All Stories

  1. Toward Chemoselective Modification of Selenocysteine-Containing Biomolecules Via Doubly Activated Cyclopropanes
  2. Identification of a novel small-molecule compound that suppresses depolarization-induced CYP11B2 expression and aldosterone production in KCNJ5 mutant adrenocortical cells
  3. Hepatic Selenoprotein P Impairs Bone Formation via Osteoblastic IGF-1 Resistance
  4. Novel antioxidant effects of deuterated polyunsaturated fatty acids against lipid peroxidation in cell membranes: hypothesis paper
  5. Selenium metabolism, lipid peroxidation, and ferroptosis sensitivity: Lessons from selenium deficiency
  6. NRF2-dependent suppression of selenoprotein P expression promotes intracellular selenium metabolic remodeling and upregulation of antioxidant selenoproteins in hepatocellular carcinoma
  7. Lactoferrin attenuates renal fibrosis and uremic sarcopenia in a mouse model of adenine-induced chronic kidney disease
  8. Modifications of DJ-1 in which pI shifts to acidic in red blood cells a potential biomarker for Parkinson’s disease at early stages
  9. Differential associations between selenoprotein P and distal sensorimotor polyneuropathy in people with and without diabetes: KORA F4/FF4 study
  10. Endocytic vesicles act as vehicles for glucose uptake in response to growth factor stimulation
  11. Cholesterol is more readily oxidized than phospholipid linoleates in cell membranes to produce cholesterol hydroperoxides
  12. Sulforaphane decreases serum selenoprotein P levels through enhancement of lysosomal degradation independent of Nrf2
  13. Antioxidant action of persulfides and polysulfides against free radical-mediated lipid peroxidation
  14. Essential trace element selenium and redox regulation: its metabolism, physiological function, and related diseases
  15. Selenoprotein P Concentrations in the Cerebrospinal Fluid and Serum of Individuals Affected by Amyotrophic Lateral Sclerosis, Mild Cognitive Impairment and Alzheimer’s Dementia
  16. Redox-sensitive DJ-1 protein: an insight into physiological roles, secretion, and therapeutic target
  17. Safety of selenium exposure and limitations of selenoprotein maximization: Molecular and epidemiologic perspectives
  18. Nephronectin influences EAE development by regulating the Th17/Treg balance via reactive oxygen species
  19. Role of selenoprotein P expression in the function of pancreatic β cells: Prevention of ferroptosis-like cell death and stress-induced nascent granule degradation
  20. Diverse cytoprotective actions of vitamin E isoforms- role as peroxyl radical scavengers and complementary functions with selenoproteins
  21. Selenium Transport Mechanism via Selenoprotein P—Its Physiological Role and Related Diseases
  22. Methylmercury induces neuronal cell death by inducing TNF-α expression through the ASK1/p38 signaling pathway in microglia
  23. Lipid peroxidation products as a mediator of toxicity and adaptive response – The regulatory role of selenoprotein and vitamin E
  24. Identification of an endogenous long non-coding RNA that inhibits selenoprotein P translation- New regulatory mechanism of SeP translation
  25. Selenoprotein P-mediated reductive stress impairs cold-induced thermogenesis in brown fat
  26. Hydrogen Peroxide Causes Cell Death via Increased Transcription of HOXB13 in Human Lung Epithelial A549 Cells
  27. The Association Between Concurrence of Infection and the Onset of Severe Eruption or Liver Injury in Patients Using Antipyretic Analgesics: A Matched, Nested Case‐Control Study
  28. Selenoprotein P; P for Plasma, Prognosis, Prophylaxis, and More
  29. DJ-1-binding compound B enhances Nrf2 activity through the PI3-kinase-Akt pathway by DJ-1-dependent inactivation of PTEN
  30. Selenoprotein P as an <i>in vivo</i> redox regulator: disorders related to its deficiency and excess
  31. Diagnostic and Prognostic Significance of Serum Levels of SeP (Selenoprotein P) in Patients With Pulmonary Hypertension
  32. Selenoprotein P as a significant regulator of pancreatic β cell function
  33. Polymerization of Oxidized DJ-1 via Noncovalent and Covalent Binding: Significance of Disulfide Bond Formation
  34. Response by Kikuchi et al Regarding Article, “Selenoprotein P Promotes the Development of Pulmonary Arterial Hypertension: A Possible Novel Therapeutic Target”
  35. Serum selenoprotein P, but not selenium, predicts future hyperglycemia in a general Japanese population
  36. Tocopherol suppresses 24(S)-hydroxycholesterol-induced cell death via inhibition of CaMKII phosphorylation
  37. 6-Hydroxydopamine induces secretion of PARK7/DJ-1 via autophagy-based unconventional secretory pathway
  38. Distribution of oxidized DJ-1 in Parkinson’s disease-related sites in the brain and in the peripheral tissues: effects of aging and a neurotoxin
  39. PARK7 modulates autophagic proteolysis through binding to the N-terminally arginylated form of the molecular chaperone HSPA5
  40. Diagnosis of Parkinson’s disease and the level of oxidized DJ-1 protein
  41. Pleckstrin homology domain of p210 BCR-ABL interacts with cardiolipin to regulate its mitochondrial translocation and subsequent mitophagy
  42. Selenoprotein P-neutralizing antibodies improve insulin secretion and glucose sensitivity in type 2 diabetes mouse models
  43. Eicosapentaenoic acid down-regulates expression of the selenoprotein P gene by inhibiting SREBP-1c protein independently of the AMP-activated protein kinase pathway in H4IIEC3 hepatocytes
  44. Effect of vitamin E on 24( S )-hydroxycholesterol-induced necroptosis-like cell death and apoptosis
  45. Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle
  46. Interleukin-27 Enhances the Potential of Reactive Oxygen Species Generation from Monocyte-derived Macrophages and Dendritic cells by Induction of p47phox
  47. DJ-1 as a Biomarker of Parkinson’s Disease
  48. Oxidized Lipoprotein as a Major Vessel Cell Proliferator in Oxidized Human Serum
  49. Oxidation and interaction of DJ-1 with 20S proteasome in the erythrocytes of early stage Parkinson’s disease patients
  50. The protective role of DJ-1 in ultraviolet-induced damage of human skin: DJ-1 levels in the stratum corneum as an indicator of antioxidative defense
  51. New aspects of 24(S)-hydroxycholesterol in modulating neuronal cell death
  52. Enhancement of lipid peroxidation and its amelioration by vitamin E in a subject with mutations in theSBP2gene
  53. 24(S)-Hydroxycholesterol induces RIPK1-dependent but MLKL-independent cell death in the absence of caspase-8
  54. Development of a Sol Particle Homogeneous Immunoassay for Measuring Full‐Length Selenoprotein P in Human Serum
  55. Selenoprotein P as a diabetes-associated hepatokine that impairs angiogenesis by inducing VEGF resistance in vascular endothelial cells
  56. Immunostaining of Oxidized DJ-1 in Human and Mouse Brains
  57. 7-Hydroxycholestrol as a possible biomarker of cellular lipid peroxidation: Difference between cellular and plasma lipid peroxidation
  58. Diverse functions of 24(S)-hydroxycholesterol in the brain
  59. LECT2 Functions as a Hepatokine That Links Obesity to Skeletal Muscle Insulin Resistance
  60. Adaptive responses induced by 24S-hydroxycholesterol through liver X receptor pathway reduce 7-ketocholesterol-caused neuronal cell death
  61. Induction of apoptosis and necroptosis by 24(S)-hydroxycholesterol is dependent on activity of acyl-CoA:cholesterol acyltransferase 1
  62. Oxidized DJ-1 as a possible biomarker of Parkinson’s disease
  63. Metformin Suppresses Expression of the Selenoprotein P Gene via an AMP-activated Kinase (AMPK)/FoxO3a Pathway in H4IIEC3 Hepatocytes
  64. Serum selenium and selenoprotein P in patients with silicosis
  65. Oxidized DJ-1 Inhibits p53 by Sequestering p53 from Promoters in a DNA-Binding Affinity-Dependent Manner
  66. Enhanced CD36 expression changes the role of Nrf2 activation from anti-atherogenic to pro-atherogenic in apoE-deficient mice
  67. Cytoprotective effects of geraniin against peroxynitrite- and peroxyl radical-induced cell death via free radical scavenging activity
  68. Novel compound heterozygous mutations in the SBP2 gene: characteristic clinical manifestations and the implications of GH and triiodothyronine in longitudinal bone growth and maturation
  69. Inverse Correlation between Serum Levels of Selenoprotein P and Adiponectin in Patients with Type 2 Diabetes
  70. Novel compound heterozygous mutations in the SBP2 gene: characteristic clinical manifestations and the implications of GH and triiodothyronine in longitudinal bone growth and maturation
  71. A novel fluorescent probe with high sensitivity and selective detection of lipid hydroperoxides in cells
  72. Oxidation of DJ-1 Induced by 6-Hydroxydopamine Decreasing Intracellular Glutathione
  73. α-Tocopheryl phosphate: Uptake, hydrolysis, and antioxidant action in cultured cells and mouse
  74. 24(S)-Hydroxycholesterol Induces Neuronal Cell Death through Necroptosis, a Form of Programmed Necrosis
  75. Central nervous system-specific deletion of transcription factor Nrf1 causes progressive motor neuronal dysfunction
  76. Selenoprotein P
  77. Selenoprotein-P is down-regulated in prostate cancer, which results in lack of protection against oxidative damage
  78. Phosphorylation of p66shc mediates 6-hydroxydopamine cytotoxicity
  79. A Liver-Derived Secretory Protein, Selenoprotein P, Causes Insulin Resistance
  80. Cytoprotective effects of vitamin E homologues against glutamate-induced cell death in immature primary cortical neuron cultures: Tocopherols and tocotrienols exert similar effects by antioxidant function
  81. Elevation of oxidized DJ-1 in the brain and erythrocytes of Parkinson disease model animals
  82. Action of 6-amino-3-pyridinols as novel antioxidants against free radicals and oxidative stress in solution, plasma, and cultured cells
  83. Hydroxyoctadecadienoic acid as a potential biomarker for oxidative stress in patients with chronic hepatitis C
  84. Proteomic characterization of the striatum and midbrain treated with 6-hydroxydopamine: Alteration of 58-kDa glucose-regulated protein and C/EBP homologous protein
  85. The role of α-tocopherol in motor hypofunction with aging in α-tocopherol transfer protein knockout mice as assessed by oxidative stress biomarkers
  86. Preparation and application of monoclonal antibodies against oxidized DJ-1. Significant elevation of oxidized DJ-1 in erythrocytes of early-stage Parkinson disease patients
  87. Antioxidant action of sugar-pendant C60 fullerenes
  88. Assessment of the antioxidant capacity of a fermented grain food product, Antioxidant Biofactor (AOB), by using pyranine and pyrogallol red as a combined probe
  89. Characterization of cellular uptake and distribution of coenzyme Q10 and vitamin E in PC12 cells☆
  90. Protein Adsorption of Ultrafine Metal Oxide and Its Influence on Cytotoxicity toward Cultured Cells
  91. Sustainable and practical degradation of intact chicken feathers by cultivating a newly isolated thermophilic Meiothermus ruber H328
  92. Hydroxyoctadecadienoic acid and oxidatively modified peroxiredoxins in the blood of Alzheimer's disease patients and their potential as biomarkers
  93. A Gene Expression Profiling Approach to Study the Influence of Ultrafine Particles on Rat Lungs
  94. Characterization of novel furan compounds on the basis of their radical scavenging activity and cytoprotective effects against glutamate- and lipopolysaccharide-induced insults
  95. Induction of adaptive response and enhancement of PC12 cell tolerance by lipopolysaccharide primarily through the upregulation of glutathione S-transferase A3 via Nrf2 activation
  96. Assessment of Radical Scavenging Capacity and Lipid Peroxidation Inhibiting Capacity of Antioxidant
  97. Effect of Oxygen Concentration on Free Radical-Induced Cytotoxicity
  98. Simple Assessment of Radical Scavenging Capacity of Beverages
  99. Antioxidant capacity of BO-653, 2,3-dihydro-5-hydroxy-4,6-di-tert-butyl-2,2-dipentylbenzofuran, and uric acid as evaluated by ORAC method and inhibition of lipid peroxidation
  100. Regulation of GCL activity and cellular glutathione through inhibition of ERK phosphorylation
  101. γ-Tocopheryl quinone, notα-tocopheryl quinone, induces adaptive response through up-regulation of cellular glutathione and cysteine availability via activation of ATF4
  102. Chemical Reactivities and Physical Effects in Comparison between Tocopherols and Tocotrienols: Physiological Significance and Prospects as Antioxidants
  103. Cholesterol is more susceptible to oxidation than linoleates in cultured cells under oxidative stress induced by selenium deficiency and free radicals
  104. Protective effects of 15-deoxy-Δ12,14 -prostaglandin J2 against glutamate-induced cell death in primary cortical neuron cultures: induction of adaptive response and enhancement of cell tolerance primarily through up-regulation of cellular glutathione
  105. Levels of Lipid Peroxidation in Human Plasma and Erythrocytes: Comparison between Fatty Acids and Cholesterol
  106. Molecular mechanisms of 6-hydroxydopamine-induced cytotoxicity in PC12 cells: Involvement of hydrogen peroxide-dependent and -independent action
  107. Cytotoxic effects of various stressors on PC12 cells: Involvement of oxidative stress and effect of antioxidants
  108. Induction of Adaptive Response and Enhancement of PC12 Cell Tolerance by 7-Hydroxycholesterol and 15-Deoxy-Δ12,14-Prostaglandin J2through Up-regulation of Cellular Glutathione via Different Mechanisms
  109. Turning point in apoptosis/necrosis induced by hydrogen peroxide
  110. Adaptive response induced by lipid peroxidation products in cell cultures
  111. Lipid peroxidation: Mechanisms, inhibition, and biological effects
  112. 4-Hydroxynonenal Induces Adaptive Response and Enhances PC12 Cell Tolerance Primarily through Induction of Thioredoxin Reductase 1 via Activation of Nrf2
  113. Adaptation to hydrogen peroxide enhances PC12 cell tolerance against oxidative damage
  114. Cytotoxic effect of formaldehyde with free radicals via increment of cellular reactive oxygen species
  115. Characterization of monochloramine toxicity on PC12 cells and protective effect of tocopherol via antioxidative function
  116. Proteomic characterization of oxidative dysfunction in human umbilical vein endothelial cells (HUVEC) induced by exposure to oxidized LDL
  117. Characterization of Cellular Uptake and Distribution of Vitamin E
  118. Domain structure of bi-functional selenoprotein P
  119. Application of Water-Soluble Radical Initiator, 2,2′-Azobis-[2-(2-imidazolin-2-yl)propane] Dihydrochloride, to a Study of Oxidative Stress
  120. DJ-1 has a role in antioxidative stress to prevent cell death
  121. DJ-1 has a role in antioxidative stress to prevent cell death
  122. Effects of a Novel Gaseous Antioxidative System Containing a Rosemary Extract on the Oxidation Induced by Nitrogen Dioxide and Ultraviolet Radiation
  123. Selenoprotein P, as a predictor for evaluating gemcitabine resistance in human pancreatic cancer cells
  124. Cell Death Caused by Selenium Deficiency and Protective Effect of Antioxidants
  125. Characterization of selenoprotein P as a selenium supply protein
  126. A Comparative Study on the Hydroperoxide and Thiol Specificity of the Glutathione Peroxidase Family and Selenoprotein P
  127. Production and Application of Monoclonal Antibodies to Human Selenoprotein P.
  128. Selenoprotein P. Its Structure and Functions.
  129. Selenoprotein P in Human Plasma as an Extracellular Phospholipid Hydroperoxide Glutathione Peroxidase