All Stories

  1. Turning aging cells into a live vaccine: engineered senescent cancer cells with adjuvant celecoxib for immunotherapy

    Article • December 2025, openRxiv

    Professor Yongzhuo Huang

  2. Phospholipid complex-based microemulsion for treating concurrence of primary sclerosing cholangitis and inflammatory bowel disease via gut-liver crosstalk

    Article • Chinese Chemical Letters, October 2025, Elsevier

    Professor Yongzhuo Huang

  3. Inhalable Inclusion Cocrystal of Exocarpium Citri Grandis Volatile Oil for Treatment of Acute Lung Injury

    Article • AAPS PharmSciTech, September 2025, Springer Science + Business Media

    Professor Yongzhuo Huang

  4. Biomimetically engineered plant-derived exosomes-like nanovesicles for rheumatoid arthritis therapy

    Article • Chinese Chemical Letters, September 2025, Elsevier

    Professor Yongzhuo Huang

  5. Ascorbic Acid-Derived Supramolecular Gels Induce Immunogenic Ferroptosis in Cancer Cells to Potentiate Tumor Immunotherapy

    Article • ACS Nano, September 2025, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  6. Drug Repurposing with Topical Paclitaxel Delivery for Psoriasis Treatment Enabled by Plant-Inspired Molecular Assembly

    Article • ACS Applied Materials & Interfaces, August 2025, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  7. Ion-Gradient Driven Drug-Loading Liposomes for Codelivery of Shikonin/Regorafenib for Cancer Immunometabolic Therapy and Postoperative Intervention

    Article • ACS Applied Materials & Interfaces, July 2025, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  8. Nanohydroxyapatite-Stabilized Pickering-Emulsion-Incorporated Hydrogel Prevents Postoperative Osteosarcoma Recurrence and Promotes Bone Repair

    Article • Nano Letters, June 2025, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  9. A bigel co-delivering highly hydrophilic and hydrophobic natural compounds for enhanced ulcerative colitis therapy

    Article • International Journal of Pharmaceutics, June 2025, Elsevier

    Professor Yongzhuo Huang

  10. Microalgae-carrying nanomedicine for bioadhesive drug delivery for treating chemotherapy-induced intestinal injury

    Article • Asian Journal of Pharmaceutical Sciences, April 2025, Elsevier

    Professor Yongzhuo Huang

  11. Targeting stem-property and vasculogenic mimicry for sensitizing paclitaxel therapy of triple-negative breast cancer by biomimetic codelivery

    Article • Acta Pharmaceutica Sinica B, April 2025, Elsevier

    Professor Yongzhuo Huang

  12. In-situ trichosanthin-IL2/pectin dynamic hydrogel activates dendritic cells and reverses T cell exhaustion for post-operative cancer therapy

    Article • Chemical Engineering Journal, February 2025, Elsevier

    Professor Yongzhuo Huang

  13. An enhanced bioactive chitosan-modified microemulsion for mucosal healing of ulcerative colitis

    Article • International Journal of Biological Macromolecules, January 2025, Elsevier

    Professor Yongzhuo Huang

  14. Natural product-integrated microneedle patch for rheumatoid arthritis treatment through anti-inflammation and angiogenesis suppression

    Article • Biomaterials Science, January 2025, Royal Society of Chemistry

    Professor Yongzhuo Huang

  15. Co-delivery of TRAIL DNA and salinomycin for cancer therapy via enhanced apoptosis and cancer stemness inhibition

    Article • Journal of Materials Chemistry B, January 2025, Royal Society of Chemistry

    Professor Yongzhuo Huang

  16. Cellular vesicles-based “all-in-one” vaccine platform triggers mucosal immunity against respiratory viruses

    Article • Nano Today, December 2024, Elsevier

    Professor Yongzhuo Huang

  17. Intratumoral lactic acid neutralization strategy for boosting chemoimmunotherapy using liposomal sodium bicarbonate

    Article • Science Bulletin, December 2024, Elsevier

    Professor Yongzhuo Huang

  18. Carrier Polymer-Free Dissolvable Microneedles Enable Superhigh Drug Payload for Percutaneous Protein Delivery

    Article • ACS Materials Letters, October 2024, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  19. Uncovering key mechanisms and intervention therapies in aging skin

    Article • Cytokine & Growth Factor Reviews, October 2024, Elsevier

    Professor Yongzhuo Huang

  20. Alginate/silk fibroin/Zn2+ composite microspheres for site-specific delivery for enhanced ulcerative colitis therapy

    Article • Chemical Engineering Journal, September 2024, Elsevier

    Professor Yongzhuo Huang

  21. Coronavirus spike protein-based vaccines. Vaccine delivery systems

    Article • Medicine in Drug Discovery, September 2024, Elsevier

    Dr. Akmal M. Asrorov, Professor Yongzhuo Huang

  22. Aggregation-caused quenching to crystallization-induced emission transformation: hydration-induced luminescence in crystal curcumin with tunable thermochromism for in vivo tracking

    Article • Science China Materials, August 2024, Springer Science + Business Media

    Professor Yongzhuo Huang

  23. Immunometabolic rewiring in macrophages for periodontitis treatment via nanoquercetin-mediated leverage of glycolysis and OXPHOS

    Article • Acta Pharmaceutica Sinica B, August 2024, Elsevier

    Professor Yongzhuo Huang

  24. Albumin is a reliable drug-delivering molecule: Highlighting points in cancer therapy

    Article • Medicine in Drug Discovery, June 2024, Elsevier

    Dr. Akmal M. Asrorov, Professor Yongzhuo Huang

  25. Interactions between nanoparticles and lymphatic systems: Mechanisms and applications in drug delivery

    Article • Advanced Drug Delivery Reviews, June 2024, Elsevier

    Professor Yongzhuo Huang

  26. A Spatially Stable Crystal-Particle Gel to Trap Patchouli Oil for Efficient Colonic Drug Delivery

    Article • ACS Applied Materials & Interfaces, May 2024, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  27. Gastroretentive Raft Forming System for Enhancing Therapeutic Effect of Drug‐Loaded Hollow Mesoporous Silica on Gastric Ulcers

    Article • Advanced Healthcare Materials, May 2024, Wiley

    Professor Yongzhuo Huang

  28. Naturally sourced amphiphilic peptides as paclitaxel vehicles for breast cancer treatment

    Article • Biomaterials Advances, May 2024, Elsevier

    Professor Yongzhuo Huang

  29. Biomimetic nano-chelate diethyldithiocarbamate Cu/Fe for enhanced metalloimmunity and ferroptosis activation in glioma therapy

    Article • Journal of Controlled Release, April 2024, Elsevier

    Professor Yongzhuo Huang

  30. Asiatic acid cyclodextrin inclusion micro-cocrystal for insoluble drug delivery and acute lung injury therapy enhancement

    Article • Journal of Nanobiotechnology, March 2024, Springer Science + Business Media

    Professor Yongzhuo Huang

  31. Heparin-Conjugated ACE2-Bearing Extracellular Vesicles As Engineered Dual-Decoy for Combating the SARS-CoV-2 Omicron Variant via Pulmonary Delivery

    Article • ACS Materials Letters, March 2024, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  32. Blocking tumor-platelet crosstalk to prevent tumor metastasis via reprograming glycolysis using biomimetic membrane-hybridized liposomes

    Article • Journal of Controlled Release, February 2024, Elsevier

    Professor Yongzhuo Huang

  33. Environment-responsive dendrobium polysaccharide hydrogel embedding manganese microsphere as a post-operative adjuvant to boost cascaded immune cycle against melanoma

    Article • Theranostics, January 2024, Ivyspring International Publisher

    Professor Yongzhuo Huang

  34. Tumor-Associated Macrophage Targeting of Nanomedicines in Cancer Therapy

    Article • Pharmaceutics, December 2023, MDPI AG

    Professor Yongzhuo Huang

  35. Epigenetic-based combination therapy and liposomal codelivery overcomes osimertinib-resistant NSCLC via repolarizing tumor-associated macrophages

    Article • Acta Pharmacologica Sinica, December 2023, Springer Science + Business Media

    Professor Yongzhuo Huang

  36. Rational design of oral delivery nanosystems for hypoglycemic peptides

    Article • Nano Today, December 2023, Elsevier

    Professor Yongzhuo Huang

  37. Pathologically catalyzed physical coating restores the intestinal barrier for inflammatory bowel disease therapy

    Article • Journal of Nanobiotechnology, November 2023, Springer Science + Business Media

    Professor Yongzhuo Huang

  38. Author correction to “Neutralization of SARS-CoV-2 pseudovirus using ACE2-engineered extracellular vesicles” [Acta Pharmaceutica Sinica B 12 (2022) 1523–1533]

    Article • Acta Pharmaceutica Sinica B, November 2023, Elsevier

    Professor Yongzhuo Huang

  39. Liposomal Resveratrol Alleviates Platelet Storage Lesion via Antioxidation and the Physical Buffering Effect

    Article • ACS Applied Materials & Interfaces, September 2023, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  40. Mitigation of Anti‐Drug Antibody Production for Augmenting Anticancer Efficacy of Therapeutic Protein via Co‐Injection of Nano‐Rapamycin

    Article • Small, September 2023, Wiley

    Professor Yongzhuo Huang

  41. Oral pectin/oligochitosan microspheres for colon-specific controlled release of quercetin to treat inflammatory bowel disease

    Article • Carbohydrate Polymers, September 2023, Elsevier

    Professor Yongzhuo Huang

  42. Correction to “Lactoferrin-Modified Gambogic Acid Liposomes for Colorectal Cancer Treatment”

    Article • Molecular Pharmaceutics, August 2023, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  43. Cyclodextrin-Coordinated Liposome-in-Gel for Transcutaneous Quercetin Delivery for Psoriasis Treatment

    Article • ACS Applied Materials & Interfaces, August 2023, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  44. Lactoferrin-Modified Gambogic Acid Liposomes for Colorectal Cancer Treatment

    Article • Molecular Pharmaceutics, July 2023, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  45. Targeting lactate metabolism and immune interaction in breast tumor via protease-triggered delivery

    Article • Journal of Controlled Release, June 2023, Elsevier

    Professor Yongzhuo Huang

  46. Carbohydrate Strengthens the Immunotherapeutic Effect of Small-Molecule PD-L1 Inhibitors

    Article • Journal of Medicinal Chemistry, May 2023, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  47. Cell penetrating peptides: Highlighting points in cancer therapy

    Article • Drug Development Research, May 2023, Wiley

    Dr. Akmal M. Asrorov, Professor Yongzhuo Huang

  48. Regulating lactate-related immunometabolism and EMT reversal for colorectal cancer liver metastases using shikonin targeted delivery

    Article • Journal of Experimental & Clinical Cancer Research, May 2023, Springer Science + Business Media

    Professor Yongzhuo Huang

  49. Toad venom bufadienolides and bufotoxins: An updated review

    Article • Drug Development Research, May 2023, Wiley

    Dr. Akmal M. Asrorov, Professor Yongzhuo Huang

  50. Living Cells and Cell-Derived Vesicles: A Trojan Horse Technique for Brain Delivery

    Article • Pharmaceutics, April 2023, MDPI AG

    Professor Yongzhuo Huang

  51. Topical Delivery of Cell-Penetrating Peptide-Modified Human Growth Hormone for Enhanced Wound Healing

    Article • Pharmaceuticals, March 2023, MDPI AG

    Professor Yongzhuo Huang

  52. Pharmaceutical liposomal delivery—specific considerations of innovation and challenges

    Article • Biomaterials Science, January 2023, Royal Society of Chemistry

    Professor Yongzhuo Huang

  53. Recombinant cell-penetrating trichosanthin synergizes anti-PD-1 therapy in colorectal tumor

    Article • International Journal of Biological Sciences, January 2023, Ivyspring International Publisher

    Professor Yongzhuo Huang

  54. Targeting glycolysis for cancer therapy using drug delivery systems

    Article • Journal of Controlled Release, January 2023, Elsevier

    Professor Yongzhuo Huang

  55. Mannosylated engineered trichosanthin-legumain protein vaccine hydrogel for breast cancer immunotherapy

    Article • International Journal of Biological Macromolecules, December 2022, Elsevier

    Dr. Akmal M. Asrorov, Professor Yongzhuo Huang

  56. Intracellular delivery of messenger RNA to macrophages with surfactant-derived lipid nanoparticles

    Article • Materials Today Advances, December 2022, Elsevier

    Professor Yongzhuo Huang

  57. Localized delivery of nanomedicine and antibodies for combating COVID-19

    Article • Acta Pharmaceutica Sinica B, September 2022, Elsevier

    Professor Yongzhuo Huang

  58. “Two-birds-one-stone” colon-targeted nanomedicine treats ulcerative colitis via remodeling immune microenvironment and anti-fibrosis

    Article • Journal of Nanobiotechnology, August 2022, Springer Science + Business Media

    Professor Yongzhuo Huang

  59. Gold Nanocage-Based Photothermal Ablation Facilitates In Situ Vaccination for Melanoma Therapy

    Article • ACS Applied Materials & Interfaces, August 2022, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  60. Evaluation of Transdermal Transport and Concurrent Cutaneous Hydrolysis of Timolol Prodrug for the Treatment of Infantile Hemangiomas

    Article • Pharmaceutics, August 2022, MDPI AG

    Professor Yongzhuo Huang

  61. Nanoplateletsomes restrain metastatic tumor formation through decoy and active targeting in a preclinical mouse model

    Article • Acta Pharmaceutica Sinica B, August 2022, Elsevier

    Professor Yongzhuo Huang

  62. Advances on Delivery of Cytotoxic Enzymes as Anticancer Agents

    Article • Molecules, June 2022, MDPI AG

    Dr. Akmal M. Asrorov, Professor Yongzhuo Huang

  63. Anti-alcoholism drug disulfiram for targeting glioma energy metabolism using BBB-penetrating delivery of fixed-dose combination

    Article • Nano Today, June 2022, Elsevier

    Professor Yongzhuo Huang

  64. Brain-targeting biomimetic nanoparticles for codelivery of celastrol and LY2157299 for reversing glioma immunosuppression

    Article • International Journal of Pharmaceutics, May 2022, Elsevier

    Professor Yongzhuo Huang

  65. Lipid Metabolism Regulation Based on Nanotechnology for Enhancement of Tumor Immunity

    Article • Frontiers in Pharmacology, March 2022, Frontiers

    Professor Yongzhuo Huang

  66. A drug-free nanozyme for mitigating oxidative stress and inflammatory bowel disease

    Article • Journal of Nanobiotechnology, March 2022, Springer Science + Business Media

    Professor Yongzhuo Huang

  67. Inhaled heparin polysaccharide nanodecoy against SARS-CoV-2 and variants

    Article • Acta Pharmaceutica Sinica B, February 2022, Elsevier

    Professor Yongzhuo Huang

  68. Nanotherapeutic macrophage-based immunotherapy for the peritoneal carcinomatosis of lung cancer

    Article • Nanoscale, January 2022, Royal Society of Chemistry

    Dr. Akmal M. Asrorov, Professor Yongzhuo Huang

  69. In Situ Pathologically Catalyzed Polydopamine Coating Enhances the Intestinal Barrier for Inflammatory Bowel Disease Therapy

    Article • SSRN Electronic Journal, January 2022, Elsevier

    Professor Yongzhuo Huang

  70. Remodeling immune microenvironment in periodontitis using resveratrol liposomes as an antibiotic-free therapeutic strategy

    Article • Journal of Nanobiotechnology, December 2021, Springer Science + Business Media

    Professor Yongzhuo Huang

  71. Recombinant cancer nanovaccine for targeting tumor-associated macrophage and remodeling tumor microenvironment

    Article • Nano Today, October 2021, Elsevier

    Professor Yongzhuo Huang

  72. Disulfiram-loaded lactoferrin nanoparticles for treating inflammatory diseases

    Article • Acta Pharmacologica Sinica, September 2021, Springer Science + Business Media

    Professor Yongzhuo Huang

  73. Neutralization of SARS-CoV-2 pseudovirus using ACE2-engineered extracellular vesicles

    Article • Acta Pharmaceutica Sinica B, September 2021, Elsevier

    Professor Yongzhuo Huang

  74. Remodeling “cold” tumor immune microenvironment via epigenetic-based therapy using targeted liposomes with in situ formed albumin corona

    Article • Acta Pharmaceutica Sinica B, September 2021, Elsevier

    Professor Yongzhuo Huang, Dr. Akmal M. Asrorov

  75. Genetically-engineered “all-in-one” vaccine platform for cancer immunotherapy

    Article • Acta Pharmaceutica Sinica B, June 2021, Elsevier

    Professor Yongzhuo Huang

  76. Teaching new tricks to old dogs: A review of drug repositioning of disulfiram for cancer nanomedicine

    Article • View, February 2021, Wiley

    Professor Yongzhuo Huang

  77. Biomimetic camouflage delivery strategies for cancer therapy

    Article • Nanoscale, January 2021, Royal Society of Chemistry

    Dr. Akmal M. Asrorov, Professor Yongzhuo Huang

  78. Magnetism-mediated targeting hyperthermia-immunotherapy in “cold” tumor with CSF1R inhibitor

    Article • Theranostics, January 2021, Ivyspring International Publisher

    Professor Yongzhuo Huang, Dr. Akmal M. Asrorov

  79. Biomimetic codelivery overcomes osimertinib-resistant NSCLC and brain metastasis via macrophage-mediated innate immunity

    Article • Journal of Controlled Release, January 2021, Elsevier

    Professor Yongzhuo Huang

  80. Anti-PD-L1 mediating tumor-targeted codelivery of liposomal irinotecan/JQ1 for chemo-immunotherapy

    Article • Acta Pharmacologica Sinica, December 2020, Springer Science + Business Media

    Professor Yongzhuo Huang

  81. Metabolic modulation via mTOR pathway and anti-angiogenesis remodels tumor microenvironment using PD-L1-targeting codelivery

    Article • Biomaterials, October 2020, Elsevier

    Professor Yongzhuo Huang

  82. Lactoferrin-mediated macrophage targeting delivery and patchouli alcohol-based therapeutic strategy for inflammatory bowel diseases

    Article • Acta Pharmaceutica Sinica B, October 2020, Elsevier

    Professor Yongzhuo Huang

  83. Remodeling tumor immune microenvironment (TIME) for glioma therapy using multi-targeting liposomal codelivery

    Article • Journal for ImmunoTherapy of Cancer, August 2020, BMJ

    Professor Yongzhuo Huang

  84. Publisher Correction: ‘TRAIL-based gene delivery and therapeutic strategies’ and ‘Overview of recent advances in liposomal nanoparticle-based cancer immunotherapy’

    Article • Acta Pharmacologica Sinica, July 2020, Springer Science + Business Media

    Professor Yongzhuo Huang

  85. Nanotechnology-Based Histone Deacetylase Inhibitors for Cancer Therapy

    Article • Frontiers in Cell and Developmental Biology, June 2020, Frontiers

    Professor Yongzhuo Huang

  86. Dual‐Targeting to Cancer Cells and M2 Macrophages via Biomimetic Delivery of Mannosylated Albumin Nanoparticles for Drug‐Resistant Cancer Therapy

    Article • Advanced Functional Materials, April 2020, Wiley

    Professor Yongzhuo Huang

  87. Biomimetic metal-organic nanoparticles prepared with a 3D-printed microfluidic device as a novel formulation for disulfiram-based therapy against breast cancer

    Article • Applied Materials Today, March 2020, Elsevier

    Teng Zhou, Professor Yongzhuo Huang

  88. A Trojan horse biomimetic delivery strategy using mesenchymal stem cells for PDT/PTT therapy against lung melanoma metastasis

    Article • Biomaterials Science, January 2020, Royal Society of Chemistry

    Professor Yongzhuo Huang

  89. Macrophage-based nanotherapeutic strategies in ulcerative colitis

    Article • Journal of Controlled Release, January 2020, Elsevier

    Professor Yongzhuo Huang

  90. Deformable liposomal codelivery of vorinostat and simvastatin promotes antitumor responses through remodeling tumor microenvironment

    Article • Biomaterials Science, January 2020, Royal Society of Chemistry

    Dr. Akmal M. Asrorov, Professor Yongzhuo Huang

  91. BBB-penetrating codelivery liposomes treat brain metastasis of non-small cell lung cancer with EGFRT790M mutation

    Article • Theranostics, January 2020, Ivyspring International Publisher

    Professor Yongzhuo Huang

  92. Correction: A Trojan horse biomimetic delivery strategy using mesenchymal stem cells for PDT/PTT therapy against lung melanoma metastasis

    Article • Biomaterials Science, January 2020, Royal Society of Chemistry

    Professor Yongzhuo Huang

  93. Introduction to biomimetic therapeutics

    Article • Biomaterials Science, January 2020, Royal Society of Chemistry

    Professor Yongzhuo Huang

  94. Correction to Co-Delivery of Trichosanthin and Albendazole by Nano-Self-Assembly for Overcoming Tumor Multidrug-Resistance and Metastasis

    Article • ACS Applied Materials & Interfaces, December 2019, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  95. Advances on Tumor-Targeting Delivery of Cytotoxic Proteins

    Article • ACS Pharmacology & Translational Science, December 2019, American Chemical Society (ACS)

    Professor Yongzhuo Huang, Dr. Akmal M. Asrorov

  96. Correction to Codelivery of Sorafenib and Curcumin by Directed Self-Assembled Nanoparticles Enhances Therapeutic Effect on Hepatocellular Carcinoma

    Article • Molecular Pharmaceutics, December 2019, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  97. Recent progress in drug delivery

    Article • Acta Pharmaceutica Sinica B, November 2019, Elsevier

    Professor Yongzhuo Huang

  98. TRAIL-based gene delivery and therapeutic strategies

    Article • Acta Pharmacologica Sinica, August 2019, Springer Science + Business Media

    Professor Yongzhuo Huang

  99. Menthol-modified BSA nanoparticles for glioma targeting therapy using an energy restriction strategy

    Article • NPG Asia Materials, July 2019, Springer Science + Business Media

    Professor Yongzhuo Huang

  100. Trained Macrophage Bioreactor for Penetrating Delivery of Fused Antitumor Protein

    Article • ACS Applied Materials & Interfaces, June 2019, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  101. Transcutaneous Delivery of DNA/mRNA for Cancer Therapeutic Vaccination

    Article • The Journal of Gene Medicine, April 2019, Wiley

    Professor Yongzhuo Huang

  102. Reprogramming Tumor Immune Microenvironment (TIME) and Metabolism via Biomimetic Targeting Codelivery of Shikonin/JQ1

    Article • Nano Letters, April 2019, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  103. Genetically-engineered protein prodrug-like nanoconjugates for tumor-targeting biomimetic delivery via a SHEATH strategy

    Article • Nanoscale, January 2019, Royal Society of Chemistry

    Professor Yongzhuo Huang

  104. Targeting lipid metabolism to overcome EMT-associated drug resistance via integrin β3/FAK pathway and tumor-associated macrophage repolarization using legumain-activatable delivery

    Article • Theranostics, January 2019, Ivyspring International Publisher

    Professor Yongzhuo Huang

  105. The intra-brain distribution of brain targeting delivery systems

    Article • January 2019, Elsevier

    Professor Yongzhuo Huang

  106. Nano-Structural Effects on Gene Transfection: Large, Botryoid-Shaped Nanoparticles Enhance DNA Delivery via Macropinocytosis and Effective Dissociation

    Article • Theranostics, January 2019, Ivyspring International Publisher

    Professor Yongzhuo Huang

  107. Disulfiram Copper Nanoparticles Prepared with a Stabilized Metal Ion Ligand Complex Method for Treating Drug-Resistant Prostate Cancers

    Article • ACS Applied Materials & Interfaces, November 2018, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  108. Remodeling Tumor-Associated Macrophages and Neovascularization Overcomes EGFRT790M -Associated Drug Resistance by PD-L1 Nanobody-Mediated Codelivery

    Article • Small, October 2018, Wiley

    Professor Yongzhuo Huang

  109. The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis

    Article • Immunity, October 2018, Elsevier

    Professor Yongzhuo Huang

  110. Natural Brain Penetration Enhancer-Modified Albumin Nanoparticles for Glioma Targeting Delivery

    Article • ACS Applied Materials & Interfaces, September 2018, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  111. Tat-functionalized Ag-Fe 3 O 4 nano-composites as tissue-penetrating vehicles for tumor magnetic targeting and drug delivery

    Article • Acta Pharmaceutica Sinica B, August 2018, Elsevier

    Professor Yongzhuo Huang

  112. Antiglioma via regulating oxidative stress and remodeling tumor-associated macrophage using lactoferrin-mediated biomimetic codelivery of simvastatin/fenretinide

    Article • Journal of Controlled Release, August 2018, Elsevier

    Professor Yongzhuo Huang

  113. Roles of Albumin-Binding Proteins in Cancer Progression and Biomimetic Targeted Drug Delivery

    Article • ChemBioChem, July 2018, Wiley

    Professor Yongzhuo Huang

  114. A novel tumor-targeting treatment strategy uses energy restriction via co-delivery of albendazole and nanosilver

    Article • Nano Research, March 2018, Tsinghua University Press

    Professor Yongzhuo Huang

  115. Liposomal Codelivery of Doxorubicin and Andrographolide Inhibits Breast Cancer Growth and Metastasis

    Article • Molecular Pharmaceutics, March 2018, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  116. Targeting death receptors for drug-resistant cancer therapy: Codelivery of pTRAIL and monensin using dual-targeting and stimuli-responsive self-assembling nanocomposites

    Article • Biomaterials, March 2018, Elsevier

    Professor Yongzhuo Huang

  117. Macrophage-Membrane-Coated Nanoparticles for Tumor-Targeted Chemotherapy

    Article • Nano Letters, February 2018, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  118. Improved Protein Toxin Delivery Based on ATTEMPTS Systems

    Article • Current Drug Targets, February 2018, Bentham Science Publishers

    Professor Yongzhuo Huang

  119. Dual-targeting biomimetic delivery for anti-glioma activityviaremodeling the tumor microenvironment and directing macrophage-mediated immunotherapy

    Article • Chemical Science, January 2018, Royal Society of Chemistry

    Professor Yongzhuo Huang, xuejia kang

  120. Biomimetic albumin-modified gold nanorods for photothermo-chemotherapy and macrophage polarization modulation

    Article • Acta Pharmaceutica Sinica B, January 2018, Elsevier

    Professor Yongzhuo Huang

  121. Improved method for synthesis of low molecular weight protamine–siRNA conjugate

    Article • Acta Pharmaceutica Sinica B, January 2018, Elsevier

    Professor Yongzhuo Huang

  122. Smart Cell-Penetrating Peptide-Based Techniques for Intracellular Delivery of Therapeutic Macromolecules

    Article • January 2018, Elsevier

    Professor Yongzhuo Huang

  123. Reprogramming Tumor-Associated Macrophages To Reverse EGFRT790M Resistance by Dual-Targeting Codelivery of Gefitinib/Vorinostat

    Article • Nano Letters, November 2017, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  124. Cell-penetrating peptide-based non-invasive topical delivery systems

    Article • Journal of Pharmaceutical Investigation, November 2017, Springer Science + Business Media

    Professor Yongzhuo Huang

  125. Application of Monodisperse PEGs in Pharmaceutics: Monodisperse Polidocanols

    Article • Molecular Pharmaceutics, August 2017, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  126. Co-Delivery of Trichosanthin and Albendazole by Nano-Self-Assembly for Overcoming Tumor Multidrug-Resistance and Metastasis

    Article • ACS Applied Materials & Interfaces, August 2017, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  127. Two-birds-one-stone delivery and therapeutic strategy for overcoming chemtherapy resistance

    Article • Advanced Functional Materials, July 2017, Wiley

    Professor Yongzhuo Huang

  128. Cancer nanobiotechnolgy

    Article • Acta Pharmacologica Sinica, June 2017, Springer Science + Business Media

    Professor Yongzhuo Huang

  129. Microneedle-Assisted, DC-Targeted Codelivery of pTRP-2 and Adjuvant of Paclitaxel for Transcutaneous Immunotherapy

    Article • Small, May 2017, Wiley

    Professor Yongzhuo Huang

  130. Identification of Epigallocatechin-3- Gallate as an Inhibitor of Phosphoglycerate Mutase 1

    Article • Frontiers in Pharmacology, May 2017, Frontiers

    Professor Yongzhuo Huang

  131. Codelivery of dihydroartemisinin and doxorubicin in mannosylated liposomes for drug-resistant colon cancer therapy

    Article • Acta Pharmacologica Sinica, May 2017, Nature

    Professor Yongzhuo Huang

  132. Tandem-multimeric F3-gelonin fusion toxins for enhanced anti-cancer activity for prostate cancer treatment

    Article • International Journal of Pharmaceutics, May 2017, Elsevier

    Professor Yongzhuo Huang

  133. Prodrug-Like, PEGylated Protein Toxin Trichosanthin for Reversal of Chemoresistance

    Article • Molecular Pharmaceutics, February 2017, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  134. Intein-mediated site-specific synthesis of tumor-targeting protein delivery system: Turning PEG dilemma into prodrug-like feature

    Article • Biomaterials, February 2017, Elsevier

    Professor Yongzhuo Huang

  135. Albumin Biomimetic Nanocorona Improves Tumor Targeting and Penetration for Synergistic Therapy of Metastatic Breast Cancer

    Article • Advanced Functional Materials, January 2017, Wiley

    Professor Yongzhuo Huang

  136. Poly-γ-glutamic acid-based GGT-targeting and surface camouflage strategy for improving cervical cancer gene therapy

    Article • Journal of Materials Chemistry B, January 2017, Royal Society of Chemistry

    Professor Yongzhuo Huang

  137. A mannosylated PEI–CPP hybrid for TRAIL gene targeting delivery for colorectal cancer therapy

    Article • Polymer Chemistry, January 2017, Royal Society of Chemistry

    Professor Yongzhuo Huang

  138. High-Yield Synthesis of Monomeric LMWP(CPP)-siRNA Covalent Conjugate for Effective Cytosolic Delivery of siRNA

    Article • Theranostics, January 2017, Ivyspring International Publisher

    Professor Yongzhuo Huang

  139. Glioma Dual-Targeting Nanohybrid Protein Toxin Constructed by Intein-Mediated Site-Specific Ligation for Multistage Booster Delivery

    Article • Theranostics, January 2017, Ivyspring International Publisher

    Professor Yongzhuo Huang

  140. Nanotechnology-based combination therapy for overcoming multidrug-resistant cancer

    Article • Cancer Biology and Medicine, January 2017, Cancer Biology and Medicine

    Professor Yongzhuo Huang

  141. Heparin-Regulated Prodrug-Type Macromolecular Theranostic Systems for Cancer Therapy

    Article • Nanotheranostics, January 2017, Ivyspring International Publisher

    Professor Yongzhuo Huang

  142. Dual-Targeting Magnetic PLGA Nanoparticles for Codelivery of Paclitaxel and Curcumin for Brain Tumor Therapy

    Article • ACS Applied Materials & Interfaces, November 2016, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  143. Blood–Brain-Barrier-Penetrating Albumin Nanoparticles for Biomimetic Drug Delivery via Albumin-Binding Protein Pathways for Antiglioma Therapy

    Article • ACS Nano, November 2016, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  144. Pharmacokinetics and Pharmacodynamics (PK/PD) of Bionanomaterials

    Article • August 2016, Wiley

    Professor Yongzhuo Huang

  145. Nuclear-targeting TAT-PEG-Asp8-doxorubicin polymeric nanoassembly to overcome drug-resistant colon cancer

    Article • Acta Pharmacologica Sinica, June 2016, Nature

    Professor Yongzhuo Huang

  146. Preparation and Characterization of Gelonin-Melittin Fusion Biotoxin for Synergistically Enhanced Anti-Tumor Activity

    Article • Pharmaceutical Research, June 2016, Springer Science + Business Media

    Professor Yongzhuo Huang

  147. Nose-to-brain delivery of macromolecules mediated by cell-penetrating peptides

    Article • Acta Pharmaceutica Sinica B, May 2016, Elsevier

    Professor Yongzhuo Huang

  148. Intracellularly Acid-Switchable Multifunctional Micelles for Combinational Photo/Chemotherapy of the Drug-Resistant Tumor

    Article • ACS Nano, March 2016, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  149. Gene Delivery: Fusogenic Reactive Oxygen Species Triggered Charge-Reversal Vector for Effective Gene Delivery (Adv. Mater. 9/2016)

    Article • Advanced Materials, March 2016, Wiley

    Professor Yongzhuo Huang

  150. Hydrothermal Synthesis and Biocompatibility Study of Highly Crystalline Carbonated Hydroxyapatite Nanorods

    Article • January 2016, De Gruyter

    Professor Yongzhuo Huang

  151. Fusogenic Reactive Oxygen Species Triggered Charge-Reversal Vector for Effective Gene Delivery

    Article • Advanced Materials, December 2015, Wiley

    Professor Yongzhuo Huang

  152. Bioreducible Micelles with Endosomal Buffering and Multidrug Resistance-Reversing Function Enhance Anti-Tumor Efficacy of Doxorubicin

    Article • Journal of Biomedical Nanotechnology, October 2015, American Scientific Publishers

    Professor Yongzhuo Huang

  153. Hydrothermal Synthesis and Biocompatibility Study of Highly Crystalline Carbonated Hydroxyapatite Nanorods

    Article • Nanoscale Research Letters, August 2015, Springer Science + Business Media

    Professor Yongzhuo Huang

  154. Inhibition of metastasis and growth of breast cancer by pH-sensitive poly (β-amino ester) nanoparticles co-delivering two siRNA and paclitaxel

    Article • Biomaterials, April 2015, Elsevier

    Professor Yongzhuo Huang

  155. Codelivery of Sorafenib and Curcumin by Directed Self-Assembled Nanoparticles Enhances Therapeutic Effect on Hepatocellular Carcinoma

    Article • Molecular Pharmaceutics, March 2015, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  156. PTD-Modified ATTEMPTS for Enhanced Toxin-based Cancer Therapy: An In Vivo Proof-of-Concept Study

    Article • Pharmaceutical Research, February 2015, Springer Science + Business Media

    Professor Yongzhuo Huang

  157. Microneedle-assisted dendritic cell-targeted nanoparticles for transcutaneous DNA immunization

    Article • Polymer Chemistry, January 2015, Royal Society of Chemistry

    Professor Yongzhuo Huang

  158. Recent progress in microRNA delivery for cancer therapy by non-viral synthetic vectors

    Article • Advanced Drug Delivery Reviews, January 2015, Elsevier

    Professor Yongzhuo Huang

  159. Green synthesis of hyaluronic acid-based silver nanoparticles and their enhanced delivery to CD44+ cancer cells

    Article • RSC Advances, January 2015, Royal Society of Chemistry

    Professor Yongzhuo Huang

  160. A Prodrug-type, MMP-2-targeting Nanoprobe for Tumor Detection and Imaging

    Article • Theranostics, January 2015, Ivyspring International Publisher

    Professor Yongzhuo Huang

  161. Molecular-Dynamics-Simulation-Driven Design of a Protease-Responsive Probe for In-Vivo Tumor Imaging

    Article • Advanced Materials, October 2014, Wiley

    Professor Yongzhuo Huang

  162. Cell-Penetrating Apoptotic Peptide/p53 DNA Nanocomplex as Adjuvant Therapy for Drug-Resistant Breast Cancer

    Article • Molecular Pharmaceutics, October 2014, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  163. Low-molecular-weight protamine-modified PLGA nanoparticles for overcoming drug-resistant breast cancer

    Article • Journal of Controlled Release, October 2014, Elsevier

    Professor Yongzhuo Huang

  164. Editorial (Thematic Issue: “Cell-penetrating Peptides and Drug Delivery”)

    Article • Current Pharmaceutical Biotechnology, August 2014, Bentham Science Publishers

    Professor Yongzhuo Huang

  165. Cell-Penetrating Peptide-Mediated Topical Delivery of Biomacromolecular Drugs

    Article • Current Pharmaceutical Biotechnology, August 2014, Bentham Science Publishers

    Professor Yongzhuo Huang

  166. CPP-mediated Protein Delivery in a Noncovalent Form: Proof-of-Concept for Percutaneous and Intranasal Delivery

    Article • Protein and Peptide Letters, August 2014, Bentham Science Publishers

    Professor Yongzhuo Huang

  167. Drug Delivery and Reversal of MDR

    Article • Molecular Pharmaceutics, August 2014, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  168. Doxorubicin and Lapatinib Combination Nanomedicine for Treating Resistant Breast Cancer

    Article • Molecular Pharmaceutics, August 2014, American Chemical Society (ACS)

    Professor Yongzhuo Huang

  169. Protease-Activatable Hybrid Nanoprobe for Tumor Imaging

    Article • Advanced Functional Materials, July 2014, Wiley

    Professor Yongzhuo Huang

  170. Co-delivery of doxorubicin and RNA using pH-sensitive poly (β-amino ester) nanoparticles for reversal of multidrug resistance of breast cancer

    Article • Biomaterials, July 2014, Elsevier

    Professor Yongzhuo Huang

  171. Epirubicin-Loaded Superparamagnetic Iron-Oxide Nanoparticles for Transdermal Delivery: Cancer Therapy by Circumventing the Skin Barrier

    Article • Small, June 2014, Wiley

    Professor Yongzhuo Huang

  172. Recombinant TAT-gelonin fusion toxin: Synthesis and characterization of heparin/protamine-regulated cell transduction

    Article • Journal of Biomedical Materials Research Part A, April 2014, Wiley

    Professor Yongzhuo Huang

  173. The use of low molecular weight protamine chemical chimera to enhance monomeric insulin intestinal absorption

    Article • Biomaterials, October 2013, Elsevier

    Professor Yongzhuo Huang

  174. Curb challenges of the “Trojan Horse” approach: Smart strategies in achieving effective yet safe cell-penetrating peptide-based drug delivery

    Article • Advanced Drug Delivery Reviews, October 2013, Elsevier

    Professor Yongzhuo Huang

  175. Co-delivery of Cell-permeable Chimeric Apoptosis AVPIR8Peptide/p53 DNA for Cocktail Therapy

    Article • Advanced Functional Materials, July 2013, Wiley

    Professor Yongzhuo Huang

  176. Ultrasound-mediated targeted microbubbles: a new vehicle for cancer therapy

    Article • Frontiers of Chemical Science and Engineering, January 2013, Springer Science + Business Media

    Professor Yongzhuo Huang

  177. Overcoming oral insulin delivery barriers: application of cell penetrating peptide and silica-based nanoporous composites

    Article • Frontiers of Chemical Science and Engineering, January 2013, Springer Science + Business Media

    Professor Yongzhuo Huang

  178. Magnetic Nanoparticles for Tumor Imaging and Therapy: A So-Called Theranostic System

    Article • Pharmaceutical Research, January 2013, Springer Science + Business Media

    Professor Yongzhuo Huang

  179. Pluronic L61 as a long-circulating modifier for enhanced liposomal delivery of cancer drugs

    Article • Polymer Chemistry, January 2013, Royal Society of Chemistry

    Professor Yongzhuo Huang

  180. Cell-penetrating albumin conjugates for enhanced doxorubicin delivery

    Article • Polymer Chemistry, January 2013, Royal Society of Chemistry

    Professor Yongzhuo Huang

  181. Template synthesis of PMAA@chitosan hollow nanorods for docetaxel delivery

    Article • Polymer Chemistry, January 2013, Royal Society of Chemistry

    Professor Yongzhuo Huang

  182. Cell-penetrating peptide-modified PLGA nanoparticles for enhanced nose-to-brain macromolecular delivery

    Article • Macromolecular Research, October 2012, Springer Science + Business Media

    Professor Yongzhuo Huang

  183. Magnetic Nanoparticles for MRI of Brain Tumors

    Article • Current Pharmaceutical Biotechnology, October 2012, Bentham Science Publishers

    Professor Yongzhuo Huang

  184. TAT-modified nanosilver for combating multidrug-resistant cancer

    Article • Biomaterials, September 2012, Elsevier

    Professor Yongzhuo Huang

  185. Multifunctional drug delivery system for targeting tumor and its acidic microenvironment

    Article • Journal of Controlled Release, August 2012, Elsevier

    Professor Yongzhuo Huang

  186. In vivo delivery of cell-permeable antisense hypoxia-inducible factor 1α oligonucleotide to adipose tissue reduces adiposity in obese mice

    Article • Journal of Controlled Release, July 2012, Elsevier

    Professor Yongzhuo Huang

  187. Skin-permeable quaternary nanoparticles with layer-by-layer structure enabling improved gene delivery

    Article • Journal of Materials Chemistry, January 2012, Royal Society of Chemistry

    Professor Yongzhuo Huang

  188. An injectable hybrid nanoparticle-in-oil-in-water submicron emulsion for improved delivery of poorly soluble drugs

    Article • Nanoscale Research Letters, January 2012, Springer Science + Business Media

    Professor Yongzhuo Huang

  189. Low molecular weight protamine/insulin formulation with potential to attenuate protamine-masqueraded insulin allergy

    Article • Macromolecular Research, November 2011, Springer Science + Business Media

    Professor Yongzhuo Huang

  190. Downregulation of survivin expression and enhanced chemosensitivity of MCF-7 cells to adriamycin by PDMAE/survivin shRNA complex nanoparticles

    Article • International Journal of Pharmaceutics, February 2011, Elsevier

    Professor Yongzhuo Huang

  191. Polysorbate cationic synthetic vesicle for gene delivery

    Article • Journal of Biomedical Materials Research Part A, January 2011, Wiley

    Professor Yongzhuo Huang

  192. An in situ-forming, solid lipid/PLGA hybrid implant for long-acting antipsychotics

    Article • Soft Matter, January 2011, Royal Society of Chemistry

    Professor Yongzhuo Huang

  193. Co-administration of protein drugs with gold nanoparticles to enable percutaneous delivery

    Article • Biomaterials, December 2010, Elsevier

    Professor Yongzhuo Huang

  194. The magnetophoretic mobility and superparamagnetism of core-shell iron oxide nanoparticles with dual targeting and imaging functionality

    Article • Biomaterials, August 2010, Elsevier

    Professor Yongzhuo Huang

  195. ATTEMPTS System: A Macromolecular Prodrug Strategy for Cancer Drug Delivery

    Article • Current Pharmaceutical Design, July 2010, Bentham Science Publishers

    Professor Yongzhuo Huang

  196. Alginate–Chitosan–PLGA Composite Microspheres Enabling Single-Shot Hepatitis B Vaccination

    Article • The AAPS Journal, June 2010, American Association of Pharmaceutical Scientists (AAPS)

    Professor Yongzhuo Huang

  197. Specific down regulation of 3T3-L1 adipocyte differentiation by cell-permeable antisense HIF1α-oligonucleotide

    Article • Journal of Controlled Release, May 2010, Elsevier

    Professor Yongzhuo Huang

  198. Niosomal Delivery System for Macromolecular Drugs

    Article • March 2010, Taylor & Francis

    Professor Yongzhuo Huang

  199. Synthetic Skin-Permeable Proteins Enabling Needleless Immunization

    Article • Angewandte Chemie, March 2010, Wiley

    Professor Yongzhuo Huang

  200. Synthetic Skin-Permeable Proteins Enabling Needleless Immunization

    Article • Angewandte Chemie, March 2010, Wiley

    Professor Yongzhuo Huang

  201. The artificial peroxidase activity of magnetic iron oxide nanoparticles and its application to glucose detection

    Article • Biomaterials, September 2009, Elsevier

    Professor Yongzhuo Huang

  202. The ATTEMPTS delivery systems for macromolecular drugs

    Article • Expert Opinion on Drug Delivery, November 2008, Informa Healthcare

    Professor Yongzhuo Huang

  203. A hybrid thermo-sensitive chitosan gel for sustained release of Meloxicam

    Article • Journal of Biomaterials Science Polymer Edition, January 2008, Taylor & Francis

    Professor Yongzhuo Huang

  204. Glioma selectivity of magnetically targeted nanoparticles: A role of abnormal tumor hydrodynamics

    Article • Journal of Controlled Release, October 2007, Elsevier

    Professor Yongzhuo Huang

  205. PEGylated synthetic surfactant vesicles (Niosomes): novel carriers for oligonucleotides

    Article • Journal of Materials Science Materials in Medicine, July 2007, Springer Science + Business Media

    Professor Yongzhuo Huang

  206. Cationic liposomes modified with non-ionic surfactants as effective non-viral carrier for gene transfer

    Article • Colloids and Surfaces B Biointerfaces, May 2006, Elsevier

    Professor Yongzhuo Huang

  207. Preparation and Characterization of Liposomes Encapsulating Chitosan Nanoparticles

    Article • Biological and Pharmaceutical Bulletin, January 2005, Pharmaceutical Society of Japan

    Professor Yongzhuo Huang