All Stories

  1. Molecular Chaperones as Polypeptide Unfolding Enzymes

    Article • Annual Review of Biochemistry, June 2016, Annual Reviews

    Dr Andrija Finka, Prof Pierre Goloubinoff

  2. Multi-layered molecular mechanisms of polypeptide holding, unfolding and disaggregation by HSP70/HSP110 chaperones

    Article • Frontiers in Molecular Biosciences, June 2015, Frontiers

    Dr Andrija Finka, Prof Pierre Goloubinoff

  3. Quantitative proteomics of heat-treated human cells show an across-the-board mild depletion of housekeeping proteins to massively accumulate few HSPs

    Article • Cell Stress and Chaperones, April 2015, Springer Science + Business Media

    Dr Andrija Finka, Prof Pierre Goloubinoff

  4. Recent and future grand challenges in protein folding, misfolding, and degradation

    Article • Frontiers in Molecular Biosciences, March 2014, Frontiers

    Prof Pierre Goloubinoff

  5. Physical Interaction between Bacterial Heat Shock Protein (Hsp) 90 and Hsp70 Chaperones Mediates Their Cooperative Action to Refold Denatured Proteins

    Article • Journal of Biological Chemistry, January 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Pierre Goloubinoff

  6. Hsp110 Is a Bona Fide Chaperone Using ATP to Unfold Stable Misfolded Polypeptides and Reciprocally Collaborate with Hsp70 to Solubilize Protein Aggregates

    Article • Journal of Biological Chemistry, June 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Pierre Goloubinoff

  7. Molecular chaperones as enzymes that catalytically unfold misfolded polypeptides

    Article • FEBS Letters, May 2013, Wiley

    Prof Pierre Goloubinoff

  8. Biophysical Characterization of Two Different Stable Misfolded Monomeric Polypeptides That Are Chaperone-Amenable Substrates

    Article • Journal of Molecular Biology, April 2013, Elsevier

    Prof Pierre Goloubinoff

  9. The Membrane-Associated Transient Receptor Potential Vanilloid Channel Is the Central Heat Shock Receptor Controlling the Cellular Heat Shock Response in Epithelial Cells

    Article • PLoS ONE, February 2013, PLOS

    Prof Pierre Goloubinoff

  10. Heat shock response in photosynthetic organisms: Membrane and lipid connections

    Article • Progress in Lipid Research, July 2012, Elsevier

    Prof Pierre Goloubinoff

  11. How do plants feel the heat?

    Article • Trends in Biochemical Sciences, March 2012, Elsevier

    Dr Andrija Finka, Prof Pierre Goloubinoff

  12. Protein folding: Chaperoning protein evolution

    Article • Nature Methods, February 2012, Nature

    Prof Pierre Goloubinoff

  13. Non-native Proteins as Newly-Identified Targets of Heavy Metals and Metalloids

    Article • January 2011, Springer Science + Business Media

    Prof Pierre Goloubinoff

  14. Molecular Chaperones and Associated Cellular Clearance Mechanisms against Toxic Protein Conformers in Parkinson’s Disease

    Article • Neurodegenerative Diseases, January 2011, Karger Publishers

    Prof Pierre Goloubinoff

  15. Heat perception and signalling in plants: a tortuous path to thermotolerance

    Article • New Phytologist, December 2010, Wiley

    Dr Andrija Finka, Prof Pierre Goloubinoff

  16. Membrane lipid composition affects plant heat sensing and modulates Ca2+-dependent heat shock response

    Article • Plant Signaling & Behavior, December 2010, Taylor & Francis

    Dr Andrija Finka, Prof Pierre Goloubinoff

  17. Meta-analysis of heat- and chemically upregulated chaperone genes in plant and human cells

    Article • Cell Stress and Chaperones, August 2010, Springer Science + Business Media

    Dr Andrija Finka, Prof Pierre Goloubinoff

  18. Disaggregating Chaperones: An Unfolding Story

    Article • Current Protein and Peptide Science, October 2009, Bentham Science Publishers

    Prof Pierre Goloubinoff

  19. The Heat Shock Response in Moss Plants Is Regulated by Specific Calcium-Permeable Channels in the Plasma Membrane

    Article • The Plant Cell, September 2009, American Society of Plant Biologists (ASPB)

    Dr Andrija Finka, Prof Pierre Goloubinoff

  20. Enhanced expression of 70-kilodalton heat shock protein limits cell division in a sepsis-induced model of acute respiratory distress syndrome*

    Article • Critical Care Medicine, January 2008, Wolters Kluwer Health

    Prof Pierre Goloubinoff

  21. Enhanced heat shock protein 70 expression alters proteasomal degradation of IκB kinase in experimental acute respiratory distress syndrome*

    Article • Critical Care Medicine, September 2007, Wolters Kluwer Health

    Prof Pierre Goloubinoff

  22. Activation of the heat shock response in plants by chlorophenols: transgenic Physcomitrella patens as a sensitive biosensor for organic pollutants

    Article • Plant Cell & Environment, June 2007, Wiley

    Prof Pierre Goloubinoff

  23. In vivovisualization of F-actin structures during the development of the mossPhyscomitrella patens

    Article • New Phytologist, January 2007, Wiley

    Dr Andrija Finka, Prof Pierre Goloubinoff

  24. Chaperones and Proteases: Cellular Fold-Controlling Factors of Proteins in Neurodegenerative Diseases and Aging

    Article • Journal of Molecular Neuroscience, January 2006, Springer Science + Business Media

    Prof Pierre Goloubinoff

  25. Controlled Expression of Recombinant Proteins in Physcomitrella patens by a Conditional Heat-shock Promoter: a Tool for Plant Research and Biotechnology

    Article • Plant Molecular Biology, November 2005, Springer Science + Business Media

    Dr Andrija Finka, Prof Pierre Goloubinoff

  26. A gene trap Dissociation insertion line, associated with a RING-H2 finger gene, shows tissue specific and developmental regulated expression of the gene in Arabidopsis

    Article • Gene, May 2002, Elsevier

    Prof Pierre Goloubinoff

  27. Chemical Chaperones Regulate Molecular Chaperones in Vitro and in Cells under Combined Salt and Heat Stresses

    Article • Journal of Biological Chemistry, August 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Pierre Goloubinoff

  28. Synechocystis HSP17 is an amphitropic protein that stabilizes heat-stressed membranes and binds denatured proteins for subsequent chaperone-mediated refolding

    Article • Proceedings of the National Academy of Sciences, February 2001, Proceedings of the National Academy of Sciences

    Prof Pierre Goloubinoff

  29. Temperature-Controlled Activity of DnaK−DnaJ−GrpE Chaperones:  Protein-Folding Arrest and Recovery during and after Heat Shock Depends on the Substrate Protein and the GrpE Concentration †

    Article • Biochemistry, July 1998, American Chemical Society (ACS)

    Prof Pierre Goloubinoff

  30. The Small Heat-shock Protein IbpB from Escherichia coli Stabilizes Stress-denatured Proteins for Subsequent Refolding by a Multichaperone Network

    Article • Journal of Biological Chemistry, May 1998, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Pierre Goloubinoff

  31. [22] Structural analysis of GroE chaperonin complexes using chemical cross-linking

    Article • January 1998, Elsevier

    Prof Pierre Goloubinoff

  32. GroES binding regulates GroEL chaperonin activity under heat shock

    Article • FEBS Letters, April 1997, Wiley

    Prof Pierre Goloubinoff

  33. Evidence for a lipochaperonin: Association of active proteinfolding GroESL oligomers with lipids can stabilize membranes under heat shock conditions

    Article • Proceedings of the National Academy of Sciences, March 1997, Proceedings of the National Academy of Sciences

    Prof Pierre Goloubinoff

  34. Effect of Free and ATP-bound Magnesium and Manganese Ions on the ATPase Activity of Chaperonin GroEL14

    Article • Biochemistry, January 1995, American Chemical Society (ACS)

    Prof Pierre Goloubinoff

  35. Effect of divalent cations on the molecular structure of the GroEL oligomer. [Erratum to document cited in CA120:317960]

    Article • Biochemistry, October 1994, American Chemical Society (ACS)

    Prof Pierre Goloubinoff

  36. Characterization of a functional GroEL14(GroES7)2 chaperonin hetero-oligomer

    Article • Science, July 1994, American Association for the Advancement of Science

    Prof Pierre Goloubinoff

  37. Effect of Divalent Cations on the Molecular Structure of the GroEL Oligomer

    Article • Biochemistry, May 1994, American Chemical Society (ACS)

    Prof Pierre Goloubinoff

  38. The Cellular Functions of Chaperonins

    Article • January 1990, Springer Science + Business Media

    Prof Pierre Goloubinoff

  39. Reconstitution of active dimeric ribulose bisphosphate carboxylase from an unfolded state depends on two chaperonin proteins and Mg-ATP

    Article • Nature, December 1989, Nature

    Prof Pierre Goloubinoff

  40. GroE heat-shock proteins promote assembly of foreign prokaryotic ribulose bisphosphate carboxylase oligomers in Escherichia coli

    Article • Nature, January 1989, Nature

    Prof Pierre Goloubinoff

  41. Molecular Crime and Cellular Punishment

    Article • Springer Science + Business Media

    Prof Pierre Goloubinoff

  42. Mechanisms of Active Solubilization of Stable Protein Aggregates by Molecular Chaperones

    Article • Springer Science + Business Media

    Prof Pierre Goloubinoff