All Stories

  1. Molecular adaptation and clinical progression of Cryptococcus neoformans infection from the lungs to systemic dissemination
  2. Cryptococcus neoformans rewires the conserved Wee1-CDK checkpoint through two divergent kinases required for replication-stress tolerance and virulence
  3. Systematic profiling of WD40 proteins reveals Wcp1, a cyclophilin linking CO2/heat tolerance to acidic pH adaptation in Cryptococcus neoformans
  4. Systematic Profiling of Essential Fungal Transcription Factors Uncovers Ezt1 as a Central Pathobiological and Morphogenic Regulator in Cryptococcus neoformans
  5. Systematic histone mutagenesis reveals nucleosome-dependent maintenance of three-dimensional chromosome architecture and virulence in Cryptococcus neoformans
  6. Deciphering subcellular localization-dependent functions of Hog1 MAPK in Cryptococcus neoformans
  7. Fluorescent organelle markers in Cryptococcus neoformans : a versatile toolkit for live-cell subcellular localization
  8. Performance of FTIR-Based IR Biotyper for Identification and Strain Discrimination of Cryptococcus Species
  9. Fluorescent organelle markers in Cryptococcus neoformans: a versatile toolkit for live-cell subcellular localization
  10. The protein phosphatase 2C domain contributes to the pathobiological function of adenylyl cyclase in Cryptococcus neoformans
  11. Systems-level phosphoproteomics reveals conserved and subunit-specific STRIPAK signaling networks in Cryptococcus neoformans
  12. Deciphering subcellular localization-dependent functions of Hog1 MAPK in Cryptococcus neoformans
  13. The calcineurin pathway regulates extreme thermotolerance, cell membrane and wall integrity, antifungal resistance, and virulence in Candida auris
  14. Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans
  15. Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans
  16. Signaling pathways governing the pathobiological features and antifungal drug resistance of Candida auris
  17. Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans
  18. The calcineurin pathway regulates extreme thermotolerance, cell membrane and wall integrity, antifungal resistance, and virulence in Candida auris
  19. Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans
  20. Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans
  21. Sensing and responding to host-derived stress signals: lessons from fungal meningitis pathogen
  22. Unraveling the cryptic functions of mitogen-activated protein kinases Cpk2 and Mpk2 in Cryptococcus neoformans
  23. Casein kinase 2 complex: a central regulator of multiple pathobiological signaling pathways in Cryptococcus neoformans
  24. Sua5 catalyzing universal t 6 A tRNA modification is responsible for multifaceted functions of the KEOPS complex in Cryptococcus neoformans
  25. Deciphering the regulatory mechanisms of the cAMP/protein kinase A pathway and their roles in the pathogenicity of Candida auris
  26. The hybrid RAVE complex plays V-ATPase-dependent and -independent pathobiological roles in Cryptococcus neoformans
  27. Protein Kinase A Controls the Melanization of Candida auris through the Alteration of Cell Wall Components
  28. Adenylyl-Sulfate Kinase (Met14)-Dependent Cysteine and Methionine Biosynthesis Pathways Contribute Distinctively to Pathobiological Processes in Cryptococcus neoformans
  29. Dysregulating PHO Signaling via the CDK Machinery Differentially Impacts Energy Metabolism, Calcineurin Signaling, and Virulence in Cryptococcus neoformans
  30. Evaluation and Monitoring of the Natural Toxin Ptaquiloside in Bracken Fern, Meat, and Dairy Products
  31. Unraveling Capsule Biosynthesis and Signaling Networks in Cryptococcus neoformans
  32. Extension of O -Linked Mannosylation in the Golgi Apparatus Is Critical for Cell Wall Integrity Signaling and Interaction with Host Cells in Cryptococcus neoformans Pathogenesis
  33. Essential Roles of Ribonucleotide Reductases under DNA Damage and Replication Stresses in Cryptococcus neoformans
  34. Role of the Heme Activator Protein Complex in the Sexual Development of Cryptococcus neoformans
  35. Rare β-Resorcylic Acid Derivatives from a Halophyte-Associated Fungus Colletotrichum gloeosporioides JS0419 and Their Antifungal Activities
  36. Pathogens infecting the central nervous system
  37. Atypical Bacilliredoxin AbxC Plays a Role in Responding to Oxidative Stress in Radiation-Resistant Bacterium Deinococcus radiodurans
  38. Zinc-binding domain mediates pleiotropic functions of Yvh1 in Cryptococcus neoformans
  39. Fungal brain infection modelled in a human-neurovascular-unit-on-a-chip with a functional blood–brain barrier
  40. Transcriptomic and Metabolomic Analysis Revealed Roles of Yck2 in Carbon Metabolism and Morphogenesis of Candida albicans
  41. Erratum: Microbe Profile: Cryptococcus neoformans species complex
  42. A Signature-Tagged Mutagenesis (STM)-based murine-infectivity assay for Cryptococcus neoformans
  43. Corrigendum: Sho1 and Msb2 Play Complementary but Distinct Roles in Stress Responses, Sexual Differentiation, and Pathogenicity of Cryptococcus neoformans
  44. Microbe Profile: Cryptococcus neoformans species complex
  45. Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans
  46. Core N-Glycan Structures Are Critical for the Pathogenicity of Cryptococcus neoformans by Modulating Host Cell Death
  47. Fungal kinases and transcription factors regulating brain infection in Cryptococcus neoformans
  48. Antioxidant Activities of an Exopolysaccharide (DeinoPol) Produced by the Extreme Radiation-Resistant Bacterium Deinococcus radiodurans
  49. Corrigendum to: Molecular Characterization of Adenylyl Cyclase Complex Proteins Using Versatile Protein-Tagging Plasmid Systems in Cryptococcus neoformans
  50. Regulatory Mechanism of the Atypical AP-1-Like Transcription Factor Yap1 in Cryptococcus neoformans
  51. Structural analysis of fungal pathogenicity-related casein kinase α subunit, Cka1, in the human fungal pathogen Cryptococcus neoformans
  52. Unraveling Melanin Biosynthesis and Signaling Networks in Cryptococcus neoformans
  53. Biosynthesis of Nonimmunosuppressive FK506 Analogues with Antifungal Activity
  54. The TOR Pathway Plays Pleiotropic Roles in Growth and Stress Responses of the Fungal Pathogen Cryptococcus neoformans
  55. Antioxidant, Anti-inflammatory, and Neuroprotective Effects of Novel Vinyl Sulfonate Compounds as Nrf2 Activator
  56. Nutrient and Stress Sensing in Pathogenic Yeasts
  57. Rad53- and Chk1-Dependent DNA Damage Response Pathways Cooperatively Promote Fungal Pathogenesis and Modulate Antifungal Drug Susceptibility
  58. Sho1 and Msb2 Play Complementary but Distinct Roles in Stress Responses, Sexual Differentiation, and Pathogenicity of Cryptococcus neoformans
  59. In Vitro and In Vivo Assessment of FK506 Analogs as Novel Antifungal Drug Candidates
  60. Genetic Manipulation ofCryptococcus neoformans
  61. Evolutionarily Conserved and Divergent Roles of Unfolded Protein Response (UPR) in the Pathogenic Cryptococcus Species Complex
  62. Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson’s disease therapy
  63. The novel microtubule-associated CAP-glycine protein Cgp1 governs growth, differentiation, and virulence of Cryptococcus neoformans
  64. Crystal structure of inositol 1,3,4,5,6-pentakisphosphate 2-kinase from Cryptococcus neoformans
  65. Glucosamine stimulates pheromone-independent dimorphic transition in Cryptococcus neoformans by promoting Crz1 nuclear translocation
  66. Microbial radiation-resistance mechanisms
  67. A novel bZIP protein, Gsb1, is required for oxidative stress response, mating, and virulence in the human pathogen Cryptococcus neoformans
  68. The water channel protein aquaporin 1 regulates cellular metabolism and competitive fitness in a global fungal pathogen C ryptococcus neoformans
  69. Molecular Characterization of Adenylyl Cyclase Complex Proteins Using Versatile Protein-Tagging Plasmid Systems in Cryptococcus neoformans
  70. Pho4 Is Essential for Dissemination of Cryptococcus neoformans to the Host Brain by Promoting Phosphate Uptake and Growth at Alkaline pH
  71. Unraveling Fungal Radiation Resistance Regulatory Networks through the Genome-Wide Transcriptome and Genetic Analyses ofCryptococcus neoformans
  72. Rewiring of Signaling Networks Modulating Thermotolerance in the Human Pathogen Cryptococcus neoformans
  73. Systemic Approach to Virulence Gene Network Analysis for Gaining New Insight into Cryptococcal Virulence
  74. Metal Chelation as a Powerful Strategy to Probe Cellular Circuitry Governing Fungal Drug Resistance and Morphogenesis
  75. Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans
  76. Unique roles of the unfolded protein response pathway in fungal development and differentiation
  77. Intron retention-dependent gene regulation in Cryptococcus neoformans
  78. Dual action antifungal small molecule modulates multidrug efflux and TOR signaling
  79. Major Sensing Proteins in Pathogenic Fungi: The Hybrid Histidine Kinase Family
  80. Fungal physiology: Red light plugs into MAPK pathway
  81. Relative Contributions of Prenylation and Postprenylation Processing in Cryptococcus neoformans Pathogenesis
  82. Screening, Synthesis, and In Vitro Evaluation of Vinyl Sulfones as Inhibitors of Complement-Dependent Cytotoxicity in Neuromyelitis Optica
  83. An Antifungal Combination Matrix Identifies a Rich Pool of Adjuvant Molecules that Enhance Drug Activity against Diverse Fungal Pathogens
  84. A Phenylpropanoid Glycoside as a Calcineurin Inhibitor Isolated from Magnolia obovata Thunb.
  85. Exploiting Fungal Virulence-Regulating Transcription Factors As Novel Antifungal Drug Targets
  86. Systematic functional profiling of transcription factor networks in Cryptococcus neoformans
  87. Network-assisted genetic dissection of pathogenicity and drug resistance in the opportunistic human pathogenic fungus Cryptococcus neoformans
  88. Unraveling the Novel Structure and Biosynthetic Pathway ofO-Linked Glycans in the Golgi Apparatus of the Human Pathogenic YeastCryptococcus neoformans
  89. Inhibition of the Calcineurin Pathway by Two Tannins, Chebulagic Acid and Chebulanin, Isolated from Harrisonia abyssinica Oliv.
  90. 9-O-butyl-13-(4-isopropylbenzyl)berberine, KR-72, Is a Potent Antifungal Agent That Inhibits the Growth of Cryptococcus neoformans by Regulating Gene Expression
  91. Cryptococcus neoformans and Cryptococcus gattii, the Etiologic Agents of Cryptococcosis
  92. A Ferroxidase, Cfo1, Regulates Diverse Environmental Stress Responses of Cryptococcus neoformans through the HOG Pathway
  93. Analysis of the Genome and Transcriptome of Cryptococcus neoformans var. grubii Reveals Complex RNA Expression and Microevolution Leading to Virulence Attenuation
  94. Distinct and Redundant Roles of Protein Tyrosine Phosphatases Ptp1 and Ptp2 in Governing the Differentiation and Pathogenicity of Cryptococcus neoformans
  95. A Nudix Hydrolase Protein, Ysa1, Regulates Oxidative Stress Response and Antifungal Drug Susceptibility in Cryptococcus neoformans
  96. A Novel Radiation-Resistant Strain of Filobasidium sp. Isolated from the West Sea of Korea
  97. The unfolded protein response (UPR) pathway inCryptococcus
  98. Unraveling unique structure and biosynthesis pathway ofN-linked glycans in human fungal pathogenCryptococcus neoformansby glycomics analysis.
  99. Sulphiredoxin plays peroxiredoxin-dependent and -independent roles via the HOG signalling pathway inCryptococcus neoformansand contributes to fungal virulence
  100. Stress Signaling Pathways for the Pathogenicity of Cryptococcus
  101. Global transcriptome analysis of eukaryotic genes affected by gromwell extract
  102. Essential Roles of the Kar2/BiP Molecular Chaperone Downstream of the UPR Pathway in Cryptococcus neoformans
  103. Msi1-Like (MSIL) Proteins in Fungi
  104. Pleiotropic Roles of the Msi1-Like Protein Msl1 in Cryptococcus neoformans
  105. Unraveling Unique Structure and Biosynthesis Pathway ofN-Linked Glycans in Human Fungal PathogenCryptococcus neoformansby Glycomics Analysis
  106. Two cation transporters Ena1 and Nha1 cooperatively modulate ion homeostasis, antifungal drug resistance, and virulence of Cryptococcus neoformans via the HOG pathway
  107. Targeted Gene Disruption in Cryptococcus neoformans Using Double-Joint PCR with Split Dominant Selectable Markers
  108. A Flucytosine-Responsive Mbp1/Swi4-Like Protein, Mbs1, Plays Pleiotropic Roles in Antifungal Drug Resistance, Stress Response, and Virulence of Cryptococcus neoformans
  109. Unique Evolution of the UPR Pathway with a Novel bZIP Transcription Factor, Hxl1, for Controlling Pathogenicity of Cryptococcus neoformans
  110. Cryptococcal Titan Cell Formation Is Regulated by G-Protein Signaling in Response to Multiple Stimuli
  111. Multiple Roles of Ypd1 Phosphotransfer Protein in Viability, Stress Response, and Virulence Factor Regulation in Cryptococcus neoformans
  112. Hrk1 Plays Both Hog1-Dependent and -Independent Roles in Controlling Stress Response and Antifungal Drug Resistance in Cryptococcus neoformans
  113. Ste50 adaptor protein governs sexual differentiation of Cryptococcus neoformans via the pheromone-response MAPK signaling pathway
  114. Characterizing the role of RNA silencing components in Cryptococcus neoformans
  115. Comparative Transcriptome Analysis of the CO2 Sensing Pathway Via Differential Expression of Carbonic Anhydrase in Cryptococcus neoformans
  116. Corrigendum to “An efficient gene-disruption method in Cryptococcus neoformans by double-joint PCR with NAT-split markers” [Biochem. Biophys. Res. Commun. 390 (2009) 983–988]
  117. The conserved and divergent roles of carbonic anhydrases in the filamentous fungiAspergillus fumigatusandAspergillus nidulans
  118. Comparative Transcriptome Analysis Reveals Novel Roles of the Ras and Cyclic AMP Signaling Pathways in Environmental Stress Response and Antifungal Drug Sensitivity in Cryptococcus neoformans
  119. Functional Characterization of cAMP-Regulated Gene,CAR1, inCryptococcus neoformans
  120. An efficient gene-disruption method in Cryptococcus neoformans by double-joint PCR with NAT-split markers
  121. The conserved and divergent roles of carbonic anhydrases in the filamentous fungi Aspergillus fumigatus and Aspergillus nidulans
  122. Remodeling of Global Transcription Patterns of Cryptococcus neoformans Genes Mediated by the Stress-Activated HOG Signaling Pathways
  123. The Stress-Activated Signaling (SAS) Pathways of a Human Fungal Pathogen,Cryptococcus neoformans
  124. Master and Commander in Fungal Pathogens: the Two-Component System and the HOG Signaling Pathway
  125. Genome-Wide Transcriptional Profiling of the Cyclic AMP-Dependent Signaling Pathway during Morphogenic Transitions of Candida albicans
  126. Ssk2 Mitogen-Activated Protein Kinase Kinase Kinase Governs Divergent Patterns of the Stress-Activated Hog1 Signaling Pathway in Cryptococcus neoformans
  127. State of differentiation defines buccal epithelial cell affinity for cross-linking to Candida albicans Hwp1
  128. Sensing the environment: lessons from fungi
  129. CO2 sensing in fungi and beyond
  130. A Unique Fungal Two-Component System Regulates Stress Responses, Drug Sensitivity, Sexual Development, and Virulence of Cryptococcus neoformans
  131. Calcineurin, Mpk1 and Hog1 MAPK pathways independently control fludioxonil antifungal sensitivity in Cryptococcus neoformans
  132. G Protein-coupled Receptor Gpr4 Senses Amino Acids and Activates the cAMP-PKA Pathway in Cryptococcus neoformans
  133. Pde1 Phosphodiesterase Modulates Cyclic AMP Levels through a Protein Kinase A-Mediated Negative Feedback Loop in Cryptococcus neoformans
  134. Carbonic Anhydrase and CO2 Sensing during Cryptococcus neoformans Growth, Differentiation, and Virulence
  135. Deciphering the Model Pathogenic Fungus Cryptococcus Neoformans
  136. Specialization of the HOG Pathway and Its Impact on Differentiation and Virulence of Cryptococcus neoformans
  137. Adenylyl Cyclase-Associated Protein Aca1 Regulates Virulence and Differentiation of Cryptococcus neoformans via the Cyclic AMP-Protein Kinase A Cascade
  138. Expression of Transglutaminase Substrate Activity onCandida albicansGerm Tubes through a Coiled, Disulfide-bonded N-terminal Domain of Hwp1 Requires C-terminal Glycosylphosphatidylinositol Modification
  139. Increased high-affinity phosphodiesterase PDE2 gene expression in germ tubes counteracts CAP1-dependent synthesis of cyclic AMP, limits hypha production and promotes virulence of Candida albicans
  140. CAP1, an Adenylate Cyclase-Associated Protein Gene, Regulates Bud-Hypha Transitions, Filamentous Growth, and Cyclic AMP Levels and Is Required for Virulence of Candida albicans