All Stories

  1. A Drug-Free Polysaccharide Hydrogel Encapsulating Iron Oxide Nanoparticles against Postoperative Tumor Recurrence and Metastasis
  2. Turning aging cells into a live vaccine: engineered senescent cancer cells with adjuvant celecoxib for immunotherapy
  3. Phospholipid complex-based microemulsion for treating concurrence of primary sclerosing cholangitis and inflammatory bowel disease via gut-liver crosstalk
  4. Inhalable Inclusion Cocrystal of Exocarpium Citri Grandis Volatile Oil for Treatment of Acute Lung Injury
  5. Biomimetically engineered plant-derived exosomes-like nanovesicles for rheumatoid arthritis therapy
  6. Ascorbic Acid-Derived Supramolecular Gels Induce Immunogenic Ferroptosis in Cancer Cells to Potentiate Tumor Immunotherapy
  7. Drug Repurposing with Topical Paclitaxel Delivery for Psoriasis Treatment Enabled by Plant-Inspired Molecular Assembly
  8. Ion-Gradient Driven Drug-Loading Liposomes for Codelivery of Shikonin/Regorafenib for Cancer Immunometabolic Therapy and Postoperative Intervention
  9. Nanohydroxyapatite-Stabilized Pickering-Emulsion-Incorporated Hydrogel Prevents Postoperative Osteosarcoma Recurrence and Promotes Bone Repair
  10. A bigel co-delivering highly hydrophilic and hydrophobic natural compounds for enhanced ulcerative colitis therapy
  11. Microalgae-carrying nanomedicine for bioadhesive drug delivery for treating chemotherapy-induced intestinal injury
  12. Targeting stem-property and vasculogenic mimicry for sensitizing paclitaxel therapy of triple-negative breast cancer by biomimetic codelivery
  13. In-situ trichosanthin-IL2/pectin dynamic hydrogel activates dendritic cells and reverses T cell exhaustion for post-operative cancer therapy
  14. An enhanced bioactive chitosan-modified microemulsion for mucosal healing of ulcerative colitis
  15. Natural product-integrated microneedle patch for rheumatoid arthritis treatment through anti-inflammation and angiogenesis suppression
  16. Co-delivery of TRAIL DNA and salinomycin for cancer therapy via enhanced apoptosis and cancer stemness inhibition
  17. Cellular vesicles-based “all-in-one” vaccine platform triggers mucosal immunity against respiratory viruses
  18. Intratumoral lactic acid neutralization strategy for boosting chemoimmunotherapy using liposomal sodium bicarbonate
  19. Carrier Polymer-Free Dissolvable Microneedles Enable Superhigh Drug Payload for Percutaneous Protein Delivery
  20. Uncovering key mechanisms and intervention therapies in aging skin
  21. Alginate/silk fibroin/Zn2+ composite microspheres for site-specific delivery for enhanced ulcerative colitis therapy
  22. Coronavirus spike protein-based vaccines. Vaccine delivery systems
  23. Aggregation-caused quenching to crystallization-induced emission transformation: hydration-induced luminescence in crystal curcumin with tunable thermochromism for in vivo tracking
  24. Immunometabolic rewiring in macrophages for periodontitis treatment via nanoquercetin-mediated leverage of glycolysis and OXPHOS
  25. Albumin is a reliable drug-delivering molecule: Highlighting points in cancer therapy
  26. Interactions between nanoparticles and lymphatic systems: Mechanisms and applications in drug delivery
  27. A Spatially Stable Crystal-Particle Gel to Trap Patchouli Oil for Efficient Colonic Drug Delivery
  28. Gastroretentive Raft Forming System for Enhancing Therapeutic Effect of Drug‐Loaded Hollow Mesoporous Silica on Gastric Ulcers
  29. Naturally sourced amphiphilic peptides as paclitaxel vehicles for breast cancer treatment
  30. Biomimetic nano-chelate diethyldithiocarbamate Cu/Fe for enhanced metalloimmunity and ferroptosis activation in glioma therapy
  31. Asiatic acid cyclodextrin inclusion micro-cocrystal for insoluble drug delivery and acute lung injury therapy enhancement
  32. Heparin-Conjugated ACE2-Bearing Extracellular Vesicles As Engineered Dual-Decoy for Combating the SARS-CoV-2 Omicron Variant via Pulmonary Delivery
  33. Blocking tumor-platelet crosstalk to prevent tumor metastasis via reprograming glycolysis using biomimetic membrane-hybridized liposomes
  34. Environment-responsive dendrobium polysaccharide hydrogel embedding manganese microsphere as a post-operative adjuvant to boost cascaded immune cycle against melanoma
  35. Tumor-Associated Macrophage Targeting of Nanomedicines in Cancer Therapy
  36. Epigenetic-based combination therapy and liposomal codelivery overcomes osimertinib-resistant NSCLC via repolarizing tumor-associated macrophages
  37. Rational design of oral delivery nanosystems for hypoglycemic peptides
  38. Pathologically catalyzed physical coating restores the intestinal barrier for inflammatory bowel disease therapy
  39. Author correction to “Neutralization of SARS-CoV-2 pseudovirus using ACE2-engineered extracellular vesicles” [Acta Pharmaceutica Sinica B 12 (2022) 1523–1533]
  40. Liposomal Resveratrol Alleviates Platelet Storage Lesion via Antioxidation and the Physical Buffering Effect
  41. Mitigation of Anti‐Drug Antibody Production for Augmenting Anticancer Efficacy of Therapeutic Protein via Co‐Injection of Nano‐Rapamycin
  42. Oral pectin/oligochitosan microspheres for colon-specific controlled release of quercetin to treat inflammatory bowel disease
  43. Correction to “Lactoferrin-Modified Gambogic Acid Liposomes for Colorectal Cancer Treatment”
  44. Cyclodextrin-Coordinated Liposome-in-Gel for Transcutaneous Quercetin Delivery for Psoriasis Treatment
  45. Lactoferrin-Modified Gambogic Acid Liposomes for Colorectal Cancer Treatment
  46. Targeting lactate metabolism and immune interaction in breast tumor via protease-triggered delivery
  47. Carbohydrate Strengthens the Immunotherapeutic Effect of Small-Molecule PD-L1 Inhibitors
  48. Cell penetrating peptides: Highlighting points in cancer therapy
  49. Regulating lactate-related immunometabolism and EMT reversal for colorectal cancer liver metastases using shikonin targeted delivery
  50. Toad venom bufadienolides and bufotoxins: An updated review
  51. Living Cells and Cell-Derived Vesicles: A Trojan Horse Technique for Brain Delivery
  52. Topical Delivery of Cell-Penetrating Peptide-Modified Human Growth Hormone for Enhanced Wound Healing
  53. Pharmaceutical liposomal delivery—specific considerations of innovation and challenges
  54. Recombinant cell-penetrating trichosanthin synergizes anti-PD-1 therapy in colorectal tumor
  55. Targeting glycolysis for cancer therapy using drug delivery systems
  56. Mannosylated engineered trichosanthin-legumain protein vaccine hydrogel for breast cancer immunotherapy
  57. Intracellular delivery of messenger RNA to macrophages with surfactant-derived lipid nanoparticles
  58. Localized delivery of nanomedicine and antibodies for combating COVID-19
  59. “Two-birds-one-stone” colon-targeted nanomedicine treats ulcerative colitis via remodeling immune microenvironment and anti-fibrosis
  60. Gold Nanocage-Based Photothermal Ablation Facilitates In Situ Vaccination for Melanoma Therapy
  61. Evaluation of Transdermal Transport and Concurrent Cutaneous Hydrolysis of Timolol Prodrug for the Treatment of Infantile Hemangiomas
  62. Nanoplateletsomes restrain metastatic tumor formation through decoy and active targeting in a preclinical mouse model
  63. Advances on Delivery of Cytotoxic Enzymes as Anticancer Agents
  64. Anti-alcoholism drug disulfiram for targeting glioma energy metabolism using BBB-penetrating delivery of fixed-dose combination
  65. Brain-targeting biomimetic nanoparticles for codelivery of celastrol and LY2157299 for reversing glioma immunosuppression
  66. Lipid Metabolism Regulation Based on Nanotechnology for Enhancement of Tumor Immunity
  67. A drug-free nanozyme for mitigating oxidative stress and inflammatory bowel disease
  68. Inhaled heparin polysaccharide nanodecoy against SARS-CoV-2 and variants
  69. Nanotherapeutic macrophage-based immunotherapy for the peritoneal carcinomatosis of lung cancer
  70. In Situ Pathologically Catalyzed Polydopamine Coating Enhances the Intestinal Barrier for Inflammatory Bowel Disease Therapy
  71. Remodeling immune microenvironment in periodontitis using resveratrol liposomes as an antibiotic-free therapeutic strategy
  72. Recombinant cancer nanovaccine for targeting tumor-associated macrophage and remodeling tumor microenvironment
  73. Disulfiram-loaded lactoferrin nanoparticles for treating inflammatory diseases
  74. Neutralization of SARS-CoV-2 pseudovirus using ACE2-engineered extracellular vesicles
  75. Remodeling “cold” tumor immune microenvironment via epigenetic-based therapy using targeted liposomes with in situ formed albumin corona
  76. Genetically-engineered “all-in-one” vaccine platform for cancer immunotherapy
  77. Teaching new tricks to old dogs: A review of drug repositioning of disulfiram for cancer nanomedicine
  78. Biomimetic camouflage delivery strategies for cancer therapy
  79. Magnetism-mediated targeting hyperthermia-immunotherapy in “cold” tumor with CSF1R inhibitor
  80. Biomimetic codelivery overcomes osimertinib-resistant NSCLC and brain metastasis via macrophage-mediated innate immunity
  81. Anti-PD-L1 mediating tumor-targeted codelivery of liposomal irinotecan/JQ1 for chemo-immunotherapy
  82. Metabolic modulation via mTOR pathway and anti-angiogenesis remodels tumor microenvironment using PD-L1-targeting codelivery
  83. Lactoferrin-mediated macrophage targeting delivery and patchouli alcohol-based therapeutic strategy for inflammatory bowel diseases
  84. Remodeling tumor immune microenvironment (TIME) for glioma therapy using multi-targeting liposomal codelivery
  85. Publisher Correction: ‘TRAIL-based gene delivery and therapeutic strategies’ and ‘Overview of recent advances in liposomal nanoparticle-based cancer immunotherapy’
  86. Nanotechnology-Based Histone Deacetylase Inhibitors for Cancer Therapy
  87. Dual‐Targeting to Cancer Cells and M2 Macrophages via Biomimetic Delivery of Mannosylated Albumin Nanoparticles for Drug‐Resistant Cancer Therapy
  88. Biomimetic metal-organic nanoparticles prepared with a 3D-printed microfluidic device as a novel formulation for disulfiram-based therapy against breast cancer
  89. A Trojan horse biomimetic delivery strategy using mesenchymal stem cells for PDT/PTT therapy against lung melanoma metastasis
  90. Macrophage-based nanotherapeutic strategies in ulcerative colitis
  91. Deformable liposomal codelivery of vorinostat and simvastatin promotes antitumor responses through remodeling tumor microenvironment
  92. BBB-penetrating codelivery liposomes treat brain metastasis of non-small cell lung cancer with EGFRT790M mutation
  93. Correction: A Trojan horse biomimetic delivery strategy using mesenchymal stem cells for PDT/PTT therapy against lung melanoma metastasis
  94. Introduction to biomimetic therapeutics
  95. Correction to Co-Delivery of Trichosanthin and Albendazole by Nano-Self-Assembly for Overcoming Tumor Multidrug-Resistance and Metastasis
  96. Advances on Tumor-Targeting Delivery of Cytotoxic Proteins
  97. Correction to Codelivery of Sorafenib and Curcumin by Directed Self-Assembled Nanoparticles Enhances Therapeutic Effect on Hepatocellular Carcinoma
  98. Recent progress in drug delivery
  99. TRAIL-based gene delivery and therapeutic strategies
  100. Menthol-modified BSA nanoparticles for glioma targeting therapy using an energy restriction strategy
  101. Trained Macrophage Bioreactor for Penetrating Delivery of Fused Antitumor Protein
  102. Transcutaneous Delivery of DNA/mRNA for Cancer Therapeutic Vaccination
  103. Reprogramming Tumor Immune Microenvironment (TIME) and Metabolism via Biomimetic Targeting Codelivery of Shikonin/JQ1
  104. Genetically-engineered protein prodrug-like nanoconjugates for tumor-targeting biomimetic delivery via a SHEATH strategy
  105. Targeting lipid metabolism to overcome EMT-associated drug resistance via integrin β3/FAK pathway and tumor-associated macrophage repolarization using legumain-activatable delivery
  106. The intra-brain distribution of brain targeting delivery systems
  107. Nano-Structural Effects on Gene Transfection: Large, Botryoid-Shaped Nanoparticles Enhance DNA Delivery via Macropinocytosis and Effective Dissociation
  108. Disulfiram Copper Nanoparticles Prepared with a Stabilized Metal Ion Ligand Complex Method for Treating Drug-Resistant Prostate Cancers
  109. Remodeling Tumor-Associated Macrophages and Neovascularization Overcomes EGFRT790M -Associated Drug Resistance by PD-L1 Nanobody-Mediated Codelivery
  110. The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis
  111. Natural Brain Penetration Enhancer-Modified Albumin Nanoparticles for Glioma Targeting Delivery
  112. Tat-functionalized Ag-Fe 3 O 4 nano-composites as tissue-penetrating vehicles for tumor magnetic targeting and drug delivery
  113. Antiglioma via regulating oxidative stress and remodeling tumor-associated macrophage using lactoferrin-mediated biomimetic codelivery of simvastatin/fenretinide
  114. Roles of Albumin-Binding Proteins in Cancer Progression and Biomimetic Targeted Drug Delivery
  115. A novel tumor-targeting treatment strategy uses energy restriction via co-delivery of albendazole and nanosilver
  116. Liposomal Codelivery of Doxorubicin and Andrographolide Inhibits Breast Cancer Growth and Metastasis
  117. Targeting death receptors for drug-resistant cancer therapy: Codelivery of pTRAIL and monensin using dual-targeting and stimuli-responsive self-assembling nanocomposites
  118. Macrophage-Membrane-Coated Nanoparticles for Tumor-Targeted Chemotherapy
  119. Improved Protein Toxin Delivery Based on ATTEMPTS Systems
  120. Dual-targeting biomimetic delivery for anti-glioma activityviaremodeling the tumor microenvironment and directing macrophage-mediated immunotherapy
  121. Biomimetic albumin-modified gold nanorods for photothermo-chemotherapy and macrophage polarization modulation
  122. Improved method for synthesis of low molecular weight protamine–siRNA conjugate
  123. Smart Cell-Penetrating Peptide-Based Techniques for Intracellular Delivery of Therapeutic Macromolecules
  124. Reprogramming Tumor-Associated Macrophages To Reverse EGFRT790M Resistance by Dual-Targeting Codelivery of Gefitinib/Vorinostat
  125. Cell-penetrating peptide-based non-invasive topical delivery systems
  126. Application of Monodisperse PEGs in Pharmaceutics: Monodisperse Polidocanols
  127. Co-Delivery of Trichosanthin and Albendazole by Nano-Self-Assembly for Overcoming Tumor Multidrug-Resistance and Metastasis
  128. Two-birds-one-stone delivery and therapeutic strategy for overcoming chemtherapy resistance
  129. Cancer nanobiotechnolgy
  130. Microneedle-Assisted, DC-Targeted Codelivery of pTRP-2 and Adjuvant of Paclitaxel for Transcutaneous Immunotherapy
  131. Identification of Epigallocatechin-3- Gallate as an Inhibitor of Phosphoglycerate Mutase 1
  132. Codelivery of dihydroartemisinin and doxorubicin in mannosylated liposomes for drug-resistant colon cancer therapy
  133. Tandem-multimeric F3-gelonin fusion toxins for enhanced anti-cancer activity for prostate cancer treatment
  134. Prodrug-Like, PEGylated Protein Toxin Trichosanthin for Reversal of Chemoresistance
  135. Intein-mediated site-specific synthesis of tumor-targeting protein delivery system: Turning PEG dilemma into prodrug-like feature
  136. Albumin Biomimetic Nanocorona Improves Tumor Targeting and Penetration for Synergistic Therapy of Metastatic Breast Cancer
  137. Poly-γ-glutamic acid-based GGT-targeting and surface camouflage strategy for improving cervical cancer gene therapy
  138. A mannosylated PEI–CPP hybrid for TRAIL gene targeting delivery for colorectal cancer therapy
  139. High-Yield Synthesis of Monomeric LMWP(CPP)-siRNA Covalent Conjugate for Effective Cytosolic Delivery of siRNA
  140. Glioma Dual-Targeting Nanohybrid Protein Toxin Constructed by Intein-Mediated Site-Specific Ligation for Multistage Booster Delivery
  141. Nanotechnology-based combination therapy for overcoming multidrug-resistant cancer
  142. Heparin-Regulated Prodrug-Type Macromolecular Theranostic Systems for Cancer Therapy
  143. Dual-Targeting Magnetic PLGA Nanoparticles for Codelivery of Paclitaxel and Curcumin for Brain Tumor Therapy
  144. Blood–Brain-Barrier-Penetrating Albumin Nanoparticles for Biomimetic Drug Delivery via Albumin-Binding Protein Pathways for Antiglioma Therapy
  145. Pharmacokinetics and Pharmacodynamics (PK/PD) of Bionanomaterials
  146. Nuclear-targeting TAT-PEG-Asp8-doxorubicin polymeric nanoassembly to overcome drug-resistant colon cancer
  147. Preparation and Characterization of Gelonin-Melittin Fusion Biotoxin for Synergistically Enhanced Anti-Tumor Activity
  148. Nose-to-brain delivery of macromolecules mediated by cell-penetrating peptides
  149. Intracellularly Acid-Switchable Multifunctional Micelles for Combinational Photo/Chemotherapy of the Drug-Resistant Tumor
  150. Gene Delivery: Fusogenic Reactive Oxygen Species Triggered Charge-Reversal Vector for Effective Gene Delivery (Adv. Mater. 9/2016)
  151. Hydrothermal Synthesis and Biocompatibility Study of Highly Crystalline Carbonated Hydroxyapatite Nanorods
  152. Fusogenic Reactive Oxygen Species Triggered Charge-Reversal Vector for Effective Gene Delivery
  153. Bioreducible Micelles with Endosomal Buffering and Multidrug Resistance-Reversing Function Enhance Anti-Tumor Efficacy of Doxorubicin
  154. Hydrothermal Synthesis and Biocompatibility Study of Highly Crystalline Carbonated Hydroxyapatite Nanorods
  155. Inhibition of metastasis and growth of breast cancer by pH-sensitive poly (β-amino ester) nanoparticles co-delivering two siRNA and paclitaxel
  156. Codelivery of Sorafenib and Curcumin by Directed Self-Assembled Nanoparticles Enhances Therapeutic Effect on Hepatocellular Carcinoma
  157. PTD-Modified ATTEMPTS for Enhanced Toxin-based Cancer Therapy: An In Vivo Proof-of-Concept Study
  158. Microneedle-assisted dendritic cell-targeted nanoparticles for transcutaneous DNA immunization
  159. Recent progress in microRNA delivery for cancer therapy by non-viral synthetic vectors
  160. Green synthesis of hyaluronic acid-based silver nanoparticles and their enhanced delivery to CD44+ cancer cells
  161. A Prodrug-type, MMP-2-targeting Nanoprobe for Tumor Detection and Imaging
  162. Molecular-Dynamics-Simulation-Driven Design of a Protease-Responsive Probe for In-Vivo Tumor Imaging
  163. Cell-Penetrating Apoptotic Peptide/p53 DNA Nanocomplex as Adjuvant Therapy for Drug-Resistant Breast Cancer
  164. Low-molecular-weight protamine-modified PLGA nanoparticles for overcoming drug-resistant breast cancer
  165. Editorial (Thematic Issue: “Cell-penetrating Peptides and Drug Delivery”)
  166. Cell-Penetrating Peptide-Mediated Topical Delivery of Biomacromolecular Drugs
  167. CPP-mediated Protein Delivery in a Noncovalent Form: Proof-of-Concept for Percutaneous and Intranasal Delivery
  168. Drug Delivery and Reversal of MDR
  169. Doxorubicin and Lapatinib Combination Nanomedicine for Treating Resistant Breast Cancer
  170. Protease-Activatable Hybrid Nanoprobe for Tumor Imaging
  171. Co-delivery of doxorubicin and RNA using pH-sensitive poly (β-amino ester) nanoparticles for reversal of multidrug resistance of breast cancer
  172. Epirubicin-Loaded Superparamagnetic Iron-Oxide Nanoparticles for Transdermal Delivery: Cancer Therapy by Circumventing the Skin Barrier
  173. Recombinant TAT-gelonin fusion toxin: Synthesis and characterization of heparin/protamine-regulated cell transduction
  174. The use of low molecular weight protamine chemical chimera to enhance monomeric insulin intestinal absorption
  175. Curb challenges of the “Trojan Horse” approach: Smart strategies in achieving effective yet safe cell-penetrating peptide-based drug delivery
  176. Co-delivery of Cell-permeable Chimeric Apoptosis AVPIR8Peptide/p53 DNA for Cocktail Therapy
  177. Ultrasound-mediated targeted microbubbles: a new vehicle for cancer therapy
  178. Overcoming oral insulin delivery barriers: application of cell penetrating peptide and silica-based nanoporous composites
  179. Magnetic Nanoparticles for Tumor Imaging and Therapy: A So-Called Theranostic System
  180. Pluronic L61 as a long-circulating modifier for enhanced liposomal delivery of cancer drugs
  181. Cell-penetrating albumin conjugates for enhanced doxorubicin delivery
  182. Template synthesis of PMAA@chitosan hollow nanorods for docetaxel delivery
  183. Cell-penetrating peptide-modified PLGA nanoparticles for enhanced nose-to-brain macromolecular delivery
  184. Magnetic Nanoparticles for MRI of Brain Tumors
  185. TAT-modified nanosilver for combating multidrug-resistant cancer
  186. Multifunctional drug delivery system for targeting tumor and its acidic microenvironment
  187. In vivo delivery of cell-permeable antisense hypoxia-inducible factor 1α oligonucleotide to adipose tissue reduces adiposity in obese mice
  188. Skin-permeable quaternary nanoparticles with layer-by-layer structure enabling improved gene delivery
  189. An injectable hybrid nanoparticle-in-oil-in-water submicron emulsion for improved delivery of poorly soluble drugs
  190. Low molecular weight protamine/insulin formulation with potential to attenuate protamine-masqueraded insulin allergy
  191. Downregulation of survivin expression and enhanced chemosensitivity of MCF-7 cells to adriamycin by PDMAE/survivin shRNA complex nanoparticles
  192. Polysorbate cationic synthetic vesicle for gene delivery
  193. An in situ-forming, solid lipid/PLGA hybrid implant for long-acting antipsychotics
  194. Co-administration of protein drugs with gold nanoparticles to enable percutaneous delivery
  195. The magnetophoretic mobility and superparamagnetism of core-shell iron oxide nanoparticles with dual targeting and imaging functionality
  196. ATTEMPTS System: A Macromolecular Prodrug Strategy for Cancer Drug Delivery
  197. Alginate–Chitosan–PLGA Composite Microspheres Enabling Single-Shot Hepatitis B Vaccination
  198. Specific down regulation of 3T3-L1 adipocyte differentiation by cell-permeable antisense HIF1α-oligonucleotide
  199. Niosomal Delivery System for Macromolecular Drugs
  200. Synthetic Skin-Permeable Proteins Enabling Needleless Immunization
  201. Synthetic Skin-Permeable Proteins Enabling Needleless Immunization
  202. The artificial peroxidase activity of magnetic iron oxide nanoparticles and its application to glucose detection
  203. The ATTEMPTS delivery systems for macromolecular drugs
  204. A hybrid thermo-sensitive chitosan gel for sustained release of Meloxicam
  205. Glioma selectivity of magnetically targeted nanoparticles: A role of abnormal tumor hydrodynamics
  206. PEGylated synthetic surfactant vesicles (Niosomes): novel carriers for oligonucleotides
  207. Cationic liposomes modified with non-ionic surfactants as effective non-viral carrier for gene transfer
  208. Preparation and Characterization of Liposomes Encapsulating Chitosan Nanoparticles