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  1. Mitochondrial DNA – novel mechanisms of kidney damage and potential biomarker

    Article • Current Opinion in Nephrology & Hypertension, September 2023, Wolters Kluwer Health

    Dr Afshan N Malik

  2. Stress‐dependent macromolecular crowding in the mitochondrial matrix

    Article • The EMBO Journal, February 2023, EMBO

    Dr Afshan N Malik

  3. Preclinical evidence for mitochondrial DNA as a potential blood biomarker for chemotherapy-induced peripheral neuropathy

    Article • PLoS ONE, January 2022, PLOS

    Dr Afshan N Malik

  4. Mitochondria, oxidative stress and nonalcoholic fatty liver disease: A complex relationship

    Article • European Journal of Clinical Investigation, June 2021, Wiley

    Dr Afshan N Malik

  5. Optimizing beta cell function through mesenchymal stromal cell-mediated mitochondria transfer

    Article • Stem Cells, January 2020, Wiley

    Dr Afshan N Malik

  6. Regional mitochondrial DNA and cell-type changes in post-mortem brains of non-diabetic Alzheimer’s disease are not present in diabetic Alzheimer’s disease

    Article • Scientific Reports, August 2019, Springer Science + Business Media

    Dr Afshan N Malik, Dr Hannah Rosa

  7. Reduced mitochondrial lipid oxidation leads to fat accumulation in myosteatosis

    Article • The FASEB Journal, July 2019, Federation of American Societies For Experimental Biology (FASEB)

    Dr Afshan N Malik

  8. Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

    Article • The American Journal of Human Genetics, January 2019, Elsevier

    Dr Afshan N Malik

  9. Mitochondrial DNA as a Potential Translational Biomarker of Mitochondrial Dysfunction in Drug-Induced Toxicity Studies

    Article • February 2018, Wiley

    Dr Afshan N Malik

  10. Potential Mechanisms of Mitochondrial DNA Mediated Acquired Mitochondrial Disease

    Article • January 2018, Springer Science + Business Media

    Dr Afshan N Malik, Dr Hannah Rosa

  11. Mitochondrial genes are altered in blood early in Alzheimer's disease

    Article • Neurobiology of Aging, May 2017, Elsevier

    Dr Afshan N Malik

  12. Hyperglycemia induced damage to mitochondrial respiration in renal mesangial and tubular cells: Implications for diabetic nephropathy

    Article • Redox Biology, December 2016, Elsevier

    Dr Afshan N Malik

  13. Accurate quantification of mouse mitochondrial DNA without co-amplification of nuclear mitochondrial insertion sequences

    Article • Mitochondrion, July 2016, Elsevier

    Dr Afshan N Malik

  14. Altered circulating mitochondrial DNA and increased inflammation in patients with diabetic retinopathy

    Article • Diabetes Research and Clinical Practice, December 2015, Elsevier

    Dr Afshan N Malik

  15. Equilibrative nucleoside transporter 3 depletion in β-cells impairs mitochondrial function and promotes apoptosis: Relationship to pigmented hypertrichotic dermatosis with insulin-dependent diabetes

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, October 2015, Elsevier

    Dr Afshan N Malik

  16. Altered Mitochondrial Function, Mitochondrial DNA and Reduced Metabolic Flexibility in Patients With Diabetic Nephropathy

    Article • EBioMedicine, June 2015, Elsevier

    Dr Afshan N Malik

  17. Understanding the Implications of Mitochondrial DNA Variation in the Health of Black Southern African Populations: The 2014 Workshop

    Article • Human Mutation, April 2015, Wiley

    Dr Afshan N Malik

  18. Accurate Measurement of Circulating Mitochondrial DNA Content from Human Blood Samples Using Real-Time Quantitative PCR

    Article • January 2015, Springer Science + Business Media

    Dr Afshan N Malik

  19. Is mitochondrial DNA content a potential biomarker of mitochondrial dysfunction?

    Article • Mitochondrion, September 2013, Elsevier

    Dr Afshan N Malik

  20. Nop-7-associated 2 (NSA2), a candidate gene for diabetic nephropathy, is involved in the TGFβ1 pathway

    Article • The International Journal of Biochemistry & Cell Biology, March 2013, Elsevier

    Dr Afshan N Malik

  21. Elevated levels of renal and circulating Nop-7-associated 2 (NSA2) in rat and mouse models of diabetes, in mesangial cells in vitro and in patients with diabetic nephropathy

    Article • Diabetologia, November 2011, Springer Science + Business Media

    Dr Afshan N Malik

  22. Mitochondrial DNA as a non-invasive biomarker: Accurate quantification using real time quantitative PCR without co-amplification of pseudogenes and dilution bias

    Article • Biochemical and Biophysical Research Communications, August 2011, Elsevier

    Dr Afshan N Malik

  23. Hyperglycemia induces elevated expression of thyroid hormone binding protein in vivo in kidney and heart and in vitro in mesangial cells

    Article • Biochemical and Biophysical Research Communications, January 2010, Elsevier

    Dr Afshan N Malik

  24. Increased peripheral blood mitochondrial DNA in type 2 diabetic patients with nephropathy

    Article • Diabetes Research and Clinical Practice, November 2009, Elsevier

    Dr Afshan N Malik

  25. Glucose regulation of CDK7, a putative thiol related gene, in experimental diabetic nephropathy

    Article • Biochemical and Biophysical Research Communications, May 2007, Elsevier

    Dr Afshan N Malik

  26. Glucose regulation of β-defensin-1 mRNA in human renal cells

    Article • Biochemical and Biophysical Research Communications, February 2007, Elsevier

    Dr Afshan N Malik

  27. Scaphoid views: a need for standardisation

    Article • Annals of The Royal College of Surgeons of England, May 2004, Royal College of Surgeons of England

    Dr Afshan N Malik

  28. Elevated levels of beta defensin-1 mRNA in diabetic kidneys of GK rats

    Article • Biochemical and Biophysical Research Communications, October 2003, Elsevier

    Dr Afshan N Malik

  29. Isolation of Diabetes-Associated Kidney Genes Using Differential Display

    Article • Biochemical and Biophysical Research Communications, March 1997, Elsevier

    Dr Afshan N Malik

  30. Molecular characterisation of theXenopus laevis chaperonin geneCctg

    Article • Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, November 1996, Elsevier

    Dr Afshan N Malik

  31. Drosophila melanogaster P1 genomic clone DS05563 contains the chaperonin-encoding gene Cctg

    Article • Gene, June 1996, Elsevier

    Dr Afshan N Malik

  32. Cloning and nucleotide sequence of a full length cDNA encoding ribosomal protein L27 from human fetal kidney

    Article • Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, April 1994, Elsevier

    Dr Afshan N Malik

  33. Parathyroid hormone-related peptide: Expression in fetal and neonatal development

    Article • The Journal of Pathology, July 1992, Wiley

    Dr Afshan N Malik

  34. Molecular genetics of Pseudomonas syringae pathovar pisi: plasmid involvement in cultivar-specific incompatibility

    Article • Journal of General Microbiology, September 1991, Society for General Microbiology

    Dr Afshan N Malik

  35. A simple high yield method for the preparation of lambda gt10 DNA suitable for subcloning, amplification and direct sequencing

    Article • Nucleic Acids Research, January 1990, Oxford University Press (OUP)

    Dr Afshan N Malik