All Stories

  1. Genome wide-scale CRISPR-Cas9 knockout screens identify a fitness score for optimized risk stratification in colorectal cancer

    Article • Journal of Translational Medicine, June 2024, Springer Science + Business Media

    Yang Yang Zhou

  2. Targeting cellular senescence as a therapeutic vulnerability in gastric cancer

    Article • Life Sciences, June 2024, Elsevier

    Yang Yang Zhou

  3. Loss of hepatic FTCD promotes lipid accumulation and hepatocarcinogenesis by upregulating PPARγ and SREBP2

    Article • JHEP Reports, October 2023, Elsevier

    Yang Yang Zhou

  4. Sustained activation of EGFR-ERK1/2 signaling limits the response to tigecycline-induced mitochondrial respiratory deficiency in liver cancer

    Article • EBioMedicine, January 2023, Elsevier

    Yang Yang Zhou

  5. cFLIP suppression and DR5 activation sensitize senescent cancer cells to senolysis

    Article • Nature Cancer, November 2022, Springer Science + Business Media

    Yang Yang Zhou

  6. Sustained activation of EGFR-ERK1/2 signaling limits the therapeutic response to tigecycline-induced inhibition of mitochondrial translation in liver cancer

    Article • March 2022, Springer Science + Business Media

    Yang Yang Zhou

  7. Fibroblast Common Serum Response Signature‐Related Classification Affects the Tumour Microenvironment and Predicts Prognosis in Bladder Cancer

    Article • Oxidative Medicine and Cellular Longevity, January 2022, Wiley

    Yang Yang Zhou

  8. A CRISPR-Cas9 screen shows the combination efficacy of lenvatinib plus epidermal growth factor receptor inhibitors for treatment of liver cancer

    Article • Cancer Biology and Medicine, October 2021, Tsinghua University Press

    Yang Yang Zhou

  9. EGFR activation limits the response of liver cancer to lenvatinib

    Article • Nature, July 2021, Springer Science + Business Media

    Yang Yang Zhou

  10. circNDUFB2 inhibits non-small cell lung cancer progression via destabilizing IGF2BPs and activating anti-tumor immunity

    Article • Nature Communications, January 2021, Springer Science + Business Media

    Yang Yang Zhou

  11. Acidic extracellular pH induces autophagy to promote anoikis resistance of hepatocellular carcinoma cells via downregulation of miR-3663-3p

    Article • Journal of Cancer, January 2021, Ivyspring International Publisher

    Yang Yang Zhou

  12. Personalized four-category staging for predicting prognosis in patients with small bowel Adenocarcinoma: an international development and validation study

    Article • EBioMedicine, October 2020, Elsevier

    Yang Yang Zhou

  13. Inverse Association of Age with Risk of Lymph Node Metastasis in Superficial Colorectal Cancer: A Large Population-Based Study

    Article • The Oncologist, January 2020, Oxford University Press (OUP)

    Yang Yang Zhou

  14. FGF/FGFR signaling pathway involved resistance in various cancer types

    Article • Journal of Cancer, January 2020, Ivyspring International Publisher

    Yang Yang Zhou

  15. Personalized Four-Category Staging for Predicting Prognosis in Patients with Small Bowel Adenocarcinoma: An International Development and Validation Study

    Article • SSRN Electronic Journal, January 2020, Elsevier

    Yang Yang Zhou

  16. Integrated transcriptomic analysis reveals hub genes involved in diagnosis and prognosis of pancreatic cancer

    Article • Extremophiles, November 2019, Springer Science + Business Media

    Yang Yang Zhou

  17. Comparison of three lymph node staging schemes for predicting the outcome in patients with small bowel adenocarcinoma: A population-based cohort and international multicentre cohort study

    Article • EBioMedicine, March 2019, Elsevier

    Yang Yang Zhou

  18. Robust analysis of novel mRNA–lncRNA cross talk based on ceRNA hypothesis uncovers carcinogenic mechanism and promotes diagnostic accuracy in esophageal cancer

    Article • Cancer Management and Research, December 2018, Dove Medical Press

    Yang Yang Zhou

  19. Role of differentially expressed genes and long non-coding RNAs in papillary thyroid carcinoma diagnosis, progression, and prognosis

    Article • Journal of Cellular Biochemistry, July 2018, Wiley

    Yang Yang Zhou

  20. Design, synthesis, anti-lung cancer activity, and chemosensitization of tumor-selective MCACs based on ROS-mediated JNK pathway activation and NF-κB pathway inhibition

    Article • European Journal of Medicinal Chemistry, May 2018, Elsevier

    Yang Yang Zhou

  21. Combination of TNM staging and pathway based risk score models in patients with gastric cancer

    Article • Journal of Cellular Biochemistry, January 2018, Wiley

    Yang Yang Zhou

  22. Additional lymphadenectomy might not improve survival of patients with resectable metastatic colorectal adenocarcinoma of T4 stage, proximal location, poor/undifferentiation, or N3/N4 stages: a large population-based study.

    Article • Journal of Cancer, January 2018, Ivyspring International Publisher

    Yang Yang Zhou

  23. Synthesis and evaluation of asymmetric curcuminoid analogs as potential anticancer agents that downregulate NF-κB activation and enhance the sensitivity of gastric cancer cell lines to irinotecan chemotherapy

    Article • European Journal of Medicinal Chemistry, October 2017, Elsevier

    Yang Yang Zhou

  24. A novel non-ATP competitive FGFR1 inhibitor with therapeutic potential on gastric cancer through inhibition of cell proliferation, survival and migration

    Article • APOPTOSIS, March 2017, Springer Science + Business Media

    Yang Yang Zhou