All Stories

  1. Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis

    Article • PLoS Biology, December 2020, PLOS

    Dr Zandrea Ambrose, Itay Rousso, Juuan Perilla

  2. Truncated CPSF6 Forms Higher-Order Complexes That Bind and Disrupt HIV-1 Capsid

    Article • Journal of Virology, April 2018, ASM Journals

    Dr Zandrea Ambrose

  3. Interferon-Inducible CD169/Siglec1 Attenuates Anti-HIV-1 Effects of Alpha Interferon

    Article • Journal of Virology, August 2017, ASM Journals

    Dr Suryaram Gummuluru, Dr Zandrea Ambrose

  4. A spatio-temporal assessment of simian/human immunodeficiency virus (SHIV) evolution reveals a highly dynamic process within the host

    Article • PLoS Pathogens, May 2017, PLOS

    Dr Zandrea Ambrose

  5. Establishment and Reversal of HIV-1 Latency in Naive and Central Memory CD4+T CellsIn Vitro

    Article • Journal of Virology, June 2016, ASM Journals

    Dr Zandrea Ambrose

  6. Rilpivirine and Doravirine have complementary efficacies against NNRTI-Resistant HIV-1 mutants

    Article • JAIDS Journal of Acquired Immune Deficiency Syndromes, April 2016, Wolters Kluwer Health

    Dr Zandrea Ambrose

  7. Rilpivirine analogs potently inhibit drug-resistant HIV-1 mutants

    Article • Retrovirology, February 2016, Springer Science + Business Media

    Dr Zandrea Ambrose

  8. No compartmentalization of RT-SHIV in blood vs. tissues

    Article • Retrovirology, November 2015, Springer Science + Business Media

    Dr Zandrea Ambrose

  9. Difficulty in detection of resistant virus in RT-SHIV infected macaques treated with RPV LA

    Article • Antimicrobial Agents and Chemotherapy, October 2015, ASM Journals

    Dr Zandrea Ambrose

  10. Expression of reporter genes in SIV can allow visualization of infected cells in live animals

    Article • Journal of General Virology, October 2015, Society for General Microbiology

    Dr Zandrea Ambrose

  11. Systematic Analysis of Intracellular Trafficking Motifs Located within the Cytoplasmic Domain of Simian Immunodeficiency Virus Glycoprotein gp41

    Article • PLoS ONE, December 2014, PLOS

    Dr Zandrea Ambrose

  12. Correlative Imaging and Cryo-FIB Processing for Direct Visualization of HIV-1 Infection

    Article • Microscopy and Microanalysis, August 2014, Cambridge University Press

    Dr Zandrea Ambrose

  13. Multiple genes associated with inflammation are upregulated in tissues during RT-SHIV infection

    Article • Journal of Medical Primatology, May 2014, Wiley

    Dr Zandrea Ambrose

  14. HIV-1 uncoating: connection to nuclear entry and regulation by host proteins

    Article • Virology, April 2014, Elsevier

    Dr Zandrea Ambrose

  15. RT-SHIV can be suppressed by antiretroviral therapy and can be used to study viral latency

    Article • PLoS ONE, December 2013, PLOS

    Dr Zandrea Ambrose

  16. Correction

    Article • Biophysical Journal, April 2013, Elsevier

    Dr Zandrea Ambrose

  17. Novel imaging assay reveals biphasic capsid uncoating of HIV-1

    Article • Retrovirology, January 2013, Springer Science + Business Media

    Dr Zandrea Ambrose

  18. Ultrasensitive Allele-Specific PCR Reveals Rare Preexisting Drug-Resistant Variants

    Article • Journal of Virology, August 2012, ASM Journals

    Professor John M Coffin, Dr Zandrea Ambrose

  19. Use of Animal Models for Anti-HIV Drug Development

    Article • March 2012, IntechOpen

    Dr Zandrea Ambrose

  20. Identification of HIV Inhibitors Guided by Free Energy Perturbation Calculations

    Article • Current Pharmaceutical Design, March 2012, Bentham Science Publishers

    Dr Zandrea Ambrose

  21. N74D HIV-1 capsid mutant has increased dependence on cyclophilin A, cannot replicate in macrophages

    Article • Journal of Virology, February 2012, ASM Journals

    Dr Zandrea Ambrose

  22. Intact HIV-1 capsid cores were directly visualized in the cytoplasm of human cells

    Article • Structure, November 2011, Elsevier

    Dr Zandrea Ambrose

  23. ART did not decrease genetic diversity of RT-SHIV

    Article • Journal of Virology, November 2010, ASM Journals

    Professor John M Coffin, Dr Zandrea Ambrose

  24. CPSF6 binds HIV-1 capsid and cytoplasmic expression restricts infection

    Article • Cell Host & Microbe, March 2010, Elsevier

    Dr Yuan Li, Professor John M Coffin, Dr Zandrea Ambrose

  25. RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy

    Article • Retrovirology, November 2009, Springer Science + Business Media

    Professor John M Coffin, Dr Zandrea Ambrose

  26. The Nucleoside Analogue D-carba T Blocks HIV-1 Reverse Transcription

    Article • Journal of Medicinal Chemistry, September 2009, American Chemical Society (ACS)

    Dr Zandrea Ambrose

  27. HIV-1 containing SIV Vif replicated in pigtailed macaques

    Article • Proceedings of the National Academy of Sciences, March 2009, Proceedings of the National Academy of Sciences

    Dr Zandrea Ambrose

  28. HIV-1 with I132M in RT decreases nucleotide selectivity

    Article • Journal of Virology, February 2009, ASM Journals

    Dr Zandrea Ambrose

  29. The use of animal models in HIV/AIDS therapeutics and pre-exposure prophylaxis

    Article • Future HIV Therapy, July 2008, Future Medicine

    Dr Zandrea Ambrose

  30. A candidate microbicide sensitized macaques to SIV infection upon second exposure

    Article • Journal of Virology, April 2008, ASM Journals

    Dr Zandrea Ambrose

  31. Study of RT inhibitor resistance in a macaque model of HIV/AIDS

    Article • Journal of Virology, September 2007, ASM Journals

    Professor John M Coffin, Dr Zandrea Ambrose

  32. A novel HIV-1 RT inhibitor causes delayed DNA chain termination

    Article • Journal of Molecular Biology, August 2007, Elsevier

    Dr Zandrea Ambrose

  33. The use of animal models in HIV/AIDS research

    Article • Trends in Biotechnology, August 2007, Elsevier

    Dr Zandrea Ambrose

  34. NNRTI resistance can be caused by mutations in the RT p51 subunit, far from the active site

    Article • Biochemical Journal, May 2007, Portland Press Ltd.

    Dr Zandrea Ambrose

  35. More RT in HIV-1 requires more NNRTI to inhibit infection

    Article • Journal of Virology, March 2006, ASM Journals

    Dr Zandrea Ambrose

  36. SIV containing HIV-1 RT can be inhibited by anti-HIV-1 RT inhibitors

    Article • Journal of Virology, December 2004, ASM Journals

    Professor John M Coffin, Dr Zandrea Ambrose

  37. Mucosal vaccination enhanced anti-SIV/HIV immune responses and reduced viral infection

    Article • Virology, March 2003, Elsevier

    Dr Zandrea Ambrose

  38. SIV/HIV replicates at the initial site of infection (mucosa) before spreading to other tissues

    Article • Journal of Virology, September 2001, ASM Journals

    Dr Zandrea Ambrose