All Stories

  1. Paradoxical Embolization via Large Pulmonary Arteriovenous Malformation

    Article • American Journal of Respiratory and Critical Care Medicine, September 2019, American Thoracic Society

    William Oldham

  2. Innate T cells in the intensive care unit

    Article • Molecular Immunology, January 2019, Elsevier

    William Oldham

  3. MicroRNA Dysregulation in Pulmonary Arteries from Chronic Obstructive Pulmonary Disease. Relationships with Vascular Remodeling

    Article • American Journal of Respiratory Cell and Molecular Biology, October 2018, American Thoracic Society

    William Oldham

  4. The Long Noncoding RNA LnRPT Puts the Brakes on Pulmonary Artery Smooth Muscle Cell Proliferation

    Article • American Journal of Respiratory Cell and Molecular Biology, February 2018, American Thoracic Society

    William Oldham

  5. p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis

    Article • Cancer Research, May 2017, American Association for Cancer Research (AACR)

    Dr Mustafa Sahin, William Oldham

  6. Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension

    Article • Journal of Clinical Investigation, August 2016, American Society for Clinical Investigation

    William Oldham

  7. Unexplained exertional dyspnea caused by low ventricular filling pressures: results from clinical invasive cardiopulmonary exercise testing

    Article • Pulmonary Circulation, March 2016, University of Chicago Press

    William Oldham

  8. Elevated pulmonary arterial and systemic plasma aldosterone levels associate with impaired cardiac reserve capacity during exercise in left ventricular systolic heart failure patients: A pilot study

    Article • The Journal of Heart and Lung Transplantation, March 2016, Elsevier

    William Oldham

  9. Pulmonary Hypertension as a Metabolic Disease

    Article • January 2016, Springer Science + Business Media

    William Oldham

  10. Protocol for Exercise Hemodynamic Assessment: Performing an Invasive Cardiopulmonary Exercise Test in Clinical Practice

    Article • Pulmonary Circulation, December 2015, SAGE Publications

    William Oldham

  11. Hypoxia-Mediated Increases in l -2-hydroxyglutarate Coordinate the Metabolic Response to Reductive Stress

    Article • Cell Metabolism, August 2015, Elsevier

    William Oldham

  12. Network-based association of hypoxia-responsive genes with cardiovascular diseases

    Article • New Journal of Physics, October 2014, Institute of Physics Publishing

    William Oldham

  13. Upregulation of Steroidogenic Acute Regulatory Protein by Hypoxia Stimulates Aldosterone Synthesis in Pulmonary Artery Endothelial Cells to Promote Pulmonary Vascular Fibrosis

    Article • Circulation, July 2014, Wolters Kluwer Health

    William Oldham

  14. A workshop on leadership for MD/PhD students

    Article • Medical Education Online, January 2011, Taylor & Francis

    William Oldham

  15. G   Activates GSK3 to Promote LRP6-Mediated  -Catenin Transcriptional Activity

    Article • Science Signaling, May 2010, American Association for the Advancement of Science

    William Oldham

  16. Helix Dipole Movement and Conformational Variability Contribute to Allosteric GDP Release in GαiSubunits†,‡

    Article • Biochemistry, March 2009, American Chemical Society (ACS)

    William Oldham

  17. Heterotrimeric G protein activation by G-protein-coupled receptors

    Article • Nature Reviews Molecular Cell Biology, January 2008, Springer Science + Business Media

    William Oldham

  18. Mapping allosteric connections from the receptor to the nucleotide-binding pocket of heterotrimeric G proteins

    Article • Proceedings of the National Academy of Sciences, May 2007, Proceedings of the National Academy of Sciences

    William Oldham

  19. How do Receptors Activate G Proteins?

    Article • January 2007, Elsevier

    William Oldham

  20. Structural and dynamical changes in an α-subunit of a heterotrimeric G protein along the activation pathway

    Article • Proceedings of the National Academy of Sciences, October 2006, Proceedings of the National Academy of Sciences

    William Oldham

  21. G-protein-coupled receptors: evolving views on physiological signalling: Symposium on G-Protein-Coupled Receptors: Evolving Concepts and New Techniques

    Article • EMBO Reports, August 2006, Wiley

    William Oldham

  22. Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins

    Article • Nature Structural & Molecular Biology, August 2006, Springer Science + Business Media

    William Oldham

  23. Structural basis of function in heterotrimeric G proteins

    Article • Quarterly Reviews of Biophysics, May 2006, Cambridge University Press

    William Oldham

  24. Direct Modulation of Phospholipase D Activity by Gβγ

    Article • Molecular Pharmacology, April 2006, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    William Oldham