All Stories

  1. Adenosine deaminase acting on RNA 1 and receptor-interacting serine/threonine-protein kinase-1 orchestrate the Z-DNA-binding protein 1–mediated PANoptosis and mouse heart transplant rejection

    Article • Arabian archaeology and epigraphy, February 2026, Elsevier

    Dr. Zhu-Xu Zhang

  2. ADAR1 orchestrates the ZBP1-mediated PANoptosis and heart transplant rejection

    Article • September 2024, openRxiv

    Dr. Zhu-Xu Zhang

  3. An acidic pH environment converts necroptosis to apoptosis

    Article • Biochemical and Biophysical Research Communications, September 2024, Elsevier

    Dr. Zhu-Xu Zhang

  4. The CaMK Family Differentially Promotes Necroptosis and Mouse Cardiac Graft Injury and Rejection

    Article • International Journal of Molecular Sciences, April 2024, MDPI AG

    Dr. Zhu-Xu Zhang

  5. Inhibition of NK cell cytotoxicity by tubular epithelial cell expression of Clr-b and Clr-f

    Article • Current Research in Immunology, January 2024, Elsevier

    Dr. Zhu-Xu Zhang

  6. Nicotinamide mononucleotide as a therapeutic agent to alleviate multi-organ failure in sepsis

    Article • Journal of Translational Medicine, December 2023, Springer Science + Business Media

    Dr. Zhu-Xu Zhang

  7. MLKL-mediated necroptosis is a target for cardiac protection in mouse models of type-1 diabetes

    Article • Cardiovascular Diabetology, August 2022, Springer Science + Business Media

    Dr. Zhu-Xu Zhang

  8. Cyclophilin D Regulates the Nuclear Translocation of AIF, Cardiac Endothelial Cell Necroptosis and Murine Cardiac Transplant Injury

    Article • International Journal of Molecular Sciences, October 2021, MDPI AG

    Dr. Zhu-Xu Zhang

  9. Toll-like receptor 3 is an endogenous sensor of cell death and a potential target for induction of long-term cardiac transplant survival

    Article • Arabian archaeology and epigraphy, October 2021, Elsevier

    Dr. Zhu-Xu Zhang

  10. miR-149-3p reverses CD8 + T-cell exhaustion by reducing inhibitory receptors and promoting cytokine secretion in breast cancer cells

    Article • Open Biology, October 2019, Royal Society Publishing

    Dr. Zhu-Xu Zhang

  11. Loss of receptor interacting protein kinases 3 and caspase‐8 augments intrinsic apoptosis in tubular epithelial cell and promote kidney ischaemia‐reperfusion injury

    Article • Nephrology, April 2019, Wiley

    Dr. Zhu-Xu Zhang

  12. Increased calpain-1 in mitochondria induces dilated heart failure in mice: role of mitochondrial superoxide anion

    Article • Basic Research in Cardiology, March 2019, Springer Science + Business Media

    Dr. Zhu-Xu Zhang

  13. Mitochondrial permeability regulates cardiac endothelial cell necroptosis and cardiac allograft rejection

    Article • Arabian archaeology and epigraphy, October 2018, Wiley

    Dr. Zhu-Xu Zhang

  14. Targeted-gene silencing of BRAF to interrupt BRAF/MEK/ERK pathway synergized photothermal therapeutics for melanoma using a novel FA-GNR-siBRAF nanosystem

    Article • Nanomedicine Nanotechnology Biology and Medicine, July 2018, Elsevier

    Dr. Zhu-Xu Zhang

  15. T cell mediates necrototic cell death

    Article • Transplantation, September 2017, Wolters Kluwer Health

    Dr. Zhu-Xu Zhang

  16. pH regulate cell death

    Article • Journal of Immunology Research, January 2017, Hindawi Publishing Corporation

    Dr. Zhu-Xu Zhang

  17. Prevention of allograft rejection in heart transplantation through concurrent gene silencing of TLR and Kinase signaling pathways

    Article • Scientific Reports, September 2016, Nature

    Dr. Zhu-Xu Zhang

  18. Regulatory non-coding RNA: new instruments in the orchestration of cell death

    Article • Cell Death and Disease, August 2016, Nature

    Dr. Zhu-Xu Zhang

  19. Natural Killer Cells Mediate Long-term Kidney Allograft Injury

    Article • Transplantation, May 2015, Wolters Kluwer Health

    Dr. Zhu-Xu Zhang

  20. IL-37 inhibits IL-18-induced tubular epithelial cell expression of pro-inflammatory cytokines and renal ischemia-reperfusion injury

    Article • Kidney International, February 2015, Elsevier

    Dr. Zhu-Xu Zhang

  21. Natural Killer Cells Play a Critical Role in Cardiac Allograft Vasculopathy in an Interleukin-6–Dependent Manner

    Article • Transplantation, November 2014, Wolters Kluwer Health

    Dr. Zhu-Xu Zhang

  22. Necroptosis Regulates Cardiac Allograft Survival

    Article • Arabian archaeology and epigraphy, August 2014, Elsevier

    Dr. Zhu-Xu Zhang

  23. Serine Protease Inhibitor-6 Inhibits Granzyme B–Mediated Injury of Renal Tubular Cells and Promotes Renal Allograft Survival

    Article • Transplantation, August 2014, Wolters Kluwer Health

    Dr. Zhu-Xu Zhang

  24. RIPK3-Mediated Necroptosis Regulates Cardiac Allograft Rejection.

    Article • Transplantation, July 2014, Wolters Kluwer Health

    Dr. Zhu-Xu Zhang

  25. NK Cells Mediate Chronic Kidney Allograft Injury.

    Article • Transplantation, July 2014, Wolters Kluwer Health

    Dr. Zhu-Xu Zhang

  26. DN Treg Cells Specifically Suppress Cognate Alloreactive Memory T Cell By Granzyme B, and Prolong Allograft Survival.

    Article • Transplantation, July 2014, Wolters Kluwer Health

    Dr. Zhu-Xu Zhang

  27. IL-37 Inhibits IL-18-Induced Tubular Epithelial Cell Expression of Pro-Inflammatory Cytokines and Renal Ischemia-Reperfusion Injury.

    Article • Transplantation, July 2014, Wolters Kluwer Health

    Dr. Zhu-Xu Zhang

  28. Synergic silencing of costimulatory molecules prevents cardiac allograft rejection

    Article • Journal of Translational Medicine, May 2014, Springer Science + Business Media

    Dr. Zhu-Xu Zhang

  29. Spi6 Protects Alloreactive CD4+ But Not CD8+ Memory T Cell From Granzyme B Attack by Double-Negative T Regulatory Cell

    Article • Arabian archaeology and epigraphy, March 2014, Elsevier

    Dr. Zhu-Xu Zhang

  30. Glycyrrhizic Acid Ameliorates HMGB1-Mediated Cell Death and Inflammation after Renal Ischemia Reperfusion Injury

    Article • American Journal of Nephrology, January 2014, Karger Publishers

    Dr. Zhu-Xu Zhang

  31. RIPK3-Mediated Necroptosis Promotes Donor Kidney Inflammatory Injury and Reduces Allograft Survival

    Article • Arabian archaeology and epigraphy, November 2013, Elsevier

    Dr. Zhu-Xu Zhang

  32. Double negative Treg cells promote nonmyeloablative bone marrow chimerism by inducing T-cell clonal deletion and suppressing NK cell function

    Article • European Journal of Immunology, April 2012, Wiley

    Dr. Zhu-Xu Zhang

  33. Use of RNA interference to minimize ischemia reperfusion injury

    Article • Transplantation Reviews, April 2012, Elsevier

    Dr. Zhu-Xu Zhang

  34. NK cells mediate chronic kidney allograft injury (169.26)

    Article • The Journal of Immunology, April 2011, Oxford University Press (OUP)

    Dr. Zhu-Xu Zhang

  35. Adoptive transfer of DNT cells induces long-term cardiac allograft survival and augments recipient CD4+Foxp3+ Treg cell accumulation

    Article • Transplant Immunology, January 2011, Elsevier

    Dr. Zhu-Xu Zhang

  36. Anti-IL-2 receptor antibody decreases cytokine-induced apoptosis of human renal tubular epithelial cells (TEC)

    Article • Nephrology Dialysis Transplantation, December 2010, Oxford University Press (OUP)

    Dr. Zhu-Xu Zhang

  37. Osteopontin Expressed in Tubular Epithelial Cells Regulates NK Cell-Mediated Kidney Ischemia Reperfusion Injury

    Article • The Journal of Immunology, July 2010, Oxford University Press (OUP)

    Dr. Zhu-Xu Zhang

  38. HYPOXIA INDUCED TUBULAR CELL (TEC) RELEASE OF HMGB1 PROPAGATES RENAL INJURY BY EFFECTS ON TEC VIABILITY AND NK CELL ACTIVATION

    Article • Transplantation, July 2010, Wolters Kluwer Health

    Dr. Zhu-Xu Zhang

  39. NK CELLS MEDIATE CHRONIC KIDNEY ALLOGRAFT INJURY IN TOLERANT PARENT TO F1 TRANSPLANTS

    Article • Transplantation, July 2010, Wolters Kluwer Health

    Dr. Zhu-Xu Zhang

  40. A novel allergen-specific therapy for allergy using CD40-silenced dendritic cells

    Article • Journal of Allergy and Clinical Immunology, March 2010, Elsevier

    Dr. Zhu-Xu Zhang

  41. Preventing Tissue Injury Using siRNA

    Article • January 2010, Springer Science + Business Media

    Dr. Zhu-Xu Zhang

  42. Small Interfering RNA Targeting RelB Protects Against Renal Ischemia-reperfusion Injury

    Article • Transplantation, May 2009, Wolters Kluwer Health

    Dr. Zhu-Xu Zhang

  43. A novel in vivo siRNA delivery system specifically targeting dendritic cells and silencing CD40 genes for immunomodulation

    Article • Blood, March 2009, American Society of Hematology

    Dr. Zhu-Xu Zhang

  44. NK Cells Induce Apoptosis in Tubular Epithelial Cells and Contribute to Renal Ischemia-Reperfusion Injury

    Article • The Journal of Immunology, December 2008, Oxford University Press (OUP)

    Dr. Zhu-Xu Zhang

  45. Generation of therapeutic dendritic cells and regulatory T cells for preventing allogeneic cardiac graft rejection

    Article • Clinical Immunology, June 2008, Elsevier

    Dr. Zhu-Xu Zhang

  46. Adoptive transfer of double negative T regulatory cells induces B-cell death in vivo and alters rejection pattern of rat-to-mouse heart transplantation

    Article • Xenotransplantation, February 2008, Wiley

    Dr. Zhu-Xu Zhang

  47. Tolerogenic dendritic cells transferring hyporesponsiveness and synergizing T regulatory cells in transplant tolerance

    Article • International Immunology, January 2008, Oxford University Press (OUP)

    Dr. Zhu-Xu Zhang

  48. Donor double-negative Treg promote allogeneic mixed chimerism and tolerance

    Article • European Journal of Immunology, December 2007, Wiley

    Dr. Zhu-Xu Zhang

  49. Immune Modulation and Tolerance Induction by RelB-Silenced Dendritic Cells through RNA Interference

    Article • The Journal of Immunology, May 2007, Oxford University Press (OUP)

    Dr. Zhu-Xu Zhang

  50. Double-Negative T Cells, Activated by Xenoantigen, Lyse Autologous B and T Cells Using a Perforin/Granzyme-Dependent, Fas-Fas Ligand-Independent Pathway

    Article • The Journal of Immunology, November 2006, Oxford University Press (OUP)

    Dr. Zhu-Xu Zhang

  51. Double-Negative T Regulatory Cells Can Develop Outside the Thymus and Do Not Mature from CD8+ T Cell Precursors

    Article • The Journal of Immunology, September 2006, Oxford University Press (OUP)

    Dr. Zhu-Xu Zhang

  52. Expression Profiling of Murine Double-Negative Regulatory T Cells Suggest Mechanisms for Prolonged Cardiac Allograft Survival

    Article • The Journal of Immunology, April 2005, Oxford University Press (OUP)

    Dr. Zhu-Xu Zhang

  53. IL-10 Induces Regulatory T Cell Apoptosis by Up-Regulation of the Membrane Form of TNF-α

    Article • The Journal of Immunology, January 2004, Oxford University Press (OUP)

    Dr. Zhu-Xu Zhang

  54. The Immune Regulatory Function of Lymphoproliferative Double Negative T Cells In Vitro and In Vivo

    Article • Journal of Experimental Medicine, July 2002, Rockefeller University Press

    Dr. Zhu-Xu Zhang

  55. Ly-6A is critical for the function of double negative regulatory T cells

    Article • European Journal of Immunology, June 2002, Wiley

    Dr. Zhu-Xu Zhang

  56. Interaction of the E1A Oncoprotein with Yak1p, a Novel Regulator of Yeast Pseudohyphal Differentiation, and Related Mammalian Kinases

    Article • Molecular Biology of the Cell, March 2001, American Society for Cell Biology (ASCB)

    Dr. Zhu-Xu Zhang

  57. Suppression of alloimmune responses in vitro and in vivo by CD3+CD8−CD4−αβ+ regulatory T cells

    Article • Transplantation Proceedings, February 2001, Elsevier

    Dr. Zhu-Xu Zhang

  58. Identification of a previously unknown antigen-specific regulatory T cell and its mechanism of suppression

    Article • Nature Medicine, July 2000, Springer Science + Business Media

    Dr. Zhu-Xu Zhang

  59. Characterization of a Monoclonal Antibody and Its Single-Chain Antibody Fragment Recognizing the Nucleoside Triphosphatase/Helicase Domain of the Hepatitis C Virus Nonstructural 3 Protein

    Article • Clinical and Diagnostic Laboratory Immunology, January 2000, ASM Journals

    Associate Professor Margaret Chen, Dr. Zhu-Xu Zhang

  60. Immune responses to the hepatitis C virus NS4A protein are profoundly influenced by the combination of the viral genotype and the host major histocompatibility complex.

    Article • Journal of General Virology, November 1997, Society for General Microbiology

    Dr. Zhu-Xu Zhang

  61. Immunogenicity and antigenicity of the ATPase/helicase domain of the hepatitis C virus non-structural 3 protein

    Article • Journal of General Virology, November 1996, Society for General Microbiology

    Associate Professor Margaret Chen, Dr. Zhu-Xu Zhang

  62. Passive adsorption of immunologically active and inactive synthetic peptides to polystyrene is influenced by the proportion of non-polar residues in the peptide

    Article • Immunology Letters, May 1995, Elsevier

    Dr. Zhu-Xu Zhang