All Stories

  1. Photoinduced Boron‐Catalyzed Direct α ‐Aminoxylation of Carboxylic Acids

    Article • ChemistryEurope, October 2025, Wiley

    Dr Yohei Shimizu

  2. Silver-Catalyzed Asymmetric Aldol Reaction of Nonactivated Ketones with α-Isocyanocarboxylic Acid Derivatives Enabled by Prolinol-phosphine-sec-amine Chiral Ligand

    Article • ACS Catalysis, September 2025, American Chemical Society (ACS)

    Dr Yohei Shimizu

  3. Phosphorus catalysis enabling α-sp3-C–H amination of 2-alkylpyridines

    Article • Organic Chemistry Frontiers, January 2025, Royal Society of Chemistry

    Dr Yohei Shimizu

  4. Oxyamination of alkenes enabled by direct photoexcitation of fluorenone oxime derivatives

    Article • Chemistry Letters, November 2024, Oxford University Press (OUP)

    Dr Yohei Shimizu

  5. Copper(I)-Catalyzed Asymmetric Nucleophilic Addition to Aldehydes with Skipped Enynes

    Article • Organic Letters, November 2024, American Chemical Society (ACS)

    Dr Yohei Shimizu

  6. Photoinduced Boron-Catalyzed β-Allylation of Carboxylic Acids Enabled by a Mixed Two-Ligand System

    Article • September 2024, American Chemical Society (ACS)

    Dr Yohei Shimizu

  7. Boron-Catalyzed Michael Reaction of Donor–Acceptor Carboxylic Acid Pairs Enabling Direct Synthesis of 1,5-Dicarboxylic Acids

    Article • Organic Letters, June 2024, American Chemical Society (ACS)

    Dr Yohei Shimizu

  8. 20.2.1.8.15 Synthesis of Carboxylic Acids with Retention of the Functional Group (Update 2024)

    Article • January 2024, Thieme Publishing Group

    Dr Yohei Shimizu

  9. Visible-Light-Induced Aminochlorination of Alkenes

    Article • Organic Letters, June 2023, American Chemical Society (ACS)

    Dr Yohei Shimizu

  10. Direct α-Trifluoromethylthiolation of Carboxylic Acids Enabled by Boron Catalysis

    Article • Synlett, April 2023, Thieme Publishing Group

    Dr Yohei Shimizu

  11. Boron‐Catalyzed α‐Functionalizations of Carboxylic Acids

    Article • The Chemical Record, January 2023, Wiley

    Dr Yohei Shimizu

  12. Boron Catalysis in the Transformation of Carboxylic Acids and Carboxylic Acid Derivatives

    Article • European Journal of Organic Chemistry, December 2022, Wiley

    Dr Yohei Shimizu

  13. Silver‐Catalyzed Asymmetric Aldol Reaction of Isocyanoacetic Acid Derivatives Enabled by Cooperative Participation of Classical and Nonclassical Hydrogen Bonds

    Article • Advanced Synthesis & Catalysis, June 2022, Wiley

    Dr Yohei Shimizu

  14. Insights into the Mechanism of Enantioselective Copper‐Catalyzed Ring‐Opening Allylic Alkylation of Cyclopropanols

    Article • Advanced Synthesis & Catalysis, April 2022, Wiley

    Dr Yohei Shimizu

  15. Visible Light-Induced Reductive Alkynylation of Aldehydes by Umpolung Approach

    Article • Organic Letters, December 2021, American Chemical Society (ACS)

    Dr Yohei Shimizu

  16. Data-driven catalyst optimization for stereodivergent asymmetric synthesis by iridium/boron hybrid catalysis

    Article • Cell Reports Physical Science, December 2021, Elsevier

    Dr Yohei Shimizu

  17. Synthesis of C,N,N-Cyclometalated Gold(III) Complexes with Anionic Amide Ligands

    Article • Synlett, October 2021, Thieme Publishing Group

    Dr Yohei Shimizu

  18. Visible-Light-Driven α-Allylation of Carboxylic Acids

    Article • ACS Catalysis, July 2021, American Chemical Society (ACS)

    Dr Yohei Shimizu

  19. Data-driven catalyst optimization for stereodivergent asymmetric synthesis of α-allyl carboxylic acids by iridium/boron hybrid catalysis

    Article • June 2021, Springer Science + Business Media

    Dr Yohei Shimizu

  20. Data-Driven Catalyst Optimization for Stereodivergent Asymmetric Synthesis of α-Allyl Carboxylic Acids by Iridium/boron Hybrid Catalysis

    Article • May 2021, American Chemical Society (ACS)

    Dr Yohei Shimizu

  21. Iridium‐Catalyzed Enantioselective Transfer Hydrogenation of Ketones Controlled by Alcohol Hydrogen‐Bonding and sp 3 ‐C−H Noncovalent Interactions

    Article • Advanced Synthesis & Catalysis, July 2020, Wiley

    Dr Yohei Shimizu

  22. Development of Copper-Catalyzed Chemoselective Reactions

    Article • Chemical and Pharmaceutical Bulletin, May 2020, Pharmaceutical Society of Japan

    Dr Yohei Shimizu

  23. Copper-catalyzed enantioselective conjugate reduction of α,β-unsaturated esters with chiral phenol–carbene ligands

    Article • Beilstein Journal of Organic Chemistry, March 2020, Beilstein Institut

    Dr Yohei Shimizu

  24. Cupid and Psyche system for the diagnosis and treatment of advanced cancer

    Article • Proceedings of the Japan Academy Series B, December 2019, Japan Academy

    Dr Yohei Shimizu

  25. Boron-Catalyzed α-Amination of Carboxylic Acids

    Article • Organic Letters, September 2019, American Chemical Society (ACS)

    Dr Yohei Shimizu

  26. Copper(I)-Catalyzed Stereodivergent Propargylation of N-Acetyl Mannosamine for Protecting Group Minimal Synthesis of C3-Substituted Sialic Acids

    Article • The Journal of Organic Chemistry, August 2019, American Chemical Society (ACS)

    Dr Yohei Shimizu

  27. Catalytic Regio- and Enantioselective Proton Migration from Skipped Enynes to Allenes

    Article • Chem, March 2019, Elsevier

    Dr Yohei Shimizu

  28. Asymmetric Synthesis of α-Alkylidene-β-Lactams through Copper Catalysis with a Prolinol-Phosphine Chiral Ligand

    Article • Organic Letters, March 2019, American Chemical Society (ACS)

    Dr Yohei Shimizu

  29. A Stable and Cleavable O-Linked Spacer for Drug Delivery Systems

    Article • Chemical and Pharmaceutical Bulletin, January 2019, Pharmaceutical Society of Japan

    Dr Yohei Shimizu

  30. Copper(I)-Catalyzed Enantio- and Diastereodivergent Borylative Coupling of Styrenes and Imines

    Article • Angewandte Chemie, May 2018, Wiley

    Dr Yohei Shimizu

  31. Chemo- and Enantioselective Pd/B Hybrid Catalysis for the Construction of Acyclic Quaternary Carbons: Migratory Allylation of O-Allyl Esters to α-C-Allyl Carboxylic Acids

    Article • Journal of the American Chemical Society, April 2018, American Chemical Society (ACS)

    Dr Yohei Shimizu

  32. Boron-Catalyzed Carboxylic Acid-Selective Aldol Reaction with Trifluoromethyl Ketones

    Article • Chemical and Pharmaceutical Bulletin, January 2018, Pharmaceutical Society of Japan

    Dr Yohei Shimizu

  33. Copper(I)-Catalyzed Enantioselective Addition of Enynes to Ketones

    Article • Journal of the American Chemical Society, March 2017, American Chemical Society (ACS)

    Dr Yohei Shimizu

  34. ChemInform Abstract: Ligand-Enabled, Copper-Catalyzed Regio- and Stereoselective Synthesis of Trialkylsubstituted Alkenylboronates from Unactivated Internal Alkynes.

    Article • ChemInform, November 2016, Wiley

    Dr Yohei Shimizu

  35. Copper(I)-Catalyzed Dehydrative C-Glycosidation of Unprotected Pyranoses with Ketones

    Article • ACS Catalysis, October 2016, American Chemical Society (ACS)

    Dr Yohei Shimizu

  36. ChemInform Abstract: Ligand-Promoted, Boron-Mediated Chemoselective Carboxylic Acid Aldol Reaction.

    Article • ChemInform, September 2016, Wiley

    Dr Yohei Shimizu

  37. Ligand-Enabled, Copper-Catalyzed Regio- and Stereoselective Synthesis of Trialkylsubstituted Alkenylboronates from Unactivated Internal Alkynes

    Article • Journal of the American Chemical Society, June 2016, American Chemical Society (ACS)

    Dr Yohei Shimizu

  38. Ligand-Promoted, Boron-Mediated Chemoselective Carboxylic Acid Aldol Reaction

    Article • Organic Letters, May 2016, American Chemical Society (ACS)

    Dr Yohei Shimizu

  39. ChemInform Abstract: Copper-Catalyzed Oxyboration of Unactivated Alkenes.

    Article • ChemInform, March 2016, Wiley

    Dr Yohei Shimizu

  40. An Expeditious Synthesis of Sialic Acid Derivatives by Copper(I)-Catalyzed Stereodivergent Propargylation of Unprotected Aldoses

    Article • ACS Central Science, January 2016, American Chemical Society (ACS)

    Dr Yohei Shimizu

  41. ChemInform Abstract: Chemoselective Boron-Catalyzed Nucleophilic Activation of Carboxylic Acids for Mannich-Type Reactions.

    Article • ChemInform, October 2015, Wiley

    Dr Yohei Shimizu

  42. Copper-Catalyzed Oxyboration of Unactivated Alkenes

    Article • Chemistry - A European Journal, September 2015, Wiley

    Dr Yohei Shimizu

  43. SYNFORM ISSUE 2015/10

    Article • Synlett, September 2015, Thieme Publishing Group

    Dr Yohei Shimizu

  44. SYNFORM ISSUE 2015/10

    Article • Synthesis, September 2015, Thieme Publishing Group

    Dr Yohei Shimizu

  45. Chemoselective Boron-Catalyzed Nucleophilic Activation of Carboxylic Acids for Mannich-Type Reactions

    Article • Journal of the American Chemical Society, June 2015, American Chemical Society (ACS)

    Dr Yohei Shimizu

  46. Design and Synthesis of Biotin Analogues Reversibly Binding with Streptavidin

    Article • Chemistry - An Asian Journal, March 2015, Wiley

    Dr Yohei Shimizu

  47. Structure-based design of a streptavidin mutant specific for an artificial biotin analogue

    Article • The Journal of Biochemistry, February 2015, Oxford University Press (OUP)

    Dr Yohei Shimizu

  48. Structure-based design and synthesis of a bivalent iminobiotin analog showing strong affinity toward a low immunogenic streptavidin mutant

    Article • Bioscience Biotechnology and Biochemistry, January 2015, Taylor & Francis

    Dr Yohei Shimizu

  49. Catalytic Asymmetric Addition Reactions of Cu(I)-Conjugated Soft Carbon Nucleophiles

    Article • January 2015, Springer Science + Business Media

    Dr Yohei Shimizu

  50. ChemInform Abstract: Copper-Catalyzed Regio- and Stereoselective Intermolecular Three-Component Oxyarylation of Allenes.

    Article • ChemInform, October 2014, Wiley

    Dr Yohei Shimizu

  51. ChemInform Abstract: Recent Progress in Copper-Catalyzed Difunctionalization of Unactivated Carbon-Carbon Multiple Bonds

    Article • ChemInform, September 2014, Wiley

    Dr Yohei Shimizu

  52. ChemInform Abstract: Catalytic Enantioselective Synthesis of 2-(2-Hydroxyethyl)indole Scaffolds via Consecutive Intramolecular Amido-Cupration of Allenes and Asymmetric Addition of Carbonyl Compounds.

    Article • ChemInform, August 2014, Wiley

    Dr Yohei Shimizu

  53. Recent progress in copper-catalyzed difunctionalization of unactivated carboncarbon multiple bonds

    Article • Tetrahedron Letters, July 2014, Elsevier

    Dr Yohei Shimizu

  54. ChemInform Abstract: A Catalytic C-C Bond-Formation with Minimal Use of Protecting Groups: Construction of Functionalized Isotetronic Acid Derivatives.

    Article • ChemInform, May 2014, Wiley

    Dr Yohei Shimizu

  55. Copper-Catalyzed Regio- and Stereoselective Intermolecular Three-Component Oxyarylation of Allenes

    Article • Organic Letters, May 2014, American Chemical Society (ACS)

    Dr Yohei Shimizu

  56. Catalytic enantioselective synthesis of 2-(2-hydroxyethyl)indole scaffolds via consecutive intramolecular amido-cupration of allenes and asymmetric addition of carbonyl compounds

    Article • Chemical Science, January 2014, Royal Society of Chemistry

    Dr Yohei Shimizu, Motomu Kanai

  57. A Catalytic C-C Bond-Formation with Minimal Use of Protecting Groups: Construction of Functionalized Isotetronic Acid Derivatives

    Article • Heterocycles, January 2014, Japan Institute of Heterocyclic Chemistry

    Dr Yohei Shimizu

  58. ChemInform Abstract: Catalytic Anomeric Aminoalkynylation of Unprotected Aldoses.

    Article • ChemInform, December 2013, Wiley

    Dr Yohei Shimizu

  59. ChemInform Abstract: In situ Catalytic Generation of Allylcopper Species for Asymmetric Allylation: Toward 1H-Isochromene Skeletons.

    Article • ChemInform, November 2013, Wiley

    Dr Yohei Shimizu

  60. Catalytic Anomeric Aminoalkynylation of Unprotected Aldoses

    Article • Organic Letters, August 2013, American Chemical Society (ACS)

    Dr Yohei Shimizu

  61. In situ Catalytic Generation of Allylcopper Species for Asymmetric Allylation: Toward 1H-Isochromene Skeletons

    Article • Angewandte Chemie, June 2013, Wiley

    Dr Yohei Shimizu

  62. In situ Catalytic Generation of Allylcopper Species for Asymmetric Allylation: Toward 1H-Isochromene Skeletons

    Article • Angewandte Chemie, June 2013, Wiley

    Dr Yohei Shimizu

  63. ChemInform Abstract: Copper(I)-Catalyzed Enantioselective Incorporation of Ketones to Cyclic Hemiaminals for the Synthesis of Versatile Alkaloid Precursors.

    Article • ChemInform, March 2013, Wiley

    Dr Yohei Shimizu

  64. From Chiral Base Catalysts to Redox-Active Catalysts: Chasing the Identity of Metal Catalysts in Carbon-Carbon Bond-Forming Reactions

    Article • Journal of Synthetic Organic Chemistry Japan, January 2013, The Society of Synthetic Organic Chemistry, Japan

    Dr Yohei Shimizu

  65. ChemInform Abstract: Cu(I)-Catalyzed α-Alkylation of Ketones with Styrene Derivatives.

    Article • ChemInform, November 2012, Wiley

    Dr Yohei Shimizu

  66. Copper(I)-Catalyzed Enantioselective Incorporation of Ketones to Cyclic Hemiaminals for the Synthesis of Versatile Alkaloid Precursors

    Article • Journal of the American Chemical Society, October 2012, American Chemical Society (ACS)

    Dr Yohei Shimizu

  67. Cu(I)-catalyzed α-alkylation of ketones with styrene derivatives

    Article • Tetrahedron Letters, August 2012, Elsevier

    Dr Yohei Shimizu

  68. ChemInform Abstract: Catalytic Asymmetric Synthesis of R207910.

    Article • ChemInform, September 2010, Wiley

    Dr Yohei Shimizu

  69. The first catalytic asymmetric total synthesis of ent-hyperforin

    Article • Tetrahedron, August 2010, Elsevier

    Dr Yohei Shimizu

  70. Catalytic Asymmetric Synthesis of R207910

    Article • Journal of the American Chemical Society, June 2010, American Chemical Society (ACS)

    Dr Yohei Shimizu

  71. Catalytic Asymmetric Total Synthesis ofent-Hyperforin

    Article • Angewandte Chemie, February 2010, Wiley

    Dr Yohei Shimizu

  72. ChemInform Abstract: Asymmetric Reductive Mannich Reaction to Ketimines Catalyzed by a Cu(I) Complex.

    Article • ChemInform, May 2009, Wiley

    Dr Yohei Shimizu

  73. Asymmetric Reductive Mannich Reaction to Ketimines Catalyzed by a Cu(I) Complex

    Article • Journal of the American Chemical Society, December 2008, American Chemical Society (ACS)

    Dr Yohei Shimizu

  74. A new approach for the construction of a highly congested bicyclic system in polycyclic polyprenylated acylphloroglucinols (PPAPs)

    Article • Tetrahedron Letters, June 2007, Elsevier

    Dr Yohei Shimizu