All Stories

  1. Total Synthesis of Antrimycins A and D

    Article • Organic Letters, October 2026, American Chemical Society (ACS)

    Dr Yusuke Minato

  2. Matching-adjusted comparison of the effectiveness and safety of Ensitrelvir versus Remdesivir for high-risk, hospitalized patients with non-severe COVID-19 in Japan

    Article • Journal of Infection and Chemotherapy, August 2026, Elsevier

    Dr Yusuke Minato

  3. Integrated analysis of transposon insertion sequencing and pangenome reveals core and lineage-specific essential genes in Mycobacterium avium subsp. hominissuis

    Article • Microbial Genomics, June 2026, Society for General Microbiology

    Dr Yusuke Minato

  4. Identification of novel antimicrobial drug combinations with synergistic activity against Mycobacterium abscessus

    Article • June 2026, Society for General Microbiology

    Dr Yusuke Minato

  5. Transposon insertion sequencing identifies genetic determinants of intrinsic rifamycin resistance in Mycobacterium abscessus

    Article • June 2026, openRxiv

    Dr Yusuke Minato

  6. Establishment of an in vivo -based assay using a silkworm infection model for phenotypic evaluation of antimicrobial drug combinations against Mycobacterium abscessus

    Article • Antimicrobial Agents and Chemotherapy, February 2026, ASM Journals

    Dr Yusuke Minato

  7. Diagnostic utility of quantitative interferon-gamma release assays in elderly patients with tuberculosis

    Article • Microbiology Spectrum, February 2026, ASM Journals

    Dr Yusuke Minato

  8. Nosocomial Mycobacterium lentiflavum colonization and infection cluster at a Japanese tertiary care center: report of an outbreak/pseudo-outbreak investigation

    Article • Antimicrobial Stewardship & Healthcare Epidemiology, January 2026, Cambridge University Press

    Dr Yusuke Minato

  9. Functional genomics reveals strain-specific genetic requirements conferring hypoxic growth in Mycobacterium intracellulare

    Article • eLife, December 2025, eLife

    Dr Yusuke Minato

  10. Functional genomics reveals strain-specific genetic requirements conferring hypoxic growth in Mycobacterium intracellulare

    Article • eLife, December 2025, eLife

    Dr Yusuke Minato

  11. Integrated analysis of Tn-Seq and pangenome reveals core and lineage-specific essential genes in Mycobacterium avium subsp. hominissuis

    Article • October 2025, Cold Spring Harbor Laboratory Press

    Dr Yusuke Minato

  12. Trends in nontuberculous mycobacterial disease mortality based on 2000-2022 data from 83 countries

    Article • International Journal of Infectious Diseases, September 2025, Elsevier

    Dr Yusuke Minato

  13. Clinical outcomes of flomoxef versus cefmetazole in hospitalized patients with urinary tract infections: combined retrospective analyses of two real-world databases and in vitro data

    Article • BMC Medicine, July 2025, Springer Science + Business Media

    Dr Yusuke Minato

  14. Clinical outcomes of flomoxef versus cefmetazole in hospitalized patients with urinary tract infections: Combined retrospective analyses of two real-world databases andin vitrodata

    Article • July 2024, Cold Spring Harbor Laboratory Press

    Dr Yusuke Minato

  15. Functional genomics reveals the mechanism of hypoxic adaptation in nontuberculous mycobacteria

    Article • July 2024, eLife

    Dr Yusuke Minato

  16. A duplexed CRISPRi-based approach to predict synergistic antibiotic targets in Escherichia coli

    Article • May 2024, openRxiv

    Dr Yusuke Minato

  17. Functional genomics reveals strain-specific genetic requirements conferring hypoxic growth in Mycobacterium intracellulare

    Article • May 2024, openRxiv

    Dr Yusuke Minato

  18. Molecular Aggregation Strategy for Inhibiting DNases

    Article • JACS Au, April 2024, American Chemical Society (ACS)

    Dr Yusuke Minato

  19. Synthesis of macrocyclic nucleoside antibacterials and their interactions with MraY

    Article • Nature Communications, December 2022, Springer Science + Business Media

    Dr Yusuke Minato

  20. Synthesis of capuramycin and its analogues via a Ferrier-type I reaction and their biological evaluation

    Article • Bioorganic & Medicinal Chemistry, November 2022, Elsevier

    Dr Yusuke Minato

  21. Cephem‐Pyrazinoic Acid Conjugates: Circumventing Resistance in Mycobacterium tuberculosis

    Article • Chemistry - A European Journal, July 2022, Wiley

    Dr Yusuke Minato

  22. Design, synthesis and conformation-activity relationship analysis of LNA/BNA-type 5′-O-aminoribosyluridine as MraY inhibitors

    Article • Bioorganic & Medicinal Chemistry, July 2022, Elsevier

    Dr Yusuke Minato

  23. Pyrazinamide Susceptibility Is Driven by Activation of the SigE-Dependent Cell Envelope Stress Response in Mycobacterium tuberculosis

    Article • mBio, February 2022, ASM Journals

    Dr Yusuke Minato

  24. Attempt of thyX gene silencing and construction of a thyX deleted clone in a Mycobacterium bovis BCG

    Article • Microbiology and Immunology, October 2021, Wiley

    Dr Yusuke Minato

  25. Functional and Structural Characterization of Acquired 16S rRNA Methyltransferase NpmB1 Conferring Pan-Aminoglycoside Resistance

    Article • Antimicrobial Agents and Chemotherapy, September 2021, ASM Journals

    Dr Yusuke Minato

  26. Trends in hepatitis C virus‐associated mortality rates in Japan, 1998–2017

    Article • Journal of Gastroenterology and Hepatology, May 2021, Wiley

    Dr Yusuke Minato

  27. Pyrazinamide action is driven by the cell envelope stress response in Mycobacterium tuberculosis

    Article • February 2021, Cold Spring Harbor Laboratory Press

    Dr Yusuke Minato

  28. Genome-wide identification of essential genes in Mycobacterium intracellulare by transposon sequencing — Implication for metabolic remodeling

    Article • Scientific Reports, March 2020, Springer Science + Business Media

    Dr Yusuke Minato

  29. Genomewide Assessment of Mycobacterium tuberculosis Conditionally Essential Metabolic Pathways

    Article • mSystems, June 2019, ASM Journals

    Dr Yusuke Minato

  30. Comprehensive analysis of resistance-nodulation-cell division superfamily (RND) efflux pumps from Serratia marcescens, Db10

    Article • Scientific Reports, March 2019, Springer Science + Business Media

    Dr Yusuke Minato

  31. Genome-wide assessment of Mycobacterium tuberculosis conditionally essential metabolic pathways

    Article • January 2019, Cold Spring Harbor Laboratory Press

    Dr Yusuke Minato

  32. Methionine Antagonizes para-Aminosalicylic Acid Activity via Affecting Folate Precursor Biosynthesis in Mycobacterium tuberculosis

    Article • Frontiers in Cellular and Infection Microbiology, November 2018, Frontiers

    Dr Yusuke Minato

  33. Trends in incidence and mortality of tuberculosis in Japan: a population-based study, 1997–2016

    Article • Epidemiology and Infection, November 2018, Cambridge University Press

    Dr Yusuke Minato

  34. Methionine antagonizes para-aminosalicylic acid activity via affecting folate precursor biosynthesis pathway in Mycobacterium tuberculosis

    Article • May 2018, Cold Spring Harbor Laboratory Press

    Dr Yusuke Minato

  35. Mutual potentiation drives synergy between trimethoprim and sulfamethoxazole

    Article • Nature Communications, March 2018, Nature

    Dr Yusuke Minato

  36. Metabolomics of Vibrio cholerae

    Article • January 2018, Springer Science + Business Media

    Dr Yusuke Minato

  37. Subversion of Metabolic Wasting as the Mechanism for folM-Linked Sulfamethoxazole Resistance

    Article • mBio, November 2017, ASM Journals

    Professor Anthony David Baughn, Dr Yusuke Minato

  38. Targeting intracellular p-aminobenzoic acid production potentiates the anti-tubercular action of antifolates

    Article • Scientific Reports, December 2016, Nature

    Dr Yusuke Minato

  39. Long-Chain Fatty Acyl Coenzyme A Ligase FadD2 Mediates Intrinsic Pyrazinamide Resistance in Mycobacterium tuberculosis

    Article • Antimicrobial Agents and Chemotherapy, November 2016, ASM Journals

    Professor Anthony David Baughn, Dr Yusuke Minato

  40. The Na+-Translocating NADH:Quinone Oxidoreductase Enhances Oxidative Stress in the Cytoplasm of Vibrio cholerae

    Article • Journal of Bacteriology, June 2016, ASM Journals

    Dr Yusuke Minato

  41. Mycobacterium tuberculosis Folate Metabolism and the Mechanistic Basis forpara-Aminosalicylic Acid Susceptibility and Resistance

    Article • Antimicrobial Agents and Chemotherapy, June 2015, ASM Journals

    Professor Anthony David Baughn, Dr Yusuke Minato

  42. Characterization of MATE-Type Multidrug Efflux Pumps from Klebsiella pneumoniae MGH78578

    Article • PLOS One, March 2015, PLOS

    Dr Yusuke Minato

  43. Roles of the Sodium-Translocating NADH:Quinone Oxidoreductase (Na+-NQR) on Vibrio cholerae Metabolism, Motility and Osmotic Stress Resistance

    Article • PLOS One, May 2014, PLOS

    Dr Yusuke Minato

  44. Inhibition of the sodium-translocating NADH-ubiquinone oxidoreductase [Na+-NQR] decreases cholera toxin production in Vibrio cholerae O1 at the late exponential growth phase

    Article • Microbial Pathogenesis, January 2014, Elsevier

    Dr Yusuke Minato

  45. Na+/H+Antiport Is Essential for Yersinia pestis Virulence

    Article • Infection and Immunity, June 2013, ASM Journals

    Dr Yusuke Minato

  46. Malonate Inhibits Virulence Gene Expression in Vibrio cholerae

    Article • PLOS One, May 2013, PLOS

    Dr Yusuke Minato

  47. Central metabolism controls transcription of a virulence gene regulator in Vibrio cholerae

    Article • Microbiology, February 2013, Society for General Microbiology

    Dr Yusuke Minato

  48. TolC Affects Virulence Gene Expression in Vibrio cholerae

    Article • Journal of Bacteriology, August 2011, ASM Journals

    Dr Yusuke Minato

  49. Functional Gene Cloning and Characterization of the SsmE Multidrug Efflux Pump from Serratia marcescens

    Article • Biological and Pharmaceutical Bulletin, January 2008, Pharmaceutical Society of Japan

    Dr Yusuke Minato

  50. SmdAB, a Heterodimeric ABC-Type Multidrug Efflux Pump, in Serratia marcescens

    Article • Journal of Bacteriology, November 2007, ASM Journals

    Dr Yusuke Minato

  51. Molecular Cloning and Characterization of a Multidrug Efflux Pump, SmfY, from Serratia marcescens

    Article • Biological and Pharmaceutical Bulletin, January 2007, Pharmaceutical Society of Japan

    Dr Yusuke Minato