All Stories

  1. Bench-Stable Transfer Reagent Facilitates the Generation of Trifluoromethyl-sulfonimidamides
  2. Identifying Small-Molecule Binding Sites for Epigenetic Proteins at Domain-Domain Interfaces
  3. Discovery of a novel allosteric inhibitor scaffold for polyadenosine-diphosphate-ribose polymerase 14 (PARP14) macrodomain 2
  4. Mild, calcium catalysed Beckmann rearrangements
  5. Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7
  6. Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7
  7. Selective Targeting of Bromodomains of the Bromodomain-PHD Fingers Family Impairs Osteoclast Differentiation
  8. Design of a Chemical Probe for the Bromodomain and Plant Homeodomain Finger-Containing (BRPF) Family of Proteins
  9. Development of chemical probes for the bromodomains of BRD7 and BRD9