All Stories

  1. Phospholipid complex-based microemulsion for treating concurrence of primary sclerosing cholangitis and inflammatory bowel disease via gut-liver crosstalk
  2. Inhalable Inclusion Cocrystal of Exocarpium Citri Grandis Volatile Oil for Treatment of Acute Lung Injury
  3. Biomimetically engineered plant-derived exosomes-like nanovesicles for rheumatoid arthritis therapy
  4. Ascorbic Acid-Derived Supramolecular Gels Induce Immunogenic Ferroptosis in Cancer Cells to Potentiate Tumor Immunotherapy
  5. Drug Repurposing with Topical Paclitaxel Delivery for Psoriasis Treatment Enabled by Plant-Inspired Molecular Assembly
  6. Ion-Gradient Driven Drug-Loading Liposomes for Codelivery of Shikonin/Regorafenib for Cancer Immunometabolic Therapy and Postoperative Intervention
  7. Nanohydroxyapatite-Stabilized Pickering-Emulsion-Incorporated Hydrogel Prevents Postoperative Osteosarcoma Recurrence and Promotes Bone Repair
  8. A bigel co-delivering highly hydrophilic and hydrophobic natural compounds for enhanced ulcerative colitis therapy
  9. Microalgae-carrying nanomedicine for bioadhesive drug delivery for treating chemotherapy-induced intestinal injury
  10. Targeting stem-property and vasculogenic mimicry for sensitizing paclitaxel therapy of triple-negative breast cancer by biomimetic codelivery
  11. In-situ trichosanthin-IL2/pectin dynamic hydrogel activates dendritic cells and reverses T cell exhaustion for post-operative cancer therapy
  12. An enhanced bioactive chitosan-modified microemulsion for mucosal healing of ulcerative colitis
  13. Natural product-integrated microneedle patch for rheumatoid arthritis treatment through anti-inflammation and angiogenesis suppression
  14. Co-delivery of TRAIL DNA and salinomycin for cancer therapy via enhanced apoptosis and cancer stemness inhibition
  15. Cellular vesicles-based “all-in-one” vaccine platform triggers mucosal immunity against respiratory viruses
  16. Intratumoral lactic acid neutralization strategy for boosting chemoimmunotherapy using liposomal sodium bicarbonate
  17. Carrier Polymer-Free Dissolvable Microneedles Enable Superhigh Drug Payload for Percutaneous Protein Delivery
  18. Uncovering key mechanisms and intervention therapies in aging skin
  19. Alginate/silk fibroin/Zn2+ composite microspheres for site-specific delivery for enhanced ulcerative colitis therapy
  20. Coronavirus spike protein-based vaccines. Vaccine delivery systems
  21. Aggregation-caused quenching to crystallization-induced emission transformation: hydration-induced luminescence in crystal curcumin with tunable thermochromism for in vivo tracking
  22. Immunometabolic rewiring in macrophages for periodontitis treatment via nanoquercetin-mediated leverage of glycolysis and OXPHOS
  23. Albumin is a reliable drug-delivering molecule: Highlighting points in cancer therapy
  24. Interactions between nanoparticles and lymphatic systems: Mechanisms and applications in drug delivery
  25. A Spatially Stable Crystal-Particle Gel to Trap Patchouli Oil for Efficient Colonic Drug Delivery
  26. Gastroretentive Raft Forming System for Enhancing Therapeutic Effect of Drug‐Loaded Hollow Mesoporous Silica on Gastric Ulcers
  27. Naturally sourced amphiphilic peptides as paclitaxel vehicles for breast cancer treatment
  28. Biomimetic nano-chelate diethyldithiocarbamate Cu/Fe for enhanced metalloimmunity and ferroptosis activation in glioma therapy
  29. Asiatic acid cyclodextrin inclusion micro-cocrystal for insoluble drug delivery and acute lung injury therapy enhancement
  30. Heparin-Conjugated ACE2-Bearing Extracellular Vesicles As Engineered Dual-Decoy for Combating the SARS-CoV-2 Omicron Variant via Pulmonary Delivery
  31. Blocking tumor-platelet crosstalk to prevent tumor metastasis via reprograming glycolysis using biomimetic membrane-hybridized liposomes
  32. Environment-responsive dendrobium polysaccharide hydrogel embedding manganese microsphere as a post-operative adjuvant to boost cascaded immune cycle against melanoma
  33. Tumor-Associated Macrophage Targeting of Nanomedicines in Cancer Therapy
  34. Epigenetic-based combination therapy and liposomal codelivery overcomes osimertinib-resistant NSCLC via repolarizing tumor-associated macrophages
  35. Rational design of oral delivery nanosystems for hypoglycemic peptides
  36. Pathologically catalyzed physical coating restores the intestinal barrier for inflammatory bowel disease therapy
  37. Author correction to “Neutralization of SARS-CoV-2 pseudovirus using ACE2-engineered extracellular vesicles” [Acta Pharmaceutica Sinica B 12 (2022) 1523–1533]
  38. Liposomal Resveratrol Alleviates Platelet Storage Lesion via Antioxidation and the Physical Buffering Effect
  39. Mitigation of Anti‐Drug Antibody Production for Augmenting Anticancer Efficacy of Therapeutic Protein via Co‐Injection of Nano‐Rapamycin
  40. Oral pectin/oligochitosan microspheres for colon-specific controlled release of quercetin to treat inflammatory bowel disease
  41. Correction to “Lactoferrin-Modified Gambogic Acid Liposomes for Colorectal Cancer Treatment”
  42. Cyclodextrin-Coordinated Liposome-in-Gel for Transcutaneous Quercetin Delivery for Psoriasis Treatment
  43. Lactoferrin-Modified Gambogic Acid Liposomes for Colorectal Cancer Treatment
  44. Targeting lactate metabolism and immune interaction in breast tumor via protease-triggered delivery
  45. Carbohydrate Strengthens the Immunotherapeutic Effect of Small-Molecule PD-L1 Inhibitors
  46. Cell penetrating peptides: Highlighting points in cancer therapy
  47. Regulating lactate-related immunometabolism and EMT reversal for colorectal cancer liver metastases using shikonin targeted delivery
  48. Toad venom bufadienolides and bufotoxins: An updated review
  49. Living Cells and Cell-Derived Vesicles: A Trojan Horse Technique for Brain Delivery
  50. Topical Delivery of Cell-Penetrating Peptide-Modified Human Growth Hormone for Enhanced Wound Healing
  51. Pharmaceutical liposomal delivery—specific considerations of innovation and challenges
  52. Recombinant cell-penetrating trichosanthin synergizes anti-PD-1 therapy in colorectal tumor
  53. Targeting glycolysis for cancer therapy using drug delivery systems
  54. Mannosylated engineered trichosanthin-legumain protein vaccine hydrogel for breast cancer immunotherapy
  55. Intracellular delivery of messenger RNA to macrophages with surfactant-derived lipid nanoparticles
  56. Localized delivery of nanomedicine and antibodies for combating COVID-19
  57. “Two-birds-one-stone” colon-targeted nanomedicine treats ulcerative colitis via remodeling immune microenvironment and anti-fibrosis
  58. Gold Nanocage-Based Photothermal Ablation Facilitates In Situ Vaccination for Melanoma Therapy
  59. Evaluation of Transdermal Transport and Concurrent Cutaneous Hydrolysis of Timolol Prodrug for the Treatment of Infantile Hemangiomas
  60. Nanoplateletsomes restrain metastatic tumor formation through decoy and active targeting in a preclinical mouse model
  61. Advances on Delivery of Cytotoxic Enzymes as Anticancer Agents
  62. Anti-alcoholism drug disulfiram for targeting glioma energy metabolism using BBB-penetrating delivery of fixed-dose combination
  63. Brain-targeting biomimetic nanoparticles for codelivery of celastrol and LY2157299 for reversing glioma immunosuppression
  64. Lipid Metabolism Regulation Based on Nanotechnology for Enhancement of Tumor Immunity
  65. A drug-free nanozyme for mitigating oxidative stress and inflammatory bowel disease
  66. Inhaled heparin polysaccharide nanodecoy against SARS-CoV-2 and variants
  67. Nanotherapeutic macrophage-based immunotherapy for the peritoneal carcinomatosis of lung cancer
  68. In Situ Pathologically Catalyzed Polydopamine Coating Enhances the Intestinal Barrier for Inflammatory Bowel Disease Therapy
  69. Remodeling immune microenvironment in periodontitis using resveratrol liposomes as an antibiotic-free therapeutic strategy
  70. Recombinant cancer nanovaccine for targeting tumor-associated macrophage and remodeling tumor microenvironment
  71. Disulfiram-loaded lactoferrin nanoparticles for treating inflammatory diseases
  72. Neutralization of SARS-CoV-2 pseudovirus using ACE2-engineered extracellular vesicles
  73. Remodeling “cold” tumor immune microenvironment via epigenetic-based therapy using targeted liposomes with in situ formed albumin corona
  74. Genetically-engineered “all-in-one” vaccine platform for cancer immunotherapy
  75. Teaching new tricks to old dogs: A review of drug repositioning of disulfiram for cancer nanomedicine
  76. Biomimetic camouflage delivery strategies for cancer therapy
  77. Magnetism-mediated targeting hyperthermia-immunotherapy in “cold” tumor with CSF1R inhibitor
  78. Biomimetic codelivery overcomes osimertinib-resistant NSCLC and brain metastasis via macrophage-mediated innate immunity
  79. Anti-PD-L1 mediating tumor-targeted codelivery of liposomal irinotecan/JQ1 for chemo-immunotherapy
  80. Metabolic modulation via mTOR pathway and anti-angiogenesis remodels tumor microenvironment using PD-L1-targeting codelivery
  81. Lactoferrin-mediated macrophage targeting delivery and patchouli alcohol-based therapeutic strategy for inflammatory bowel diseases
  82. Remodeling tumor immune microenvironment (TIME) for glioma therapy using multi-targeting liposomal codelivery
  83. Publisher Correction: ‘TRAIL-based gene delivery and therapeutic strategies’ and ‘Overview of recent advances in liposomal nanoparticle-based cancer immunotherapy’
  84. Nanotechnology-Based Histone Deacetylase Inhibitors for Cancer Therapy
  85. Dual‐Targeting to Cancer Cells and M2 Macrophages via Biomimetic Delivery of Mannosylated Albumin Nanoparticles for Drug‐Resistant Cancer Therapy
  86. Biomimetic metal-organic nanoparticles prepared with a 3D-printed microfluidic device as a novel formulation for disulfiram-based therapy against breast cancer
  87. A Trojan horse biomimetic delivery strategy using mesenchymal stem cells for PDT/PTT therapy against lung melanoma metastasis
  88. Macrophage-based nanotherapeutic strategies in ulcerative colitis
  89. Deformable liposomal codelivery of vorinostat and simvastatin promotes antitumor responses through remodeling tumor microenvironment
  90. BBB-penetrating codelivery liposomes treat brain metastasis of non-small cell lung cancer with EGFRT790M mutation
  91. Correction: A Trojan horse biomimetic delivery strategy using mesenchymal stem cells for PDT/PTT therapy against lung melanoma metastasis
  92. Introduction to biomimetic therapeutics
  93. Correction to Co-Delivery of Trichosanthin and Albendazole by Nano-Self-Assembly for Overcoming Tumor Multidrug-Resistance and Metastasis
  94. Advances on Tumor-Targeting Delivery of Cytotoxic Proteins
  95. Correction to Codelivery of Sorafenib and Curcumin by Directed Self-Assembled Nanoparticles Enhances Therapeutic Effect on Hepatocellular Carcinoma
  96. Recent progress in drug delivery
  97. TRAIL-based gene delivery and therapeutic strategies
  98. Menthol-modified BSA nanoparticles for glioma targeting therapy using an energy restriction strategy
  99. Trained Macrophage Bioreactor for Penetrating Delivery of Fused Antitumor Protein
  100. Transcutaneous Delivery of DNA/mRNA for Cancer Therapeutic Vaccination
  101. Reprogramming Tumor Immune Microenvironment (TIME) and Metabolism via Biomimetic Targeting Codelivery of Shikonin/JQ1
  102. Genetically-engineered protein prodrug-like nanoconjugates for tumor-targeting biomimetic delivery via a SHEATH strategy
  103. Targeting lipid metabolism to overcome EMT-associated drug resistance via integrin β3/FAK pathway and tumor-associated macrophage repolarization using legumain-activatable delivery
  104. The intra-brain distribution of brain targeting delivery systems
  105. Nano-Structural Effects on Gene Transfection: Large, Botryoid-Shaped Nanoparticles Enhance DNA Delivery via Macropinocytosis and Effective Dissociation
  106. Disulfiram Copper Nanoparticles Prepared with a Stabilized Metal Ion Ligand Complex Method for Treating Drug-Resistant Prostate Cancers
  107. Remodeling Tumor-Associated Macrophages and Neovascularization Overcomes EGFRT790M -Associated Drug Resistance by PD-L1 Nanobody-Mediated Codelivery
  108. The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis
  109. Natural Brain Penetration Enhancer-Modified Albumin Nanoparticles for Glioma Targeting Delivery
  110. Tat-functionalized Ag-Fe 3 O 4 nano-composites as tissue-penetrating vehicles for tumor magnetic targeting and drug delivery
  111. Antiglioma via regulating oxidative stress and remodeling tumor-associated macrophage using lactoferrin-mediated biomimetic codelivery of simvastatin/fenretinide
  112. Roles of Albumin-Binding Proteins in Cancer Progression and Biomimetic Targeted Drug Delivery
  113. A novel tumor-targeting treatment strategy uses energy restriction via co-delivery of albendazole and nanosilver
  114. Liposomal Codelivery of Doxorubicin and Andrographolide Inhibits Breast Cancer Growth and Metastasis
  115. Targeting death receptors for drug-resistant cancer therapy: Codelivery of pTRAIL and monensin using dual-targeting and stimuli-responsive self-assembling nanocomposites
  116. Macrophage-Membrane-Coated Nanoparticles for Tumor-Targeted Chemotherapy
  117. Improved Protein Toxin Delivery Based on ATTEMPTS Systems
  118. Dual-targeting biomimetic delivery for anti-glioma activityviaremodeling the tumor microenvironment and directing macrophage-mediated immunotherapy
  119. Biomimetic albumin-modified gold nanorods for photothermo-chemotherapy and macrophage polarization modulation
  120. Improved method for synthesis of low molecular weight protamine–siRNA conjugate
  121. Smart Cell-Penetrating Peptide-Based Techniques for Intracellular Delivery of Therapeutic Macromolecules
  122. Reprogramming Tumor-Associated Macrophages To Reverse EGFRT790M Resistance by Dual-Targeting Codelivery of Gefitinib/Vorinostat
  123. Cell-penetrating peptide-based non-invasive topical delivery systems
  124. Application of Monodisperse PEGs in Pharmaceutics: Monodisperse Polidocanols
  125. Co-Delivery of Trichosanthin and Albendazole by Nano-Self-Assembly for Overcoming Tumor Multidrug-Resistance and Metastasis
  126. Two-birds-one-stone delivery and therapeutic strategy for overcoming chemtherapy resistance
  127. Cancer nanobiotechnolgy
  128. Microneedle-Assisted, DC-Targeted Codelivery of pTRP-2 and Adjuvant of Paclitaxel for Transcutaneous Immunotherapy
  129. Identification of Epigallocatechin-3- Gallate as an Inhibitor of Phosphoglycerate Mutase 1
  130. Codelivery of dihydroartemisinin and doxorubicin in mannosylated liposomes for drug-resistant colon cancer therapy
  131. Tandem-multimeric F3-gelonin fusion toxins for enhanced anti-cancer activity for prostate cancer treatment
  132. Prodrug-Like, PEGylated Protein Toxin Trichosanthin for Reversal of Chemoresistance
  133. Intein-mediated site-specific synthesis of tumor-targeting protein delivery system: Turning PEG dilemma into prodrug-like feature
  134. Albumin Biomimetic Nanocorona Improves Tumor Targeting and Penetration for Synergistic Therapy of Metastatic Breast Cancer
  135. Poly-γ-glutamic acid-based GGT-targeting and surface camouflage strategy for improving cervical cancer gene therapy
  136. A mannosylated PEI–CPP hybrid for TRAIL gene targeting delivery for colorectal cancer therapy
  137. High-Yield Synthesis of Monomeric LMWP(CPP)-siRNA Covalent Conjugate for Effective Cytosolic Delivery of siRNA
  138. Glioma Dual-Targeting Nanohybrid Protein Toxin Constructed by Intein-Mediated Site-Specific Ligation for Multistage Booster Delivery
  139. Nanotechnology-based combination therapy for overcoming multidrug-resistant cancer
  140. Heparin-Regulated Prodrug-Type Macromolecular Theranostic Systems for Cancer Therapy
  141. Dual-Targeting Magnetic PLGA Nanoparticles for Codelivery of Paclitaxel and Curcumin for Brain Tumor Therapy
  142. Blood–Brain-Barrier-Penetrating Albumin Nanoparticles for Biomimetic Drug Delivery via Albumin-Binding Protein Pathways for Antiglioma Therapy
  143. Pharmacokinetics and Pharmacodynamics (PK/PD) of Bionanomaterials
  144. Nuclear-targeting TAT-PEG-Asp8-doxorubicin polymeric nanoassembly to overcome drug-resistant colon cancer
  145. Preparation and Characterization of Gelonin-Melittin Fusion Biotoxin for Synergistically Enhanced Anti-Tumor Activity
  146. Nose-to-brain delivery of macromolecules mediated by cell-penetrating peptides
  147. Intracellularly Acid-Switchable Multifunctional Micelles for Combinational Photo/Chemotherapy of the Drug-Resistant Tumor
  148. Gene Delivery: Fusogenic Reactive Oxygen Species Triggered Charge-Reversal Vector for Effective Gene Delivery (Adv. Mater. 9/2016)
  149. Hydrothermal Synthesis and Biocompatibility Study of Highly Crystalline Carbonated Hydroxyapatite Nanorods
  150. Fusogenic Reactive Oxygen Species Triggered Charge-Reversal Vector for Effective Gene Delivery
  151. Bioreducible Micelles with Endosomal Buffering and Multidrug Resistance-Reversing Function Enhance Anti-Tumor Efficacy of Doxorubicin
  152. Hydrothermal Synthesis and Biocompatibility Study of Highly Crystalline Carbonated Hydroxyapatite Nanorods
  153. Inhibition of metastasis and growth of breast cancer by pH-sensitive poly (β-amino ester) nanoparticles co-delivering two siRNA and paclitaxel
  154. Codelivery of Sorafenib and Curcumin by Directed Self-Assembled Nanoparticles Enhances Therapeutic Effect on Hepatocellular Carcinoma
  155. PTD-Modified ATTEMPTS for Enhanced Toxin-based Cancer Therapy: An In Vivo Proof-of-Concept Study
  156. Microneedle-assisted dendritic cell-targeted nanoparticles for transcutaneous DNA immunization
  157. Recent progress in microRNA delivery for cancer therapy by non-viral synthetic vectors
  158. Green synthesis of hyaluronic acid-based silver nanoparticles and their enhanced delivery to CD44+ cancer cells
  159. A Prodrug-type, MMP-2-targeting Nanoprobe for Tumor Detection and Imaging
  160. Molecular-Dynamics-Simulation-Driven Design of a Protease-Responsive Probe for In-Vivo Tumor Imaging
  161. Cell-Penetrating Apoptotic Peptide/p53 DNA Nanocomplex as Adjuvant Therapy for Drug-Resistant Breast Cancer
  162. Low-molecular-weight protamine-modified PLGA nanoparticles for overcoming drug-resistant breast cancer
  163. Editorial (Thematic Issue: “Cell-penetrating Peptides and Drug Delivery”)
  164. Cell-Penetrating Peptide-Mediated Topical Delivery of Biomacromolecular Drugs
  165. CPP-mediated Protein Delivery in a Noncovalent Form: Proof-of-Concept for Percutaneous and Intranasal Delivery
  166. Drug Delivery and Reversal of MDR
  167. Doxorubicin and Lapatinib Combination Nanomedicine for Treating Resistant Breast Cancer
  168. Protease-Activatable Hybrid Nanoprobe for Tumor Imaging
  169. Co-delivery of doxorubicin and RNA using pH-sensitive poly (β-amino ester) nanoparticles for reversal of multidrug resistance of breast cancer
  170. Epirubicin-Loaded Superparamagnetic Iron-Oxide Nanoparticles for Transdermal Delivery: Cancer Therapy by Circumventing the Skin Barrier
  171. Recombinant TAT-gelonin fusion toxin: Synthesis and characterization of heparin/protamine-regulated cell transduction
  172. The use of low molecular weight protamine chemical chimera to enhance monomeric insulin intestinal absorption
  173. Curb challenges of the “Trojan Horse” approach: Smart strategies in achieving effective yet safe cell-penetrating peptide-based drug delivery
  174. Co-delivery of Cell-permeable Chimeric Apoptosis AVPIR8Peptide/p53 DNA for Cocktail Therapy
  175. Ultrasound-mediated targeted microbubbles: a new vehicle for cancer therapy
  176. Overcoming oral insulin delivery barriers: application of cell penetrating peptide and silica-based nanoporous composites
  177. Magnetic Nanoparticles for Tumor Imaging and Therapy: A So-Called Theranostic System
  178. Pluronic L61 as a long-circulating modifier for enhanced liposomal delivery of cancer drugs
  179. Cell-penetrating albumin conjugates for enhanced doxorubicin delivery
  180. Template synthesis of PMAA@chitosan hollow nanorods for docetaxel delivery
  181. Cell-penetrating peptide-modified PLGA nanoparticles for enhanced nose-to-brain macromolecular delivery
  182. Magnetic Nanoparticles for MRI of Brain Tumors
  183. TAT-modified nanosilver for combating multidrug-resistant cancer
  184. Multifunctional drug delivery system for targeting tumor and its acidic microenvironment
  185. In vivo delivery of cell-permeable antisense hypoxia-inducible factor 1α oligonucleotide to adipose tissue reduces adiposity in obese mice
  186. Skin-permeable quaternary nanoparticles with layer-by-layer structure enabling improved gene delivery
  187. An injectable hybrid nanoparticle-in-oil-in-water submicron emulsion for improved delivery of poorly soluble drugs
  188. Low molecular weight protamine/insulin formulation with potential to attenuate protamine-masqueraded insulin allergy
  189. Downregulation of survivin expression and enhanced chemosensitivity of MCF-7 cells to adriamycin by PDMAE/survivin shRNA complex nanoparticles
  190. Polysorbate cationic synthetic vesicle for gene delivery
  191. An in situ-forming, solid lipid/PLGA hybrid implant for long-acting antipsychotics
  192. Co-administration of protein drugs with gold nanoparticles to enable percutaneous delivery
  193. The magnetophoretic mobility and superparamagnetism of core-shell iron oxide nanoparticles with dual targeting and imaging functionality
  194. ATTEMPTS System: A Macromolecular Prodrug Strategy for Cancer Drug Delivery
  195. Alginate–Chitosan–PLGA Composite Microspheres Enabling Single-Shot Hepatitis B Vaccination
  196. Specific down regulation of 3T3-L1 adipocyte differentiation by cell-permeable antisense HIF1α-oligonucleotide
  197. Niosomal Delivery System for Macromolecular Drugs
  198. Synthetic Skin-Permeable Proteins Enabling Needleless Immunization
  199. Synthetic Skin-Permeable Proteins Enabling Needleless Immunization
  200. The artificial peroxidase activity of magnetic iron oxide nanoparticles and its application to glucose detection
  201. The ATTEMPTS delivery systems for macromolecular drugs
  202. A hybrid thermo-sensitive chitosan gel for sustained release of Meloxicam
  203. Glioma selectivity of magnetically targeted nanoparticles: A role of abnormal tumor hydrodynamics
  204. PEGylated synthetic surfactant vesicles (Niosomes): novel carriers for oligonucleotides
  205. Cationic liposomes modified with non-ionic surfactants as effective non-viral carrier for gene transfer
  206. Preparation and Characterization of Liposomes Encapsulating Chitosan Nanoparticles