All Stories

  1. Neonatal Kasai portoenterostomy for biliary atresia: Clinical characteristics and outcomes

    Article • Journal of Pediatric Surgery, August 2026, Elsevier

    Dr Yan Chen

  2. Peripheral blood CD177+ cells as an early diagnostic marker for biliary atresia: a prospective multicentre study in pediatric patients with cholestasis

    Article • Journal of Hepatology, August 2022, Elsevier

    Dr Yan Chen

  3. Down-regulation of STAT3 enhanced chemokine expression and neutrophil recruitment in biliary atresia

    Article • Clinical Science, April 2021, Portland Press Ltd.

    Dr Yan Chen

  4. Silver nanoparticle treatment ameliorates biliary atresia syndrome in rhesus rotavirus inoculated mice

    Article • Nanomedicine Nanotechnology Biology and Medicine, November 2016, Elsevier

    Dr Yan Chen

  5. Modulatory effects of adiponectin on the polarization of tumor-associated macrophages

    Article • International Journal of Cancer, March 2015, Wiley

    Dr Yan Chen

  6. Inhibition of TGF-β signaling in combination with TLR7 ligation re-programs a tumoricidal phenotype in tumor-associated macrophages

    Article • Cancer Letters, May 2013, Elsevier

    Dr Yan Chen

  7. Adiponectin Mediated MHC Class II Mismatched Cardiac Graft Rejection in Mice Is IL-4 Dependent

    Article • PLOS One, November 2012, PLOS

    Dr Yan Chen

  8. Effects of water uptake on melamine renal stone formation in mice

    Article • Nephrology Dialysis Transplantation, October 2011, Oxford University Press (OUP)

    Dr Yan Chen

  9. Mutations in the NRG1 gene are associated with Hirschsprung disease

    Article • Human Genetics, June 2011, Springer Science + Business Media

    Dr Yan Chen

  10. PPAR-γ signaling and IL-5 inhibition together prevent chronic rejection of MHC Class II–mismatched cardiac grafts

    Article • The Journal of Heart and Lung Transplantation, June 2011, Elsevier

    Dr Yan Chen

  11. Novel immunomodulatory effects of adiponectin on dendritic cell functions

    Article • International Immunopharmacology, May 2011, Elsevier

    Dr Yan Chen

  12. Fine Mapping of the NRG1 Hirschsprung's Disease Locus

    Article • PLOS One, January 2011, PLOS

    Dr Yan Chen, Dr Benjamin HK Yip

  13. ω-3 fatty acids suppress inflammatory cytokine production by macrophages and hepatocytes

    Article • Journal of Pediatric Surgery, December 2010, Elsevier

    Dr Yan Chen

  14. Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2

    Article • Human Molecular Genetics, May 2010, Oxford University Press (OUP)

    Dr Yan Chen

  15. Silver Nanoparticles Mediate Differential Responses in Keratinocytes and Fibroblasts during Skin Wound Healing

    Article • ChemMedChem, February 2010, Wiley

    Dr Yan Chen

  16. Senkyunolides reduce hydrogen peroxide-induced oxidative damage in human liver HepG2 cells via induction of heme oxygenase-1

    Article • Chemico-Biological Interactions, February 2010, Elsevier

    Dr Yan Chen

  17. Reduced RET expression in gut tissue of individuals carrying risk alleles of Hirschsprung's disease

    Article • Human Molecular Genetics, January 2010, Oxford University Press (OUP)

    Dr Yan Chen

  18. BODIPY-Based Fluorescent Probe for Peroxynitrite Detection and Imaging in Living Cells

    Article • Organic Letters, May 2009, American Chemical Society (ACS)

    Dr Yan Chen

  19. Genome-wide association study identifies NRG1 as a susceptibility locus for Hirschsprung's disease

    Article • Proceedings of the National Academy of Sciences, February 2009, Proceedings of the National Academy of Sciences

    Dr Yan Chen

  20. A Highly Specific BODIPY-Based Fluorescent Probe for the Detection of Hypochlorous Acid

    Article • Organic Letters, June 2008, American Chemical Society (ACS)

    Dr Yan Chen

  21. Combined treatment with triptolide and rapamycin prolongs graft survival in a mouse model of cardiac transplantation

    Article • Transplant International, May 2008, Wiley

    Dr Yan Chen

  22. Perturbation of Hoxb5 Signaling in Vagal Neural Crests Down-Regulates Ret Leading to Intestinal Hypoganglionosis in Mice

    Article • Gastroenterology, April 2008, Elsevier

    Dr Yan Chen

  23. LPS-induced up-regulation of TGF-  receptor 1 is associated with TNF-  expression in human monocyte-derived macrophages

    Article • Journal of Leukocyte Biology, January 2008, Society for Leukocyte Biology

    Dr Yan Chen

  24. Triptolide, a Component of Chinese Herbal Medicine, Modulates the Functional Phenotype of Dendritic Cells

    Article • Transplantation, December 2007, Wolters Kluwer Health

    Dr Yan Chen

  25. Increased iNOS-expressing macrophage in long-term surviving rat small-bowel grafts

    Article • The American Journal of Surgery, August 2007, Elsevier

    Dr Yan Chen

  26. Inhibition of Sonic Hedgehog Signaling Reduces Chronic Rejection and Prolongs Allograft Survival in a Rat Orthotopic Small Bowel Transplantation Model

    Article • Transplantation, May 2007, Wolters Kluwer Health

    Dr Yan Chen

  27. Rosiglitazone Suppresses Cyclosporin-Induced Chronic Transplant Dysfunction and Prolongs Survival of Rat Cardiac Allografts

    Article • Transplantation, January 2007, Wolters Kluwer Health

    Dr Yan Chen

  28. Sonic hedgehog promotes CD4+ T lymphocyte proliferation and modulates the expression of a subset of CD28-targeted genes

    Article • International Immunology, September 2006, Oxford University Press (OUP)

    Dr Yan Chen

  29. Depletion of intestinal resident macrophages prevents ischaemia reperfusion injury in gut

    Article • Gut, December 2004, BMJ

    Dr Yan Chen

  30. Distribution of carbon monoxide–producing neurons in human colon and in Hirschsprung's disease patients

    Article • Human Pathology, October 2002, Elsevier

    Dr Yan Chen