Dr Antonio AC Cilia

All Stories

1. 
   Effect of the replacement of the o-methoxyphenyl moiety with nitrogen-containing aromatic rings within N-phenyl-piperazine and phenoxy-ethylamine-based 1,3-dioxo/oxathio/dithiolanes as α1 and 5-HT1A receptor ligands

   Article • Results in Chemistry, January 2022, Elsevier

   Dr Antonio AC Cilia

2. 
   1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity

   Article • European Journal of Medicinal Chemistry, August 2019, Elsevier

   Dr Antonio AC Cilia

3. 
   Synthesis and biological evaluation of 1,3-dioxolane-based 5-HT1A receptor agonists for CNS disorders and neuropathic pain

   Article • Future Medicinal Chemistry, September 2018, Future Science

   Silvia Franchini, Dr Antonio AC Cilia

4. 
   Quinazoline based α 1 -adrenoreceptor antagonists with potent antiproliferative activity in human prostate cancer cell lines

   Article • European Journal of Medicinal Chemistry, August 2017, Elsevier

   Dr Antonio AC Cilia

5. 
   Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists

   Article • European Journal of Medicinal Chemistry, January 2017, Elsevier

   Dr Antonio AC Cilia

6. 
   Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives

   Article • European Journal of Medicinal Chemistry, April 2016, Elsevier

   Dr Antonio AC Cilia

7. 
   Insights into the interaction of negative allosteric modulators with the metabotropic glutamate receptor 5: Discovery and computational modeling of a new series of ligands with nanomolar affinity

   Article • Bioorganic & Medicinal Chemistry, July 2015, Elsevier

   Dr Antonio AC Cilia

8. 
   Enantiomeric resolution of [(2,2-diphenyl-1,3-dioxolan-4-yl)methyl](2-phenoxyethyl)amine, a potent α1and 5-HT1Areceptor ligand: an in vitro and computational study

   Article • MedChemComm, January 2015, Royal Society of Chemistry

   Dr Antonio AC Cilia

9. 
   Structure–affinity/activity relationships of 1,4-dioxa-spiro[4.5]decane based ligands at α1 and 5-HT1A receptors

   Article • European Journal of Medicinal Chemistry, November 2014, Elsevier

   Dr Antonio AC Cilia

10. 
    Synthesis, Biological Evaluation, and Docking Studies of Tetrahydrofuran- Cyclopentanone- and Cyclopentanol-Based Ligands Acting at Adrenergic α1- and Serotonine 5-HT1AReceptors

    Article • Journal of Medicinal Chemistry, January 2012, American Chemical Society (ACS)

    Dr Antonio AC Cilia

11. 
    1,3-Dioxolane-based ligands incorporating a lactam or imide moiety: Structure–affinity/activity relationship at α1-adrenoceptor subtypes and at 5-HT1A receptors

    Article • European Journal of Medicinal Chemistry, September 2010, Elsevier

    Dr Antonio AC Cilia

12. 
    Discovery of a new series of 5-HT1A receptor agonists

    Article • Bioorganic & Medicinal Chemistry Letters, March 2010, Elsevier

    Dr Antonio AC Cilia

13. 
    (2,2-Diphenyl-[1,3]oxathiolan-5-ylmethyl)-(3-phenyl-propyl)-amine: a Potent and Selective 5-HT1AReceptor Agonist

    Article • ChemMedChem, February 2009, Wiley

    Dr Antonio AC Cilia

14. 
    5-(2-Pyrrolidinyl)oxazolidinones and 2-(2-pyrrolidinyl)benzodioxanes: Synthesis of all the stereoisomers and α4β2 nicotinic affinity

    Article • Bioorganic & Medicinal Chemistry Letters, February 2009, Elsevier

    Dr Antonio AC Cilia

15. 
    Corrigendum to “Synthesis and α4β2 nicotinic affinity of unichiral 5-(2-pyrrolidinyl)oxazolidinones and 2-(2-pyrrolidinyl)benzodioxanes” [Bioorg. Med. Chem. Lett. 16 (2006) 5610–5615]

    Article • Bioorganic & Medicinal Chemistry Letters, December 2007, Elsevier

    Dr Antonio AC Cilia

16. 
    Synthesis and α4β2 nicotinic affinity of unichiral 5-(2-pyrrolidinyl)oxazolidinones and 2-(2-pyrrolidinyl)benzodioxanes

    Article • Bioorganic & Medicinal Chemistry Letters, November 2006, Elsevier

    Dr Antonio AC Cilia

17. 
    Effect of different 5-hydroxytryptamine receptor subtype antagonists on the micturition reflex in rats

    Article • BJU International, February 2001, Wiley

    Dr Antonio AC Cilia