All Stories

  1. Helix-loop-helix peptide foldamers and their use in the construction of hydrolase mimetics

    Article • Bioorganic Chemistry, July 2018, Elsevier

    Łukasz Berlicki

  2. Frontispiece: Sequence Engineering to Control the Helix Handedness of Peptide Foldamers

    Article • Chemistry - A European Journal, October 2017, Wiley

    Łukasz Berlicki

  3. Sequence Engineering to Control the Helix Handedness of Peptide Foldamers

    Article • Chemistry - A European Journal, October 2017, Wiley

    Łukasz Berlicki

  4. Bioactive Macrocyclic Inhibitors of the PD-1/PD-L1 Immune Checkpoint

    Article • Angewandte Chemie International Edition, September 2017, Wiley

    Łukasz Berlicki, PhD Grzegorz Dubin

  5. Discovery of new leads against Mycobacterium tuberculosis using scaffold hopping and shape based similarity

    Article • Bioorganic & Medicinal Chemistry, September 2017, Elsevier

    Łukasz Berlicki, Dr Elvis A F Martis

  6. Aminophosphinates against Helicobacter pylori ureolysis—Biochemical and whole-cell inhibition characteristics

    Article • PLoS ONE, August 2017, PLOS

    Łukasz Berlicki, Prof. Joanna Wietrzyk

  7. Novel organophosphorus scaffolds of urease inhibitors obtained by substitution of Morita-Baylis-Hillman adducts with phosphorus nucleophiles

    Article • European Journal of Medicinal Chemistry, June 2017, Elsevier

    Łukasz Berlicki

  8. Potent covalent inhibitors of bacterial urease identified by activity-reactivity profiling

    Article • Bioorganic & Medicinal Chemistry Letters, March 2017, Elsevier

    Łukasz Berlicki, Prof. Joanna Wietrzyk

  9. Controlling the Helix Handedness of ααβ-Peptide Foldamers through Sequence Shifting

    Article • Angewandte Chemie International Edition, January 2017, Wiley

    Łukasz Berlicki

  10. Controlling the Helix Handedness of ααβ-Peptide Foldamers through Sequence Shifting

    Article • Angewandte Chemie International Edition, January 2017, Wiley

    Łukasz Berlicki

  11. 1,2-Benzisoselenazol-3(2H)-one Derivatives As a New Class of Bacterial Urease Inhibitors

    Article • Journal of Medicinal Chemistry, September 2016, American Chemical Society (ACS)

    Łukasz Berlicki

  12. A structural insight into the P1S1 binding mode of diaminoethylphosphonic and phosphinic acids, selective inhibitors of alanine aminopeptidases

    Article • European Journal of Medicinal Chemistry, July 2016, Elsevier

    Łukasz Berlicki

  13. Phytotoxicity of aminobisphosphonates targeting bothδ1-pyrroline-5-carboxylate reductase and glutamine synthetase

    Article • Pest Management Science, May 2016, Wiley

    Łukasz Berlicki

  14. Peptide-based inhibitors of protein–protein interactions

    Article • Bioorganic & Medicinal Chemistry Letters, February 2016, Elsevier

    Łukasz Berlicki

  15. Zwitterionic Phosphorylated Quinines as Chiral Solvating Agents for NMR Spectroscopy

    Article • Chirality, August 2015, Wiley

    Łukasz Berlicki

  16. Bisphosphonic acids as effective inhibitors of Mycobacterium tuberculosis glutamine synthetase

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, August 2015, Taylor & Francis

    Łukasz Berlicki

  17. Bis(aminomethyl)phosphinic Acid, a Highly Promising Scaffold for the Development of Bacterial Urease Inhibitors

    Article • ACS Medicinal Chemistry Letters, February 2015, American Chemical Society (ACS)

    Łukasz Berlicki

  18. Peptides Containing β-Amino Acid Patterns: Challenges and Successes in Medicinal Chemistry

    Article • Journal of Medicinal Chemistry, December 2014, American Chemical Society (ACS)

    Professor Oliver Reiser, Łukasz Berlicki

  19. Structure-Guided, Single-Point Modifications in the Phosphinic Dipeptide Structure Yield Highly Potent and Selective Inhibitors of Neutral Aminopeptidases

    Article • Journal of Medicinal Chemistry, October 2014, American Chemical Society (ACS)

    Łukasz Berlicki

  20. Crystal structure of Aminopeptidase N in complex with the phosphonic acid analogue of leucine (D-(S)-LeuP)

    Article • June 2014, Protein Data Bank, Rutgers University

    Łukasz Berlicki

  21. A three-component synthesis of aminomethylenebis-H-phosphinates

    Article • Tetrahedron Letters, January 2014, Elsevier

    Łukasz Berlicki

  22. Replacement of Thr 32 and Gln 34 in the C -Terminal Neuropeptide Y Fragment 25–36 by cis -Cyclobutane and cis -Cyclopentane β-Amino Acids Shifts Selectivity toward the Y 4 Receptor

    Article • Journal of Medicinal Chemistry, November 2013, American Chemical Society (ACS)

    Łukasz Berlicki, Professor Oliver Reiser

  23. Toward very potent, non-covalent organophosphonate inhibitors of cathepsin C and related enzymes by 2-amino-1-hydroxy-alkanephosphonates dipeptides

    Article • Biochimie, August 2013, Elsevier

    Łukasz Berlicki

  24. Synthesis and Evaluation of Effective Inhibitors of Plant δ1-Pyrroline-5-carboxylate Reductase

    Article • Journal of Agricultural and Food Chemistry, July 2013, American Chemical Society (ACS)

    giuseppe forlani, Łukasz Berlicki

  25. Erratum to: The crystal structure of Sporosarcina pasteurii urease in a complex with citrate provides new hints for inhibitor design

    Article • JBIC Journal of Biological Inorganic Chemistry, March 2013, Springer Science + Business Media

    Dr Michele Cianci, Łukasz Berlicki, Stefano Benini

  26. The crystal structure of Sporosarcina pasteurii urease in a complex with citrate provides new hints for inhibitor design

    Article • JBIC Journal of Biological Inorganic Chemistry, February 2013, Springer Science + Business Media

    Dr Michele Cianci, Professor Stefano Ciurli, Łukasz Berlicki, Stefano Benini

  27. An integrated approach to the ligand binding specificity of Neisseria meningitidis M1 alanine aminopeptidase by fluorogenic substrate profiling, inhibitory studies and molecular modeling

    Article • Biochimie, February 2013, Elsevier

    Łukasz Berlicki

  28. Phosphorylation as a method of tuning the enantiodiscrimination potency of quinine-An NMR study

    Article • Chirality, February 2012, Wiley

    Łukasz Berlicki

  29. α,β- und α,α,β,β-Peptidfoldamere basierend auf cis-β-Aminocyclopentancarbonsäure

    Article • Angewandte Chemie, January 2012, Wiley

    Professor Oliver Reiser, Łukasz Berlicki

  30. Unique α,β- and α,α,β,β-Peptide Foldamers Based on cis-β-Aminocyclopentanecarboxylic Acid

    Article • Angewandte Chemie International Edition, January 2012, Wiley

    Professor Oliver Reiser, Łukasz Berlicki

  31. Remarkable Potential of the α-Aminophosphonate/Phosphinate Structural Motif in Medicinal Chemistry

    Article • Journal of Medicinal Chemistry, September 2011, American Chemical Society (ACS)

    Łukasz Berlicki

  32. δ1-Pyrroline-5-carboxylate reductase as a new target for therapeutics: inhibition of the enzyme from Streptococcus pyogenes and effects in vivo

    Article • Amino Acids, July 2011, Springer Science + Business Media

    giuseppe forlani, Łukasz Berlicki

  33. N-substituted aminomethanephosphonic and aminomethane-P-methylphosphinic acids as inhibitors of ureases

    Article • Amino Acids, May 2011, Springer Science + Business Media

    Łukasz Berlicki

  34. Urease inhibitors as potential drugs for gastric and urinary tract infections: a patent review

    Article • Expert Opinion on Therapeutic Patents, April 2011, Informa Healthcare

    Łukasz Berlicki

  35. Computer-Aided Optimization of Phosphinic Inhibitors of Bacterial Ureases

    Article • Journal of Medicinal Chemistry, August 2010, American Chemical Society (ACS)

    Łukasz Berlicki

  36. Enantiodifferentiation of α-hydroxyalkanephosphonic acids in31P NMR with application of α-cyclodextrin as chiral discriminating agent

    Article • Chirality, January 2010, Wiley

    Łukasz Berlicki

  37. Cinchona alkaloids as privileged chiral solvating agents for the enantiodiscrimination of N-protected aminoalkanephosphonates—a comparative NMR study

    Article • Tetrahedron Asymmetry, December 2009, Elsevier

    Łukasz Berlicki

  38. Insight into the mechanism of three component condensation leading to aminomethylenebisphosphonates

    Article • Journal of Organometallic Chemistry, November 2009, Elsevier

    Łukasz Berlicki

  39. Effectiveness and mode of action of phosphonate inhibitors of plant glutamine synthetase

    Article • Pest Management Science, August 2009, Wiley

    giuseppe forlani, Łukasz Berlicki

  40. Design, Synthesis, and Evaluation of Novel Organophosphorus Inhibitors of Bacterial Ureases

    Article • Journal of Medicinal Chemistry, September 2008, American Chemical Society (ACS)

    Łukasz Berlicki

  41. Inhibitors of Glutamine Synthetase and their Potential Application in Medicine

    Article • Mini-Reviews in Medicinal Chemistry, August 2008, Bentham Science Publishers

    Łukasz Berlicki

  42. Tailoring the Structure of Aminobisphosphonates To Target Plant P5C Reductase

    Article • Journal of Agricultural and Food Chemistry, April 2008, American Chemical Society (ACS)

    giuseppe forlani, Łukasz Berlicki

  43. Organophosphorus Supramolecular Chemistry. Part 2. Organophosphorus Receptors

    Article • Current Organic Chemistry, December 2007, Bentham Science Publishers

    Łukasz Berlicki

  44. Chiral discrimination of ethyl and phenyl N-benzyloxycarbonylaminophosphonates by cyclodextrins

    Article • Tetrahedron Asymmetry, July 2007, Elsevier

    Łukasz Berlicki

  45. Plant P5C Reductase as a New Target for Aminomethylenebisphosphonates

    Article • Journal of Agricultural and Food Chemistry, May 2007, American Chemical Society (ACS)

    giuseppe forlani, Łukasz Berlicki

  46. Analysis of pD-Dependent complexation ofN-benzyloxycarbonylaminophosphonic acids by α-cyclodextrin. Enantiodifferentiation of phosphonic acid pKa values

    Article • Chirality, January 2007, Wiley

    Łukasz Berlicki

  47. Enantiodifferentiation of N-benzyloxycarbonylaminophosphonic and phosphinic acids and their esters using cyclodextrins by means of capillary electrophoresis

    Article • Journal of Chromatography A, January 2007, Elsevier

    Łukasz Berlicki

  48. Organophosphorus Supramolecular Chemistry Part 1. Receptors for Organophosphorus Compounds

    Article • Current Organic Chemistry, December 2006, Bentham Science Publishers

    Łukasz Berlicki

  49. Computer-aided analysis of the interactions of glutamine synthetase with its inhibitors

    Article • Bioorganic & Medicinal Chemistry, July 2006, Elsevier

    Łukasz Berlicki

  50. Phosphinothricin Analogues as Inhibitors of Plant Glutamine Synthetases

    Article • Journal of Agricultural and Food Chemistry, January 2006, American Chemical Society (ACS)

    giuseppe forlani, Łukasz Berlicki

  51. Computer-Aided Analysis and Design of Phosphonic and Phosphinic Enzyme Inhibitors as Potential Drugs and Agrochemicals

    Article • Current Organic Chemistry, December 2005, Bentham Science Publishers

    Łukasz Berlicki

  52. Design, Synthesis, and Activity of Analogues of Phosphinothricin as Inhibitors of Glutamine Synthetase

    Article • Journal of Medicinal Chemistry, September 2005, American Chemical Society (ACS)

    giuseppe forlani, Łukasz Berlicki

  53. Herbicidal Pyridyl Derivatives of Aminomethylene-bisphosphonic Acid Inhibit Plant Glutamine Synthetase

    Article • Journal of Agricultural and Food Chemistry, May 2004, American Chemical Society (ACS)

    giuseppe forlani, Łukasz Berlicki

  54. Cyclodextrins as NMR probes in the study of the enantiomeric compositions of N-benzyloxycarbonylamino-phosphonic and phosphinic acids

    Article • Tetrahedron Asymmetry, May 2004, Elsevier

    Łukasz Berlicki

  55. Enantiodifferentiation of aminophosphonic and aminophosphinic acids with α- and β-cyclodextrins

    Article • Tetrahedron Asymmetry, June 2003, Elsevier

    Łukasz Berlicki

  56. The use of molecular modelling for comparison of three possible modes of action of herbicidally active derivatives of aminomethylenebisphosphonic acid

    Article • Pesticide Biochemistry and Physiology, June 2002, Elsevier

    Łukasz Berlicki

  57. From Inhibitors of Lap to Inhibitors of Pal

    Article • Springer Science + Business Media

    Łukasz Berlicki