All Stories

  1. Pyruvate Kinase M1/2 Proteoformics for Accurate Insights into Energy Metabolism Abnormity to Promote the Overall Management of Ovarian Cancer Towards Predictive, Preventive, and Personalized Medicine Approaches

    Article • Metabolites, March 2025, MDPI AG

    Professor Xianquan Zhan

  2. Personalized Drug Therapy: Innovative Concept Guided With Proteoformics

    Article • Molecular & Cellular Proteomics, March 2024, Elsevier

    Professor Xianquan Zhan

  3. Nitroproteomics is instrumental for stratification and targeted treatments of astrocytoma patients: expert recommendations for advanced 3PM approach with improved individual outcomes

    Article • The EPMA Journal, December 2023, Springer Science + Business Media

    Professor Xianquan Zhan

  4. Quantitative phosphoproteomics reveals molecular pathway network alterations in human early-stage primary hepatic carcinomas: potential for 3P medical approach

    Article • The EPMA Journal, August 2023, Springer Science + Business Media

    Professor Xianquan Zhan

  5. Growth hormone proteoformics atlas created to promote predictive, preventive, and personalized approach in overall management of pituitary neuroendocrine tumors

    Article • The EPMA Journal, June 2023, Springer Science + Business Media

    Professor Xianquan Zhan

  6. Editorial: New molecular targets involved in lung adenocarcinoma

    Article • Frontiers in Endocrinology, January 2023, Frontiers

    Professor Xianquan Zhan

  7. DNA and histone modifications as potent diagnostic and therapeutic targets to advance non-small cell lung cancer management from the perspective of 3P medicine

    Article • The EPMA Journal, November 2022, Springer Science + Business Media

    Professor Xianquan Zhan

  8. Tangled quest of post-COVID-19 infection-caused neuropathology and what 3P nano-bio-medicine can solve?

    Article • The EPMA Journal, June 2022, Springer Science + Business Media

    Professor Xianquan Zhan

  9. Comprehensive analysis of spliceosome genes and their mutants across 27 cancer types in 9070 patients: clinically relevant outcomes in the context of 3P medicine

    Article • The EPMA Journal, May 2022, Springer Science + Business Media

    Professor Xianquan Zhan

  10. The comparison between 2DE‐MS and bottom‐up LC‐MS demands high‐end techniques for both technologies

    Article • Electrophoresis, April 2022, Wiley

    Professor Xianquan Zhan

  11. Muti-omics integration analysis revealed molecular network alterations in human nonfunctional pituitary neuroendocrine tumors in the framework of 3P medicine

    Article • The EPMA Journal, February 2022, Springer Science + Business Media

    Professor Xianquan Zhan

  12. Machine Learning Identifies Pan‐Cancer Landscape of Nrf2 Oxidative Stress Response Pathway‐Related Genes

    Article • Oxidative Medicine and Cellular Longevity, January 2022, Wiley

    Professor Xianquan Zhan

  13. Mitochondrial Dysfunction Pathway Alterations Offer Potential Biomarkers and Therapeutic Targets for Ovarian Cancer

    Article • Oxidative Medicine and Cellular Longevity, January 2022, Wiley

    Professor Xianquan Zhan

  14. Integrated genomic analysis of proteasome alterations across 11,057 patients with 33 cancer types: clinically relevant outcomes in framework of 3P medicine

    Article • The EPMA Journal, September 2021, Springer Science + Business Media

    Professor Xianquan Zhan

  15. Introductory Chapter: Metabolomics

    Article • September 2021, IntechOpen

    Professor Xianquan Zhan

  16. Comprehensive Analysis of Alteration Landscape and Its Clinical Significance of Mitochondrial Energy Metabolism Pathway‐Related Genes in Lung Cancers

    Article • Oxidative Medicine and Cellular Longevity, January 2021, Wiley

    Professor Xianquan Zhan

  17. Ubiquitin - Proteasome Pathway

    Article • December 2020, IntechOpen

    Professor Xianquan Zhan

  18. SILAC quantitative proteomics analysis of ivermectin‐related proteomic profiling and molecular network alterations in human ovarian cancer cells

    Article • Journal of Mass Spectrometry, October 2020, Wiley

    Professor Xianquan Zhan

  19. Quantitative proteomics revealed energy metabolism pathway alterations in human epithelial ovarian carcinoma and their regulation by the antiparasite drug ivermectin: data interpretation in the context of 3P medicine

    Article • The EPMA Journal, October 2020, Springer Science + Business Media

    Professor Xianquan Zhan

  20. Quantitative proteomics reveals a broad‐spectrum antiviral property of ivermectin, benefiting for COVID‐19 treatment

    Article • Journal of Cellular Physiology, September 2020, Wiley

    Professor Xianquan Zhan

  21. Integration of quantitative phosphoproteomics and transcriptomics revealed phosphorylation-mediated molecular events as useful tools for a potential patient stratification and personalized treatment of human nonfunctional pituitary adenomas

    Article • The EPMA Journal, August 2020, Springer Science + Business Media

    Professor Xianquan Zhan

  22. Identification of pathology-specific regulators of m6A RNA modification to optimize lung cancer management in the context of predictive, preventive, and personalized medicine

    Article • The EPMA Journal, July 2020, Springer Science + Business Media

    Professor Xianquan Zhan

  23. Proteoforms - Concept and Applications in Medical Sciences

    Article • July 2020, IntechOpen

    Professor Xianquan Zhan

  24. Anti-parasite drug ivermectin can suppress ovarian cancer by regulating lncRNA-EIF4A3-mRNA axes

    Article • The EPMA Journal, May 2020, Springer Science + Business Media

    Professor Xianquan Zhan

  25. Label-free quantitative identification of abnormally ubiquitinated proteins as useful biomarkers for human lung squamous cell carcinomas

    Article • The EPMA Journal, January 2020, Springer Science + Business Media

    Professor Xianquan Zhan

  26. Multiomics-Based Signaling Pathway Network Alterations in Human Non-functional Pituitary Adenomas

    Article • Frontiers in Endocrinology, December 2019, Frontiers

    Professor Xianquan Zhan

  27. Chronic inflammation: key player and biomarker-set to predict and prevent cancer development and progression based on individualized patient profiles

    Article • The EPMA Journal, November 2019, Springer Science + Business Media

    Professor Xianquan Zhan

  28. Preparation of Mitochondria from Ovarian Cancer Tissues and Control Ovarian Tissues for Quantitative Proteomics Analysis

    Article • Journal of Visualized Experiments, November 2019, MyJove Corporation

    Professor Xianquan Zhan

  29. Preparation of Mitochondria from Ovarian Cancer Tissues and Control Ovarian Tissues for Quantitative Proteomics Analysis

    Article • Journal of Visualized Experiments, November 2019, MyJove Corporation

    Professor Xianquan Zhan

  30. Energy Metabolism Heterogeneity-Based Molecular Biomarkers for Ovarian Cancer

    Article • November 2019, IntechOpen

    Professor Xianquan Zhan

  31. Innovating the Concept and Practice of Two-Dimensional Gel Electrophoresis in the Analysis of Proteomes at the Proteoform Level

    Article • Proteomes, October 2019, MDPI AG

    Professor Xianquan Zhan

  32. TMT-based quantitative proteomics revealed follicle-stimulating hormone (FSH)-related molecular characterizations for potentially prognostic assessment and personalized treatment of FSH-positive non-functional pituitary adenomas

    Article • The EPMA Journal, August 2019, Springer Science + Business Media

    Professor Xianquan Zhan

  33. Identification of clinical trait–related lncRNA and mRNA biomarkers with weighted gene co-expression network analysis as useful tool for personalized medicine in ovarian cancer

    Article • The EPMA Journal, July 2019, Springer Science + Business Media

    Professor Xianquan Zhan

  34. Signaling pathway network alterations in human ovarian cancers identified with quantitative mitochondrial proteomics

    Article • The EPMA Journal, June 2019, Springer Science + Business Media

    Professor Xianquan Zhan

  35. Quantitative analysis of the mitochondrial proteome in human ovarian carcinomas

    Article • Endocrine Related Cancer, October 2018, Bioscientifica

    Professor Xianquan Zhan

  36. The differentially mitochondrial proteomic dataset in human ovarian cancer relative to control tissues

    Article • Data in Brief, October 2018, Elsevier

    Professor Xianquan Zhan

  37. Protein Tyrosine Nitration in Lung Cancer: Current Research Status and Future Perspectives

    Article • Current Medicinal Chemistry, September 2018, Bentham Science Publishers

    Professor Xianquan Zhan

  38. Exploration of variations in proteome and metabolome for predictive diagnostics and personalized treatment algorithms: Innovative approach and examples for potential clinical application

    Article • Journal of Proteomics, September 2018, Elsevier

    Professor Xianquan Zhan

  39. Prolactin Variants in Human Pituitaries and Pituitary Adenomas Identified With Two-Dimensional Gel Electrophoresis and Mass Spectrometry

    Article • Frontiers in Endocrinology, August 2018, Frontiers

    Professor Xianquan Zhan

  40. The lncRNA SNHG3 regulates energy metabolism of ovarian cancer by an analysis of mitochondrial proteomes

    Article • Gynecologic Oncology, August 2018, Elsevier

    Professor Xianquan Zhan

  41. Two-dimensional Gel Electrophoresis Coupled with Mass Spectrometry Methods for an Analysis of Human Pituitary Adenoma Tissue Proteome

    Article • Journal of Visualized Experiments, April 2018, MyJove Corporation

    Professor Xianquan Zhan

  42. The crucial role of multiomic approach in cancer research and clinically relevant outcomes

    Article • The EPMA Journal, February 2018, Springer Science + Business Media

    Professor Xianquan Zhan

  43. Every 2D spot contains over 50 to several hundreds of proteins - revival of 2DE-LC/MS in proteomics

    Article • Electrophoresis, February 2018, Wiley

    Professor Xianquan Zhan

  44. Revival of 2DE-LC/MS in Proteomics and Its Potential for Large-Scale Study of Human Proteoforms

    Article • Med One, January 2018, Qingres Limited

    Professor Xianquan Zhan

  45. Pattern recognition for predictive, preventive, and personalized medicine in cancer

    Article • The EPMA Journal, March 2017, Springer Science + Business Media

    Professor Xianquan Zhan

  46. Editorial: Systems Biological Aspects of Pituitary Tumors

    Article • Frontiers in Endocrinology, June 2016, Frontiers

    Professor Xianquan Zhan

  47. Human Pituitary Adenoma Proteomics: New Progresses and Perspectives

    Article • Frontiers in Endocrinology, May 2016, Frontiers

    Professor Xianquan Zhan

  48. Exploration of Molecular Network Variations in Different Subtypes of Human Non-functional Pituitary Adenomas

    Article • Frontiers in Endocrinology, February 2016, Frontiers

    Professor Xianquan Zhan

  49. Proteomic and functional profiles of a follicle-stimulating hormone positive human nonfunctional pituitary adenoma

    Article • Electrophoresis, June 2015, Wiley

    Professor Xianquan Zhan

  50. EPMA position paper in cancer: current overview and future perspectives

    Article • The EPMA Journal, April 2015, Springer Science + Business Media

    Professor Xianquan Zhan, Dr. Rostyslav V Bubnov

  51. Heterogeneity analysis of the proteomes in clinically nonfunctional pituitary adenomas

    Article • BMC Medical Genomics, December 2014, Springer Science + Business Media

    Professor Xianquan Zhan

  52. Identification of the proteomic variations of invasive relative to noninvasive nonfunctional pituitary adenomas

    Article • Electrophoresis, April 2014, Wiley

    Professor Xianquan Zhan

  53. Multi-parameter systematic strategy opinion that predicts, prevents, and personalized treats a cancer

    Article • The EPMA Journal, February 2014, Springer Science + Business Media

    Professor Xianquan Zhan

  54. Mass spectrometry analysis of nitrotyrosine‐containing proteins

    Article • Mass Spectrometry Reviews, December 2013, Wiley

    Professor Xianquan Zhan

  55. Mapping the interactome of overexpressed RAF kinase inhibitor protein in a gastric cancer cell line

    Article • BMC Cancer, November 2013, Springer Science + Business Media

    Professor Xianquan Zhan, Dr William C Cho

  56. Identification of stromal differentially expressed proteins in the colon carcinoma by quantitative proteomics

    Article • Electrophoresis, June 2013, Wiley

    Professor Xianquan Zhan

  57. Multi-parameter systematic strategies for predictive, preventive and personalised medicine in cancer

    Article • The EPMA Journal, January 2013, Springer Science + Business Media

    Professor Xianquan Zhan

  58. Pituitary Adenoma Nitroproteomics: Current Status and Perspectives

    Article • Oxidative Medicine and Cellular Longevity, January 2013, Hindawi Publishing Corporation

    Professor Xianquan Zhan

  59. Mitochondrial proteomics of nasopharyngeal carcinoma metastasis

    Article • BMC Medical Genomics, December 2012, Springer Science + Business Media

    Professor Xianquan Zhan

  60. Identification of differentially expressed proteins in the spinal cord of neuropathic pain models with PKCgamma silence by proteomic analysis

    Article • Brain Research, February 2012, Elsevier

    Professor Xianquan Zhan

  61. Proteomic and Bioinformatics Analyses of Mouse Liver Microsomes

    Article • International Journal of Proteomics, January 2012, Hindawi Publishing Corporation

    Professor Xianquan Zhan

  62. The use of variations in proteomes to predict, prevent, and personalize treatment for clinically nonfunctional pituitary adenomas

    Article • The EPMA Journal, June 2010, Springer Science + Business Media

    Professor Xianquan Zhan

  63. Signaling pathway networks mined from human pituitary adenoma proteomics data

    Article • BMC Medical Genomics, April 2010, Springer Science + Business Media

    Professor Xianquan Zhan

  64. MALDI-induced fragmentation of leucine enkephalin, nitro-Tyr-leucine enkaphalin, and d5-Phe-nitro-Tyr-leucine enkephalin

    Article • International Journal of Mass Spectrometry, October 2009, Elsevier

    Professor Xianquan Zhan

  65. Detection of Nitrotyrosine-Containing Proteins

    Article • January 2009, Springer Science + Business Media

    Professor Xianquan Zhan

  66. Mass Spectrometric Identification of In Vivo Nitrotyrosine Sites in the Human Pituitary Tumor Proteome

    Article • January 2009, Springer Science + Business Media

    Professor Xianquan Zhan

  67. Molecular pathogenesis of human prolactinomas identified by gene expression profiling, RT-qPCR, and proteomic analyses

    Article • Pituitary, January 2008, Springer Science + Business Media

    Professor Xianquan Zhan

  68. The human pituitary proteome: clinical applications

    Article • January 2008, Elsevier

    Professor Xianquan Zhan

  69. Linear ion-trap mass spectrometric characterization of human pituitary nitrotyrosine-containing proteins

    Article • International Journal of Mass Spectrometry, January 2007, Elsevier

    Professor Xianquan Zhan

  70. Nitroproteins from a human pituitary adenoma tissue discovered with a nitrotyrosine affinity column and tandem mass spectrometry

    Article • Analytical Biochemistry, July 2006, Elsevier

    Professor Xianquan Zhan

  71. Proteomics analysis of growth hormone isoforms in the human pituitary

    Article • PROTEOMICS, April 2005, Wiley

    Professor Xianquan Zhan

  72. Comparative proteomics analysis of human pituitary adenomas: Current status and future perspectives

    Article • Mass Spectrometry Reviews, January 2005, Wiley

    Professor Xianquan Zhan

  73. The human pituitary nitroproteome: detection of nitrotyrosyl-proteins with two-dimensional Western blotting, and amino acid sequence determination with mass spectrometry

    Article • Biochemical and Biophysical Research Communications, December 2004, Elsevier

    Professor Xianquan Zhan

  74. Heterogeneity Analysis of the Human Pituitary Proteome

    Article • Clinical Chemistry, October 2003, Oxford University Press (OUP)

    Professor Xianquan Zhan

  75. Comparative proteomics analysis of human lung squamous carcinoma

    Article • Biochemical and Biophysical Research Communications, September 2003, Elsevier

    Professor Xianquan Zhan

  76. Differences in the spatial and quantitative reproducibility between two second-dimensional gel electrophoresis systems

    Article • Electrophoresis, June 2003, Wiley

    Professor Xianquan Zhan

  77. Spot volume vs. amount of protein loaded onto a gel: A detailed, statistical comparison of two gel electrophoresis systems

    Article • Electrophoresis, June 2003, Wiley

    Professor Xianquan Zhan

  78. A reference map of a human pituitary adenoma proteome

    Article • PROTEOMICS, May 2003, Wiley

    Professor Xianquan Zhan

  79. Proteomics and Transcriptomics Analyses of Secretagogin Down-Regulation in Human Non-Functional Pituitary Adenomas

    Article • Pituitary, January 2003, Springer Science + Business Media

    Professor Xianquan Zhan