All Stories

  1. A Fur family protein BosR is a novel RNA-binding protein that controls rpoS RNA stability in the Lyme disease pathogen

    Article • Nucleic Acids Research, February 2024, Oxford University Press (OUP)

    X. Frank Yang

  2. BadR directly represses the expression of the glycerol utilization operon in the Lyme disease pathogen

    Article • Journal of Bacteriology, January 2024, ASM Journals

    X. Frank Yang

  3. YebC Modulates OspC and VlsE Inverse Regulation and VlsE Expression in Persistent Lyme Disease

    Article • Proceedings of IMPRS, January 2024, IUPUI University Library

    X. Frank Yang

  4. The Rrp2-RpoN-RpoS pathway plays an important role in the blood-brain barrier transmigration of the Lyme disease pathogen

    Article • Infection and Immunity, November 2023, ASM Journals

    X. Frank Yang

  5. Borrelia burgdorferic-di-AMP induces type I IFN response in macrophage through the activation of STING signaling pathway

    Article • The Journal of Immunology, May 2023, The American Association of Immunologists

    X. Frank Yang

  6. Host blood meal identity modifies vector gene expression and competency

    Article • Molecular Ecology, March 2022, Wiley

    X. Frank Yang

  7. Gene Regulation and Transcriptomics

    Article • Current Issues in Molecular Biology, January 2022, MDPI AG

    X. Frank Yang

  8. Gene Regulation and Transcriptomics

    Article • January 2021, Caister Academic Press

    X. Frank Yang

  9. Role of HK2 in the Enzootic Cycle of Borrelia burgdorferi

    Article • Frontiers in Medicine, October 2020, Frontiers

    X. Frank Yang

  10. YebC regulates variable surface antigen VlsE expression and is required for host immune evasion in Borrelia burgdorferi

    Article • PLoS Pathogens, October 2020, PLOS

    X. Frank Yang

  11. Comparative vector competence of North American Lyme disease vectors

    Article • Parasites & Vectors, January 2020, Springer Science + Business Media

    X. Frank Yang

  12. Protective Immunity and New Vaccines for Lyme Disease

    Article • Clinical Infectious Diseases, October 2019, Oxford University Press (OUP)

    X. Frank Yang

  13. Positive and Negative Regulation of Glycerol Utilization by the c-di-GMP Binding Protein PlzA in Borrelia burgdorferi

    Article • Journal of Bacteriology, September 2018, ASM Journals

    X. Frank Yang

  14. The oligopeptide ABC transporter OppA4 negatively regulates the virulence factor OspC production of the Lyme disease pathogen

    Article • Ticks and Tick-borne Diseases, July 2018, Elsevier

    X. Frank Yang

  15. The sigma factor σ54 is required for the long‐term survival of Leptospira biflexa in water

    Article • Molecular Microbiology, May 2018, Wiley

    X. Frank Yang

  16. Identification of Acetylated Proteins in Borrelia burgdorferi

    Article • October 2017, Springer Science + Business Media

    X. Frank Yang

  17. The EbpA-RpoN Regulatory Pathway of the Pathogen Leptospira interrogans Is Essential for Survival in the Environment

    Article • Applied and Environmental Microbiology, November 2016, ASM Journals

    X. Frank Yang

  18. Insight into the Dual Functions of Bacterial Enhancer-Binding Protein Rrp2 of Borrelia burgdorferi

    Article • Journal of Bacteriology, March 2016, ASM Journals

    X. Frank Yang

  19. Outer Surface Protein OspC Is an Antiphagocytic Factor That Protects Borrelia burgdorferi from Phagocytosis by Macrophages

    Article • Infection and Immunity, October 2015, ASM Journals

    X. Frank Yang, Dr C. Henrique Serezani

  20. Prioritizing drug targets in Clostridium botulinum with a computational systems biology approach

    Article • Genomics, July 2014, Elsevier

    X. Frank Yang

  21. DhhP, a Cyclic di-AMP Phosphodiesterase of Borrelia burgdorferi, Is Essential for Cell Growth and Virulence

    Article • Infection and Immunity, February 2014, ASM Journals

    X. Frank Yang

  22. Cyclic Di-GMP Receptor PlzA Controls Virulence Gene Expression through RpoS in Borrelia burgdorferi

    Article • Infection and Immunity, November 2013, ASM Journals

    X. Frank Yang

  23. Manganese and Zinc Regulate Virulence Determinants in Borrelia burgdorferi

    Article • Infection and Immunity, May 2013, ASM Journals

    X. Frank Yang

  24. Rrp2, a Prokaryotic Enhancer-Like Binding Protein, Is Essential for Viability of Borrelia burgdorferi

    Article • Journal of Bacteriology, April 2012, ASM Journals

    X. Frank Yang

  25. Role of Acetyl-Phosphate in Activation of the Rrp2-RpoN-RpoS Pathway in Borrelia burgdorferi

    Article • PLoS Pathogens, September 2010, PLOS

    X. Frank Yang

  26. Role of the Surface Lipoprotein BBA07 in the Enzootic Cycle of Borrelia burgdorferi

    Article • Infection and Immunity, April 2010, ASM Journals

    X. Frank Yang

  27. Characterization of the Highly Regulated Antigen BBA05 in the Enzootic Cycle of Borrelia burgdorferi

    Article • Infection and Immunity, October 2009, ASM Journals

    X. Frank Yang

  28. Rrp2, a σ54-Dependent Transcriptional Activator of Borrelia burgdorferi, Activates rpoS in an Enhancer-Independent Manner

    Article • Journal of Bacteriology, February 2009, ASM Journals

    X. Frank Yang

  29. Abrogation of ospAB constitutively activates the Rrp2‐RpoN‐RpoS pathway (sigmaN‐sigmaS cascade) in Borrelia burgdorferi

    Article • Molecular Microbiology, November 2008, Wiley

    X. Frank Yang

  30. Essential Role of the Response Regulator Rrp2 in the Infectious Cycle of Borrelia burgdorferi

    Article • Infection and Immunity, June 2008, ASM Journals

    X. Frank Yang

  31. Identification of Rrp2‐Controlled Mammalian Infection‐Associated Proteins in Borrelia Burgdorferi

    Article • The FASEB Journal, April 2007, Wiley

    X. Frank Yang

  32. The Lyme disease agent exploits a tick protein to infect the mammalian host

    Article • Nature, July 2005, Springer Science + Business Media

    X. Frank Yang

  33. Analysis of the ospC Regulatory Element Controlled by the RpoN-RpoS Regulatory Pathway in Borrelia burgdorferi

    Article • Journal of Bacteriology, July 2005, ASM Journals

    X. Frank Yang

  34. Essential Role for OspA/B in the Life Cycle of the Lyme Disease Spirochete

    Article • Journal of Experimental Medicine, February 2004, Rockefeller University Press

    X. Frank Yang

  35. The response regulator Rrp2 is essential for the expression of major membrane lipoproteins in Borrelia burgdorferi

    Article • Proceedings of the National Academy of Sciences, August 2003, Proceedings of the National Academy of Sciences

    X. Frank Yang