All Stories

  1. Evaluating a custom GPT assistant for critical appraisal of biological variation studies by the BIVAC

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), July 2026, De Gruyter

    Dr William Alexander Bartlett

  2. Thyroid hormone profile and biological variation in a population of athletes during an entire sport season

    Article • Clinica Chimica Acta, June 2026, Elsevier

    Dr William Alexander Bartlett

  3. Novel biomarkers in bone pathophysiology: Establishing reference intervals and biological variations estimates for serum leptin, sclerostin, lipocalin-2, osteoprotegerin, resistin and Dickkopf-related protein-1 from the European biological variation st...

    Article • Clinica Chimica Acta, March 2025, Elsevier

    Dr William Alexander Bartlett

  4. Biological variation data. What's new.

    Article • Annals of Clinical Biochemistry International Journal of Laboratory Medicine, January 2025, SAGE Publications

    Dr William Alexander Bartlett

  5. Systematic review and meta-analysis of biological variation data of urine albumin, albumin to creatinine ratio and other markers in urine

    Article • Clinica Chimica Acta, January 2025, Elsevier

    Dr William Alexander Bartlett

  6. The biological variation of insulin resistance markers: data from the European Biological Variation Study (EuBIVAS)

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), July 2024, De Gruyter

    Dr William Alexander Bartlett

  7. A standard to report biological variation data studies – based on an expert opinion

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), July 2024, De Gruyter

    Dr William Alexander Bartlett

  8. Corrigendum to “The European biological variation study (EuBIVAS): Biological variation data for testosterone, follicle stimulating hormone, prolactin, luteinizing hormone and dehydroepiandrosterone sulfate in men” [Clin. Chim. Acta 555 (2024) 117806]

    Article • Clinica Chimica Acta, June 2024, Elsevier

    Dr William Alexander Bartlett

  9. A New Concept for Reference Change Values—Regression to the Population Mean

    Article • Clinical Chemistry, May 2024, Oxford University Press (OUP)

    Dr William Alexander Bartlett

  10. Analytical performance specifications based on biological variation data – considerations, strengths and limitations

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), March 2024, De Gruyter

    Dr William Alexander Bartlett

  11. The European biological variation study (EuBIVAS): Biological variation data for testosterone, follicle stimulating hormone, prolactin, luteinizing hormone and dehydroepiandrosterone sulfate in men

    Article • Clinica Chimica Acta, March 2024, Elsevier

    Dr William Alexander Bartlett

  12. Sex-related differences in within-subject biological variation estimates for 22 essential and non-essential amino acids

    Article • Clinica Chimica Acta, January 2024, Elsevier

    Dr William Alexander Bartlett

  13. Biological variation of inflammatory and iron metabolism markers in high-endurance recreational athletes; are these markers useful for athlete monitoring?

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), December 2023, De Gruyter

    Dr William Alexander Bartlett

  14. Biological variation estimates of Alzheimer's disease plasma biomarkers in healthy individuals

    Article • Alzheimer s & Dementia, November 2023, Wiley

    Dr William Alexander Bartlett

  15. Biological variation estimates of Alzheimer’s disease plasma biomarkers in healthy individuals

    Article • August 2023, Cold Spring Harbor Laboratory Press

    Dr William Alexander Bartlett

  16. Biological variation: recent development and future challenges

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), December 2022, De Gruyter

    Dr William Alexander Bartlett

  17. Critical review and meta-analysis of biological variation estimates for tumor markers

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), February 2022, De Gruyter

    Dr William Alexander Bartlett

  18. Long-term within- and between-subject biological variation of 29 routine laboratory measurands in athletes

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), November 2021, De Gruyter

    Dr William Alexander Bartlett

  19. Biological variation estimates of thyroid related measurands – meta-analysis of BIVAC compliant studies

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), November 2021, De Gruyter

    Dr William Alexander Bartlett

  20. Evidence-Based Introduction of Large-Scale Medical Technology Into Healthcare Through Test of Chance and Proof of Concept

    Article • Journal of Clinical Engineering, July 2021, Wolters Kluwer Health

    Dr William Alexander Bartlett

  21. The European Biological Variation Study (EuBIVAS): a summary report

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), May 2021, De Gruyter

    Dr William Alexander Bartlett

  22. Within- and between-subject biological variation data for tumor markers based on the European Biological Variation Study

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), May 2021, De Gruyter

    Dr William Alexander Bartlett

  23. Personalising laboratory medicine in the ‘real world’: Assessing clinical utility, by clinical indication, of serum total B12 and Active-B12® (holotranscobalamin) in the diagnosis of vitamin B12 deficiency

    Article • Annals of Clinical Biochemistry International Journal of Laboratory Medicine, April 2021, SAGE Publications

    Dr William Alexander Bartlett

  24. Biological Variation of Cardiac Troponins in Health and Disease: A Systematic Review and Meta-analysis

    Article • Clinical Chemistry, December 2020, Oxford University Press (OUP)

    Dr William Alexander Bartlett

  25. Critical appraisal and meta-analysis of biological variation estimates for kidney related analytes

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), October 2020, De Gruyter

    Dr William Alexander Bartlett

  26. Systematic review and meta-analysis of within-subject and between-subject biological variation estimates of 20 haematological parameters

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), December 2019, De Gruyter

    Abdurrahman Coskun, Dr William Alexander Bartlett

  27. Intelligent liver function testing (iLFT): A trial of automated diagnosis and staging of liver disease in primary care

    Article • Journal of Hepatology, October 2019, Elsevier

    Dr William Alexander Bartlett

  28. Biological variation data for lipid cardiovascular risk assessment biomarkers. A systematic review applying the biological variation data critical appraisal checklist (BIVAC)

    Article • Clinica Chimica Acta, August 2019, Elsevier

    Dr William Alexander Bartlett

  29. European Biological Variation Study (EuBIVAS): Within- and Between-Subject Biological Variation Data for 15 Frequently Measured Proteins

    Article • Clinical Chemistry, June 2019, AACC

    Dr William Alexander Bartlett

  30. Systematic review of the biological variation data for diabetes related analytes

    Article • Clinica Chimica Acta, January 2019, Elsevier

    Dr William Alexander Bartlett

  31. The EuBIVAS: Within- and Between-Subject Biological Variation Data for Electrolytes, Lipids, Urea, Uric Acid, Total Protein, Total Bilirubin, Direct Bilirubin, and Glucose

    Article • Clinical Chemistry, June 2018, AACC

    Dr William Alexander Bartlett

  32. PTU-132 Normal alt – missed opportunities to find fibrosis. lessons from ILFT

    Article • June 2018, BMJ

    Dr William Alexander Bartlett

  33. Within-subject and between-subject biological variation estimates of 21 hematological parameters in 30 healthy subjects

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), April 2018, De Gruyter

    Abdurrahman Coskun, Dr William Alexander Bartlett

  34. Intelligent liver function diagnostic pathway – Relevance of alanine transaminase normal values

    Article • Journal of Hepatology, April 2018, Elsevier

    Dr William Alexander Bartlett

  35. Harmonization initiatives in the generation, reporting and application of biological variation data

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), March 2018, De Gruyter

    Dr William Alexander Bartlett

  36. Development and validation of diagnostic triage criteria for liver disease from a minimum data set enabling the ‘intelligent LFT’ pathway for the automated assessment of deranged liver enzymes

    Article • Frontline Gastroenterology, February 2018, BMJ

    Dr William Alexander Bartlett

  37. Intelligent Liver Function Testing (iLFT): A Trial of Reflex Testing, Automated Diagnosis and Staging of Liver Disease

    Article • SSRN Electronic Journal, January 2018, Elsevier

    Dr William Alexander Bartlett

  38. A Critical Appraisal Checklist (BIVAC), to evaluate paper on Biological Variation

    Article • Clinical Chemistry, December 2017, AACC

    Abdurrahman Coskun, Dr William Alexander Bartlett, Anna Carobene, Pilar Fernandez-Calle

  39. Biological variation of serum creatinine

    Article • Clinical Chemistry, July 2017, AACC

    Prof Mustafa Serteser, Dr William Alexander Bartlett, Una Sølvik, Mario Plebani, Anna Carobene, Pilar Fernandez-Calle

  40. Biological Variation Estimates Obtained from 91 Healthy Study Participants for 9 Enzymes in Serum

    Article • Clinical Chemistry, April 2017, AACC

    Dr William Alexander Bartlett, Abdurrahman Coskun, Prof Mustafa Serteser, Mario Plebani, Anna Carobene, Pilar Fernandez-Calle

  41. Sample collections from healthy volunteers for biological variation estimates’ update: a new project undertaken by the Working Group on Biological Variation established by the European Federation of Clinical Chemistry and Laboratory Medicine

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2016, De Gruyter

    Abdurrahman Coskun, Prof Mustafa Serteser, Anna Carobene, Dr William Alexander Bartlett

  42. Biological variation: a still evolving facet of laboratory medicine

    Article • Annals of Clinical Biochemistry International Journal of Laboratory Medicine, March 2015, SAGE Publications

    Dr William Alexander Bartlett

  43. A checklist for critical appraisal of studies of biological variation

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2015, De Gruyter

    Abdurrahman Coskun, Dr William Alexander Bartlett

  44. A systematic review of data on biological variation for alanine aminotransferase, aspartate aminotransferase and γ-glutamyl transferase

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), January 2013, De Gruyter

    Dr William Alexander Bartlett

  45. The following abstracts were presented at the Annual Scientific Meeting of the Scottish Intensive Care Society in St Andrews, January 2012

    Article • Anaesthesia, April 2012, Wiley

    Dr William Alexander Bartlett

  46. Reflex and reflective testing: efficiency and effectiveness of adding on laboratory tests

    Article • Annals of Clinical Biochemistry International Journal of Laboratory Medicine, April 2010, SAGE Publications

    Dr William Alexander Bartlett

  47. UK Consensus Conference on Early Chronic Kidney Disease 6 and 7 February 2007

    Article • Nephrology Dialysis Transplantation, June 2007, Oxford University Press (OUP)

    Dr William Alexander Bartlett

  48. Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 Activityin VivoLimits Glucocorticoid Exposure to Human Adipose Tissue and Decreases Lipolysis

    Article • The Journal of Clinical Endocrinology & Metabolism, March 2007, Endocrine Society

    Dr William Alexander Bartlett

  49. Association between the cholesteryl ester transfer protein TaqI-detectable B polymorphism and low high-density lipoprotein cholesterol concentration in Saudis

    Article • Clinical Science, October 2003, Portland Press Ltd.

    Dr William Alexander Bartlett

  50. Serum leptin is elevated in Saudi Arabian patients with metabolic syndrome and coronary artery disease

    Article • Diabetic Medicine, September 2003, Wiley

    Dr William Alexander Bartlett

  51. 11β-Hydroxysteroid Dehydrogenase Type 1 Activity Predicts the Effects of Glucocorticoids on Bone

    Article • The Journal of Clinical Endocrinology & Metabolism, August 2003, Endocrine Society

    Dr William Alexander Bartlett

  52. Cardiovascular risk assessment in patients with retinal vein occlusion

    Article • British Journal of Ophthalmology, July 2002, BMJ

    Dr William Alexander Bartlett

  53. Osteoblastic 11β-Hydroxysteroid Dehydrogenase Type 1 Activity Increases With Age and Glucocorticoid Exposure

    Article • Journal of Bone and Mineral Research, June 2002, Wiley

    Dr William Alexander Bartlett

  54. Role of leptin in glucose metabolism in type 2 diabetes

    Article • Diabetes Obesity and Metabolism, May 2002, Wiley

    Dr William Alexander Bartlett

  55. Serum homocysteine concentration is related to diabetes mellitus, but not to coronary heart disease, in Saudi Arabians

    Article • Diabetes Obesity and Metabolism, March 2002, Wiley

    Dr William Alexander Bartlett

  56. Comparative accuracy of cardiovascular risk prediction methods in patients with diabetes mellitus

    Article • Diabetes Obesity and Metabolism, August 2001, Wiley

    Dr William Alexander Bartlett

  57. The sleep apnoea/hypopnoea syndrome depresses waking vagal tone independent of sympathetic activation

    Article • European Respiratory Journal, June 2001, European Respiratory Society (ERS)

    Dr William Alexander Bartlett

  58. Comparative accuracy of cardiovascular risk prediction methods in primary care patients

    Article • Heart, January 2001, BMJ

    Dr William Alexander Bartlett

  59. Assessment of coronary heart disease risk prediction in general practice-which table?

    Article • Atherosclerosis, July 2000, Elsevier

    Dr William Alexander Bartlett

  60. Standardization of HbA1c measurements

    Article • Diabetic Medicine, July 2000, Wiley

    Dr William Alexander Bartlett

  61. Laboratory‐based calculation of coronary heart disease risk in a hospital diabetic clinic

    Article • Diabetic Medicine, August 1999, Wiley

    Dr William Alexander Bartlett

  62. Plasma total homocysteine measurement by ion-paired reversed-phase hplc with electrochemical detection

    Article • Biomedical Chromatography, February 1999, Wiley

    Dr William Alexander Bartlett

  63. Glomerular filtration rate determination in diabetic patients using iohexol clearance — comparison of single and multiple plasma sampling methods

    Article • Clinica Chimica Acta, October 1998, Elsevier

    Dr William Alexander Bartlett

  64. The value of screening for Down's syndrome in a socioeconomically deprived area with a high ethnic population

    Article • BJOG An International Journal of Obstetrics & Gynaecology, August 1998, Wiley

    Dr William Alexander Bartlett

  65. A Non-Isotopic Method for Estimating 11β Hydroxysteroid Dehydrogenase Activity In Vivo

    Article • Annals of Clinical Biochemistry International Journal of Laboratory Medicine, September 1997, SAGE Publications

    Dr William Alexander Bartlett

  66. Ethnic differences in outcome of serum screening for Down's syndrome

    Article • BMJ, April 1996, BMJ

    Dr William Alexander Bartlett

  67. Measurement presents technical difficulties

    Article • BMJ, March 1996, BMJ

    Dr William Alexander Bartlett

  68. Plasma angiotensin-converting enzyme activity and carotid wall thickening.

    Article • Circulation, November 1994, Wolters Kluwer Health

    Dr William Alexander Bartlett

  69. Serum screening for Down's syndrome. Vacutainer system can lead to inaccurate results.

    Article • BMJ, October 1993, BMJ

    Dr William Alexander Bartlett

  70. Pure red-cell aplasia with fludarabine for chronic lymphocytic leukaemia

    Article • The Lancet, August 1993, Elsevier

    Dr William Alexander Bartlett

  71. Re‐evaluation of the captopril test for the diagnosis of primary hyperaldosteronism

    Article • Clinical Endocrinology, May 1992, Wiley

    Dr William Alexander Bartlett

  72. A case of skin hyperpigmentation due to α-MSH hypersecretion

    Article • British Journal of Dermatology, March 1992, Oxford University Press (OUP)

    Dr William Alexander Bartlett

  73. Interference of Fluorescein with Creatinine Assays

    Article • Annals of Clinical Biochemistry International Journal of Laboratory Medicine, March 1991, SAGE Publications

    Dr William Alexander Bartlett

  74. Effects of mobile phase composition on the chromatographic and electrochemical behaviour of catecholamines and selected metabolites

    Article • Journal of Chromatography B Biomedical Sciences and Applications, January 1989, Elsevier

    Dr William Alexander Bartlett

  75. DOSE REGIMENS OF HUMAN GROWTH HORMONE: EFFECTS OF CONTINUOUS INFUSION AND OF A GELATIN VEHICLE ON GROWTH IN RATS AND RATE OF ABSORPTION IN RABBITS

    Article • Journal of Endocrinology, November 1980, Bioscientifica

    Dr William Alexander Bartlett

  76. Neuroendocrine changes in acute schizophrenia as a function of clinical state and neuroleptic medication

    Article • Psychological Medicine, November 1978, Cambridge University Press

    Dr William Alexander Bartlett

  77. 2.4 Biological variation data: the need for appraisal of the evidence base

    Article • De Gruyter

    Dr William Alexander Bartlett