Contact

All Stories

  1. A Chiroptical Switch Owing to Mercury-Crosslinked Ribonucleosides

    Article • Analytical Chemistry, August 2026, American Chemical Society (ACS)

    Professor Yoshiyuki Tanaka

  2. Repurposing caspofungin as a small-molecule inhibitor of Clostridium perfringens α-toxin for treatment of gas gangrene

    Article • Communications Medicine, April 2026, Springer Science + Business Media

    Professor Yoshiyuki Tanaka

  3. Capturing a glycosylase reaction intermediate in DNA repair by freeze-trapping of a pH-responsive hOGG1 mutant

    Article • Nucleic Acids Research, July 2025, Oxford University Press (OUP)

    Professor Yoshiyuki Tanaka

  4. DNA Duplex Containing Ag+-Mediated Cytosine–Cytosine Base Pairs as a Catalyst Precursor for the 4-Nitrophenol Reduction with NaBH4

    Article • Inorganic Chemistry, November 2024, American Chemical Society (ACS)

    Professor Yoshiyuki Tanaka

  5. Hyper-mobile Water and Raman 2900 cm–1 Peak Band of Water Observed around Backbone Phosphates of Double Stranded DNA by High-Resolution Spectroscopies and MD Structural Feature Analysis of Water

    Article • The Journal of Physical Chemistry B, December 2022, American Chemical Society (ACS)

    Professor Yoshiyuki Tanaka

  6. N′1,N′4-bis(2-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)ethylidene)succinohydrazide

    Article • Molbank, August 2022, MDPI AG

    Professor Yoshiyuki Tanaka

  7. Physicochemical Characterization of the Catalytic Unit of Hammerhead Ribozyme and Its Relationship with the Catalytic Activity

    Article • Biophysica, August 2022, MDPI AG

    Professor Yoshiyuki Tanaka

  8. Synthesis of a Cyclic Dinucleotide Analogue with Ambiguous Bases, 5-Aminoimidazole-4-carboxamide

    Article • The Journal of Organic Chemistry, October 2021, American Chemical Society (ACS)

    Professor Yoshiyuki Tanaka

  9. Chemical reduction of Ag+ to Ag employing organic electron donors: evaluation of the effect of Ag+-mediated cytosine–cytosine base pairing on the aggregation of Ag nanoparticles

    Article • Dalton Transactions, January 2021, Royal Society of Chemistry

    Professor Yoshiyuki Tanaka

  10. Effect of cytosine–Ag+–cytosine base pairing on the redox potential of the Ag+/Ag couple and the chemical reduction of Ag+ to Ag by tetrathiafulvalene

    Article • Dalton Transactions, January 2021, Royal Society of Chemistry

    Professor Yoshiyuki Tanaka

  11. Electrical conductance measurement of HgII-mediated DNA duplex in buffered aqueous solution

    Article • Nucleosides Nucleotides & Nucleic Acids, April 2020, Taylor & Francis

    Professor Yoshiyuki Tanaka

  12. QM and QM/MM umbrella sampling MD study of the formation of Hg(II)–thymine bond: Model for evaluation of the reaction energy profiles in solutions with constant pH

    Article • Journal of Computational Chemistry, March 2020, Wiley

    Professor Yoshiyuki Tanaka

  13. Structure–activity relationship of pseudoknot-type hammerhead ribozyme reveals key structural elements for enhanced catalytic activity†

    Article • Nucleosides Nucleotides & Nucleic Acids, October 2019, Taylor & Francis

    Professor Yoshiyuki Tanaka

  14. NMR spectroscopic characterization of a model RNA duplex reflecting the core sequence of hammerhead ribozymes

    Article • Nucleosides Nucleotides & Nucleic Acids, June 2018, Taylor & Francis

    Professor Yoshiyuki Tanaka, Yoshikazu Hattori

  15. Metallo-DNA nano wire

    Article • Nature Chemistry, July 2017, Springer Science + Business Media

    Professor Yoshiyuki Tanaka

  16. The mechanism of the glycosylase reaction with hOGG1 base-excision repair enzyme: concerted effect of Lys249 and Asp268 during excision of 8-oxoguanine

    Article • Nucleic Acids Research, March 2017, Oxford University Press (OUP)

    Professor Yoshiyuki Tanaka

  17. Hg II /Ag I -mediated base pairs and their NMR spectroscopic studies

    Article • Inorganica Chimica Acta, October 2016, Elsevier

    Professor Yoshiyuki Tanaka

  18. The effect of chemical modification of DNA base on binding of Hg II and Ag I in metal-mediated base pairs

    Article • Inorganica Chimica Acta, October 2016, Elsevier

    Professor Yoshiyuki Tanaka

  19. Practical synthesis of 4′-selenopurine nucleosides by combining chlorinated purines and ‘armed’ 4-selenosugar

    Article • Tetrahedron, October 2016, Elsevier

    Professor Yoshiyuki Tanaka

  20. Structure Determination of an AgI-Mediated Cytosine-Cytosine Base Pair within DNA Duplex in Solution with1H/15N/109Ag NMR Spectroscopy

    Article • Chemistry - A European Journal, August 2016, Wiley

    Professor Yoshiyuki Tanaka

  21. Benchmark Theoretical and Experimental Study on 15N NMR Shifts of Oxidatively Damaged Guanine

    Article • The Journal of Physical Chemistry B, February 2016, American Chemical Society (ACS)

    Professor Yoshiyuki Tanaka

  22. Exploring a DNA Sequence for the Three-Dimensional Structure Determination of a Silver(I)-Mediated C-C Base Pair in a DNA Duplex By1H NMR Spectroscopy

    Article • Nucleosides Nucleotides & Nucleic Acids, November 2015, Taylor & Francis

    Professor Yoshiyuki Tanaka

  23. High‐Resolution Crystal Structure of a Silver(I)–RNA Hybrid Duplex Containing Watson–Crick‐like CSilver(I)C Metallo‐Base Pairs

    Article • Angewandte Chemie, October 2015, Wiley

    Professor Yoshiyuki Tanaka

  24. Direct detection of the mercury–nitrogen bond in the thymine–HgII–thymine base-pair with 199Hg NMR spectroscopy

    Article • Chemical Communications, January 2015, Royal Society of Chemistry

    Dr Chojiro Kojima, Professor Yoshiyuki Tanaka, Professor Matthias Bickelhaupt

  25. Structures, physicochemical properties, and applications of T–HgII–T, C–AgI–C, and other metallo-base-pairs

    Article • Chemical Communications, January 2015, Royal Society of Chemistry

    Professor Yoshiyuki Tanaka

  26. Pseudoknot Interaction-Mediated Activation of Type I Hammerhead Ribozyme: A New Class of Gene-Therapeutic Agents

    Article • Nucleosides Nucleotides & Nucleic Acids, June 2014, Taylor & Francis

    Professor Yoshiyuki Tanaka

  27. Theoretical and Experimental Study of Charge Transfer through DNA: Impact of Mercury Mediated T-Hg-T Base Pair

    Article • The Journal of Physical Chemistry B, May 2014, American Chemical Society (ACS)

    Professor Matthias Bickelhaupt, Professor Yoshiyuki Tanaka

  28. Structure of metallo-dna in solution

    Article • March 2014, Protein Data Bank, Rutgers University

    Professor Yoshiyuki Tanaka

  29. Crystal Structure of Metallo DNA Duplex Containing Consecutive Watson-Crick-like T-HgII-T Base Pairs

    Article • Angewandte Chemie, January 2014, Wiley

    Professor Yoshiyuki Tanaka

  30. Crystal Structure of Metallo DNA Duplex Containing Consecutive Watson-Crick-like T-HgII-T Base Pairs

    Article • Angewandte Chemie, January 2014, Wiley

    Professor Yoshiyuki Tanaka

  31. The activation of N-glycosidic bond cleavage performed by base-excision repair enzyme hOGG1; theoretical study of the role of Lys 249 residue in activation of G, OxoG and FapyG

    Article • RSC Advances, January 2014, Royal Society of Chemistry

    Professor Yoshiyuki Tanaka

  32. Hg2+-Trapping Beads: Hg2+-Specific Recognition through Thymine–Hg(II)–Thymine Base Pairing

    Article • Chemical and Pharmaceutical Bulletin, January 2014, Pharmaceutical Society of Japan

    Professor Yoshiyuki Tanaka

  33. The structure of metallo-DNA with consecutive thymine-HgII-thymine base pairs explains positive entropy for the metallo base pair formation

    Article • Nucleic Acids Research, December 2013, Oxford University Press (OUP)

    Professor Yoshiyuki Tanaka

  34. ChemInform Abstract: Organocatalytic Functionalization of Heteroaromatic N-Oxides with C-Nucleophiles Using in situ Generated Onium Amide Bases.

    Article • ChemInform, October 2013, Wiley

    Professor Yoshiyuki Tanaka

  35. ChemInform Abstract: Carboxylation of Alkynylsilanes with Carbon Dioxide Mediated by Cesium Fluoride in DMSO.

    Article • ChemInform, September 2013, Wiley

    Professor Yoshiyuki Tanaka

  36. Formation of a Thymine-HgII-Thymine Metal-Mediated DNA Base Pair: Proposal and Theoretical Calculation of the Reaction Pathway

    Article • Chemistry - A European Journal, June 2013, Wiley

    Dr Chojiro Kojima, Professor Yoshiyuki Tanaka

  37. Carboxylation of alkynylsilanes with carbon dioxide mediated by cesium fluoride in DMSO

    Article • Organic & Biomolecular Chemistry, January 2013, Royal Society of Chemistry

    Kiyofumi Inamoto, Professor Yoshiyuki Tanaka

  38. Organocatalytic functionalization of heteroaromatic N-oxides with C-nucleophiles using in situ generated onium amide bases

    Article • Organic & Biomolecular Chemistry, January 2013, Royal Society of Chemistry

    Kiyofumi Inamoto, Professor Yoshiyuki Tanaka

  39. Mercury and DNA

    Article • January 2013, Springer Science + Business Media

    Professor Yoshiyuki Tanaka

  40. Thermodynamic and structural properties of the specific binding between Ag+ ion and C:C mismatched base pair in duplex DNA to form C–Ag–C metal-mediated base pair

    Article • Biochimie, November 2012, Elsevier

    Professor Yoshiyuki Tanaka

  41. Pyramidalization of the Glycosidic Nitrogen Provides the Way for Efficient Cleavage of the N-Glycosidic Bond of 8-OxoG with the hOGG1 DNA Repair Protein

    Article • The Journal of Physical Chemistry B, October 2012, American Chemical Society (ACS)

    Professor Yoshiyuki Tanaka

  42. Detection of Mercury–TpT Dinucleotide Binding by Raman Spectra: A Computational Study

    Article • The Journal of Physical Chemistry A, August 2012, American Chemical Society (ACS)

    Professor Yoshiyuki Tanaka

  43. Structure Formation and Catalytic Activity of DNA Dissolved in Organic Solvents

    Article • Angewandte Chemie, May 2012, Wiley

    Professor Yoshiyuki Tanaka

  44. Raman spectroscopic detection of the T-HgII-T base pair and the ionic characteristics of mercury

    Article • Nucleic Acids Research, March 2012, Oxford University Press (OUP)

    Professor Yoshiyuki Tanaka

  45. ChemInform Abstract: Binding of Metal Ions by Pyrimidine Base Pairs in DNA Duplexes

    Article • ChemInform, February 2012, Wiley

    Professor Yoshiyuki Tanaka

  46. Site-specific isotope labeling of long RNA for structural and mechanistic studies

    Article • Nucleic Acids Research, November 2011, Oxford University Press (OUP)

    Professor Yoshiyuki Tanaka

  47. On the role of mercury in the non-covalent stabilisation of consecutive U–HgII–U metal-mediated nucleic acid base pairs: metallophilic attraction enters the world of nucleic acids

    Article • Physical Chemistry Chemical Physics, January 2011, Royal Society of Chemistry

    Michal Straka, Professor Yoshiyuki Tanaka

  48. Binding of metal ions by pyrimidine base pairs in DNA duplexes

    Article • Chemical Society Reviews, January 2011, Royal Society of Chemistry

    Professor Yoshiyuki Tanaka

  49. Nitrogen-15 NMR Spectroscopy of Sugar Sensor with B–N Interaction as a Key Regulator of Colorimetric Signals

    Article • Chemistry Letters, November 2010, The Chemical Society of Japan

    Professor Yoshiyuki Tanaka

  50. ChemInform Abstract: Nitrogen-15 NMR Spectroscopy of N-Metalated Nucleic Acids: Insights into15N NMR Parameters and N-Metal Bonds

    Article • ChemInform, February 2009, Wiley

    Professor Yoshiyuki Tanaka

  51. Spectroscopic analysis of the pyrimidine(6–4)pyrimidone photoproduct: insights into the (6–4) photolyase reaction

    Article • Organic & Biomolecular Chemistry, January 2009, Royal Society of Chemistry

    Professor Yoshiyuki Tanaka

  52. Specific interactions between silver(i) ions and cytosine–cytosine pairs in DNA duplexes

    Article • Chemical Communications, January 2008, Royal Society of Chemistry

    Professor Yoshiyuki Tanaka

  53. Nitrogen-15 NMR spectroscopy of N-metallated nucleic acids: insights into 15N NMR parameters and N–metal bonds

    Article • Dalton Transactions, January 2008, Royal Society of Chemistry

    Professor Yoshiyuki Tanaka

  54. 新規ナノデバイス材料としてのメタロDNA分子の構造

    Article • Seibutsu Butsuri, January 2008, Biophysical Society of Japan

    Professor Yoshiyuki Tanaka

  55. 15 N− 15 N J -Coupling Across Hg II :  Direct Observation of Hg II -Mediated T−T Base Pairs in a DNA Duplex

    Article • Journal of the American Chemical Society, January 2007, American Chemical Society (ACS)

    Dr Chojiro Kojima, Professor Yoshiyuki Tanaka

  56. NMR Spectroscopic Observation of a Metal-Free Acetylide Anion

    Article • Chemistry - An Asian Journal, October 2006, Wiley

    Professor Yoshiyuki Tanaka

  57. NMR Spectroscopic Study of a DNA Duplex with Mercury-Mediated T-T Base Pairs

    Article • Nucleosides Nucleotides & Nucleic Acids, June 2006, Taylor & Francis

    Dr Chojiro Kojima, Professor Yoshiyuki Tanaka

  58. Formation of a Complex of 5,10,15,20-Tetrakis( N -methylpyridinium-4-yl)-21 H ,23 H -porphyrin with G-Quadruplex DNA †

    Article • Biochemistry, June 2006, American Chemical Society (ACS)

    Professor Yoshiyuki Tanaka

  59. Mercury II -Mediated Formation of Thymine−Hg II −Thymine Base Pairs in DNA Duplexes

    Article • Journal of the American Chemical Society, February 2006, American Chemical Society (ACS)

    Professor Yoshiyuki Tanaka

  60. Organic Synthesis Using Organic Superbase

    Article • ChemInform, October 2005, Wiley

    Professor Yoshiyuki Tanaka

  61. Detection of RNA nucleobase metalation by NMR spectroscopy

    Article • Chemical Communications, January 2005, Royal Society of Chemistry

    Professor Yoshiyuki Tanaka

  62. Nature of the Chemical Bond Formed with the Structural Metal Ion at the A9/G10.1 Motif Derived from Hammerhead Ribozymes

    Article • Journal of the American Chemical Society, January 2004, American Chemical Society (ACS)

    Dr Chojiro Kojima, Professor Yoshiyuki Tanaka

  63. Spectroscopic Analyses of the Interaction Between Hammerhead Ribozymes and Metal Ions

    Article • ChemInform, September 2003, Wiley

    Professor Yoshiyuki Tanaka

  64. Spectroscopic Analyses of the Interaction between Hammerhead Ribozymes and Metal Ions

    Article • YAKUGAKU ZASSHI, January 2003, Pharmaceutical Society of Japan

    Professor Yoshiyuki Tanaka

  65. Divalent Cation Binding to the Well-Conserved Tandem G-A Pairs and Flanking C-G Pair in Hammerhead Ribozyme as Revealed by Heteronuclear NMR Spectroscopy

    Article • Phosphorus Sulfur and Silicon and the Related Elements, August 2002, Taylor & Francis

    Professor Yoshiyuki Tanaka

  66. A Reappraisal, Based on 31 P NMR, of the Direct Coordination of a Metal Ion with the Phosphoryl Oxygen at the Cleavage Site of a Hammerhead Ribozyme

    Article • Journal of the American Chemical Society, July 2002, American Chemical Society (ACS)

    Professor Yoshiyuki Tanaka

  67. Identification of the Metal Ion Binding Site on an RNA Motif from Hammerhead Ribozymes Using 15 N NMR Spectroscopy

    Article • Journal of the American Chemical Society, May 2002, American Chemical Society (ACS)

    Dr Chojiro Kojima, Professor Yoshiyuki Tanaka

  68. Interaction of the C-terminal domain of the E. coli RNA polymerase α subunit with the UP element: recognizing the backbone structure in the minor groove surface11Edited by R. Ebright

    Article • Journal of Molecular Biology, February 2001, Elsevier

    Professor Yoshiyuki Tanaka

  69. Well-Conserved Tandem G·A Pairs and the Flanking C·G Pair in Hammerhead Ribozymes Are Sufficient for Capture of Structurally and Catalytically Important Metal Ions

    Article • Journal of the American Chemical Society, November 2000, American Chemical Society (ACS)

    Professor Yoshiyuki Tanaka

  70. Significant activity of a modified ribozyme with N7-deazaguanine at G10.1: the double-metal-ion mechanism of catalysis in reactions catalysed by hammerhead ribozymes

    Article • Genes to Cells, August 2000, Wiley

    Professor Yoshiyuki Tanaka

  71. Solution Structure of an RNA Duplex Including a C−U Base Pair † , ‡

    Article • Biochemistry, June 2000, American Chemical Society (ACS)

    Dr Chojiro Kojima, Professor Yoshiyuki Tanaka

  72. Significant change in the structure of a ribozyme upon introduction of a phosphorothioate linkage at P9: NMR reveals a conformational fluctuation in the core region of a hammerhead ribozyme

    Article • FEBS Letters, May 2000, Wiley

    Professor Yoshiyuki Tanaka

  73. Chemical and enzymatic probing of effector-mediated changes in the conformation of a maxizyme

    Article • Journal of Inorganic Biochemistry, March 2000, Elsevier

    Professor Yoshiyuki Tanaka

  74. Design of a Novel Allosteric Ribozyme "Maxizyme" with a Sensor Function.

    Article • Seibutsu Butsuri, January 2000, Biophysical Society of Japan

    Professor Yoshiyuki Tanaka

  75. Translational induction of heat shock transcription factor sigma 32: evidence for a built-in RNA thermosensor

    Article • Genes & Development, March 1999, Cold Spring Harbor Laboratory Press

    Professor Yoshiyuki Tanaka

  76. A'-form RNA double helix in the single crystal structure of r(UGAGCUUCGGCUC)

    Article • Nucleic Acids Research, February 1999, Oxford University Press (OUP)

    Professor Yoshiyuki Tanaka

  77. Spectroscopic determination of thermodynamic parameters in partial melting process of RNA

    Article • January 1999, Springer Science + Business Media

    Professor Yoshiyuki Tanaka

  78. RNA Conformational Polymorphism: A'-RNA Conformation in the Crystal Structure of r(UGAGCUUCGGCUC)

    Article • February 1998, Protein Data Bank, Rutgers University

    Professor Yoshiyuki Tanaka

  79. Structural Studies on the MercuryII-Mediated T-T Base-Pair Using NMR Spectroscopy

    Article • Wiley

    Professor Yoshiyuki Tanaka