All Stories

  1. Extracorporeal Respiratory Support With a Miniature Integrated Pediatric Pump-Lung Device in an Acute Ovine Respiratory Failure Model

    Article • Artificial Organs, April 2016, Wiley

    Professor Zhongjun J Wu

  2. Paradoxical Effect of Nonphysiological Shear Stress on Platelets and von Willebrand Factor

    Article • Artificial Organs, November 2015, Wiley

    Professor Zhongjun J Wu

  3. Effects of small platform catheter-based left ventricular assist device support on regional myocardial signal transduction

    Article • Journal of Thoracic and Cardiovascular Surgery, November 2015, Elsevier

    Professor Zhongjun J Wu

  4. Systemic Inflammatory Response Syndrome in End-Stage Heart Failure Patients Following Continuous-Flow Left Ventricular Assist Device Implantation: Differences in Plasma Redox Status and Leukocyte Activation

    Article • Artificial Organs, September 2015, Wiley

    Professor Zhongjun J Wu

  5. Oxidative Stress Induced Modulation of Platelet Integrin αIIbβ3 Expression and Shedding During Major Bleeding in Heart Failure Patients Supported By Continuous Flow Left Ventricular Assist Devices

    Article • Journal of Cardiac Failure, August 2015, Elsevier

    Professor Zhongjun J Wu

  6. Activation and shedding of platelet glycoprotein IIb/IIIa under non-physiological shear stress

    Article • Molecular and Cellular Biochemistry, July 2015, Springer Science + Business Media

    Professor Zhongjun J Wu

  7. Systemic Inflammatory Response Syndrome After Contentious-Flow Left Ventricular Assist Device Implantation and Change in Platelet Mitochondrial Membrane Potential

    Article • Journal of Cardiac Failure, July 2015, Elsevier

    Professor Zhongjun J Wu

  8. Effects of Cardiopulmonary Support With a Novel Pediatric Pump-Lung in a 30-Day Ovine Animal Model

    Article • Artificial Organs, April 2015, Wiley

    Professor Zhongjun J Wu

  9. Shear-Induced Hemolysis: Species Differences

    Article • Artificial Organs, April 2015, Wiley

    Professor Zhongjun J Wu

  10. Shear-induced platelet receptor shedding by non-physiological high shear stress with short exposure time: Glycoprotein Ibα and glycoprotein VI

    Article • Thrombosis Research, April 2015, Elsevier

    Professor Zhongjun J Wu

  11. Quantification of Shear-Induced Platelet Activation: High Shear Stresses for Short Exposure Time

    Article • Artificial Organs, March 2015, Wiley

    Professor Zhongjun J Wu

  12. Comparison of Intraplatelet Reactive Oxygen Species, Mitochondrial Damage, and Platelet Apoptosis After Implantation of Three Continuous Flow Left Ventricular Assist Devices

    Article • ASAIO Journal, January 2015, Wolters Kluwer Health

    Professor Zhongjun J Wu

  13. Mechanical Circulatory Support of a Univentricular Fontan Circulation with a Continuous Axial-Flow Pump in a Piglet Model

    Article • ASAIO Journal, January 2015, Wolters Kluwer Health

    Professor Zhongjun J Wu

  14. Intraplatelet reactive oxygen species, mitochondrial damage and platelet apoptosis augment non-surgical bleeding in heart failure patients supported by continuous-flow left ventricular assist device

    Article • Platelets, August 2014, Taylor & Francis

    Professor Zhongjun J Wu

  15. Right ventricular unloading and respiratory support with a wearable artificial pump-lung in an ovine model

    Article • The Journal of Heart and Lung Transplantation, August 2014, Elsevier

    Professor Zhongjun J Wu

  16. Systemic Inflammatory Response Syndrome after Contentious-Flow Left Ventricular Assist Device Implantation: Change in Platelet Mitochondrial Membrane Potential

    Article • Journal of Cardiac Failure, August 2014, Elsevier

    Professor Zhongjun J Wu

  17. Blood-aggregating hydrogel particles for use as a hemostatic agent

    Article • Acta Biomaterialia, February 2014, Elsevier

    Professor Zhongjun J Wu

  18. Pim-1 Kinase Cooperates with Serum Signals Supporting Mesenchymal Stem Cell Propagation

    Article • Cells Tissues Organs, January 2014, Karger Publishers

    Professor Zhongjun J Wu

  19. Multiscale Characterization of Impact of Infarct Size on Myocardial Remodeling in an Ovine Infarct Model

    Article • Cells Tissues Organs, January 2014, Karger Publishers

    Professor Zhongjun J Wu

  20. Platelet glycoprotein Ibα ectodomain shedding and non-surgical bleeding in heart failure patients supported by continuous-flow left ventricular assist devices

    Article • The Journal of Heart and Lung Transplantation, January 2014, Elsevier

    Professor Zhongjun J Wu

  21. Computational Study of the Blood Flow in Three Types of 3D Hollow Fiber Membrane Bundles

    Article • Journal of Biomechanical Engineering, November 2013, ASME International

    Professor Zhongjun J Wu

  22. Prophylactic amiodarone and lidocaine improve survival in an ovine model of large size myocardial infarction

    Article • Journal of Surgical Research, November 2013, Elsevier

    Professor Zhongjun J Wu

  23. Pim-1 mediated signaling during the process of cardiac remodeling following myocardial infarction in ovine hearts

    Article • Journal of Molecular and Cellular Cardiology, October 2013, Elsevier

    Professor Zhongjun J Wu

  24. In vitroandin vivoevaluation of polymer hydrogels for hemorrhage control

    Article • Journal of Biomaterials Science Polymer Edition, October 2013, Taylor & Francis

    Professor Zhongjun J Wu

  25. Developing a novel large animal model of trauma-induced systemic inflammatory response syndrome

    Article • Journal of the American College of Surgeons, September 2013, Elsevier

    Professor Zhongjun J Wu

  26. Regional imbalanced activation of the calcineurin/BAD apoptotic pathway and the PI3K/Akt survival pathway after myocardial infarction

    Article • International Journal of Cardiology, June 2013, Elsevier

    Professor Zhongjun J Wu

  27. Short-Term Mechanical Unloading With Left Ventricular Assist Devices After Acute Myocardial Infarction Conserves Calcium Cycling and Improves Heart Function

    Article • JACC Cardiovascular Interventions, April 2013, Elsevier

    Professor Zhongjun J Wu

  28. Biocompatibility Assessment of a Long-Term Wearable Artificial Pump-Lung in Sheep

    Article • Artificial Organs, March 2013, Wiley

    Professor Zhongjun J Wu

  29. Ex Vivo Lung Evaluation of Prearrest Heparinization in Donation After Cardiac Death

    Article • Annals of Surgery, March 2013, Wolters Kluwer Health

    Professor Zhongjun J Wu

  30. Comparison and Experimental Validation of Fluid Dynamic Numerical Models for a Clinical Ventricular Assist Device

    Article • Artificial Organs, February 2013, Wiley

    Professor Zhongjun J Wu

  31. Pre-clinical evaluation of the infant Jarvik 2000 heart in a neonate piglet model

    Article • The Journal of Heart and Lung Transplantation, January 2013, Elsevier

    Professor Zhongjun J Wu

  32. Initial Experience with a Juvenile Sheep Model for Evaluation of the Pediatric Intracorporeal Ventricular Assist Services

    Article • ASAIO Journal, January 2013, Wolters Kluwer Health

    Professor Zhongjun J Wu

  33. Oxidative Stress, DNA Damage and Repair in Heart Failure Patients after Implantation of Continuous Flow Left Ventricular Assist Devices

    Article • International Journal of Medical Sciences, January 2013, Ivyspring International Publisher

    Professor Zhongjun J Wu

  34. Experimental Validation of Fluid Dynamic Numerical Models in Blood Pump Simulation

    Article • June 2012, ASME International

    Professor Zhongjun J Wu

  35. Evaluation of Eulerian and Lagrangian Models for Hemolysis Estimation

    Article • ASAIO Journal, January 2012, Wolters Kluwer Health

    Professor Zhongjun J Wu

  36. Advanced Surface Modifications for Blood-Contacting Surfaces of Medical Devices

    Article • International Journal of Biomaterials, January 2012, Hindawi Publishing Corporation

    Professor Zhongjun J Wu

  37. Design Optimization of a Wearable Artificial Pump-Lung Device With Computational Modeling

    Article • Journal of Medical Devices, January 2012, ASME International

    Professor Zhongjun J Wu

  38. A Quantitative Comparison of Mechanical Blood Damage Parameters in Rotary Ventricular Assist Devices: Shear Stress, Exposure Time and Hemolysis Index

    Article • Journal of Biomechanical Engineering, January 2012, ASME International

    Professor Zhongjun J Wu

  39. A novel wearable pump-lung device: In vitro and acute in vivo study

    Article • The Journal of Heart and Lung Transplantation, January 2012, Elsevier

    Professor Zhongjun J Wu

  40. Thirty-Day In-Vivo Performance of a Wearable Artificial Pump-Lung for Ambulatory Respiratory Support

    Article • The Annals of Thoracic Surgery, January 2012, Elsevier

    Professor Zhongjun J Wu

  41. Computational Model-Based Design of a Wearable Artificial Pump-Lung for Cardiopulmonary/Respiratory Support

    Article • Artificial Organs, December 2011, Wiley

    Professor Zhongjun J Wu

  42. Computational Fluid Dynamics and Experimental Characterization of the Pediatric Pump-Lung

    Article • Cardiovascular Engineering and Technology, November 2011, Springer Science + Business Media

    Professor Zhongjun J Wu

  43. Ambulatory veno-venous extracorporeal membrane oxygenation: Innovation and pitfalls

    Article • Journal of Thoracic and Cardiovascular Surgery, October 2011, Elsevier

    Professor Zhongjun J Wu

  44. Study of Flow-Induced Hemolysis Using Novel Couette-Type Blood-Shearing Devices

    Article • Artificial Organs, August 2011, Wiley

    Professor Zhongjun J Wu

  45. Analysis of Infarct Size on Myocardial Infarction Remodeling

    Article • June 2011, ASME International

    Professor Zhongjun J Wu

  46. Differences in Shear Stress, Residence Time and Estimates of Hemolysis Between Different Ventricular Assist Devices

    Article • June 2011, ASME International

    Professor Zhongjun J Wu

  47. The use of computational fluid dynamics in the development of ventricular assist devices

    Article • Medical Engineering & Physics, April 2011, Elsevier

    Professor Zhongjun J Wu

  48. FVII Dependent Coagulation Activation in Citrated Plasma by Polymer Hydrogels

    Article • Biomacromolecules, December 2010, American Chemical Society (ACS)

    Professor Zhongjun J Wu

  49. Computational Characterization of Flow and Hemolytic Performance of the UltraMag Blood Pump for Circulatory Support

    Article • Artificial Organs, December 2010, Wiley

    Professor Zhongjun J Wu

  50. Micro-scale modeling of flow and oxygen transfer in hollow-fiber membrane bundle

    Article • Journal of Membrane Science, October 2010, Elsevier

    Professor Zhongjun J Wu

  51. Design Optimization of a Wearable Artificial Pump-Lung Device With Computational Modeling

    Article • June 2010, ASME International

    Professor Zhongjun J Wu

  52. Early Remodeling Strain Levels Can Predict the Progression of Remodeling of the Left Ventricle Post Myocardial Infarction

    Article • June 2010, ASME International

    Professor Zhongjun J Wu

  53. The Effect of Impeller Position on CFD Calculations of Blood Flow in Magnetically Levitated Centrifugal Blood Pumps

    Article • June 2010, ASME International

    Professor Zhongjun J Wu

  54. Computational Fluid Dynamics Analysis of Thrombosis Potential in Left Ventricular Assist Device Drainage Cannulae

    Article • ASAIO Journal, May 2010, Wolters Kluwer Health

    Professor Zhongjun J Wu

  55. In Vivo Experience of the Child-Size Pediatric Jarvik 2000 Heart: Update

    Article • ASAIO Journal, May 2010, Wolters Kluwer Health

    Professor Zhongjun J Wu

  56. Computational Design and In Vitro Characterization of an Integrated Maglev Pump-Oxygenator

    Article • Artificial Organs, October 2009, Wiley

    Professor Zhongjun J Wu

  57. Bioengineering Quantification of Left Ventricular Remodeling Following Myocardial Infarction

    Article • June 2009, ASME International

    Professor Zhongjun J Wu

  58. Computational Analysis of a Wearable Artificial Pump Lung Device in Terms of Rotor/Stator Interactions

    Article • June 2009, ASME International

    Professor Zhongjun J Wu

  59. Functional and Biocompatibility Performances of an Integrated Maglev Pump-Oxygenator

    Article • Artificial Organs, January 2009, Wiley

    Professor Zhongjun J Wu

  60. Strain Mapping of LV Myocardium and its Correlation With Activation of Apoptotic Molecular Pathways Post Infarction

    Article • June 2008, ASME International

    Professor Zhongjun J Wu

  61. 3D Flow Modeling and Blood Damage Characterization of the UltraMag™ Blood Pump

    Article • June 2008, ASME International

    Professor Zhongjun J Wu

  62. Regional remodeling strain and its association with myocardial apoptosis after myocardial infarction in an ovine model

    Article • Journal of Thoracic and Cardiovascular Surgery, May 2008, Elsevier

    Professor Zhongjun J Wu

  63. CFD Assisted Design of a Wearable Artificial Pump Lung Device

    Article • January 2008, ASME International

    Professor Zhongjun J Wu

  64. Strain related changes in regional myocardial cyclin-dependent kinase (Cdk) inhibitor protein, p21 post-myocardial infarction in ovine model

    Article • Journal of the American College of Surgeons, September 2007, Elsevier

    Professor Zhongjun J Wu

  65. Early In Vivo Experience With the Pediatric Jarvik 2000 Heart

    Article • ASAIO Journal, May 2007, Wolters Kluwer Health

    Professor Zhongjun J Wu

  66. Characterization of membrane blood oxygenation devices using computational fluid dynamics

    Article • Journal of Membrane Science, February 2007, Elsevier

    Professor Zhongjun J Wu

  67. Optimization of a Miniature Maglev Ventricular Assist Device for Pediatric Circulatory Support

    Article • ASAIO Journal, January 2007, Wolters Kluwer Health

    Professor Zhongjun J Wu

  68. Strain-related regional alterations of calcium-handling proteins in myocardial remodeling

    Article • Journal of Thoracic and Cardiovascular Surgery, October 2006, Elsevier

    Professor Zhongjun J Wu

  69. Regional systolic and remodeling strain differences during cardiac remodeling

    Article • Journal of the American College of Surgeons, September 2006, Elsevier

    Professor Zhongjun J Wu

  70. ESTIMATION OF FLOW-INDUCED BLOOD DAMAGE IN BIOMEDICAL DEVICES

    Article • ASAIO Journal, March 2006, Wolters Kluwer Health

    Professor Zhongjun J Wu

  71. COMPENSATORY HEMODYNAMIC AND BIOLOGIC RESPONSES TO PEDIATRIC CIRCULATORY SUPPORT IN LAMBS

    Article • ASAIO Journal, March 2006, Wolters Kluwer Health

    Professor Zhongjun J Wu

  72. CHRONIC IN-VIVO HEMODYNAMIC STUDY OF THE PEDIATRIC JARVIK 2000 HEART

    Article • ASAIO Journal, March 2006, Wolters Kluwer Health

    Professor Zhongjun J Wu

  73. Computational and Experimental Evaluation of the Fluid Dynamics and Hemocompatibility of the CentriMag Blood Pump

    Article • Artificial Organs, March 2006, Wiley

    Professor Zhongjun J Wu

  74. Progress toward an ambulatory pump-lung

    Article • Journal of Thoracic and Cardiovascular Surgery, October 2005, Elsevier

    Professor Zhongjun J Wu

  75. MYOCARDIAL STRAIN MAP OF REMODELING

    Article • ASAIO Journal, March 2005, Wolters Kluwer Health

    Professor Zhongjun J Wu

  76. REGIONAL SERCA2a PROTEIN EXPRESSION IN THE POST-MI MODEL OF HEART FAILURE

    Article • ASAIO Journal, March 2005, Wolters Kluwer Health

    Professor Zhongjun J Wu

  77. Effects of Left Ventricular Assist Device Support and Outflow Graft Location Upon Aortic Blood Flow

    Article • ASAIO Journal, September 2004, Wolters Kluwer Health

    Professor Zhongjun J Wu

  78. Design and Hydrodynamic Evaluation of a Novel Pulsatile Bioreactor for Biologically Active Heart Valves

    Article • Annals of Biomedical Engineering, August 2004, Springer Science + Business Media

    Professor Zhongjun J Wu

  79. EFFECT OF DRAG REDUCING POLYMERS (DRPs) ON RED BLOOD CELL (RBC) FILTERABILITY

    Article • ASAIO Journal, March 2003, Wolters Kluwer Health

    Professor Zhongjun J Wu

  80. Ventricular Assist Devices: Current Status and Future Perspective

    Article • January 2003, Springer Science + Business Media

    Professor Zhongjun J Wu

  81. Effects of Continuous Flow Left Ventricular Assist Device Support on Skin Tissue Microcirculation and Aortic Hemodynamics

    Article • ASAIO Journal, January 2003, Wolters Kluwer Health

    Professor Zhongjun J Wu

  82. Smooth muscle cell hypertrophy of renal cortex arteries with chronic continuous flow left ventricular assist

    Article • The Annals of Thoracic Surgery, January 2003, Elsevier

    Professor Zhongjun J Wu

  83. ALTERED AORTIC HEMODYNAMICS WITH CONTINUOUS FLOW VAD SUPPORT

    Article • ASAIO Journal, March 2002, Wolters Kluwer Health

    Professor Zhongjun J Wu

  84. VISUALIZATION OF WALL SHEAR STRESS IN BLOOD-WETTED ARTIFICIAL ORGANS USING NEW PHOTOCHROMIC LIQUID CRYSTAL SENSOR

    Article • ASAIO Journal, March 2001, Wolters Kluwer Health

    Professor Zhongjun J Wu

  85. Fluid Dynamic Characterization of Operating Conditions for Continuous Flow Blood Pumps

    Article • ASAIO Journal, September 1999, Wolters Kluwer Health

    Professor Zhongjun J Wu

  86. Induction of Ventricular Collapse by an Axial Flow Blood Pump

    Article • ASAIO Journal, September 1998, Wolters Kluwer Health

    Professor Zhongjun J Wu

  87. Novel Ventricular Apical Cannula: In Vitro Evaluation Using Transparent, Compliant Ventricular Casts

    Article • ASAIO Journal, September 1998, Wolters Kluwer Health

    Professor Zhongjun J Wu

  88. Progress on Development of the Nimbus–University of Pittsburgh Axial Flow Left Ventricular Assist System

    Article • ASAIO Journal, September 1998, Wolters Kluwer Health

    Professor Zhongjun J Wu

  89. Continued Development of the Nimbus/University of Pittsburgh (UOP) Axial Flow Left Ventricular Assist System

    Article • ASAIO Journal, September 1997, Wolters Kluwer Health

    Professor Zhongjun J Wu

  90. Ventricular Pressure Slope and Bileaflet Mechanical Heart Valve Closure

    Article • ASAIO Journal, July 1995, Wolters Kluwer Health

    Professor Zhongjun J Wu