All Stories

  1. Systematic profiling of WD40 proteins reveals Wcp1, a cyclophilin linking CO2/heat tolerance to acidic pH adaptation in Cryptococcus neoformans
  2. Systematic Profiling of Essential Fungal Transcription Factors Uncovers Ezt1 as a Central Pathobiological and Morphogenic Regulator in Cryptococcus neoformans
  3. Systematic histone mutagenesis reveals nucleosome-dependent maintenance of three-dimensional chromosome architecture and virulence in Cryptococcus neoformans
  4. Deciphering subcellular localization-dependent functions of Hog1 MAPK in Cryptococcus neoformans
  5. Fluorescent organelle markers in Cryptococcus neoformans : a versatile toolkit for live-cell subcellular localization
  6. Performance of FTIR-Based IR Biotyper for Identification and Strain Discrimination of Cryptococcus Species
  7. Fluorescent organelle markers in Cryptococcus neoformans: a versatile toolkit for live-cell subcellular localization
  8. The protein phosphatase 2C domain contributes to the pathobiological function of adenylyl cyclase in Cryptococcus neoformans
  9. Systems-level phosphoproteomics reveals conserved and subunit-specific STRIPAK signaling networks in Cryptococcus neoformans
  10. Deciphering subcellular localization-dependent functions of Hog1 MAPK in Cryptococcus neoformans
  11. The calcineurin pathway regulates extreme thermotolerance, cell membrane and wall integrity, antifungal resistance, and virulence in Candida auris
  12. Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans
  13. Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans
  14. Signaling pathways governing the pathobiological features and antifungal drug resistance of Candida auris
  15. Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans
  16. The calcineurin pathway regulates extreme thermotolerance, cell membrane and wall integrity, antifungal resistance, and virulence in Candida auris
  17. Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans
  18. Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans
  19. Sensing and responding to host-derived stress signals: lessons from fungal meningitis pathogen
  20. Unraveling the cryptic functions of mitogen-activated protein kinases Cpk2 and Mpk2 in Cryptococcus neoformans
  21. Casein kinase 2 complex: a central regulator of multiple pathobiological signaling pathways in Cryptococcus neoformans
  22. Sua5 catalyzing universal t 6 A tRNA modification is responsible for multifaceted functions of the KEOPS complex in Cryptococcus neoformans
  23. Deciphering the regulatory mechanisms of the cAMP/protein kinase A pathway and their roles in the pathogenicity of Candida auris
  24. The hybrid RAVE complex plays V-ATPase-dependent and -independent pathobiological roles in Cryptococcus neoformans
  25. Protein Kinase A Controls the Melanization of Candida auris through the Alteration of Cell Wall Components
  26. Adenylyl-Sulfate Kinase (Met14)-Dependent Cysteine and Methionine Biosynthesis Pathways Contribute Distinctively to Pathobiological Processes in Cryptococcus neoformans
  27. Dysregulating PHO Signaling via the CDK Machinery Differentially Impacts Energy Metabolism, Calcineurin Signaling, and Virulence in Cryptococcus neoformans
  28. Evaluation and Monitoring of the Natural Toxin Ptaquiloside in Bracken Fern, Meat, and Dairy Products
  29. Unraveling Capsule Biosynthesis and Signaling Networks in Cryptococcus neoformans
  30. Extension of O -Linked Mannosylation in the Golgi Apparatus Is Critical for Cell Wall Integrity Signaling and Interaction with Host Cells in Cryptococcus neoformans Pathogenesis
  31. Essential Roles of Ribonucleotide Reductases under DNA Damage and Replication Stresses in Cryptococcus neoformans
  32. Role of the Heme Activator Protein Complex in the Sexual Development of Cryptococcus neoformans
  33. Rare β-Resorcylic Acid Derivatives from a Halophyte-Associated Fungus Colletotrichum gloeosporioides JS0419 and Their Antifungal Activities
  34. Pathogens infecting the central nervous system
  35. Atypical Bacilliredoxin AbxC Plays a Role in Responding to Oxidative Stress in Radiation-Resistant Bacterium Deinococcus radiodurans
  36. Zinc-binding domain mediates pleiotropic functions of Yvh1 in Cryptococcus neoformans
  37. Fungal brain infection modelled in a human-neurovascular-unit-on-a-chip with a functional blood–brain barrier
  38. Transcriptomic and Metabolomic Analysis Revealed Roles of Yck2 in Carbon Metabolism and Morphogenesis of Candida albicans
  39. Erratum: Microbe Profile: Cryptococcus neoformans species complex
  40. A Signature-Tagged Mutagenesis (STM)-based murine-infectivity assay for Cryptococcus neoformans
  41. Corrigendum: Sho1 and Msb2 Play Complementary but Distinct Roles in Stress Responses, Sexual Differentiation, and Pathogenicity of Cryptococcus neoformans
  42. Microbe Profile: Cryptococcus neoformans species complex
  43. Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans
  44. Core N-Glycan Structures Are Critical for the Pathogenicity of Cryptococcus neoformans by Modulating Host Cell Death
  45. Fungal kinases and transcription factors regulating brain infection in Cryptococcus neoformans
  46. Antioxidant Activities of an Exopolysaccharide (DeinoPol) Produced by the Extreme Radiation-Resistant Bacterium Deinococcus radiodurans
  47. Corrigendum to: Molecular Characterization of Adenylyl Cyclase Complex Proteins Using Versatile Protein-Tagging Plasmid Systems in Cryptococcus neoformans
  48. Regulatory Mechanism of the Atypical AP-1-Like Transcription Factor Yap1 in Cryptococcus neoformans
  49. Structural analysis of fungal pathogenicity-related casein kinase α subunit, Cka1, in the human fungal pathogen Cryptococcus neoformans
  50. Unraveling Melanin Biosynthesis and Signaling Networks in Cryptococcus neoformans
  51. Biosynthesis of Nonimmunosuppressive FK506 Analogues with Antifungal Activity
  52. The TOR Pathway Plays Pleiotropic Roles in Growth and Stress Responses of the Fungal Pathogen Cryptococcus neoformans
  53. Antioxidant, Anti-inflammatory, and Neuroprotective Effects of Novel Vinyl Sulfonate Compounds as Nrf2 Activator
  54. Nutrient and Stress Sensing in Pathogenic Yeasts
  55. Rad53- and Chk1-Dependent DNA Damage Response Pathways Cooperatively Promote Fungal Pathogenesis and Modulate Antifungal Drug Susceptibility
  56. Sho1 and Msb2 Play Complementary but Distinct Roles in Stress Responses, Sexual Differentiation, and Pathogenicity of Cryptococcus neoformans
  57. In Vitro and In Vivo Assessment of FK506 Analogs as Novel Antifungal Drug Candidates
  58. Genetic Manipulation ofCryptococcus neoformans
  59. Evolutionarily Conserved and Divergent Roles of Unfolded Protein Response (UPR) in the Pathogenic Cryptococcus Species Complex
  60. Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson’s disease therapy
  61. The novel microtubule-associated CAP-glycine protein Cgp1 governs growth, differentiation, and virulence of Cryptococcus neoformans
  62. Crystal structure of inositol 1,3,4,5,6-pentakisphosphate 2-kinase from Cryptococcus neoformans
  63. Glucosamine stimulates pheromone-independent dimorphic transition in Cryptococcus neoformans by promoting Crz1 nuclear translocation
  64. Microbial radiation-resistance mechanisms
  65. A novel bZIP protein, Gsb1, is required for oxidative stress response, mating, and virulence in the human pathogen Cryptococcus neoformans
  66. The water channel protein aquaporin 1 regulates cellular metabolism and competitive fitness in a global fungal pathogen C ryptococcus neoformans
  67. Molecular Characterization of Adenylyl Cyclase Complex Proteins Using Versatile Protein-Tagging Plasmid Systems in Cryptococcus neoformans
  68. Pho4 Is Essential for Dissemination of Cryptococcus neoformans to the Host Brain by Promoting Phosphate Uptake and Growth at Alkaline pH
  69. Unraveling Fungal Radiation Resistance Regulatory Networks through the Genome-Wide Transcriptome and Genetic Analyses ofCryptococcus neoformans
  70. Rewiring of Signaling Networks Modulating Thermotolerance in the Human Pathogen Cryptococcus neoformans
  71. Systemic Approach to Virulence Gene Network Analysis for Gaining New Insight into Cryptococcal Virulence
  72. Metal Chelation as a Powerful Strategy to Probe Cellular Circuitry Governing Fungal Drug Resistance and Morphogenesis
  73. Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans
  74. Unique roles of the unfolded protein response pathway in fungal development and differentiation
  75. Intron retention-dependent gene regulation in Cryptococcus neoformans
  76. Dual action antifungal small molecule modulates multidrug efflux and TOR signaling
  77. Major Sensing Proteins in Pathogenic Fungi: The Hybrid Histidine Kinase Family
  78. Fungal physiology: Red light plugs into MAPK pathway
  79. Relative Contributions of Prenylation and Postprenylation Processing in Cryptococcus neoformans Pathogenesis
  80. Screening, Synthesis, and In Vitro Evaluation of Vinyl Sulfones as Inhibitors of Complement-Dependent Cytotoxicity in Neuromyelitis Optica
  81. An Antifungal Combination Matrix Identifies a Rich Pool of Adjuvant Molecules that Enhance Drug Activity against Diverse Fungal Pathogens
  82. A Phenylpropanoid Glycoside as a Calcineurin Inhibitor Isolated from Magnolia obovata Thunb.
  83. Exploiting Fungal Virulence-Regulating Transcription Factors As Novel Antifungal Drug Targets
  84. Systematic functional profiling of transcription factor networks in Cryptococcus neoformans
  85. Network-assisted genetic dissection of pathogenicity and drug resistance in the opportunistic human pathogenic fungus Cryptococcus neoformans
  86. Unraveling the Novel Structure and Biosynthetic Pathway ofO-Linked Glycans in the Golgi Apparatus of the Human Pathogenic YeastCryptococcus neoformans
  87. Inhibition of the Calcineurin Pathway by Two Tannins, Chebulagic Acid and Chebulanin, Isolated from Harrisonia abyssinica Oliv.
  88. 9-O-butyl-13-(4-isopropylbenzyl)berberine, KR-72, Is a Potent Antifungal Agent That Inhibits the Growth of Cryptococcus neoformans by Regulating Gene Expression
  89. Cryptococcus neoformans and Cryptococcus gattii, the Etiologic Agents of Cryptococcosis
  90. A Ferroxidase, Cfo1, Regulates Diverse Environmental Stress Responses of Cryptococcus neoformans through the HOG Pathway
  91. Analysis of the Genome and Transcriptome of Cryptococcus neoformans var. grubii Reveals Complex RNA Expression and Microevolution Leading to Virulence Attenuation
  92. Distinct and Redundant Roles of Protein Tyrosine Phosphatases Ptp1 and Ptp2 in Governing the Differentiation and Pathogenicity of Cryptococcus neoformans
  93. A Nudix Hydrolase Protein, Ysa1, Regulates Oxidative Stress Response and Antifungal Drug Susceptibility in Cryptococcus neoformans
  94. A Novel Radiation-Resistant Strain of Filobasidium sp. Isolated from the West Sea of Korea
  95. The unfolded protein response (UPR) pathway inCryptococcus
  96. Unraveling unique structure and biosynthesis pathway ofN-linked glycans in human fungal pathogenCryptococcus neoformansby glycomics analysis.
  97. Sulphiredoxin plays peroxiredoxin-dependent and -independent roles via the HOG signalling pathway inCryptococcus neoformansand contributes to fungal virulence
  98. Stress Signaling Pathways for the Pathogenicity of Cryptococcus
  99. Global transcriptome analysis of eukaryotic genes affected by gromwell extract
  100. Essential Roles of the Kar2/BiP Molecular Chaperone Downstream of the UPR Pathway in Cryptococcus neoformans
  101. Msi1-Like (MSIL) Proteins in Fungi
  102. Pleiotropic Roles of the Msi1-Like Protein Msl1 in Cryptococcus neoformans
  103. Unraveling Unique Structure and Biosynthesis Pathway ofN-Linked Glycans in Human Fungal PathogenCryptococcus neoformansby Glycomics Analysis
  104. Two cation transporters Ena1 and Nha1 cooperatively modulate ion homeostasis, antifungal drug resistance, and virulence of Cryptococcus neoformans via the HOG pathway
  105. Targeted Gene Disruption in Cryptococcus neoformans Using Double-Joint PCR with Split Dominant Selectable Markers
  106. A Flucytosine-Responsive Mbp1/Swi4-Like Protein, Mbs1, Plays Pleiotropic Roles in Antifungal Drug Resistance, Stress Response, and Virulence of Cryptococcus neoformans
  107. Unique Evolution of the UPR Pathway with a Novel bZIP Transcription Factor, Hxl1, for Controlling Pathogenicity of Cryptococcus neoformans
  108. Cryptococcal Titan Cell Formation Is Regulated by G-Protein Signaling in Response to Multiple Stimuli
  109. Multiple Roles of Ypd1 Phosphotransfer Protein in Viability, Stress Response, and Virulence Factor Regulation in Cryptococcus neoformans
  110. Hrk1 Plays Both Hog1-Dependent and -Independent Roles in Controlling Stress Response and Antifungal Drug Resistance in Cryptococcus neoformans
  111. Ste50 adaptor protein governs sexual differentiation of Cryptococcus neoformans via the pheromone-response MAPK signaling pathway
  112. Characterizing the role of RNA silencing components in Cryptococcus neoformans
  113. Comparative Transcriptome Analysis of the CO2 Sensing Pathway Via Differential Expression of Carbonic Anhydrase in Cryptococcus neoformans
  114. Corrigendum to “An efficient gene-disruption method in Cryptococcus neoformans by double-joint PCR with NAT-split markers” [Biochem. Biophys. Res. Commun. 390 (2009) 983–988]
  115. The conserved and divergent roles of carbonic anhydrases in the filamentous fungiAspergillus fumigatusandAspergillus nidulans
  116. Comparative Transcriptome Analysis Reveals Novel Roles of the Ras and Cyclic AMP Signaling Pathways in Environmental Stress Response and Antifungal Drug Sensitivity in Cryptococcus neoformans
  117. Functional Characterization of cAMP-Regulated Gene,CAR1, inCryptococcus neoformans
  118. An efficient gene-disruption method in Cryptococcus neoformans by double-joint PCR with NAT-split markers
  119. The conserved and divergent roles of carbonic anhydrases in the filamentous fungi Aspergillus fumigatus and Aspergillus nidulans
  120. Remodeling of Global Transcription Patterns of Cryptococcus neoformans Genes Mediated by the Stress-Activated HOG Signaling Pathways
  121. The Stress-Activated Signaling (SAS) Pathways of a Human Fungal Pathogen,Cryptococcus neoformans
  122. Master and Commander in Fungal Pathogens: the Two-Component System and the HOG Signaling Pathway
  123. Genome-Wide Transcriptional Profiling of the Cyclic AMP-Dependent Signaling Pathway during Morphogenic Transitions of Candida albicans
  124. Ssk2 Mitogen-Activated Protein Kinase Kinase Kinase Governs Divergent Patterns of the Stress-Activated Hog1 Signaling Pathway in Cryptococcus neoformans
  125. State of differentiation defines buccal epithelial cell affinity for cross-linking to Candida albicans Hwp1
  126. Sensing the environment: lessons from fungi
  127. CO2 sensing in fungi and beyond
  128. A Unique Fungal Two-Component System Regulates Stress Responses, Drug Sensitivity, Sexual Development, and Virulence of Cryptococcus neoformans
  129. Calcineurin, Mpk1 and Hog1 MAPK pathways independently control fludioxonil antifungal sensitivity in Cryptococcus neoformans
  130. G Protein-coupled Receptor Gpr4 Senses Amino Acids and Activates the cAMP-PKA Pathway in Cryptococcus neoformans
  131. Pde1 Phosphodiesterase Modulates Cyclic AMP Levels through a Protein Kinase A-Mediated Negative Feedback Loop in Cryptococcus neoformans
  132. Carbonic Anhydrase and CO2 Sensing during Cryptococcus neoformans Growth, Differentiation, and Virulence
  133. Deciphering the Model Pathogenic Fungus Cryptococcus Neoformans
  134. Specialization of the HOG Pathway and Its Impact on Differentiation and Virulence of Cryptococcus neoformans
  135. Adenylyl Cyclase-Associated Protein Aca1 Regulates Virulence and Differentiation of Cryptococcus neoformans via the Cyclic AMP-Protein Kinase A Cascade
  136. Expression of Transglutaminase Substrate Activity onCandida albicansGerm Tubes through a Coiled, Disulfide-bonded N-terminal Domain of Hwp1 Requires C-terminal Glycosylphosphatidylinositol Modification
  137. Increased high-affinity phosphodiesterase PDE2 gene expression in germ tubes counteracts CAP1-dependent synthesis of cyclic AMP, limits hypha production and promotes virulence of Candida albicans
  138. CAP1, an Adenylate Cyclase-Associated Protein Gene, Regulates Bud-Hypha Transitions, Filamentous Growth, and Cyclic AMP Levels and Is Required for Virulence of Candida albicans