosis
  18. Ayurgenomics for stratified medicine: TRISUTRA consortium initiative across ethnically and geographically diverse Indian populations
  19. Choosing an Optimal Database for Protein Identification from Tandem Mass Spectrometry Data
  20. Integrating transcriptome and proteome profiling: Strategies and applications
  21. Leveraging Structural Hierarchy for Scalable Network Comparison
  22. Proteogenomic Tools and Approaches to Explore Protein Coding Landscapes of Eukaryotic Genomes
  23. Proteogenomics of rare taxonomic phyla: A prospective treasure trove of protein coding genes
  24. Integrated Transcriptomic-Proteomic Analysis Using a Proteogenomic Workflow Refines Rat Genome Annotation
  25. Polyketide Quinones Are Alternate Intermediate Electron Carriers during Mycobacterial Respiration in Oxygen-Deficient Niches
  26. Accurate Classification of Biological Data Using Ensembles
  27. Expression profiling of lymph nodes in tuberculosis patients reveal inflammatory milieu at site of infection
  28. Probing the Missing Human Proteome: A Computational Perspective
  29. Transcriptome and venom proteome of the box jellyfish Chironex fleckeri
  30. Extensive Copy Number Variations in Admixed Indian Population of African Ancestry: Potential Involvement in Adaptation
  31. Discovery of rare protein-coding genes in model methylotrophMethylobacterium extorquensAM1
  32. How do eubacterial organisms manage aggregation-prone proteome?
  33. Gene-Rich Large Deletions Are Overrepresented in POAG Patients of Indian and Caucasian Origins
  34. Selection of relevant features from amino acids enables development of robust classifiers
  35. Proteogenomic Analysis of Bradyrhizobium japonicum USDA110 Using Genosuite, an Automated Multi-algorithmic Pipeline
  36. Novel mutations in typical and atypical genetic loci through exome sequencing in autosomal recessive cerebellar ataxia families
  37. ProteoStats—a library for estimating false discovery rates in proteomics pipelines
  38. Exosome-enclosed microRNAs in exhaled breath hold potential for biomarker discovery in patients with pulmonary diseases
  39. Electrostatic Mis-Interactions Cause Overexpression Toxicity of Proteins in E. coli
  40. Learning from Decoys to Improve the Sensitivity and Specificity of Proteomics Database Search Results
  41. Crowd Sourcing a New Paradigm for Interactome Driven Drug Target Identification in Mycobacterium tuberculosis
  42. Knowledge engineering for health: A new discipline required to bridge the “ICT gap” between research and healthcare
  43. Location of disorder in coiled coilproteins is influenced by its biological role and subcellular localization: a GO-based study on human proteome
  44. A Systematic Analysis of Eluted Fraction of Plasma Post Immunoaffinity Depletion: Implications in Biomarker Discovery
  45. Recent Admixture in an Indian Population of African Ancestry
  46. Spectrum of large copy number variations in 26 diverse Indian populations: potential involvement in phenotypic diversity
  47. Open source drug discovery– A new paradigm of collaborative research in tuberculosis drug development
  48. Recent Admixture in an Indian Population of African Ancestry
  49. MassWiz: A Novel Scoring Algorithm with Target-Decoy Based Analysis Pipeline for Tandem Mass Spectrometry
  50. A web server for predicting inhibitors against bacterial target GlmU protein
  51. IGVBrowser-a genomic variation resource from diverse Indian populations
  52. The phenotype and genotype experiment object model (PaGE-OM): a robust data structure for information related to DNA variation
  53. Unraveling the potential of intrinsically disordered proteins as drug targets: application to Mycobacterium tuberculosis
  54. HGVbaseG2P: a central genetic association database
  55. Genetic landscape of the people of India: a canvas for disease gene exploration
  56. Intrinsic disorder in yeast transcriptional regulatory network
  57. Dynamic α‐helices: Conformations that do not conform
  58. Role of intrinsic disorder in transient interactions of hub proteins
  59. Intrinsic unstructuredness and abundance of PEST motifs in eukaryotic proteomes
  60. The Indian Genome Variation database (IGVdb): a project overview
  61. Conformational Analysis of Invariant Peptide Sequences in Bacterial Genomes
  62. In silico characterization of the INO80 subfamily of SWI2/SNF2 chromatin remodeling proteins
  63. Comparative analysis of protein unfoldedness in human housekeeping and non-housekeeping proteins
  64. CoPS: Comprehensive Peptide Signature Database
  65. Recognition and analysis of protein-coding genes in severe acute respiratory syndrome associated coronavirus
  66. Role of histidine interruption in mitigating the pathological effects of long polyglutamine stretches in SCA1: A molecular approach
  67. Origin and Instability of GAA Repeats: Insights from Alu Elements
  68. Spectrum of β‐thalassemia mutations and their association with allelic sequence polymorphisms at the β‐globin gene cluster in an eastern Indian population
  69. Association of CAG repeat loci on chromosome 22 with schizophrenia and bipolar disorder
  70. Intramolecular i-motif Structure at Acidic pH for Progressive Myoclonus Epilepsy (EPM1) Repeat d(CCCCGCCCCGCG)n
  71. Progressive Myoclonus Epilepsy [EPM1] repeat d(CCCCGCCCCGCG)nforms folded hairpin structures at physiological pH