All Stories

  1. Anti-neuraminidase and anti-hemagglutinin immune serum can confer inter-lineage cross protection against recent influenza B

    Article • PLoS ONE, January 2023, PLOS

    Xavier Saelens

  2. Antibodies directed towards neuraminidase restrict influenza virus replication in primary human bronchial epithelial cells

    Article • PLoS ONE, January 2022, PLOS

    Xavier Saelens

  3. Respiratory syncytial virus nonstructural proteins 1 and 2: Exceptional disrupters of innate immune responses

    Article • PLoS Pathogens, October 2019, PLOS

    Xavier Saelens

  4. Vaccines against human respiratory syncytial virus in clinical trials, where are we now?

    Article • Expert Review of Vaccines, October 2019, Taylor & Francis

    Xavier Saelens

  5. Antibodies directed towards neuraminidase N1 control disease in a mouse model of influenza

    Article • Journal of Virology, November 2017, ASM Journals

    Xavier Saelens

  6. Hierarchical and Redundant Roles of Activating FcγRs in Protection against Influenza Disease by M2e-Specific IgG1 and IgG2a Antibodies

    Article • Journal of Virology, January 2017, ASM Journals

    Dr Karim El Bakkouri, Xavier Saelens

  7. Crystal Structure of the Conserved Amino Terminus of the Extracellular Domain of Matrix Protein 2 of Influenza A Virus Gripped by an Antibody

    Article • Journal of Virology, October 2015, ASM Journals

    Xavier Saelens

  8. Functional Comparison of Mx1 from Two Different Mouse Species Reveals the Involvement of Loop L4 in the Antiviral Activity against Influenza A Viruses

    Article • Journal of Virology, August 2015, ASM Journals

    Xavier Saelens

  9. The C terminus of NS1 protein of influenza A/WSN/1933(H1N1) virus modulates antiviral responses in infected human macrophages and mice

    Article • Journal of General Virology, August 2015, Society for General Microbiology

    Xavier Saelens

  10. Protection against Influenza A Virus Challenge with M2e-Displaying Filamentous Escherichia coli Phages

    Article • PLoS ONE, May 2015, PLOS

    Xavier Saelens

  11. Co-immunoprecipitation of the Mouse Mx1 Protein with the Influenza A Virus Nucleoprotein

    Article • Journal of Visualized Experiments, April 2015, MyJove Corporation

    Xavier Saelens

  12. A GFP Expressing Influenza A Virus to Report In Vivo Tropism and Protection by a Matrix Protein 2 Ectodomain-Specific Monoclonal Antibody

    Article • PLoS ONE, March 2015, PLOS

    Xavier Saelens

  13. Scop3D: Three-dimensional visualization of sequence conservation

    Article • PROTEOMICS, March 2015, Wiley

    Xavier Saelens

  14. Small hydrophobic protein of respiratory syncytial virus as a novel vaccine antigen

    Article • Immunotherapy, March 2015, Future Medicine

    Xavier Saelens

  15. M2e-Based Universal Influenza A Vaccines

    Article • Vaccines, February 2015, MDPI AG

    Xavier Saelens

  16. Structure of the Extracellular Domain of Matrix Protein 2 of Influenza A Virus in Complex with a Protective Monoclonal Antibody

    Article • Journal of Virology, January 2015, ASM Journals

    Xavier Saelens, Kyung Hyun Kim

  17. Analysis of the genetic diversity of influenza A viruses using next-generation DNA sequencing

    Article • BMC Genomics, January 2015, Springer Science + Business Media

    Xavier Saelens

  18. Sequence-dependent Internalization of Aggregating Peptides

    Article • Journal of Biological Chemistry, November 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Xavier Saelens

  19. CD8+ T cell immunity against human respiratory syncytial virus

    Article • Vaccine, October 2014, Elsevier

    Xavier Saelens

  20. Influenza vaccines to control influenza-associated bacterial infection: where do we stand?

    Article • Expert Review of Vaccines, September 2014, Taylor & Francis

    Xavier Saelens

  21. Insight into Highly Conserved H1 Subtype-Specific Epitopes in Influenza Virus Hemagglutinin

    Article • PLoS ONE, February 2014, PLOS

    Xavier Saelens

  22. Presenting heterologous epitopes with hepatitis B core-based virus-like particles

    Article • January 2014, Future Medicine

    Xavier Saelens

  23. Challenges and advances towards the rational design of mRNA vaccines

    Article • Trends in Molecular Medicine, December 2013, Elsevier

    Xavier Saelens

  24. M2e-Displaying Virus-Like Particles with Associated RNA Promote T Helper 1 Type Adaptive Immunity against Influenza A

    Article • PLoS ONE, March 2013, PLOS

    Xavier Saelens

  25. Hepatitis B core–based virus–like particles to present heterologous epitopes

    Article • Expert Review of Vaccines, February 2013, Taylor & Francis

    Xavier Saelens

  26. Influenza vaccines: T-cell responses deserve more attention

    Article • Expert Review of Vaccines, August 2012, Taylor & Francis

    Professor Geert Leroux-Roels, Xavier Saelens

  27. Single Domain Camelid Antibodies that Neutralize Negative Strand Viruses

    Article • March 2012, IntechOpen

    Xavier Saelens

  28. A20 (Tnfaip3) Deficiency in Myeloid Cells Protects against Influenza A Virus Infection

    Article • PLoS Pathogens, March 2012, PLOS

    Xavier Saelens

  29. Cutting Edge Approaches Toward Novel and Cross-Protective Influenza Vaccines

    Article • January 2012, Springer Science + Business Media

    Xavier Saelens, Dr Karim El Bakkouri

  30. Nanobodies®: New ammunition to battle viruses

    Article • Antiviral Research, December 2011, Elsevier

    Xavier Saelens

  31. Assessment of the Antiviral Properties of Recombinant Porcine SP-D against Various Influenza A Viruses In Vitro

    Article • PLoS ONE, September 2011, PLOS

    Xavier Saelens

  32. A novel non-toxic combined CTA1-DD and ISCOMS adjuvant vector for effective mucosal immunization against influenza virus

    Article • Vaccine, May 2011, Elsevier

    Xavier Saelens, Dr Karim El Bakkouri

  33. Llama-Derived Single Domain Antibodies to Build Multivalent, Superpotent and Broadened Neutralizing Anti-Viral Molecules

    Article • PLoS ONE, April 2011, PLOS

    Professor Nigel James Temperton, Xavier Saelens

  34. Controlling Influenza by Cytotoxic T-Cells: Calling for Help from Destroyers

    Article • Journal of Biomedicine and Biotechnology, January 2010, Hindawi Publishing Corporation

    Xavier Saelens

  35. M2e-based universal influenza A vaccine

    Article • Vaccine, October 2009, Elsevier

    Xavier Saelens, Dr Karim El Bakkouri

  36. Universal M2 ectodomain-based influenza A vaccines: preclinical and clinical developments

    Article • Expert Review of Vaccines, April 2009, Taylor & Francis

    Xavier Saelens

  37. Universal influenza A M2e-HBc vaccine protects against disease even in the presence of pre-existing anti-HBc antibodies

    Article • Vaccine, December 2008, Elsevier

    Xavier Saelens

  38. The influenza matrix protein 2 as a vaccine target

    Article • Future Virology, March 2008, Future Medicine

    Xavier Saelens

  39. An Influenza A Vaccine Based on Tetrameric Ectodomain of Matrix Protein 2

    Article • Journal of Biological Chemistry, February 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Xavier Saelens

  40. CTA1-M2e-DD: A novel mucosal adjuvant targeted influenza vaccine

    Article • Vaccine, February 2008, Elsevier

    Xavier Saelens, Dr Karim El Bakkouri

  41. Improved design and intranasal delivery of an M2e-based human influenza A vaccine

    Article • Vaccine, November 2006, Elsevier

    Xavier Saelens

  42. The universal influenza vaccine M2e-HBc administered intranasally in combination with the adjuvant CTA1-DD provides complete protection

    Article • Vaccine, January 2006, Elsevier

    Xavier Saelens

  43. Toxic proteins released from mitochondria in cell death

    Article • Oncogene, April 2004, Nature

    Xavier Saelens

  44. Use of HDEL-tagged Trichoderma reesei mannosyl oligosaccharide 1,2-α-D -mannosidase for N -glycan engineering in Pichia pastoris

    Article • FEBS Letters, August 2001, Wiley

    Xavier Saelens

  45. Protection of mice against a lethal influenza virus challenge after immunization with yeast-derived secreted influenza virus hemagglutinin

    Article • European Journal of Biochemistry, February 1999, Wiley

    Xavier Saelens

  46. In vitro Conversion of the Carbohydrate Moiety of Fungal Glycoproteins to Mammalian-type Oligosaccharides. Evidence for N -acetylglucosaminyltransferase-I-accepting Glycans from Trichoderma reesei

    Article • European Journal of Biochemistry, November 1997, Wiley

    Xavier Saelens

  47. Protection of Mice Against a Lethal Influenza Challenge by Immunization with Yeast-Derived Recombinant Influenza Neuraminidase

    Article • European Journal of Biochemistry, July 1997, Wiley

    Xavier Saelens

  48. A Fairly Conserved Epitope on the Hemagglutinin of Influenza A (H3N2) Virus with Variable Accessibility to Neutralizing Antibody

    Article • Virology, October 1995, Elsevier

    Xavier Saelens