All Stories

  1. ChemInform Abstract: A Convenient Synthesis of 2-Mercapto-oxazoles via β-Ketoazide and Its Application to a Key Intermediate of PI3Kγ Inhibitors.

    Article • ChemInform, January 2014, Wiley

    Yusuke Oka

  2. Discovery of N-{5-[3-(3-hydroxypiperidin-1-yl)-1,2,4-oxadiazol-5-yl]-4-methyl-1,3-thiazol-2-yl}acetamide (TASP0415914) as an orally potent phosphoinositide 3-kinase γ inhibitor for the treatment of inflammatory diseases

    Article • Bioorganic & Medicinal Chemistry, December 2013, Elsevier

    Yusuke Oka

  3. A CONVENIENT SYNTHESIS OF 2-MERCAPTO-OXAZOLES VIA β-KETOAZIDE AND ITS APPLICATION TO A KEY INTERMEDIATE OF PI3Kγ INHIBITORS

    Article • Heterocycles, January 2013, Japan Institute of Heterocyclic Chemistry

    Yusuke Oka

  4. Discovery and optimization of a series of 2-aminothiazole-oxazoles as potent phosphoinositide 3-kinase γ inhibitors

    Article • Bioorganic & Medicinal Chemistry Letters, December 2012, Elsevier

    Yusuke Oka

  5. Ring-fused pyrazole derivatives as potent inhibitors of lymphocyte-specific kinase (Lck): Structure, synthesis, and SAR

    Article • Bioorganic & Medicinal Chemistry Letters, January 2010, Elsevier

    Yusuke Oka

  6. ChemInform Abstract: Acylzirconocene Chloride: Formation of Carbocycles by Palladium-Catalyzed Cascade Reaction.

    Article • ChemInform, February 2008, Wiley

    Yusuke Oka

  7. Acylzirconocene chloride: Formation of carbocycles by palladium-catalyzed cascade reaction

    Article • Journal of Organometallic Chemistry, October 2007, Elsevier

    Yusuke Oka

  8. Cyclization/Acylation Reactions by Nickel-Catalyzed Reactions of 1,6-Ynal and 1,6-Enyne Derivatives with Acylzirconocene Chloride.

    Article • ChemInform, July 2006, Wiley

    Yusuke Oka

  9. Cyclization/acylation reactions by nickel-catalyzed reactions of 1,6-ynal and 1,6-enyne derivatives with acylzirconocene chloride

    Article • Tetrahedron Letters, March 2006, Elsevier

    Yusuke Oka

  10. Palladium-Catalyzed Reaction of Acylzirconocene Chloride and Stereoselective Formation of Bicyclo[3.3.0] Compounds.

    Article • ChemInform, April 2003, Wiley

    Yusuke Oka

  11. Palladium-Catalyzed Reaction of Acylzirconocene Chloride and Stereoselective Formation of Bicyclo[3.3.0] Compounds

    Article • Organic Letters, November 2002, American Chemical Society (ACS)

    Yusuke Oka