All Stories

  1. Molecular adaptation and clinical progression of Cryptococcus neoformans infection from the lungs to systemic dissemination
  2. The protein phosphatase 2A catalytic subunit Pph22 partners with Tap42 and Rrd2 to control viability and virulence in Cryptococcus neoformans
  3. Distinct STRIPAK subunits drive conserved and subunit-specific signaling programs in Cryptococcus neoformans
  4. Cryptococcus neoformans rewires the conserved Wee1-CDK checkpoint through two divergent kinases required for replication-stress tolerance and virulence
  5. Systematic profiling of WD40 proteins reveals Wcp1, a cyclophilin linking CO2/heat tolerance to acidic pH adaptation in Cryptococcus neoformans
  6. Systematic Profiling of Essential Fungal Transcription Factors Uncovers Ezt1 as a Central Pathobiological and Morphogenic Regulator in Cryptococcus neoformans
  7. Systematic histone mutagenesis reveals nucleosome-dependent maintenance of three-dimensional chromosome architecture and virulence in Cryptococcus neoformans
  8. Deciphering subcellular localization-dependent functions of Hog1 MAPK in Cryptococcus neoformans
  9. Fluorescent organelle markers in Cryptococcus neoformans : a versatile toolkit for live-cell subcellular localization
  10. Performance of FTIR-Based IR Biotyper for Identification and Strain Discrimination of Cryptococcus Species
  11. Fluorescent organelle markers in Cryptococcus neoformans: a versatile toolkit for live-cell subcellular localization
  12. The protein phosphatase 2C domain contributes to the pathobiological function of adenylyl cyclase in Cryptococcus neoformans
  13. Systems-level phosphoproteomics reveals conserved and subunit-specific STRIPAK signaling networks in Cryptococcus neoformans
  14. Conserved and rewired MAPK networks in human fungal pathogens
  15. Deciphering subcellular localization-dependent functions of Hog1 MAPK in Cryptococcus neoformans
  16. The calcineurin pathway regulates extreme thermotolerance, cell membrane and wall integrity, antifungal resistance, and virulence in Candida auris
  17. Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans
  18. Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans
  19. Signaling pathways governing the pathobiological features and antifungal drug resistance of Candida auris
  20. Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans
  21. The calcineurin pathway regulates extreme thermotolerance, cell membrane and wall integrity, antifungal resistance, and virulence in Candida auris
  22. Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans
  23. Evolutionary unique N-glycan-dependent protein quality control system plays pivotal roles in cellular fitness and extracellular vesicle transport in Cryptococcus neoformans
  24. Sensing and responding to host-derived stress signals: lessons from fungal meningitis pathogen
  25. Unraveling the cryptic functions of mitogen-activated protein kinases Cpk2 and Mpk2 in Cryptococcus neoformans
  26. Casein kinase 2 complex: a central regulator of multiple pathobiological signaling pathways in Cryptococcus neoformans
  27. Sua5 catalyzing universal t 6 A tRNA modification is responsible for multifaceted functions of the KEOPS complex in Cryptococcus neoformans
  28. Deciphering the regulatory mechanisms of the cAMP/protein kinase A pathway and their roles in the pathogenicity of Candida auris
  29. The hybrid RAVE complex plays V-ATPase-dependent and -independent pathobiological roles in Cryptococcus neoformans
  30. Protein Kinase A Controls the Melanization of Candida auris through the Alteration of Cell Wall Components
  31. Adenylyl-Sulfate Kinase (Met14)-Dependent Cysteine and Methionine Biosynthesis Pathways Contribute Distinctively to Pathobiological Processes in Cryptococcus neoformans
  32. Dysregulating PHO Signaling via the CDK Machinery Differentially Impacts Energy Metabolism, Calcineurin Signaling, and Virulence in Cryptococcus neoformans
  33. Evaluation and Monitoring of the Natural Toxin Ptaquiloside in Bracken Fern, Meat, and Dairy Products
  34. Unraveling Capsule Biosynthesis and Signaling Networks in Cryptococcus neoformans
  35. Extension of O -Linked Mannosylation in the Golgi Apparatus Is Critical for Cell Wall Integrity Signaling and Interaction with Host Cells in Cryptococcus neoformans Pathogenesis
  36. Essential Roles of Ribonucleotide Reductases under DNA Damage and Replication Stresses in Cryptococcus neoformans
  37. Role of the Heme Activator Protein Complex in the Sexual Development of Cryptococcus neoformans
  38. Rare β-Resorcylic Acid Derivatives from a Halophyte-Associated Fungus Colletotrichum gloeosporioides JS0419 and Their Antifungal Activities
  39. Pathogens infecting the central nervous system
  40. Atypical Bacilliredoxin AbxC Plays a Role in Responding to Oxidative Stress in Radiation-Resistant Bacterium Deinococcus radiodurans
  41. Zinc-binding domain mediates pleiotropic functions of Yvh1 in Cryptococcus neoformans
  42. Fungal brain infection modelled in a human-neurovascular-unit-on-a-chip with a functional blood–brain barrier
  43. Transcriptomic and Metabolomic Analysis Revealed Roles of Yck2 in Carbon Metabolism and Morphogenesis of Candida albicans
  44. Erratum: Microbe Profile: Cryptococcus neoformans species complex
  45. A Signature-Tagged Mutagenesis (STM)-based murine-infectivity assay for Cryptococcus neoformans
  46. Corrigendum: Sho1 and Msb2 Play Complementary but Distinct Roles in Stress Responses, Sexual Differentiation, and Pathogenicity of Cryptococcus neoformans
  47. Microbe Profile: Cryptococcus neoformans species complex
  48. Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans
  49. Core N-Glycan Structures Are Critical for the Pathogenicity of Cryptococcus neoformans by Modulating Host Cell Death
  50. Fungal kinases and transcription factors regulating brain infection in Cryptococcus neoformans
  51. Antioxidant Activities of an Exopolysaccharide (DeinoPol) Produced by the Extreme Radiation-Resistant Bacterium Deinococcus radiodurans
  52. Corrigendum to: Molecular Characterization of Adenylyl Cyclase Complex Proteins Using Versatile Protein-Tagging Plasmid Systems in Cryptococcus neoformans
  53. Regulatory Mechanism of the Atypical AP-1-Like Transcription Factor Yap1 in Cryptococcus neoformans
  54. Structural analysis of fungal pathogenicity-related casein kinase α subunit, Cka1, in the human fungal pathogen Cryptococcus neoformans
  55. Unraveling Melanin Biosynthesis and Signaling Networks in Cryptococcus neoformans
  56. Biosynthesis of Nonimmunosuppressive FK506 Analogues with Antifungal Activity
  57. The TOR Pathway Plays Pleiotropic Roles in Growth and Stress Responses of the Fungal Pathogen Cryptococcus neoformans
  58. Antioxidant, Anti-inflammatory, and Neuroprotective Effects of Novel Vinyl Sulfonate Compounds as Nrf2 Activator
  59. Nutrient and Stress Sensing in Pathogenic Yeasts
  60. Rad53- and Chk1-Dependent DNA Damage Response Pathways Cooperatively Promote Fungal Pathogenesis and Modulate Antifungal Drug Susceptibility
  61. Sho1 and Msb2 Play Complementary but Distinct Roles in Stress Responses, Sexual Differentiation, and Pathogenicity of Cryptococcus neoformans
  62. In Vitro and In Vivo Assessment of FK506 Analogs as Novel Antifungal Drug Candidates
  63. Genetic Manipulation ofCryptococcus neoformans
  64. Evolutionarily Conserved and Divergent Roles of Unfolded Protein Response (UPR) in the Pathogenic Cryptococcus Species Complex
  65. Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson’s disease therapy
  66. The novel microtubule-associated CAP-glycine protein Cgp1 governs growth, differentiation, and virulence of Cryptococcus neoformans
  67. Crystal structure of inositol 1,3,4,5,6-pentakisphosphate 2-kinase from Cryptococcus neoformans
  68. Glucosamine stimulates pheromone-independent dimorphic transition in Cryptococcus neoformans by promoting Crz1 nuclear translocation
  69. Microbial radiation-resistance mechanisms
  70. A novel bZIP protein, Gsb1, is required for oxidative stress response, mating, and virulence in the human pathogen Cryptococcus neoformans
  71. The water channel protein aquaporin 1 regulates cellular metabolism and competitive fitness in a global fungal pathogen C ryptococcus neoformans
  72. Molecular Characterization of Adenylyl Cyclase Complex Proteins Using Versatile Protein-Tagging Plasmid Systems in Cryptococcus neoformans
  73. Pho4 Is Essential for Dissemination of Cryptococcus neoformans to the Host Brain by Promoting Phosphate Uptake and Growth at Alkaline pH
  74. Unraveling Fungal Radiation Resistance Regulatory Networks through the Genome-Wide Transcriptome and Genetic Analyses ofCryptococcus neoformans
  75. Rewiring of Signaling Networks Modulating Thermotolerance in the Human Pathogen Cryptococcus neoformans
  76. Systemic Approach to Virulence Gene Network Analysis for Gaining New Insight into Cryptococcal Virulence
  77. Metal Chelation as a Powerful Strategy to Probe Cellular Circuitry Governing Fungal Drug Resistance and Morphogenesis
  78. Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans
  79. Unique roles of the unfolded protein response pathway in fungal development and differentiation
  80. Intron retention-dependent gene regulation in Cryptococcus neoformans
  81. Dual action antifungal small molecule modulates multidrug efflux and TOR signaling
  82. Major Sensing Proteins in Pathogenic Fungi: The Hybrid Histidine Kinase Family
  83. Fungal physiology: Red light plugs into MAPK pathway
  84. Relative Contributions of Prenylation and Postprenylation Processing in Cryptococcus neoformans Pathogenesis
  85. Screening, Synthesis, and In Vitro Evaluation of Vinyl Sulfones as Inhibitors of Complement-Dependent Cytotoxicity in Neuromyelitis Optica
  86. An Antifungal Combination Matrix Identifies a Rich Pool of Adjuvant Molecules that Enhance Drug Activity against Diverse Fungal Pathogens
  87. A Phenylpropanoid Glycoside as a Calcineurin Inhibitor Isolated from Magnolia obovata Thunb.
  88. Exploiting Fungal Virulence-Regulating Transcription Factors As Novel Antifungal Drug Targets
  89. Systematic functional profiling of transcription factor networks in Cryptococcus neoformans
  90. Network-assisted genetic dissection of pathogenicity and drug resistance in the opportunistic human pathogenic fungus Cryptococcus neoformans
  91. Unraveling the Novel Structure and Biosynthetic Pathway ofO-Linked Glycans in the Golgi Apparatus of the Human Pathogenic YeastCryptococcus neoformans
  92. Inhibition of the Calcineurin Pathway by Two Tannins, Chebulagic Acid and Chebulanin, Isolated from Harrisonia abyssinica Oliv.
  93. 9-O-butyl-13-(4-isopropylbenzyl)berberine, KR-72, Is a Potent Antifungal Agent That Inhibits the Growth of Cryptococcus neoformans by Regulating Gene Expression
  94. Cryptococcus neoformans and Cryptococcus gattii, the Etiologic Agents of Cryptococcosis
  95. A Ferroxidase, Cfo1, Regulates Diverse Environmental Stress Responses of Cryptococcus neoformans through the HOG Pathway
  96. Analysis of the Genome and Transcriptome of Cryptococcus neoformans var. grubii Reveals Complex RNA Expression and Microevolution Leading to Virulence Attenuation
  97. Distinct and Redundant Roles of Protein Tyrosine Phosphatases Ptp1 and Ptp2 in Governing the Differentiation and Pathogenicity of Cryptococcus neoformans
  98. A Nudix Hydrolase Protein, Ysa1, Regulates Oxidative Stress Response and Antifungal Drug Susceptibility in Cryptococcus neoformans
  99. A Novel Radiation-Resistant Strain of Filobasidium sp. Isolated from the West Sea of Korea
  100. The unfolded protein response (UPR) pathway inCryptococcus
  101. Unraveling unique structure and biosynthesis pathway ofN-linked glycans in human fungal pathogenCryptococcus neoformansby glycomics analysis.
  102. Sulphiredoxin plays peroxiredoxin-dependent and -independent roles via the HOG signalling pathway inCryptococcus neoformansand contributes to fungal virulence
  103. Stress Signaling Pathways for the Pathogenicity of Cryptococcus
  104. Global transcriptome analysis of eukaryotic genes affected by gromwell extract
  105. Essential Roles of the Kar2/BiP Molecular Chaperone Downstream of the UPR Pathway in Cryptococcus neoformans
  106. Msi1-Like (MSIL) Proteins in Fungi
  107. Pleiotropic Roles of the Msi1-Like Protein Msl1 in Cryptococcus neoformans
  108. Unraveling Unique Structure and Biosynthesis Pathway ofN-Linked Glycans in Human Fungal PathogenCryptococcus neoformansby Glycomics Analysis
  109. Two cation transporters Ena1 and Nha1 cooperatively modulate ion homeostasis, antifungal drug resistance, and virulence of Cryptococcus neoformans via the HOG pathway
  110. Targeted Gene Disruption in Cryptococcus neoformans Using Double-Joint PCR with Split Dominant Selectable Markers
  111. A Flucytosine-Responsive Mbp1/Swi4-Like Protein, Mbs1, Plays Pleiotropic Roles in Antifungal Drug Resistance, Stress Response, and Virulence of Cryptococcus neoformans
  112. Unique Evolution of the UPR Pathway with a Novel bZIP Transcription Factor, Hxl1, for Controlling Pathogenicity of Cryptococcus neoformans
  113. Cryptococcal Titan Cell Formation Is Regulated by G-Protein Signaling in Response to Multiple Stimuli
  114. Multiple Roles of Ypd1 Phosphotransfer Protein in Viability, Stress Response, and Virulence Factor Regulation in Cryptococcus neoformans
  115. Hrk1 Plays Both Hog1-Dependent and -Independent Roles in Controlling Stress Response and Antifungal Drug Resistance in Cryptococcus neoformans
  116. Ste50 adaptor protein governs sexual differentiation of Cryptococcus neoformans via the pheromone-response MAPK signaling pathway
  117. Characterizing the role of RNA silencing components in Cryptococcus neoformans
  118. Comparative Transcriptome Analysis of the CO2 Sensing Pathway Via Differential Expression of Carbonic Anhydrase in Cryptococcus neoformans
  119. Corrigendum to “An efficient gene-disruption method in Cryptococcus neoformans by double-joint PCR with NAT-split markers” [Biochem. Biophys. Res. Commun. 390 (2009) 983–988]
  120. The conserved and divergent roles of carbonic anhydrases in the filamentous fungiAspergillus fumigatusandAspergillus nidulans
  121. Comparative Transcriptome Analysis Reveals Novel Roles of the Ras and Cyclic AMP Signaling Pathways in Environmental Stress Response and Antifungal Drug Sensitivity in Cryptococcus neoformans
  122. Functional Characterization of cAMP-Regulated Gene,CAR1, inCryptococcus neoformans
  123. An efficient gene-disruption method in Cryptococcus neoformans by double-joint PCR with NAT-split markers
  124. The conserved and divergent roles of carbonic anhydrases in the filamentous fungi Aspergillus fumigatus and Aspergillus nidulans
  125. Remodeling of Global Transcription Patterns of Cryptococcus neoformans Genes Mediated by the Stress-Activated HOG Signaling Pathways
  126. The Stress-Activated Signaling (SAS) Pathways of a Human Fungal Pathogen,Cryptococcus neoformans
  127. Master and Commander in Fungal Pathogens: the Two-Component System and the HOG Signaling Pathway
  128. Genome-Wide Transcriptional Profiling of the Cyclic AMP-Dependent Signaling Pathway during Morphogenic Transitions of Candida albicans
  129. Ssk2 Mitogen-Activated Protein Kinase Kinase Kinase Governs Divergent Patterns of the Stress-Activated Hog1 Signaling Pathway in Cryptococcus neoformans
  130. State of differentiation defines buccal epithelial cell affinity for cross-linking to Candida albicans Hwp1
  131. Sensing the environment: lessons from fungi
  132. CO2 sensing in fungi and beyond
  133. A Unique Fungal Two-Component System Regulates Stress Responses, Drug Sensitivity, Sexual Development, and Virulence of Cryptococcus neoformans
  134. Calcineurin, Mpk1 and Hog1 MAPK pathways independently control fludioxonil antifungal sensitivity in Cryptococcus neoformans
  135. G Protein-coupled Receptor Gpr4 Senses Amino Acids and Activates the cAMP-PKA Pathway in Cryptococcus neoformans
  136. Pde1 Phosphodiesterase Modulates Cyclic AMP Levels through a Protein Kinase A-Mediated Negative Feedback Loop in Cryptococcus neoformans
  137. Carbonic Anhydrase and CO2 Sensing during Cryptococcus neoformans Growth, Differentiation, and Virulence
  138. Deciphering the Model Pathogenic Fungus Cryptococcus Neoformans
  139. Specialization of the HOG Pathway and Its Impact on Differentiation and Virulence of Cryptococcus neoformans
  140. Adenylyl Cyclase-Associated Protein Aca1 Regulates Virulence and Differentiation of Cryptococcus neoformans via the Cyclic AMP-Protein Kinase A Cascade
  141. Expression of Transglutaminase Substrate Activity onCandida albicansGerm Tubes through a Coiled, Disulfide-bonded N-terminal Domain of Hwp1 Requires C-terminal Glycosylphosphatidylinositol Modification
  142. Increased high-affinity phosphodiesterase PDE2 gene expression in germ tubes counteracts CAP1-dependent synthesis of cyclic AMP, limits hypha production and promotes virulence of Candida albicans
  143. CAP1, an Adenylate Cyclase-Associated Protein Gene, Regulates Bud-Hypha Transitions, Filamentous Growth, and Cyclic AMP Levels and Is Required for Virulence of Candida albicans