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  1. Adipogenic transdifferentiation reprograms EMT-high PDAC cells into a post-mitotic adipocyte-like state and limits metastasis

    Article • Cell Death and Disease, March 2026, Springer Science + Business Media

    Zhi-Gang Zhang

  2. Fibroblastic reticular cell–derived HGF orchestrates sympathetic nerves in tumor-induced lymph node remodeling and metastasis

    Article • May 2025, Springer Science + Business Media

    Zhi-Gang Zhang

  3. Phosphorylation of FOXK2 at Thr13 and Ser30 by PDK2 sustains glycolysis through a positive feedback manner in ovarian cancer

    Article • Oncogene, May 2024, Springer Science + Business Media

    Zhi-Gang Zhang

  4. Adaptive activation of EFNB2/EPHB4 axis promotes post-metastatic growth of colorectal cancer liver metastases by LDLR-mediated cholesterol uptake

    Article • Oncogene, November 2022, Springer Science + Business Media

    Zhi-Gang Zhang

  5. Modeling of cancer-related body-wide effects identifies LTB4 as a diagnostic biomarker for pancreatic cancer

    Article • EBioMedicine, June 2022, Elsevier

    Zhi-Gang Zhang

  6. Spatiotemporal Quantification of Metastatic Tumour Cell Growth and Distribution in Lymph Nodes by Whole-Mount Tissue 3D Imaging

    Article • December 2021, Springer Science + Business Media

    Zhi-Gang Zhang

  7. Reciprocal regulation of LOXL2 and HIF1α drives the Warburg effect to support pancreatic cancer aggressiveness

    Article • Cell Death and Disease, November 2021, Springer Science + Business Media

    Zhi-Gang Zhang

  8. The physiology, pathology and potential therapeutic application of serotonylation

    Article • Journal of Cell Science, June 2021, The Company of Biologists

    Zhi-Gang Zhang

  9. STK3 Suppresses Ovarian Cancer Progression by Activating NF-κB Signaling to Recruit CD8+ T-Cells

    Article • Journal of Immunology Research, September 2020, Hindawi Publishing Corporation

    Zhi-Gang Zhang

  10. MPC1 Deficiency Promotes CRC Liver Metastasis via Facilitating Nuclear Translocation of β-Catenin

    Article • Journal of Immunology Research, August 2020, Hindawi Publishing Corporation

    Zhi-Gang Zhang

  11. Inhibiting Importin 4-mediated nuclear import of CEBPD enhances chemosensitivity by repression of PRKDC-driven DNA damage repair in cervical cancer

    Article • Oncogene, July 2020, Springer Science + Business Media

    Zhi-Gang Zhang

  12. Signalling entrains the peripheral circadian clock

    Article • Cellular Signalling, May 2020, Elsevier

    Zhi-Gang Zhang

  13. Activation of BK Channels Prevents Hepatic Stellate Cell Activation and Liver Fibrosis Through the Suppression of TGFβ1/SMAD3 and JAK/STAT3 Profibrotic Signaling Pathways

    Article • Frontiers in Pharmacology, March 2020, Frontiers

    Zhi-Gang Zhang

  14. Perineural invasion reprograms the immune microenvironment through cholinergic signaling in pancreatic ductal adenocarcinoma

    Article • Cancer Research, February 2020, American Association for Cancer Research (AACR)

    Zhi-Gang Zhang

  15. BCAT2-mediated BCAA catabolism is critical for development of pancreatic ductal adenocarcinoma

    Article • Nature Cell Biology, February 2020, Springer Science + Business Media

    Zhi-Gang Zhang

  16. Transcription factor NFAT5 contributes to the glycolytic phenotype rewiring and pancreatic cancer progression via transcription of PGK1

    Article • Cell Death and Disease, December 2019, Springer Science + Business Media

    Zhi-Gang Zhang

  17. Lysyl oxidase promotes liver metastasis of gastric cancer via facilitating the reciprocal interactions between tumor cells and cancer associated fibroblasts

    Article • EBioMedicine, November 2019, Elsevier

    Zhi-Gang Zhang

  18. The Diverse Function of PD-1/PD-L Pathway Beyond Cancer

    Article • Frontiers in Immunology, October 2019, Frontiers

    Zhi-Gang Zhang

  19. Neurotransmitters: emerging targets in cancer

    Article • Oncogene, September 2019, Springer Science + Business Media

    Zhi-Gang Zhang

  20. Loss of Setd2 promotes Kras-induced acinar-to-ductal metaplasia and epithelia–mesenchymal transition during pancreatic carcinogenesis

    Article • Gut, July 2019, BMJ

    Zhi-Gang Zhang

  21. GPAA1 promotes gastric cancer progression via upregulation of GPI-anchored protein and enhancement of ERBB signalling pathway

    Article • Journal of Experimental & Clinical Cancer Research, May 2019, Springer Science + Business Media

    Zhi-Gang Zhang

  22. Targeting the tumor microenvironment for pancreatic ductal adenocarcinoma therapy

    Article • Chinese Clinical Oncology, April 2019, AME Publishing Company

    Zhi-Gang Zhang

  23. GABRP regulates chemokine signalling, macrophage recruitment and tumour progression in pancreatic cancer through tuning KCNN4-mediated Ca2+ signalling in a GABA-independent manner

    Article • Gut, March 2019, BMJ

    Zhi-Gang Zhang

  24. NPTX2 promotes colorectal cancer growth and liver metastasis by the activation of the canonical Wnt/β-catenin pathway via FZD6

    Article • Cell Death and Disease, March 2019, Springer Science + Business Media

    Zhi-Gang Zhang

  25. Autocrine CTHRC1 activates hepatic stellate cells and promotes liver fibrosis by activating TGF-β signaling

    Article • EBioMedicine, February 2019, Elsevier

    Zhi-Gang Zhang

  26. Targeting cancer stem cell signature gene SMOC-2 Overcomes chemoresistance and inhibits cell proliferation of endometrial carcinoma

    Article • EBioMedicine, February 2019, Elsevier

    Zhi-Gang Zhang

  27. Exosome-mediated secretion of LOXL4 promotes hepatocellular carcinoma cell invasion and metastasis

    Article • Molecular Cancer, January 2019, Springer Science + Business Media

    Zhi-Gang Zhang

  28. THZ1 reveals CDK7-dependent transcriptional addictions in pancreatic cancer

    Article • Oncogene, January 2019, Springer Science + Business Media

    Zhi-Gang Zhang

  29. The histone demethylase KDM4D promotes hepatic fibrogenesis by modulating Toll-like receptor 4 signaling pathway

    Article • EBioMedicine, January 2019, Elsevier

    Zhi-Gang Zhang

  30. Targeting Purinergic Receptor P2Y2 Prevents the Growth of Pancreatic Ductal Adenocarcinoma by Inhibiting Cancer Cell Glycolysis

    Article • Clinical Cancer Research, November 2018, American Association for Cancer Research (AACR)

    Zhi-Gang Zhang

  31. Overexpression of Rac GTPase Activating Protein 1 Contributes to Proliferation of Cancer Cells by Reducing Hippo Signaling to Promote Cytokinesis

    Article • Gastroenterology, October 2018, Elsevier

    Zhi-Gang Zhang

  32. SLIT2/ROBO1 axis contributes to the Warburg effect in osteosarcoma through activation of SRC/ERK/c-MYC/PFKFB2 pathway

    Article • Cell Death and Disease, March 2018, Springer Science + Business Media

    Zhi-Gang Zhang

  33. SRSF10-mediated IL1RAP alternative splicing regulates cervical cancer oncogenesis via mIL1RAP-NF-κB-CD47 axis

    Article • Oncogene, February 2018, Springer Science + Business Media

    Zhi-Gang Zhang

  34. PD-L1 Expression Predicts a Distinct Prognosis in Krukenberg Tumor with Corresponding Origins

    Article • Journal of Immunology Research, January 2018, Hindawi Publishing Corporation

    Zhi-Gang Zhang

  35. FGFRL1 Promotes Ovarian Cancer Progression by Crosstalk with Hedgehog Signaling

    Article • Journal of Immunology Research, January 2018, Hindawi Publishing Corporation

    Zhi-Gang Zhang

  36. Integrin α9 Suppresses Hepatocellular Carcinoma Metastasis by Rho GTPase Signaling

    Article • Journal of Immunology Research, January 2018, Hindawi Publishing Corporation

    Zhi-Gang Zhang

  37. SPARCL1 suppresses osteosarcoma metastasis and recruits macrophages by activation of canonical WNT/β-catenin signaling through stabilization of the WNT–receptor complex

    Article • Oncogene, October 2017, Springer Science + Business Media

    Zhi-Gang Zhang

  38. Increased Serotonin Signaling Contributes to the Warburg Effect in Pancreatic Tumor Cells Under Metabolic Stress and Promotes Growth of Pancreatic Tumors in Mice

    Article • Gastroenterology, July 2017, Elsevier

    Zhi-Gang Zhang

  39. miRNA-218-loaded carboxymethyl chitosan - Tocopherol nanoparticle to suppress the proliferation of gastrointestinal stromal tumor growth

    Article • Materials Science and Engineering C, March 2017, Elsevier

    Zhi-Gang Zhang

  40. Cholesterol Synthetase DHCR24 Induced by Insulin Aggravates Cancer Invasion and Progesterone Resistance in Endometrial Carcinoma

    Article • Scientific Reports, January 2017, Springer Science + Business Media

    Zhi-Gang Zhang

  41. Exemestane Attenuates Hepatic Fibrosis in Rats by Inhibiting Activation of Hepatic Stellate Cells and Promoting the Secretion of Interleukin 10

    Article • Journal of Immunology Research, January 2017, Hindawi Publishing Corporation

    Zhi-Gang Zhang

  42. CCBE1 promotes GIST development through enhancing angiogenesis and mediating resistance to imatinib

    Article • Scientific Reports, August 2016, Nature

    Zhi-Gang Zhang

  43. Long non-coding RNA LINC00628 functions as a gastric cancer suppressor via long-range modulating the expression of cell cycle related genes

    Article • Scientific Reports, June 2016, Springer Science + Business Media

    Zhi-Gang Zhang

  44. Overexpressed EDIL3 predicts poor prognosis and promotes anchorage-independent tumor growth in human pancreatic cancer

    Article • Oncotarget, December 2015, Impact Journals, LLC

    Zhi-Gang Zhang

  45. Mineralocorticoid receptor suppresses cancer progression and the Warburg effect by modulating the miR‐338‐3p‐PKLR axis in hepatocellular carcinoma

    Article • Hepatology, August 2015, Wolters Kluwer Health

    Zhi-Gang Zhang

  46. Elevated Rictor expression is associated with tumor progression and poor prognosis in patients with gastric cancer

    Article • Biochemical and Biophysical Research Communications, August 2015, Elsevier

    Zhi-Gang Zhang

  47. Silencing of MICAL-L2 suppresses malignancy of ovarian cancer by inducing mesenchymal–epithelial transition

    Article • Cancer Letters, July 2015, Elsevier

    Zhi-Gang Zhang

  48. Decreased LKB1 predicts poor prognosis in Pancreatic Ductal Adenocarcinoma

    Article • Scientific Reports, May 2015, Springer Science + Business Media

    Zhi-Gang Zhang

  49. Hepatic stellate cells activated by acidic tumor microenvironment promote the metastasis of hepatocellular carcinoma via osteopontin

    Article • Cancer Letters, January 2015, Elsevier

    Zhi-Gang Zhang

  50. Lysyl oxidase-like 4 (LOXL4) promotes proliferation and metastasis of gastric cancer via FAK/Src pathway

    Article • Journal of Cancer Research and Clinical Oncology, September 2014, Springer Science + Business Media

    Zhi-Gang Zhang

  51. Microfilament regulatory protein MENA increases activity of RhoA and promotes metastasis of hepatocellular carcinoma

    Article • Experimental Cell Research, September 2014, Elsevier

    Zhi-Gang Zhang

  52. DNA methylation-mediated silencing of matricellular protein dermatopontin promotes hepatocellular carcinoma metastasis by α3β1 integrin-Rho GTPase signaling

    Article • Oncotarget, July 2014, Impact Journals, LLC

    Zhi-Gang Zhang

  53. Evaluation of high-risk clinicopathological indicators in gastrointestinal stromal tumors for prognosis and imatinib treatment outcome

    Article • BMC Gastroenterology, June 2014, Springer Science + Business Media

    Zhi-Gang Zhang

  54. Monoamine oxidase A suppresses hepatocellular carcinoma metastasis by inhibiting the adrenergic system and its transactivation of EGFR signaling

    Article • Journal of Hepatology, June 2014, Elsevier

    Zhi-Gang Zhang

  55. LRG1 is an independent prognostic factor for endometrial carcinoma

    Article • Tumor Biology, April 2014, Springer Science + Business Media

    Zhi-Gang Zhang

  56. miR-506 acts as a tumor suppressor by directly targeting the hedgehog pathway transcription factor Gli3 in human cervical cancer

    Article • Oncogene, March 2014, Springer Science + Business Media

    Zhi-Gang Zhang

  57. CTHRC1 Acts as a Prognostic Factor and Promotes Invasiveness of Gastrointestinal Stromal Tumors by Activating Wnt/PCP-Rho Signaling

    Article • Neoplasia, March 2014, Elsevier

    Zhi-Gang Zhang

  58. Lumican Accelerates Wound Healing by Enhancing α2β1 Integrin-Mediated Fibroblast Contractility

    Article • PLOS One, June 2013, PLOS

    Zhi-Gang Zhang

  59. Xiamenmycin Attenuates Hypertrophic Scars by Suppressing Local Inflammation and the Effects of Mechanical Stress

    Article • Journal of Investigative Dermatology, May 2013, Elsevier

    Zhi-Gang Zhang

  60. Serum DKK1 as a protein biomarker for the diagnosis of hepatocellular carcinoma: a large-scale, multicentre study

    Article • The Lancet Oncology, August 2012, Elsevier

    Zhi-Gang Zhang

  61. MCAM is a novel metastasis marker and regulates spreading, apoptosis and invasion of ovarian cancer cells

    Article • Tumor Biology, May 2012, Springer Science + Business Media

    Zhi-Gang Zhang

  62. LASS2 enhances chemosensitivity of breast cancer by counteracting acidic tumor microenvironment through inhibiting activity of V-ATPase proton pump

    Article • Oncogene, May 2012, Springer Science + Business Media

    Zhi-Gang Zhang

  63. Identification and Characterization of an Anti-Fibrotic Benzopyran Compound Isolated from Mangrove-Derived Streptomyces xiamenensis

    Article • Marine Drugs, March 2012, MDPI AG

    Zhi-Gang Zhang

  64. Trophoblast glycoprotein promotes pancreatic ductal adenocarcinoma cell metastasis through Wnt/planar cell polarity signaling

    Article • Molecular Medicine Reports, March 2012, Spandidos Publications

    Zhi-Gang Zhang

  65. Migration of epithelial cells on laminins: RhoA antagonizes directionally persistent migration

    Article • European Journal of Cell Biology, January 2011, Elsevier

    Zhi-Gang Zhang

  66. Integrin α3 subunit regulates events linked to epithelial repair, including keratinocyte migration and protein expression

    Article • Wound Repair and Regeneration, April 2010, Wiley

    Zhi-Gang Zhang

  67. Epigenetic silencing of WIF-1 in hepatocellular carcinomas

    Article • Journal of Cancer Research and Clinical Oncology, January 2010, Springer Science + Business Media

    Zhi-Gang Zhang

  68. Kindlin-1 Is Required for RhoGTPase-Mediated Lamellipodia Formation in Keratinocytes

    Article • American Journal Of Pathology, October 2009, Elsevier

    Zhi-Gang Zhang

  69. Establishment of stable human fibroblast cell lines constitutively expressing active Rho-GTPases

    Article • PROTOPLASMA, December 2006, Springer Science + Business Media

    Zhi-Gang Zhang

  70. Interactions of primary fibroblasts and keratinocytes with extracellular matrix proteins: contribution of  2 1 integrin

    Article • Journal of Cell Science, May 2006, The Company of Biologists

    Zhi-Gang Zhang

  71. Dissociation of the complex between CD151 and laminin-binding integrins permits migration of epithelial cells

    Article • Experimental Cell Research, April 2006, Elsevier

    Zhi-Gang Zhang

  72. Effects of constitutively active GTPases on fibroblast behavior

    Article • Cellular and Molecular Life Sciences, December 2005, Springer Science + Business Media

    Zhi-Gang Zhang

  73. Evidence for Serine/Threonine and Histidine Kinase Activity in the Tobacco Ethylene Receptor Protein NTHK2

    Article • PLANT PHYSIOLOGY, October 2004, American Society of Plant Biologists (ASPB)

    Zhi-Gang Zhang